Research Topics
| Jürgen E ScholzeSummaryAffiliation: Humboldt University Country: Germany Publications
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Detail Information
Publications
Efficacy and safety of a fixed-dose combination of lercanidipine and enalapril in daily practice. A comparison of office, self-measured and ambulatory blood pressureJurgen Scholze
Centrum für Innere Medizin, Medizinische Poliklinik, Charite Campus Mitte, Luisenstr 11 13, 10117 Berlin, Germany
Expert Opin Pharmacother 12:2771-9. 2011..A fixed-dose combination (FDC) of enalapril and lercanidipine has been shown to be effective and safe in reducing blood pressure in randomized clinical trials. This study aims to determine effectiveness and safety in daily practice...
Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) studyJurgen Scholze
Department of Medicine, Outpatient Clinic, CCM, Charite Universitatsmedizin Berlin, Luisenstrasse 11 13, 10117 Berlin, Germany
Circulation 115:1991-8. 2007..To identify an optimal treatment regimen for obese hypertensive patients, we studied the interactions between a drug-based weight loss approach by sibutramine and different antihypertensive drug regimens...
[Hypertension associated with obesity]J Scholze
Campus Mitte/Medzinische Poliklinik,
MMW Fortschr Med 148:39-41. 2006
Initiation of hypertension treatment with a fixed-dose combination or its monocomponents -- does it really matter?J Scholze
University Hospital Charité Campus Charité Mitte Outpatient Department, Berlin, Germany
Int J Clin Pract 60:265-74. 2006..It can be concluded that initiating antihypertensive treatment with a low fixed-dose combination of ramipril/felodipine ER is more effective and safe when compared with treatment with its monocomponents...
[Cardiometabolic high risk patients with abdominal obesity. Frequency and risk factor profile in primary care]J Scholze
, Medizinische Poliklinik
MMW Fortschr Med 149:40. 2007
[Therapy of obesity-associated hypertension]J Scholze
Medizinische Poliklinik Center of Cardiovascular Research CCM
Dtsch Med Wochenschr 130:2645-50. 2005..Beta blockers should be used if definite cardiac indications are present...
[Pulse pressure in the therapeutic management of hypertension?]Jurgen Scholze
Medizinische Poliklinik, Ambulante Spezialmedizin, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin
Herz 29:276-89. 2004....
[Cardiometabolic high risk patients with abdominal obesity. Frequency and risk factor profile in primary care]Jurgen Scholze
Universitatsklinikum Charite, Campus Charite Mitte, Medizinische Poliklinik, Berlin
MMW Fortschr Med 149:103-10. 2007....
[Differential therapy with calcium antagonists]Jürgen E Scholze
Ambulante Spezialmedizin, Medizinische Universitätspoliklinik, Charité CCM, Berlin, Germany
Herz 28:754-63. 2003....
[The ALLHAT study (antihypertensive and lipid-lowering treatment to prevent heart attack trial): primary antihypertensive agents - diuretics vs calcium channel blockers vs angiotensin-converting enzyme inhibitors]J Scholze
Ambulante Spezialmedizin, Medizinische Poliklinik, , Germany
Internist (Berl) 44:1193-5. 2003
Safety and efficacy of olmesartan: an observational pooled-analysis of 156,682 hypertensive patientsJurgen Scholze
Centrum für Innere Medizin, Direktor Medizinische Poliklinik, Campus Mitte, Luisenstr 11 13, 10117 Berlin, Germany
Expert Opin Drug Saf 10:185-96. 2011..Angiotensin type 1 receptor blockers are recommended for first-line antihypertensive treatment...
[Treatment of hypertension in obesity]J Scholze
Medizinische Poliklinik, Campus Mitte, Charite, Berlin
Herz 26:209-21. 2001....
[Isolated systolic hypertension. An independent disease]J Scholze
Medizinische Poliklinik, Charite Universitatsmedizin Berlin, Luisenstr 11 13, 10117, Berlin
Herz 35:568-74. 2010..As a result of the available data from the results of treatment studies it appears that renin-angiotensin system (RAS) blockers and calcium channel blockers (CCBs) are the preferred drugs for treatment of this condition...
[Sibutramine in clinical practice - a PMS-study with positive effects on blood pressure and metabolic parameters]J Scholze
Ambulante Spezialmedizin, Medizinische Universitäts Poliklinik, Campus Charite Mitte, Berlin, Germany
Dtsch Med Wochenschr 127:606-10. 2002..As non-pharmacological therapies have failed to a large extent in the past, this post-marketing surveillance study was conducted to examine the feasibility, safety and efficacy of a medical weight reduction...
[Pitfalls in hypertension management--misjudgements in diagnosis and therapy]J Scholze
Medizinische Universitätspoliklinik Charité, Berlin, Germany
Dtsch Med Wochenschr 127:2383-6. 2002..These symptoms did not improve by changing her antihypertensive treatment. The patient's general condition was quite normal and there were no signs of acute or chronic cardiopulmonary decompensation...
Epidemiological and economic burden of metabolic syndrome and its consequences in patients with hypertension in Germany, Spain and Italy; a prevalence-based modelJurgen Scholze
Department of Medicine, Outpatient Clinic, CCM, Charite Universitatsmedizin Berlin, Luisenstrasse 11 13, 10117 Berlin, Germany
BMC Public Health 10:529. 2010..Our aim is to estimate the epidemiological and economic burden to the health service of metabolic syndrome in patients with hypertension in three European countries in 2008 and 2020...
Influence of Sibutramine on blood pressure: evidence from placebo-controlled trialsJ Jordan
Franz Volhard Clinical Research Center and HELIOS Klinikum, Medical Faculty of the Charite, Humboldt University, Berlin, Germany
Int J Obes (Lond) 29:509-16. 2005..Sibutramine, a serotonin and norepinephrine transporter inhibitor, is widely used as an adjunctive obesity treatment. There have been concerns that norepinephrine reuptake inhibition with sibutramine could exacerbate arterial hypertension...
The effect of oral glucose loads on tissue metabolism during angiotensin II receptor and beta-receptor blockade in obese hypertensive subjectsM Boschmann
Franz-Volhard Clinical Research Center, , Berlin, Berlin, Germany
Horm Metab Res 38:323-9. 2006..The exact mechanism by which inhibition of the renin-angiotensin-aldosterone system decreases the diabetes risk remains unresolved and requires further study...
Socio-economic status and the therapeutic effectiveness of antihypertensive treatment--the design of the LEO studyA C Schmidt
Charite Universitaetsmedizin, Department of Internal Medicine, Outpatient Clinic, Berlin, Germany
Curr Med Res Opin 23:1987-95. 2007..The angiotensin receptor blocker (ARB) olmesartan will be used to investigate the effectiveness of this drug in different socio-economic classes...
Dissemination of a Sjögren's syndrome-associated extranodal marginal-zone B cell lymphoma: circulating lymphoma cells and invariant mutation pattern of nodal Ig heavy- and light-chain variable-region gene rearrangementsA Hansen
Dept of Medicine and Outpatient Department, Charite Universitatsmedizin Berlin, Schumannstrasse 20 21, 10098 Berlin, Germany
Arthritis Rheum 54:127-37. 2006..We undertook this study to analyze lymphoma progression and dissemination outside of the MALT-type lesions...
[Multifocal nodular fatty infiltration of the liver associated with porphyria and haemochromatosis]U Daberkow
Medizinische Poliklinik, Ambulante Spezialmedizin, Universitatsklinikum Charite, Campus Mitte, Berlin
Dtsch Med Wochenschr 129:617-20. 2004..Diabetes mellitus was diagnosed 22 years ago. Clinical evaluation revealed a mild obesity and a facial hypertrichosis...
Comparison of immunoglobulin heavy chain rearrangements between peripheral and glandular B cells in a patient with primary Sjögren's syndromeA Hansen
Department of Medicine, University Hospital Charite, Schumannstr 20 21, D 10098 Berlin, Germany
Scand J Immunol 57:470-9. 2003..Notably, one of the glandular clonal rearrangements (using VH1-08) was also detected in the patient's peripheral repertoire...
Preactivated monocytes from hypertensive patients as a factor for atherosclerosis?Y Dörffel
Outpatient Clinics of Internal Medicine, Charite, Medical Faculty, Humboldt University, Luisenstrasse 11 13, 10098 Berlin, Germany
Atherosclerosis 157:151-60. 2001..In monocytes, peak levels of PMA and Ang II induced CL analysis were significantly higher in patients (P<0.005). These data indicate that preactivated monocytes from hypertensives may be of pathogenic importance in atherosclerosis...
Preactivated peripheral blood monocytes in patients with essential hypertensionY Dörffel
Outpatient Clinics of Internal Medicine, Department of Rheumatology and Clinical Immunology, Charite University Hospital, Humboldt University, Berlin, Germany
Hypertension 34:113-7. 1999..Our results indicate preactivated peripheral blood monocytes in hypertensive patients. Ang II may be directly involved in the process of monocyte activation...
[Blood pressure lowering and risk reduction under treatment with valsartan and its combination with hydrochlorothiazide (HCT)]J Scholze
, Campus Mitte, Medizinische Poliklinik, Luisenstr. 11-13 D-ll117, Berlin
MMW Fortschr Med 148:48. 2006
Choice of drug treatment for obesity-related hypertension: where is the evidence?A M Sharma
Franz Volhard Klinik, Max Delbruck Centre for Molecular Medicine, Berlin, Germany
J Hypertens 19:667-74. 2001....
