Research Topics
Genomes and GenesSpecies | D KunzSummaryAffiliation: Humboldt University Country: Germany Publications
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Detail Information
Publications
Perception of sleep: subjective versus objective sleep parameters in patients with Parkinson's disease in comparison with healthy elderly controls. Sleep perception in Parkinson's disease and controlsSvenja Happe
Dept of Clinical Neurology, University of Vienna, Vienna, Austria
J Neurol 252:936-43. 2005..Little is known about subjective sleep perception in patients with chronic somatic diseases...
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorderDieter Kunz
Institute of Physiology, Charite, Campus Benjamin Franklin, Universitatsmedizin Berlin, Berlin, Germany
J Sleep Res 19:591-6. 2010..e. during melatonin treatment). The data suggest that melatonin might be a second useful agent besides clonazepam in the treatment of RBD...
Melatonin in patients with reduced REM sleep duration: two randomized controlled trialsDieter Kunz
Department of Psychiatry and Psychotherapy, Charité Campus Mitte Universitätsmedizin Berlin, 10117 Berlin, Germany
J Clin Endocrinol Metab 89:128-34. 2004..It may, therefore, have a strong impact on general health, especially in the elderly and in shift workers...
Chronobiotic protocol and circadian sleep propensity index: new tools for clinical routine and research on melatonin and sleepD Kunz
Dept of Psychiatry and Psychotherapy, Charité Campus Mitte Universitätsmedizin
Pharmacopsychiatry 37:139-46. 2004....
Delta-9-tetrahydrocannabinol for nighttime agitation in severe dementiaSebastian Walther
Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charité Mitte PUK, Berlin, Germany
Psychopharmacology (Berl) 185:524-8. 2006..Nighttime agitation occurs frequently in patients with dementia and represents the number one burden on caregivers today. Current treatment options are few and limited due to substantial side effects...
Self-reported empathic abilities in schizophreniaC Montag
Klinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
Schizophr Res 92:85-9. 2007..e. cognitive aspects of mental state attribution, the ability to infer emotional experiences of others, i.e. affective empathy, has not been investigated so far...
Association between cerebral glutamate and human behaviour: the sensation seeking personality traitJ Gallinat
Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Mitte, University Hospital of Dresden, Germany
Neuroimage 34:671-8. 2007..However, the role of glutamate in related personality traits like sensation seeking has not been investigated in humans...
Hippocampal glutamate concentration predicts cerebral theta oscillations during cognitive processingJ Gallinat
Clinic for Psychiatry and Psychotherapy PUK im SHK, Charite University Medicine Berlin, Campus Mitte, St Hedwig Krankenhaus, Turmstrasse 21, 10559 Berlin, Germany
Psychopharmacology (Berl) 187:103-11. 2006..Human evidence for such relationships is lacking...
Serotonergic effects of smoking are independent from the human serotonin transporter gene promoter polymorphism: evidence from auditory cortical stimulus processingJ Gallinat
Clinic for Psychiatry and Psychotherapy, Charite University Medicine, Campus Mitte, Berlin, Germany
Pharmacopsychiatry 38:158-60. 2005..Moreover, smoking behavior has been associated to the 5-HTT-genotype. It was hypothesized that cigarette smoking modulates the LD and this effect was expected to interact with the 5-HTT-genotype...
Examining the gateway to the limbic system with diffusion tensor imaging: the perforant pathway in dementiaPeter Kalus
Department of Psychiatry, Charite University Medicine, Campus Mitte, Berlin, Germany
Neuroimage 30:713-20. 2006..DTI of medial temporal brain regions is a promising non-invasive tool for the in vivo diagnosis of the early/preclinical stages of AD...
Degree of pineal calcification (DOC) is associated with polysomnographic sleep measures in primary insomnia patientsRichard Mahlberg
Department of Physiology, Charite Campus Benjamin Franklin, Charite Universitatsmedizin Berlin, D 14195 Berlin, Germany
Sleep Med 10:439-45. 2009..The aim of our study was, therefore, to determine the relationship between the degree of pineal calcification (DOC) and a range of sleep parameters measured objectively using polysomnography (PSG)...
Pineal calcification in Alzheimer's disease: an in vivo study using computed tomographyRichard Mahlberg
Department of Psychiatry and Psychotherapy, Charite Campus Mitte, Charite Universitatsmedizin Berlin, Turmstrasse 21, D 10559 Berlin, Germany
Neurobiol Aging 29:203-9. 2008..On the other hand, the relative reduction in melatonin production capability in the individual, as indicated by DOC, refers to the circadian properties of melatonin...
Melatonin excretion levels and polysomnographic sleep parameters in healthy subjects and patients with sleep-related disturbancesRichard Mahlberg
Department of Psychiatry and Psychotherapy, Charite Campus Mitte, Charite Universitatsmedizin Berlin, Grosse Hamburger Strasse 5 11, D 10115 Berlin, Germany
Sleep Med 8:512-6. 2007..Exogenous melatonin has been shown to be beneficial in cases of CTS dysfunction and sleep disturbances. The aim of our study was to relate 24-h melatonin excretion to objective sleep measures...
Effects of rivastigmine on actigraphically monitored motor activity in severe agitation related to Alzheimer's disease: a placebo-controlled pilot studyRichard Mahlberg
Department of Psychiatry and Psychotherapy, Charite Campus Mitte, Charite Universitatsmedizin Berlin, Turmstr 21, D 10559 Berlin, Germany
Arch Gerontol Geriatr 45:19-26. 2007..Because rivastigmine usually exerts its main effects after a longer period of time, the short-term effects seen in our study justify further controlled clinical trials examining the use of rivastigmine in BPSD by means of actigraphy...
Normative data on the daily profile of urinary 6-sulfatoxymelatonin in healthy subjects between the ages of 20 and 84Richard Mahlberg
Department of Psychiatry and Psychotherapy, Charite Campus Mitte, Charite, Universitatsmedizin Berlin, Turmstr 21, D 10559 Berlin, Germany
Psychoneuroendocrinology 31:634-41. 2006..The high inter-individual variability of excretion rates may explain why a normative data set is of no use in replacement strategies...
Interrater reliability between scorers from eight European sleep laboratories in subjects with different sleep disordersHeidi Danker-Hopfe
Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
J Sleep Res 13:63-9. 2004..These variations of IRR most probably reflect changes of the sleep electroencephalography (EEG) with age and gender...
[Restless legs syndrome, periodic limb movements, and psychopharmacology]S Cohrs
AG Schlafforschung and Klinische Chronobiologie, Institut fur Physiologie, Charite, Universitatsmedizin Berlin, Berlin, Germany
Nervenarzt 79:1263-4, 1266-72. 2008..In case of RLS/PLMD occurring in psychotic patients switching the antipsychotic and additionally using a second line medication such as antiepileptics or a benzodiazepine should be considered...
Computed tomography of the human pineal gland for study of the sleep-wake rhythm: reproducibility of a semi-quantitative approachS A Schmitz
Department of Radiology and Nuclear Medicine, , Campus Benjamin Franklin, Berlin, Germany
Acta Radiol 47:865-71. 2006..These data support the use of thin slices of 1 and 2 mm. The benefit in reproducibility from thin slices has to be carefully weighted against their considerably higher radiation exposure...
The Double Sensor-A non-invasive device to continuously monitor core temperature in humans on earth and in spaceH C Gunga
Department of Physiology, Center of Space Medicine, Berlin, Germany
Respir Physiol Neurobiol 169:S63-8. 2009..Yet, it seems to be a valid, non-invasive alternative for monitoring circadian rhythm profiles...
Melatonin treatment of day-night rhythm disturbances and sundowning in Alzheimer disease: an open-label pilot study using actigraphyRichard Mahlberg
J Clin Psychopharmacol 24:456-9. 2004
An E-health solution for automatic sleep classification according to Rechtschaffen and Kales: validation study of the Somnolyzer 24 x 7 utilizing the Siesta databasePeter Anderer
Department of Psychiatry, Medical University of Vienna, Vienna, Austria
Neuropsychobiology 51:115-33. 2005..5% of the recordings) are changed, can definitely be neglected. Thus, the validation study proved the high reliability and validity of the Somnolyzer 24 x 7 and demonstrated its applicability in clinical routine and sleep studies...
Molecular insights into human daily behaviorSteven A Brown
Laboratory of Chronobiology, Charite Universitatsmedizin Berlin, Hessische Strasse 3 4, D 10115 Berlin, Germany
Proc Natl Acad Sci U S A 105:1602-7. 2008..In many instances, these changes can be studied at the molecular level in primary dermal cells...
How long should the lithium augmentation strategy be maintained? A 1-year follow-up of a placebo-controlled study in unipolar refractory major depressionTom Bschor
Department of Psychiatry, , Dresden, Germany
J Clin Psychopharmacol 22:427-30. 2002..Study data suggest that active medication should be maintained for at least 1 year after successful lithium augmentation in patients with unipolar major depressive disorder...
