Research Topics
Species | Arne HansenSummaryAffiliation: Humboldt University Country: Germany Publications
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Detail Information
Publications
Dysregulation of chemokine receptor expression and function by B cells of patients with primary Sjögren's syndromeArne Hansen
Department of Medicine, Outpatient Department, Charite University Hospital, Berlin, Germany
Arthritis Rheum 52:2109-19. 2005..To assess whether abnormal chemokine receptor expression and/or abnormal responsiveness to the cognate ligands might underlie some of the disturbances in B cell homeostasis characteristic of primary Sjögren's syndrome (SS)...- B cells in Sjögren's syndrome: indications for disturbed selection and differentiation in ectopic lymphoid tissueArne Hansen
Charite Center CC 12, Department of Medicine, Charite Universitatsmedizin Berlin, Charité Platz 01, 10098 Berlin, Germany
Arthritis Res Ther 9:218. 2007..These findings add to our understanding of the pathogenesis of this autoimmune inflammatory disorder and may result in new therapeutic approaches... - B-cell lymphoproliferation in chronic inflammatory rheumatic diseasesArne Hansen
Outpatients Department of Medicine, Charite University Hospital, Berlin, Germany
Nat Clin Pract Rheumatol 3:561-9. 2007..This Review will focus on the risk of lymphoma, common and disease-specific mechanisms of B-cell lymphoma development, and on the clinical consequences of lymphoma in patients with inflammatory rheumatic diseases... - Abnormalities in peripheral B cell memory of patients with primary Sjögren's syndromeArne Hansen
Department of Medicine Outpatients Department, Charite University Hospital, Berlin, Germany
Arthritis Rheum 50:1897-908. 2004..To delineate disturbances in peripheral B cell memory in primary Sjögren's syndrome (SS)... - New concepts in the pathogenesis of Sjögren syndrome: many questions, fewer answersArne Hansen
Charite University Hospital, Berlin, Germany
Curr Opin Rheumatol 15:563-70. 2003..As demonstrated by the introduction of the new targeted therapeutic approaches in rheumatoid arthritis, solid insights into the pathogenesis of Sjögren syndrome may pave the way toward new therapeutic approaches... - Developments in lupus 2006Arne Hansen
Charite Centrum 12, Charite University Medicine, Chariteplatz 01, 10098 Berlin, Germany
Arthritis Res Ther 9:215. 2007..Although it remains to be shown which of those could be targets for therapy or biomarkers, lymphocyte-directed therapy is currently under promising clinical investigation... - Diminished peripheral blood memory B cells and accumulation of memory B cells in the salivary glands of patients with Sjögren's syndromeArne Hansen
University Hospital Charit, Berlin, Germany
Arthritis Rheum 46:2160-71. 2002..It is possible that preferential accumulation of CD27+ memory B cells in the inflamed parotid gland explains their reduction in the peripheral blood... - Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: delineation by expression of CD27, IgD, and CD95Annett M Jacobi
Charite Universitatsmedizin Berlin, Berlin, Germany
Arthritis Rheum 58:1762-73. 2008..Focusing on CD27- B cells, this study aimed to identify abnormalities in peripheral B cell subsets in patients with SLE... - Chronic lymphocytic leukemia preceded by cold agglutinin disease: intraclonal immunoglobulin light-chain diversity in V(H)4-34 expressing single leukemic B cellsSarka Ruzickova
Deutsches Rheumaforschungszentrum, Berlin, Germany
Blood 100:3419-22. 2002..Of note, our findings suggest that this B-CLL had developed from the patient's CA-producing B-cell population... - Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune responseMarcus Odendahl
Department of Medicine, Charit, Humbold University, D-10117 Berlin, Germany
Blood 105:1614-21. 2005.... - Role of the spleen in peripheral memory B-cell homeostasis in patients with autoimmune thrombocytopenia purpuraLorena Martinez-Gamboa
Charité Center 14 for Tumor Medicine, Institute for Transfusion Medicine and Immune Hematology, Charite University Hospital, Berlin, Germany
Clin Immunol 130:199-212. 2009..Thus, the spleen plays a fundamental role in controlling peripheral memory B cell homeostasis in both AITP and HD and regulates activated CD95+ B cells in patients with AITP... - Immunglobulin repertoire analysis provides new insights into the immunopathogenesis of Sjögren's syndromeThomas Dorner
Department of Medicine, Rheumatology and Clinical Immunology, University Hospital Charite, Schumannstrasse 20 21, 10098 Berlin, Germany
Autoimmun Rev 1:119-24. 2002..The nature of the influences that lead to disordered selection in pSS remains to be determined, but should provide important clues to the etiology of this autoimmune inflammatory disorder... - Cryopreserved human B cells as an alternative source for single cell mRNA analysisArne Hansen
Outpatients Department of Medicine, Charite University Medicine Berlin, Germany
Cell Tissue Bank 6:299-308. 2005..However, the settings for both FACS analysis and RT-PCR should be re-evaluated for each distinct subpopulation and target mRNA of interest when analyzing post-thawed cells... - What do we know about memory B cells in primary Sjögren's syndrome?Arne Hansen
Department of Medicine, Park Klinik Weissensee, Berlin, Germany
Autoimmun Rev 9:600-3. 2010..Thus, B cells may be potential targets of direct or indirect treatment in pSS... - Epratuzumab targeting of CD22 affects adhesion molecule expression and migration of B-cells in systemic lupus erythematosusCapucine Daridon
Charite Universitatsmedizin Berlin, CC12 Dept, Medicine Rheumatology and Clinical Immunology, Chariteplatz 1, Berlin 10117, Germany
Arthritis Res Ther 12:R204. 2010..Therefore, potential effects of epratuzumab on adhesion molecule expression and the migration of B-cells have been evaluated... - A method for the determination of the residual chloroform in defatted cancellous bone transplantsUlrich Kalus
Institute for Transfusion Medicine Tissue Bank, University Hospital Charite, Berlin, Germany
Cell Tissue Bank 6:71-5. 2005..For the necessary routine quality checks on the production process, a gas chromatography method has been developed that determines the level of chloroform in cancellous bone, for which the detection limit is 0.003 ppm... - Immunopathogenesis of primary Sjögren's syndrome: implications for disease management and therapyArne Hansen
Charite University Medicine Berlin, Germany
Curr Opin Rheumatol 17:558-65. 2005..This review highlights recent advances in understanding the underlying mechanisms of the disease as well as their implications for clinical handling and therapeutic options... - Analysis of immunoglobulin light chain rearrangements in the salivary gland and blood of a patient with Sjögren's syndromeAnnett M Jacobi
Department of Internal Medicine/Rheumatology and Clinical Immunology, Charite University Hospital, Berlin, Germany
Arthritis Res 4:R4. 2002..These results suggest a role of antigen-activated and selected B cells in the local autoimmune process in SS... - Peracetic acid-ethanol treatment of allogeneic avital bone tissue transplants--a reliable sterilization methodAxel Pruss
Institute for Transfusion Medicine Tissue Bank, University Hospital Charite, Berlin, Germany
Ann Transplant 8:34-42. 2003.... - Using brain slice cultures of mouse brain to assess the effect of growth factors on differentiation of bone marrow derived stem cellsAndras Bratincsak
National Institute of Mental Health, National Institutes of Health, Bethesda, USA
Ideggyogy Sz 60:124-9. 2007..Once such factors have been identified they could be evaluated for tissue regeneration in more complex, whole animal models...