Research Topics
| U B HofmannSummaryCountry: Germany Publications
| Collaborators |
Detail Information
Publications
Matrix metalloproteinases in human melanomaU B Hofmann
Department of Pathology, University Hospital, Nijmegen, The Netherlands
J Invest Dermatol 115:337-44. 2000....
Coexpression of integrin alpha(v)beta3 and matrix metalloproteinase-2 (MMP-2) coincides with MMP-2 activation: correlation with melanoma progressionU B Hofmann
Department of Pathology and Surgery, University Hospital, Nijmegen, The Netherlands
J Invest Dermatol 115:625-32. 2000..These findings strongly suggest that co-ordinated expression of both factors may be required for melanoma cell invasion and metastasis formation...
[Role of matrix-degrading enzymes in melanoma progression]U B Hofmann
Universitätsklinik und Poliklinik für Hautkrankheiten, Julius Maximilians Universitat, Wurzburg, Germany
Hautarzt 53:587-95. 2002..In this review we discuss these functional aspects of melanoma progression...
Calcitriol vs. dithranol in combination with narrow-band ultraviolet B (311 nm) in psoriasisU B Hofmann
Department of Dermatology, University of Wurzburg, Josef Schneider Str 2, D 97080 Wurzburg, Germany
Br J Dermatol 148:779-83. 2003..In order to reduce cumulative UV doses and to enhance clearance of psoriasis plaques, combination therapies with topical agents such as dithranol and calcipotriol have been established...
Expression and activation of matrix metalloproteinase-2 (MMP-2) and its co-localization with membrane-type 1 matrix metalloproteinase (MT1-MMP) correlate with melanoma progressionU B Hofmann
Department of Pathology, University Hospital, Nijmegen, The Netherlands
J Pathol 191:245-56. 2000....
Expression of integrin alpha(v)beta(3) correlates with activation of membrane-type matrix metalloproteinase-1 (MT1-MMP) and matrix metalloproteinase-2 (MMP-2) in human melanoma cells in vitro and in vivoU B Hofmann
Department of Pathology, University Hospital, Nijmegen, The Netherlands
Int J Cancer 87:12-9. 2000..Furthermore, MT1-MMP and alpha(v)beta(3) are co-localized on the cell membrane of tumor cells. These findings suggest that activated MT1-MMP co-localized with alpha(v)beta(3) may be involved in activation of alpha(v)beta(3)-bound MMP-2...
Matrix metalloproteinases in human melanoma cell lines and xenografts: increased expression of activated matrix metalloproteinase-2 (MMP-2) correlates with melanoma progressionU B Hofmann
Department of Pathology, University Hospital, Nijmegen, The Netherlands
Br J Cancer 81:774-82. 1999....
[Nevus of Ota and choroid melanoma]P Terheyden
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Hautarzt 52:803-6. 2001..Although the nevus of Ota is rare in Caucasians, associated melanoma is more common than in Asians or black people. The dermatologist should be aware of this problem and aim at an interdisciplinary management of these patients...
