Research Topics
| Dirk Matthias HermannSummaryCountry: Germany Publications
| Collaborators
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Detail Information
Publications
Implications of vascular endothelial growth factor for postischemic neurovascular remodelingDirk Matthias Hermann
Department of Neurology, University Hospital Essen, University of Duisburg Essen, Essen, Germany
J Cereb Blood Flow Metab 29:1620-43. 2009..Only on the basis of such information can more definite conclusions be made with regard to whether the translation of therapeutic angiogenesis into clinics is promising...
Promoting brain remodelling and plasticity for stroke recovery: therapeutic promise and potential pitfalls of clinical translationDirk M Hermann
Department of Neurology, University Hospital Essen, Essen, Germany
Lancet Neurol 11:369-80. 2012..Balancing the opportunities and possible risks, we provide suggestions for the translation of restorative therapies from the laboratory to the clinic...
Enhancing the delivery of erythropoietin and its variants into the ischemic brainDirk M Hermann
Department of Neurology, University Hospital Essen, Germany
ScientificWorldJournal 9:967-9. 2009....
Sleep-related breathing and sleep-wake disturbances in ischemic strokeDirk M Hermann
Department of Neurology, University Hospital Essen, Essen, Germany
Neurology 73:1313-22. 2009..Sleep-related breathing disturbances (SDB) and sleep-wake disturbances (SWD) are often neglected in stroke patients. Recent studies suggest that they are frequent and have an impact on stroke outcome...
Nonhematopoietic variants of erythropoietin in ischemic stroke: need for step-wise proof-of-concept studiesDirk M Hermann
Department of Neurology, University Hospital Essen, Germany
ScientificWorldJournal 10:2285-7. 2010..Only with such information should decisions be made whether intranasal Neuro-EPO may be evaluated in human patients...
Future Perspectives for Brain Pharmacotherapies: Implications of Drug Transport Processes at the Blood-brain BarrierDirk M Hermann
Chair of Vascular Neurology and Dementia, Department of Neurology, University Hospital Essen, Essen, Germany
Ther Adv Neurol Disord 1:167-79. 2008..As such, restorative and anti-inflammatory strategies acting at the blood-brain interface might gain therapeutic potential in the future...
Post-acute delivery of erythropoietin induces stroke recovery by promoting perilesional tissue remodelling and contralesional pyramidal tract plasticityRaluca Reitmeir
Dementia and Ageing Disorders, Department of Neurology, University Hospital Essen, Hufelandstr 55, D 45122 Essen, Germany
Brain 134:84-99. 2011..Our study establishes a plasticity-promoting effect of erythropoietin after stroke, indicating that erythropoietin acts via recruitment of contralesional rather than of ipsilesional pyramidal tract projections...
ATP-binding cassette transporters at the blood-brain barrier in ischaemic strokePauline Patak
Department of Neurology, University Hospital Essen, Germany
Curr Pharm Des 17:2787-92. 2011....
Combination of tissue-plasminogen activator with erythropoietin induces blood-brain barrier permeability, extracellular matrix disaggregation, and DNA fragmentation after focal cerebral ischemia in miceAnil Zechariah
Department of Neurology, University Hospital Essen, Hufelandstrasse 55, D 45122 Essen, Germany
Stroke 41:1008-12. 2010..The reasons for the adverse effects of EPO in t-PA-treated patients are unknown...
