Research Topics
| Reinhard DenglerSummaryAffiliation: Hannover Medical School Country: Germany Publications
| Collaborators
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Detail Information
Publications
Early treatment with aspirin plus extended-release dipyridamole for transient ischaemic attack or ischaemic stroke within 24 h of symptom onset (EARLY trial): a randomised, open-label, blinded-endpoint trialReinhard Dengler
Department of Neurology, Medizinische Hochschule Hannover, Hannover, Germany
Lancet Neurol 9:159-66. 2010..The EARLY trial aimed to compare outcome in patients given aspirin plus extended-release dipyridamole twice daily either within 24 h of stroke or TIA or after 7 days of aspirin monotherapy...
Intertemporal choice in Parkinson's diseaseMaria Milenkova
Department of Neurology, Medical School Hannover, Hannover, Germany
Mov Disord 26:2004-10. 2011..This needs to be addressed in further studies. The paradigm used is easy to apply and should be used more extensively to describe decision behavior in Parkinson's disease...
Intraspinal injection of human umbilical cord blood-derived cells is neuroprotective in a transgenic mouse model of amyotrophic lateral sclerosisSarah Knippenberg
Department of Neurology, Hannover Medical School, Hannover, Germany
Neurodegener Dis 9:107-20. 2012..Adult stem cells have recently come into the focus of neurological research. While replacement of motor neurons by stem cells currently appears not feasible, there is evidence that non-neuronal cells can be neuroprotective...
Changes in resting-state brain networks in writer's crampBahram Mohammadi
Department of Neurology, University of Lubeck, Lubeck, Germany
Hum Brain Mapp 33:840-8. 2012..To circumvent this problem, we examined WC patients during rest, i.e., without a task, using independent component analysis (ICA) applied to the blood oxygen level-dependent time series...
Value of quantitative analysis of routine clinical MRI sequences in ALSXiao Qi Ding
Institute of Diagnostic and Interventional Neuroradiology, Hannover, Germany
Amyotroph Lateral Scler 12:406-13. 2011..PD therefore appeared to be the most sensitive parameter for the detection of degenerative changes not only in the motor system but also in extramotor brain regions...
Nerve compression syndromes in ALS: a retrospective analysis in 554 patientsKatja Kollewe
Department of Neurology and Clinical Neurophysiology, Medical School of Hannover, Hannover, Germany
Amyotroph Lateral Scler 12:349-51. 2011..32) of the diagnosis of ALS. Survival was no different between group A and the cohort. It can also be concluded that the misdiagnoses could have been avoided by thorough electrophysiological examination using a standardized protocol...
Cortical processing of swallowing in ALS patients with progressive dysphagia--a magnetoencephalographic studyInga K Teismann
Department of Neurology, University of Muenster, Muenster, Germany
PLoS ONE 6:e19987. 2011..These results add new aspects to our understanding of the pathophysiology of dysphagia in ALS patients and beyond. The compensational mechanisms observed could be relevant for future research in swallowing therapies...
Patterns of cortical activity differ in ALS patients with limb and/or bulbar involvement depending on motor tasksKatja Kollewe
Department of Neurology and Clinical Neurophysiology, Medical School of Hannover, Hannover, Germany
J Neurol 258:804-10. 2011..Thus, two different patterns of cortical activation changes suggesting fundamental differences in the neurodegenerative process and subsequent reorganisation processes exist for limb and bulbar movements...
Onset and spreading patterns of upper and lower motor neuron symptoms in amyotrophic lateral sclerosisSonja Körner
Department of Neurology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
Muscle Nerve 43:636-42. 2011..There is ongoing discussion as to whether ALS is primarily a disease of UMNs or LMNs...
Intramedullary spinal cord implantation of human CD34+ umbilical cord-derived cells in ALSAnna Lena Cordes
Departments of Neurology, Hannover, Germany
Amyotroph Lateral Scler 12:325-30. 2011....
Lateral frontal cortex volume reduction in Tourette syndrome revealed by VBMMatthias Wittfoth
Department of Neurology, Hannover Medical School, Hannover, Germany
BMC Neurosci 13:17. 2012....
Chronic deep brain stimulation in patients with tardive dystonia without a history of major psychosisHans Holger Capelle
Department of Neurosurgery, Medical School Hannover, MHH, Hannover, Germany
Mov Disord 25:1477-81. 2010..This effect is stable on extended follow-up for up to 3 years...
Significance of behavioural tests in a transgenic mouse model of amyotrophic lateral sclerosis (ALS)Sarah Knippenberg
Hannover Medical School, Department of Neurology, Carl Neuberg Str 1, 30625, Hannover, Germany
Behav Brain Res 213:82-7. 2010..For preclinical testing of novel drug treatments rotarod and footprint analysis for step length therefore seem to be the most effective methods to detect symptom onset and potential treatment induced improvements...
Changes of emotional prosody in Parkinson's diseaseChristine Schröder
Department of Neurology, Medical School Hannover, Hannover, Germany
J Neurol Sci 289:32-5. 2010..Together, these studies highlight the importance of the basal ganglia and their connections for emotional communication...
Frequency and treatment of depressive symptoms in a Parkinson's disease registryAstrid Althaus
Department of Neurology, Philipps University of Marburg, Germany
Parkinsonism Relat Disord 14:626-32. 2008..Large scale randomized controlled trials examining efficacy and safety of antidepressants in PD patients are urgently required...
