Research Topics
Species | F HallerSummaryCountry: Germany Publications
| Collaborators |
Detail Information
Publications
Increased KIT signalling with up-regulation of cyclin D correlates to accelerated proliferation and shorter disease-free survival in gastrointestinal stromal tumours (GISTs) with KIT exon 11 deletionsF Haller
Department of Pathology, Georg August University, Gottingen, Germany
J Pathol 216:225-35. 2008..Altogether, these observations suggest increased KIT signalling with up-regulation of cyclin D as the basis for the unfavourable clinical course in GISTs with KIT exon 11 deletions...
Localization- and mutation-dependent microRNA (miRNA) expression signatures in gastrointestinal stromal tumours (GISTs), with a cluster of co-expressed miRNAs located at 14q32.31Florian Haller
Department of Pathology, Georg August University, Gottingen, Germany
J Pathol 220:71-86. 2010..miRNA profiling may prove to be a key determinant of the biology and clinical features of GISTs...
Loss of 9p leads to p16INK4A down-regulation and enables RB/E2F1-dependent cell cycle promotion in gastrointestinal stromal tumours (GISTs)F Haller
Department of Pathology, Georg August University, Gottingen, Germany
J Pathol 215:253-62. 2008..This study provides a possible basis for the accelerated proliferation and particularly malignant behaviour in GISTs with 9p loss...
Increased number of mature dendritic cells in Crohn's disease: evidence for a chemokine mediated retention mechanismP Middel
Department of Pathology, Georg August Universitat Gottingen, Robert Koch Str 40, 37073 Gottingen, Germany
Gut 55:220-7. 2006..Detailed analyses however concerning the phenotype and maturation of DC as well as the mechanisms underlying their recruitment are still lacking for Crohn's disease...
An oncogenetic tree model in gastrointestinal stromal tumours (GISTs) identifies different pathways of cytogenetic evolution with prognostic implicationsB Gunawan
Institute of Pathology, Department of General Surgery, University of Gottingen, Germany, and Department of Clinical Pathology and Cytology, Merkur University Hospital, Zagreb, Croatia
J Pathol 211:463-70. 2007..Thus, insights into the cytogenetic evolution obtained from oncogenetic tree models may eventually help to gain a better understanding of the heterogeneous site-dependent biological behaviour of GISTs...
