Research Topics
| M GloorSummaryCountry: Germany Publications
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Detail Information
Publications
Anti-irritative effect of methylrosaniline chloride (Gentian violet)M Gloor
Department of Dermatology, Klinikum der Stadt Karlsruhe, Germany
Dermatology 203:325-8. 2001..A tissue-damaging effect has been described in animal studies and at higher concentrations in humans...
Keratolytic activity of microemulsionsM Gloor
Department of Dermatology, Karlsruhe Municipal Medical Center, Karlsruhe, Germany
Skin Pharmacol Appl Skin Physiol 16:151-5. 2003..To compare the keratolytic activities of a drug-free hydrophilic microemulsion (ME) and a drug-free lipophilic ME with water, and with regard to the hydrophilic ME also with a 5% salicylic acid gel on the sole of the foot...
How do dermatological vehicles influence the horny layer?M Gloor
Dermatological Department, City Hospital of Karlsruhe, Karlsruhe, Germany
Skin Pharmacol Physiol 17:267-73. 2004..A hydrating effect on the stratum corneum was also found in a propylene glycol ointment...
On the course of the irritant reaction after irritation with sodium lauryl sulphateMax Gloor
Department of Dermatology Municipal Hospital Karlsruhe GmbH, Germany
Skin Res Technol 10:144-8. 2004..The sodium lauryl sulphate (SLS) irritation test is a well-established model for irritant contact dermatitis after the effects of surfactants...
O/W emulsions compromise the stratum corneum barrier and improve drug penetrationM Gloor
Department of Dermatology, Klinikum der Stadt Karlsruhe GmbH, Germany
Pharmazie 58:709-15. 2003..W/O emulsions improve the stratum corneum barrier, while microemulsions tend to compromise it. We, therefore, were interested to explore the effects of O/W emulsions on the stratum corneum barrier...
[Effects of emulsions on the stratum corneum barrier and hydration]M Gloor
Hautklinik am Klinikum der Stadt Karlsruhe gGmbH
Hautarzt 54:324-30. 2003..Both types of microemulsions additionally lead to a dehydration of the stratum corneum. The damaging effect of oil-in-water-emulsions can be reduced by the addition of glycerol and urea...
[Triclosan, a topical dermatologic agent. In vitro- and in vivo studies on the effectiveness of a new preparation in the New German Formulary]M Gloor
Hautklinik am Klinikum der Stadt Karlsruhe, Germany
Hautarzt 53:724-9. 2002..The objective of the present study was to explore its potential utility in atopic dermatitis and prophylactic skin care following leg eczema and leg ulcer treatment...
Inhibition of lipase activity in antibiotic-resistant propionibacterium acnes strainsM Gloor
Department of Dermatology, Klinikum der Stadt Karlsruhe, Germany
Dermatology 205:260-4. 2002..The objective of this study was to determine whether erythromycin and clindamycin concentrations far below the MIC inhibit lipase production in P. acnes strains resistant to these antibiotics...
Age dependence of ultraviolet light-induced erythema following narrow-band UVB exposureM Gloor
Department of Dermatology, Klinikum der Stadt Karlsruhe gGmbH, Moltkestrasse 120, D 76133 Karlsruhe, Germany
Photodermatol Photoimmunol Photomed 18:121-6. 2002..The aim of this study was to identify differences in minimum erythema dose (MED) and intensity of UV-induced erythema after narrow band UVB exposure between older and younger individuals in the late phase of UVB erythema...
Antiseptic effect of a topical dermatological formulation that contains Hamamelis distillate and ureaM Gloor
Hautklinik, Stadtisches Klinikum Karlsruhe, Germany
Forsch Komplementarmed Klass Naturheilkd 9:153-9. 2002..To determine the antimicrobial activity of a distillate of Hamamelis (Aqua Hamamelidis ), United States Pharmacopoeia (USP) 23, and urea formulated as a topical dermatological preparation that contains both active ingredients...
Tolerance profile of retinol, retinaldehyde and retinoic acid under maximized and long-term clinical conditionsJ W Fluhr
Department of Dermatology, Klinikum Karlsruhe, Germany
Dermatology 199:57-60. 1999..To prevent this side effect, natural precursors of RA have been proposed. The aim of the present study was to compare the local tolerance profiles of retinol (ROL), retinaldehyde (RAL) and RA...
Antibacterial efficacy of benzoyl peroxide in phospholipid liposomes. A vehicle-controlled, comparative study in patients with papulopustular acneJ W Fluhr
Department of Dermatology, Karlsruhe Municipal Hospital Complex, Karlsruhe, Germany
Dermatology 198:273-7. 1999..Literature reports indicate that phospholipid liposomes facilitate the accumulation of active agents in the infundibulum...
In Vitro activity of 6 antimicrobials against propionibacteria isolates from untreated acne papulopustulosaJ W Fluhr
Hautklinik, Städt Klinikum Karlsruhe, Germany
Zentralbl Bakteriol 289:53-61. 1999..8% of P.acnes and in 0% of the P.granulosum strains. Since sensitivity was seen in 100% of the strains already at a concentration of 16 micrograms/ml, a therapeutic effect may be possible...
Do shake lotions, zinc oil and polyethylene glycol gels produce dehydration or moisturization?M Gloor
Department of Dermatology, Klinikum der Stadt Karlsruhe GmbH, Karlsruhe, Germany
Skin Pharmacol Appl Skin Physiol 14:34-43. 2001..g. in intertriginous regions. Zinc oil and Lotio Cordes can be used in overhydrated skin but not in dry skin, for the missing water-binding capacity in the horny layer. On the other hand an effective dehydrating effect cannot be expected...
Effects of microemulsions on the stratum corneum and hydrocortisone penetrationL Lehmann
Department of Dermatology, Karlsruhe Municipal Medical Center, Moltkestrasse 120, D-76133 Karlsruhe, Germany
Eur J Pharm Biopharm 52:129-36. 2001....
Effects of prolonged occlusion on stratum corneum barrier function and water holding capacityJ W Fluhr
Department of Dermatology, Stadtisches Klinikum Karlsruhe, Germany
Skin Pharmacol Appl Skin Physiol 12:193-8. 1999..We aimed to evaluate whether prolonged occlusion can induce stratum corneum barrier damage, alterations in stratum corneum hydration or water-holding capacity (WHC) lasting longer than the occlusion time...
Direct comparison of skin physiology in children and adults with bioengineering methodsJ W Fluhr
Department of Dermatology, Klinikum Karlsruhe, Karlsruhe, Germany
Pediatr Dermatol 17:436-9. 2000....
Do urea/ammonium lactate combinations achieve better skin protection and hydration than either component alone?M Gloor
Department of Dermatology, Klinikum der Stadt Karlsruhe, Germany
Skin Pharmacol Appl Skin Physiol 15:35-43. 2002..5% urea and both ammonium lactate/urea combinations produced significant stratum corneum hydration and improved stratum corneum barrier function; there were no significant differences between these three treatments...
Cleansing, dehydrating, barrier-damaging and irritating hyperaemising effect of four detergent brands: comparative studies using standardised washing modelsMax Gloor
Dermatology Clinic of the Hospital of the City of Karlsruhe GmbH, Germany
Skin Res Technol 10:1-9. 2004..Furthermore, this experimental approach allowed to differentiate the four tested cleansing solutions...
