Rainer Girgert

Summary

Country: Germany

Publications

  1. ncbi Integrin ?2-deficient mice provide insights into specific functions of collagen receptors in the kidney
    Rainer Girgert
    Department of Nephrology and Rheumatology, Georg August University Goettingen, Goettingen, Germany
    Fibrogenesis Tissue Repair 3:19. 2010
  2. ncbi Exposure of mcf-7 breast cancer cells to electromagnetic fields up-regulates the plasminogen activator system
    Rainer Girgert
    Department of Obstetrics and Gynecology, University of Gottingen, Germany
    Int J Gynecol Cancer 19:334-8. 2009
  3. ncbi Induction of tamoxifen resistance in breast cancer cells by ELF electromagnetic fields
    Rainer Girgert
    Department of Obstetrics and Gynecology, University of Gottingen, Germany
    Biochem Biophys Res Commun 336:1144-9. 2005
  4. ncbi Electromagnetic fields alter the expression of estrogen receptor cofactors in breast cancer cells
    Rainer Girgert
    Department of Gynecology and Obstetrics, University of Gottingen, Gottingen, Germany
    Bioelectromagnetics 29:169-76. 2008
  5. ncbi Signal transduction of the melatonin receptor MT1 is disrupted in breast cancer cells by electromagnetic fields
    Rainer Girgert
    Department of Gynecology and Obstetrics, University of Gottingen, Gottingen, Germany
    Bioelectromagnetics 31:237-45. 2010
  6. ncbi Membrane-bound melatonin receptor MT1 down-regulates estrogen responsive genes in breast cancer cells
    Rainer Girgert
    Department of Obstetrics and Gynecology, University of Gottingen, Gottingen, Germany
    J Pineal Res 47:23-31. 2009
  7. ncbi Loss of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV collagen disease
    Oliver Gross
    Department of Nephrology and Rheumatology, University Medicine Goettingen Robert Koch Strasse 40, Goettingen, Germany
    Matrix Biol 29:346-56. 2010
  8. ncbi Renal protective effects of aliskiren beyond its antihypertensive property in a mouse model of progressive fibrosis
    Oliver Gross
    Department of Nephrology and Rheumatology, University Medicine Goettingen, Germany
    Am J Hypertens 24:355-61. 2011
  9. ncbi Farnesyltransferase inhibitor FTI-277 prevents autocrine growth stimulation of neuroblastoma by BDNF
    Rainer Girgert
    Department of Gynecology and Obstetrics, University of Ulm, Prittwitzstrasse 43, 89075, Ulm, Germany
    J Cancer Res Clin Oncol 129:227-33. 2003
  10. ncbi Tracking the elusive antiestrogenic effect of melatonin: a new methodological approach
    Rainer Girgert
    Dept of Gynecology and Obstetrics, University of Ulm, Prittwitzstrasse 43, D 89075 Ulm, Germany
    Neuro Endocrinol Lett 24:440-4. 2003

Collaborators

Detail Information

Publications12

  1. ncbi Integrin ?2-deficient mice provide insights into specific functions of collagen receptors in the kidney
    Rainer Girgert
    Department of Nephrology and Rheumatology, Georg August University Goettingen, Goettingen, Germany
    Fibrogenesis Tissue Repair 3:19. 2010
    ..The present study evaluates the role of integrin ?2 (ITGA2) in cell-matrix interaction...
  2. ncbi Exposure of mcf-7 breast cancer cells to electromagnetic fields up-regulates the plasminogen activator system
    Rainer Girgert
    Department of Obstetrics and Gynecology, University of Gottingen, Germany
    Int J Gynecol Cancer 19:334-8. 2009
    ..The use of our newly established exposure system for EMFs may allow us to study the signaling processes involved in the induction of a metastatic phenotype of breast cancer cells...
  3. ncbi Induction of tamoxifen resistance in breast cancer cells by ELF electromagnetic fields
    Rainer Girgert
    Department of Obstetrics and Gynecology, University of Gottingen, Germany
    Biochem Biophys Res Commun 336:1144-9. 2005
    ..2muT was observed. Hypothetically, electromagnetic field exposure could contribute to tamoxifen resistance observed in breast cancer after long-term treatment...
  4. ncbi Electromagnetic fields alter the expression of estrogen receptor cofactors in breast cancer cells
    Rainer Girgert
    Department of Gynecology and Obstetrics, University of Gottingen, Gottingen, Germany
    Bioelectromagnetics 29:169-76. 2008
    ..Electromagnetic fields may contribute to the induction of tamoxifen resistance in vivo...
  5. ncbi Signal transduction of the melatonin receptor MT1 is disrupted in breast cancer cells by electromagnetic fields
    Rainer Girgert
    Department of Gynecology and Obstetrics, University of Gottingen, Gottingen, Germany
    Bioelectromagnetics 31:237-45. 2010
    ..These results convincingly prove the negative effect of EMF on the antiestrogenic effect of melatonin in breast cancer cells...
  6. ncbi Membrane-bound melatonin receptor MT1 down-regulates estrogen responsive genes in breast cancer cells
    Rainer Girgert
    Department of Obstetrics and Gynecology, University of Gottingen, Gottingen, Germany
    J Pineal Res 47:23-31. 2009
    ..There was no correlation between the expression of the nuclear receptor RZRalpha and the effects of melatonin on these genes...
  7. ncbi Loss of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV collagen disease
    Oliver Gross
    Department of Nephrology and Rheumatology, University Medicine Goettingen Robert Koch Strasse 40, Goettingen, Germany
    Matrix Biol 29:346-56. 2010
    ..The blockade of collagen-receptor DDR1 might serve as an important new therapeutic concept in progressive fibrotic and inflammatory diseases in the future...
  8. ncbi Renal protective effects of aliskiren beyond its antihypertensive property in a mouse model of progressive fibrosis
    Oliver Gross
    Department of Nephrology and Rheumatology, University Medicine Goettingen, Germany
    Am J Hypertens 24:355-61. 2011
    ..This study investigates the antifibrotic nephroprotective effects of aliskiren in a nonhypertensive mouse model for progressive renal fibrosis...
  9. ncbi Farnesyltransferase inhibitor FTI-277 prevents autocrine growth stimulation of neuroblastoma by BDNF
    Rainer Girgert
    Department of Gynecology and Obstetrics, University of Ulm, Prittwitzstrasse 43, 89075, Ulm, Germany
    J Cancer Res Clin Oncol 129:227-33. 2003
    ..We investigated whether FTI-277 is also active against tumor cells with constitutively activated growth factor receptors but lacking ras-mutations...
  10. ncbi Tracking the elusive antiestrogenic effect of melatonin: a new methodological approach
    Rainer Girgert
    Dept of Gynecology and Obstetrics, University of Ulm, Prittwitzstrasse 43, D 89075 Ulm, Germany
    Neuro Endocrinol Lett 24:440-4. 2003
    ..Detection of the antiestrogenic effect of melatonin on various breast cancer cell lines and its dependence of the differential expression of estrogen receptors (ERalpha and ERbeta) and melatonin receptors (mt1 and RZRalpha)...
  11. ncbi Significance of heparin-binding growth factor expression on cells of solid pediatric tumors
    Winfried Barthlen
    Department of Pediatric Surgery, , , Germany
    J Pediatr Surg 38:1296-304. 2003
    ....
  12. ncbi Induction of N-myc in neuroblastoma by autocrine IGF-II depends on farnesylated Ras. Application of farnesyltransferase inhibitors
    Josefa Wittrock
    Oncological Laboratory, Department of Pediatric Surgery, , Hoppe-Seyler-Strasse 3, , Germany
    Anticancer Res 22:4205-9. 2002
    ..Inactivation of Ras by farnesyltransferase inhibitors might become a promising new approach in future treatments of neuroblastoma tumors...