E WingenderSummaryAffiliation: German Research Centre for Biotechnology Country: Germany Publications
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Detail Information
Publications
The TRANSFAC system on gene expression regulationE Wingender
Gesellschaft fur Biotechnologische Forschung mbH, Mascheroder Weg 1, D 38124 Braunschweig, Germany
Nucleic Acids Res 29:281-3. 2001..They are accompanied by a number of program routines for identifying potential transcription factor binding sites or for localizing individual components in the regulatory network of a cell...
TRANSFAC: an integrated system for gene expression regulationE Wingender
Gesellschaft fur Biotechnologische Forschung mbH, Mascheroder Weg 1, D 38124 Braunschweig, Germany
Nucleic Acids Res 28:316-9. 2000..Additionally, the databases TRANSPATH, about signal transduction, and CYTOMER, about organs and cell types, have been extended and are increasingly integrated with the TRANSFAC data sources...
TRANSFAC, TRRD and COMPEL: towards a federated database system on transcriptional regulationE Wingender
Gesellschaft fur Biotechnologische Forschung mbH, Mascheroder Weg 1, D 38124 Braunschweig, Germany
Nucleic Acids Res 25:265-8. 1997..COMPEL comprises specific information on composite regulatory elements. Here, we describe the present status of these databases and the first steps towards their federation...
Evaluation of sequence motifs found in scaffold/matrix-attached regions (S/MARs)I Liebich
Research Group Bioinformatics, Gesellschaft fur Biotechnologische Forschung mbH, Mascheroder Weg 1, D 38124 Braunschweig, Germany
Nucleic Acids Res 30:3433-42. 2002..Our results can serve as a guideline for further improvements in the definition of S/MARs, which are now believed to constitute the functional coordinate system for genomic regulatory regions...
MATCH: A tool for searching transcription factor binding sites in DNA sequencesA E Kel
BIOBASE GmbH, Halchtersche Str 33, D 38304 Wolfenbuttel, Germany
Nucleic Acids Res 31:3576-9. 2003..com/pub/programs.html#match. The same program with a different web interface can be found at http://compel.bionet.nsc.ru/Match/Match.html. An advanced version of the tool called Match Professional is available at http://www.biobase.de...
Composite Module Analyst: identification of transcription factor binding site combinations using genetic algorithmT Waleev
A.P. Ershov's Institute of Informatics Systems 6, Lavrentiev Avenue, 630090 Novosibirsk, Russia
Nucleic Acids Res 34:W541-5. 2006..gene-regulation.com/pub/programs/cma/CMA.html. An advanced version of CMA is also a part of the commercial system ExPlaintrade mark (www.biobase.de) designed for causal analysis of gene expression data...
TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotesV Matys
BIOBASE GmbH, Halchtersche Strasse 33, D 38304 Wolfenbuttel, Germany
Nucleic Acids Res 34:D108-10. 2006..The here described public releases, TRANSFAC 7.0 and TRANSCompel 7.0, are accessible under http://www.gene-regulation.com/pub/databases.html...
Recognition of multiple patterns in unaligned sets of sequences: comparison of kernel clustering method with other methodsA Kel
Institute of Cytology and Genetics SB RAN, Lavrentyev pr, 10, 630090, Novosibirsk, Russia
Bioinformatics 20:1512-6. 2004..Often one set of sites can contain several subsets of sequences that follow not just one but several different patterns. There is a need for sensitive methods to reveal multiple patterns in unaligned sets of sequences...
Composite Module Analyst: a fitness-based tool for identification of transcription factor binding site combinationsA Kel
BIOBASE GmbH Halchtersche Str 33, D 38304 Wolfenbuttel, Germany
Bioinformatics 22:1190-7. 2006..Cis-element combinations provide a structural basis for the generation of unique patterns of gene expression...
The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resourcesT Crass
Department of Bioinformatics, Medical Faculty, Georg August University Gottingen, Goldschmidtstrasse 1, 37077 Gottingen, Germany
Bioinformatics 20:268-70. 2004..Currently, automated cascades for the analysis of regulatory DNA segments as well as for the prediction of protein functional properties are provided. AVAILABILITY: The HNB portal is available at http://www.hnbioinfo.de..
TRANSFAC: transcriptional regulation, from patterns to profilesV Matys
BIOBASE GmbH, Halchtersche Strasse 33, D 38304 Wolfenbuttel, Germany
Nucleic Acids Res 31:374-8. 2003..gbf.de. For CYTOMER free download versions are available at http://www.biobase.de:8080/index.html...
Structure of the gene encoding the rat T cell ecto-ADP-ribosyltransferase RT6F A Haag
Department of Immunology, University Hospital Hamburg Eppendorf, Germany
J Immunol 157:2022-30. 1996..Analysis of RT6 transcripts showed that this promoter is the major one in adult rat spleen cells. The 3' end of the gene does not display alternative splicing. However, two polyadenylation signals are found in the 3' untranslated region...
Organization and sequence of the gene encoding the human acrosin-trypsin inhibitor (HUSI-II)A Moritz
Department of Clinical Chemistry and Clinical Biochemistry, University of Munich, Germany
Gene 123:277-81. 1993..The localization of the gene to chromosome 4 was determined by hybridization of a 5' genomic fragment to the DNA of a panel of somatic hybrids between human and rodent cells...
Purification of human transcription factor IIIA and its interaction with a chemically synthesized gene encoding human 5 S rRNAK H Seifart
Institut fur Molekularbiologie and Tumorforschung, Marburg Lahnberge, Federal Republic of Germany
J Biol Chem 264:1702-9. 1989..These results, together with the difference in molecular mass of these functionally analogous proteins, reemphasize the importance of homologous systems for the analysis of mechanisms involved in gene regulation...
