Research Topics
| Markus GaubitzSummaryCountry: Germany Publications
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Detail Information
Publications
Mycophenolate mofetil for the treatment of systemic lupus erythematosus: an open pilot trialM Gaubitz
Department of Medicine B, University of Munster, Munster, Germany
Lupus 8:731-6. 1999..To investigate the effectiveness and safety of mycophenolate mofetil in patients with systemic lupus erythematosus who were inadequately controlled with corticosteroids, antimalarials, and other immunosuppressive agents...- Epidemiology of connective tissue disordersM Gaubitz
Department of Medicine B, Munster University Hospital, Munster, Germany
Rheumatology (Oxford) 45:iii3-4. 2006.... - [Early diagnosis in patients with systemic lupus erythematosus (SLE)]M Gaubitz
Medizinische Klinik und Poliklinik B, Universitatsklinikum Munster, Domagkstrasse 3a, 48149 Munster, Germany
Z Rheumatol 64:547-52. 2005..With respect to the potentially life or organ threatening course of SLE a good interdisciplinary cooperation of general practitioners and specialists with rheumatologists is of special importance... - Differentiation of RNP- and SM-antibody subsets in SLE and MCTD patients by a new ELISA using recombinant antigensMarkus Gaubitz
Department of Medicine B, University of Munster, Germany
Cell Mol Biol (Noisy-le-grand) 48:317-21. 2002..In SLE and MCTD, determination of subsets of antibodies against Ul-snRNP-68 kDa and Sm-complex allows a differentiation of patient subgroups with more definite diagnoses and potential prognostic impact... - Cogan's syndrome: organ-specific autoimmune disease or systemic vasculitis? A report of two cases and review of the literatureM Gaubitz
Department of Medicine B, University of Munster, Germany
Clin Exp Rheumatol 19:463-9. 2001..We then review the typical aspects as well as the etiology of the disease... - Cat scratch disease (bartonellosis) mimicking an SLE flareM Gaubitz
Department of Medicine, University of Munster, Germany
Lupus 10:883-5. 2001..This tentative diagnosis was confirmed serologically. Under clarithromycin treatment the patient rapidly responded and her temperature dropped within 2 days... - Increased serum levels of macrophage migration inhibitory factor in patients with primary Sjögren's syndromePeter Willeke
Department of Medicine B, Muenster University Hospital, Albert Schweitzer Strasse 33, 48129 Muenster, Germany
Arthritis Res Ther 9:R43. 2007..MIF may contribute to B-cell hyperactivity indicated by hypergammaglobulinemia. The inverse relationship of IL-10 and MIF suggests that IL-10 works as an antagonist of MIF in pSS... - Mycophenolate sodium treatment in patients with primary Sjögren syndrome: a pilot trialPeter Willeke
Department of Medicine B, Muenster University Hospital, Albert Schweitzer Street 33, D 48129 Muenster, Germany
Arthritis Res Ther 9:R115. 2007..Further investigations about the efficacy and safety of MPS in pSS have to be performed in larger numbers of patients... - Interferon-gamma is increased in patients with primary Sjogren's syndrome and Raynaud's phenomenonPeter Willeke
Department of Medicine B, Muenster University Hospital, Muenster, Germany
Semin Arthritis Rheum 39:197-202. 2009..Since increased interferon-gamma (INF-gamma) has been associated with RP, we also compared the INF-gamma production in pSS patients with or without RP... - Clinical utility of the anti-CCP assay: experiences with 700 patientsUlrich Sauerland
Department of Medicine B, , Albert-Schweitzer-Strasse 33, , Germany
Ann N Y Acad Sci 1050:314-8. 2005..Anti-CCP also helps to diagnose other inflammatory and noninflammatory diseases (especially connective tissue diseases) by reducing the rate of false-positive results in comparison with RF... - Macrophage migration inhibitory factor may contribute to vasculopathy in systemic sclerosisHeidemarie Becker
Department of Medicine B, University of Muenster, Albert Schweitzer Str 33, 48129, Muenster, Germany
Clin Rheumatol 27:1307-11. 2008..MIF levels were not significantly different in patients with and without macrovascular disease of the peripheral arteries. The results suggest that MIF might contribute to inflammation and vasculopathy in SSc... - Development of an in vitro miniature model to simulate immunoadsorption in patients with systemic lupus erythematosusBirgit Avenhaus
Department of Medicine B, University of Muenster, Muenster, Germany
J Clin Apher 17:183-9. 2002..This in vitro minimodel provides a precise simulation of therapeutic immunoadsorption and helps to analyze the binding characteristics of the sorbent IMPH and shows its effectiveness in several antibody subsets of different patients... - Relationship between serum levels of macrophage migration inhibitory factor and the activity of antineutrophil cytoplasmic antibody-associated vasculitidesHeidemarie Becker
Department of Medicine B, University of Muenster, Albert Schweitzer Strasse 33, 48129 Munster, Germany
Clin Rheumatol 25:368-72. 2006..The results suggest that MIF contributes to the inflammatory process and correlates with disease activity in antineutrophil cytoplasmic antibody-associated vasculitides... - Altered brain activity during pain processing in fibromyalgiaMarkus Burgmer
Department of Psychosomatics and Psychotherapy, University Hospital Munster, Munster, Germany
Neuroimage 44:502-8. 2009.... - Decreased gray matter volumes in the cingulo-frontal cortex and the amygdala in patients with fibromyalgiaMarkus Burgmer
Department of Psychosomatics and Psychotherapy, University Hospital Munster, Domagkstr 22, 48153 Münster, Germany
Psychosom Med 71:566-73. 2009..To determine whether structural changes in areas of the pain system are additional preconditions for the central sensitization in fibromyalgia we performed voxel based morphometry in patients with fibromyalgia and healthy controls... - Fibromyalgia unique temporal brain activation during experimental pain: a controlled fMRI StudyMarkus Burgmer
Department of Psychosomatics and Psychotherapy, University Hospital Munster, Munster, Germany
J Neural Transm 117:123-31. 2010..Our results support the hypothesis that central mechanisms of pain processing in the frontal cortex and cingulate cortex may play an important role in patients with FMS... - Fracture of the odontoid process complicating tardive dystoniaCarsten Konrad
Department of Neurology, Department of Psychiatry, University of Muenster, Germany
Mov Disord 19:983-5. 2004..Neurologists with a focus on movement disorders should screen for diseases putting the patient at risk for spinal lesions and consider early treatment... - Ischaemic colitis mimicking inflammatory bowel disease in a young adult receiving oral anticoagulationPeter Willeke
Department of Medicine B, Muenster University Hospital, Germany
Scand J Gastroenterol 40:878-80. 2005..We present a case of a young man with known factor-V-Leiden mutation in whom IC developed during effective therapy with oral anticoagulants, presenting with symptoms and endoscopic findings suggestive of inflammatory bowel disease... - Concomitant reduction of disease activity and IL-10 secreting peripheral blood mononuclear cells during immunoadsorption in patients with active systenic lupus erythematosusPeter Willeke
Department of Medicine B, Westphalian Wilhelms University, Munster, Germany
Cell Mol Biol (Noisy-le-grand) 48:323-9. 2002..The production of anti-ds-DNA antibodies and IL-10 are interdependent. Thus we conclude that IA is beneficial in SLE by depletion of these pathogenic antibodies which may lead to a reduced IL-10 secretion in vivo... - Gastrointestinal bleeding secondary to hepatic artery involvement of microscopic polyangiitis: case report and review of the literatureThomas W Spahn
Department of Medicine B, Muenster University Hospital, Muenster, Germany
Dig Dis Sci 52:1558-61. 2007 - Topical tacrolimus as a therapeutic adjunct in patients with cutaneous lupus erythematosus. A report of three casesMarkus Bohm
Department of Dermatology, University of Munster, Munster, Germany
Dermatology 207:381-5. 2003..Treatment with topical tacrolimus was tolerated well without major side effects in all patients. The presented cases are in line with recent reports that topical tacrolimus may be effective in facial LE... - Immunoadsorption in systemic lupus erythematosus: different techniques and their current role in medical therapyMarkus Gaubitz
Medical Clinic B, Westphalian Wilhelms-University, , Germany
Ther Apher Dial 7:183-8. 2003..Randomized controlled trials are mandatory to give continued support to the therapeutic opportunities offered only by immunoadsorption; the limited number of patients suitable for this therapy necessitates multicentric cooperation...