Research Topics
| Karsten KrakowSummaryAffiliation: Frankfurt am Main Country: Germany Publications
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Detail Information
Publications
Imaging epileptic activity using functional MRIKarsten Krakow
Department of Neurology, J W Goethe University, and Brain Imaging Center, Frankfurt, Germany
Neurodegener Dis 5:286-95. 2008..e. the irritative zone. In patients with generalizes IED, suspension of functional networks due to the IED can be demonstrated. The utility of EEG-correlated fMRI in clinical epileptology cannot be definitely determined yet...
Recovery of visual field constriction following discontinuation of vigabatrinK Krakow
Epilepsy Research Group, Department of Clinical Neurology, Institute of Neurology, University College London, Queen Square, London, UK
Seizure 9:287-90. 2000..Larger scale clinical studies are needed to identify predictive factors both for the occurrence and reversibility of vigabatrin-associated visual field defects...
Fixation-off sensitivity as a model of continuous epileptiform discharges: electroencephalographic, neuropsychological and functional MRI findingsK Krakow
Epilepsy Research Group, Department of Clinical Neurology, Institute of Neurology, University College London, London, UK
Epilepsy Res 42:1-6. 2000..This localization was confirmed with 64-channel EEG source analysis. The applied methods provided additional information on the pathophysiology of epileptiform discharges...
Long-term continuation of levetiracetam in patients with refractory epilepsyK Krakow
Epilepsy Research Group, Department of Clinical Neurology, Institute of Neurology, University College London, UK
Neurology 56:1772-4. 2001..Thirty-nine percent (512/1,325) of patients had a seizure reduction of > or =50%, and 13% (183/1,422) became seizure-free for at least 6 months. LEV seems an effective and well tolerated new antiepileptic drug...
fMRI correlates of interictal epileptic activity in patients with idiopathic benign focal epilepsy of childhood. A simultaneous EEG-functional MRI studyUlrike Lengler
Department of Neurology, Johann Wolfgang Goethe University and Brain Imaging Center, Frankfurt Main, Germany
Epilepsy Res 75:29-38. 2007..Further studies are required to differentiate between BFE subtypes and to identify fMRI signatures of specific syndromes or corresponding neuropsychological deficits...
Arousal thresholds during human tonic and phasic REM sleepUmmehan Ermis
Department of Neurology, Goethe Universitat Frankfurt, Germany
J Sleep Res 19:400-6. 2010..Ocular activity such as ponto-geniculo-occipital-like waves and microsaccades are discussed as likely modulators of behavioural responsiveness and cortical processing of auditory information in the two REM sub-states...
Effects of antiepileptic drugs on associative LTP-like plasticity in human motor cortexTonio Heidegger
Department of Neurology, Goethe University of Frankfurt, Schleusenweg 2 16, D 60528 Frankfurt am Main, Germany
Eur J Neurosci 32:1215-22. 2010..The particular depressant effect of levetiracetam on LTP-like plasticity may also relate to the unique properties of this drug to inhibit epileptogenesis, a potentially LTP-associated process...
Linking generalized spike-and-wave discharges and resting state brain activity by using EEG/fMRI in a patient with absence seizuresHelmut Laufs
Department of Neurology, Johann Wolfgang Goethe University and Brain Imaging Center Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany
Epilepsia 47:444-8. 2006....
Depersonalization and social anxietyMatthias Michal
Clinic for Psychosomatic Medicine and Psychotherapy, University Frankfurt am Main, Germany
J Nerv Ment Dis 193:629-32. 2005..The association of social anxiety with DP merits further research. A general consideration of DP in clinical and neurobiological trials on anxiety disorders like social phobia is warranted...
Sleep improvement in an insomniac patient with global pituitary insufficiency after change from triple to quadruple cortisol replacement therapyUrsula Voss
Department of Psychology, J W Goethe University Frankfurt M, Germany
Sleep Med 8:517-9. 2007..Clinically, the data are suggestive of the need to assimilate HRT to the natural circadian cortisol rhythm and not restrict it to the active part of the day...
Spontaneous dissociation during functional MRI experimentsMatthias Michal
Clinic for Psychosomatic Medicine and Psychotherapy, University Frankfurt M, Heinrich Hoffmann Street 10, 60528 Frankfurt am Main, Germany
J Psychiatr Res 41:69-73. 2007..Further studies on the actual phenomenological experience of subjects undergoing fMRI procedures are warranted...
Intraoperative ultrasound to define focal cortical dysplasia in epilepsy surgeryDorothea Miller
Department of Neurosurgery, Philipps University Marburg, Germany
Epilepsia 49:156-8. 2008..Postoperatively the patient remained seizure free. Intraoperative ultrasound may be helpful in identifying and targeting subtle epileptogenic lesions, which are difficult to visualize...
The nature of MR signal changesLouis Lemieux
Radiology 226:922-3; author reply 923-5. 2003
Levetiracetam intravenous infusion as an alternative to oral dosing in patients with partial-onset seizuresMichel Baulac
Hopital de la Pitie Salpetriere, Service de Neurologie 1, Paris, France
Epilepsia 48:589-92. 2007..This multicenter, open-label study evaluated the short-term tolerability of intravenously (IV)-infused levetiracetam (LEV; 500-1,500 mg/100 ml, 15 min, b.i.d.) as a substitute for the same oral dose...
