Research Topics
| Nikolaus KleindienstSummaryAffiliation: Central Institute of Mental Health Country: Germany Publications
| Collaborators
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Detail Information
Publications
Syndromes and phenomenological subtypes underlying acute mania: a factor analytic study of 576 manic patientsTetsuya Sato
Psychiatrische Klinik der Ludwig Maximilians Universität, Munchen, Germany
Am J Psychiatry 159:968-74. 2002..There is controversy as to whether atypical manic features such as aggression, psychosis, and depression are likely to coexist among manic patients. The authors' goal was to examine this controversy...
Motives for nonsuicidal self-injury among women with borderline personality disorderNikolaus Kleindienst
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
J Nerv Ment Dis 196:230-6. 2008..NSSI was usually preceded by a large variety of negative feelings that were reported to clearly improve with NSSI. In conclusion, therapists should anticipate a multidimensional functional spectrum when exploring motives of NSSI...
Dissociation predicts poor response to Dialectial Behavioral Therapy in female patients with Borderline Personality DisorderNikolaus Kleindienst
Central Institute of Mental Health, Mannheim, Germany
J Pers Disord 25:432-47. 2011..The results suggest that dissociation in borderline-patients should be closely monitored and targeted during DBT. At this stage, research on treatment of dissociation (e.g., specific skills training) is warranted...
Are serum lithium levels related to the polarity of recurrence in bipolar disorders? Evidence from a multicenter trialNikolaus Kleindienst
Department of Psychiatry, University of Munich, Munich, Germany
Int Clin Psychopharmacol 22:125-31. 2007..If substantiated by further studies, this finding might indicate that higher lithium levels are needed to prevent manic episodes than to prevent depressive episodes...
Emotional learning during dissociative states in borderline personality disorderUlrich W Ebner-Priemer
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, University of Heidelberg, Germany
J Psychiatry Neurosci 34:214-22. 2009..The aim of our study was to determine whether high states of dissociative experience would specifically alter emotional learning, but not declarative knowledge...
Do improvements after inpatient dialectial behavioral therapy persist in the long term? A naturalistic follow-up in patients with borderline personality disorderNikolaus Kleindienst
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
J Nerv Ment Dis 196:847-51. 2008..The effects of inpatient dialectical behavior therapy seem to persist after patients returned to their usual lives...
The short version of the Borderline Symptom List (BSL-23): development and initial data on psychometric propertiesMartin Bohus
Department of Psychosomatics and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
Psychopathology 42:32-9. 2009..The BSL-95 includes 95 items. In order to reduce patient burden and assessment time, a short version with 23 items (BSL-23) was developed...
Distress and affective dysregulation in patients with borderline personality disorder: a psychophysiological ambulatory monitoring studyUlrich W Ebner-Priemer
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, 68072 Mannheim, Germany
J Nerv Ment Dis 196:314-20. 2008..Physiological arousal (heart rate) was related to distress in both groups. Our empirical findings emphasize training in labeling emotions and distress tolerance interventions in treatment for BPD...
Pain sensitivity is reduced in borderline personality disorder, but not in posttraumatic stress disorder and bulimia nervosaChristian Schmahl
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
World J Biol Psychiatry 11:364-71. 2010..To establish whether these findings are specific for BPD, we compared pain thresholds in patients with BPD, posttraumatic stress disorder (PTSD), bulimia nervosa, and healthy controls...
Dialectical behavior therapy for posttraumatic stress disorder related to childhood sexual abuse: a pilot study of an intensive residential treatment programRegina Steil
Central Institute of Mental Health, Mannheim, Germany
J Trauma Stress 24:102-6. 2011..An effect size of 1.22 on the PDS was found between baseline and follow-up. Effect sizes for secondary outcomes ranged from medium to large. The results suggest that DBT-PTSD has promise for reducing severe and chronic PTSD after CSA...
Hippocampus and amygdala volumes in patients with borderline personality disorder with or without posttraumatic stress disorderChristian Schmahl
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
J Psychiatry Neurosci 34:289-95. 2009..Both groups exhibit volume reductions of the hippocampus and amygdala. Our aim was to investigate the influence of comorbid PTSD on hippocampus and amygdala volumes in patients with BPD...
Evaluation of a DVD-based self-help program in highly socially anxious individuals--pilot studyAnna K Mall
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
Behav Ther 42:439-48. 2011..24 to 0.65 in favor of the active intervention. The newly developed DVD-based self-help program seems to be a promising intervention for highly socially anxious individuals as it reduces social anxiety symptoms...
Evaluation of naltrexone for dissociative symptoms in borderline personality disorderChristian Schmahl
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
Int Clin Psychopharmacol 27:61-8. 2012..However, the effects were too small to reach statistical significance. Our data provide the first estimate of the pure pharmacological antidissociative efficacy of naltrexone from a rigorously designed trial...
State affective instability in borderline personality disorder assessed by ambulatory monitoringUlrich W Ebner-Priemer
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, University of Heidelberg, Germany
Psychol Med 37:961-70. 2007..Furthermore, the pattern of instability that characterizes BPD has not yet been identified...
Is the prophylactic antidepressant efficacy of lithium in bipolar I disorder dependent on study design and lithium level?Wolfram Emanuel Severus
Department of Psychiatry, University of Munich, Germany
J Clin Psychopharmacol 25:457-62. 2005..In these trials, factors previously associated with predicting response to lithium should also be assessed...
Effects of risperidone and quetiapine on cognition in patients with schizophrenia and predominantly negative symptomsMichael Riedel
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University of Munich, Nussbaumstrasse 7, 80336, Munich, Germany
Eur Arch Psychiatry Clin Neurosci 257:360-70. 2007..Also, the improvements in cognition following treatment with quetiapine and risperidone may enhance long-term outcomes for these patients...
Analytic strategies for understanding affective (in)stability and other dynamic processes in psychopathologyUlrich W Ebner-Priemer
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany
J Abnorm Psychol 118:195-202. 2009..For the assessment of unstable interpersonal relationships, they advocate the use of event-contingent recordings and separate analyses within and across dyads...
Effects of a partly self-administered exercise program before, during, and after allogeneic stem cell transplantationJoachim Wiskemann
Central Institute of Mental Health, Mannheim, Germany
Blood 117:2604-13. 2011..In conclusion, this partly supervised exercise intervention is beneficial for patients undergoing allo-HSCT. Because of low personnel requirements, it might be valuable to integrate such a program into standard medical care...
Mixed depressive features predict maniform switch during treatment of depression in bipolar I disorderRonald Bottlender
Department of Psychiatry, Ludwig-Maximilians University, Munich, Germany
J Affect Disord 78:149-52. 2004..Further validation studies on mixed depression are warranted...
Are illness concepts a powerful predictor of adherence to prophylactic treatment in bipolar disorder?Nikolaus Kleindienst
Psychiatric Hospital of the University of Munich, Germany
J Clin Psychiatry 65:966-74. 2004..The present study is the first to prospectively investigate the influence of illness concepts on adherence of bipolar patients to different medications...
Evaluating the inter-episode stability of depressive mixed statesTetsuya Sato
Psychiatric Hospital, Ludwig Maximilian University LMU, Nussbaumstr 7, D 80336 Munich, Germany
J Affect Disord 81:103-13. 2004..Our goal was to provide preliminary evidence of the inter-episode stability of DMX. The inter-episode stability is known to be an important validator for establishing a distinct clinical entity...
Re-evaluation of randomized controlled trials of lithium monotherapyW Emanuel Severus
Bipolar Disord 8:519-20; author reply 521. 2006
Attention-deficit hyperactivity disorder as a potentially aggravating factor in borderline personality disorderAlexandra Philipsen
Department of Psychiatry and Psychotherapy, University Medical Center, Freiburg, Germany
Br J Psychiatry 192:118-23. 2008..Clinical experience suggests that people with borderline personality disorder often meet criteria for attention-deficit hyperactivity disorder (ADHD). However, empirical data are sparse...
