Research Topics
| Jorg BrederlauSummaryCountry: Germany Publications
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Detail Information
Publications
Liver dysfunction after lung recruitment manoeuvres during pressure-controlled ventilation in experimental acute respiratory distressMarkus Kredel
University of Wurzburg, Department of Anaesthesiology, University Hospital Wurzburg, Wurzburg, Germany
Crit Care 11:R13. 2007..We therefore investigated liver dysfunction during two different ventilation treatment regimens of experimental acute respiratory distress syndrome...
Arteriovenous extracorporeal lung assist allows for maximization of oscillatory frequencies: a large-animal model of respiratory distressRalf M Muellenbach
University of Wuerzburg, Department of Anaesthesiology University hospital Wuerzburg Oberduerrbacherstr, 6 97080 Wuerzburg, Germany
BMC Anesthesiol 8:7. 2008....
Comparison of arterial and central venous cannulations using ultrasound guidance in pigsJoerg Brederlau
Department of Anaesthesiology, Wuerzburg University Hospital, Wuerzburg, Germany
Vet Anaesth Analg 35:161-5. 2008..To evaluate the feasibility of ultrasound guided vascular access in pigs by comparing central venous and arterial cannulation techniques...
Combination of arteriovenous extracorporeal lung assist and high-frequency oscillatory ventilation in a porcine model of lavage-induced acute lung injury: a randomized controlled trialJoerg Brederlau
Klinik und Poliklinik für Anästhesiologie, Universitatsklinikum Wurzburg, Wurzburg, Germany
J Trauma 62:336-46; discussion 345-6. 2007....
The contribution of arterio-venous extracorporeal lung assist to gas exchange in a porcine model of lavage-induced acute lung injuryJorg Brederlau
Department of Anaesthesiology, Würzburg University Hospital, Wurzburg, Germany
Perfusion 21:277-84. 2006..AV-ECLA's contribution to oxygenation during severe hypoxemia was antagonized by a significant increase in the pulmonary shunt fraction...
[Transesophageal echocardiography for non-cardiac surgery patients: superfluous luxury or essential diagnostic tool?]J Brederlau
Klinik und Poliklinik für Anästhesiologie, Zentrum Operative Medizin, Universitatsklinikum Wurzburg, and Klinik für Anästhesie und Operative Intensivmedizin, St Franziskus Hospital, Munster
Anaesthesist 55:937-40, 942-3. 2006..The value of transesophageal echocardiography (TEE) in non-cardiac critically ill patients has barely been studied...
Arteriovenous extracorporeal lung assist and high frequency oscillatory ventilation in post-traumatic acute respiratory distress syndromeJoerg Brederlau
Universitaetsklinikum Wuerzburg, Wuerzburg, Germany
J Trauma 64:E65-8. 2008
Pumpless extracorporeal lung assist in severe blunt chest traumaJoerg Brederlau
Department of Anaesthesiology adn Critical Care, Wuerzburg University Hospital, Wuerzburg, Germany
J Cardiothorac Vasc Anesth 18:777-9. 2004
Ultrasound-guided cannulation of the internal jugular vein in critically ill patients positioned in 30 degrees dorsal elevationJ Brederlau
Universitatsklinikum Wurzburg, Klinik und Poliklinik für Anästhesiologie, Wurzburg, Germany
Eur J Anaesthesiol 21:684-7. 2004..The objective of this study was to assess the safety of real-time ultrasound-guided catheterization of the internal jugular vein in ventilated patients with the patient positioned in a 30 degrees head-up position...
[The present role of interventional lung assist (ILA) in critical care medicine]J Brederlau
Klinik und Poliklinik für Anästhesiologie, Zentrum Operative Medizin, Universitatsklinikum Wurzburg, Wurzburg
Anasthesiol Intensivmed Notfallmed Schmerzther 40:74-8. 2005..Pumpless arteriovenous interventional lung assist systems (ILA) can be used in a subgroup of patients with ARDS. ILA might be indicated in earlier stages of ARDS following a multimodal treatment approach...
High-frequency oscillation combined with arteriovenous extracorporeal lung assist reduces lung injuryRalf M Muellenbach
Department of Anesthesiology, University of Wurzburg, Wurzburg, Germany
Exp Lung Res 36:148-58. 2010..Thus, combination of HFOV and av-ECLA might be a further lung-protective tool if conventional ventilation strategies are failing...
Combining "open-lung" ventilation and arteriovenous extracorporeal lung assist: influence of different tidal volumes on gas exchange in experimental lung failureRalf M Muellenbach
Department of Anesthesia and Critical Care, University of Wuerzburg, Wuerzburg, Germany
Med Sci Monit 15:BR213-20. 2009....
Pulmonary effects of positive end-expiratory pressure and fluid therapy in experimental lung injuryMarkus Kredel
Department of Anaesthesia and Critical Care, University of Wurzburg, Wurzburg, Germany
Exp Lung Res 37:35-43. 2011..9 (0.8-1.4) (P < .05). In lavage-induced lung injury, high PEEP improved oxygenation, but restrictive volume administration markedly reduced the lung injury score, mainly by reduced edema...
Whole-body multislice computed tomography as the first line diagnostic tool in patients with multiple injuries: the focus on timeThomas Erik Wurmb
Department of Anesthesiology, University Hospital Wuerzburg, Wuerzburg, Germany
J Trauma 66:658-65. 2009....
High-frequency oscillatory ventilation reduces lung inflammation: a large-animal 24-h model of respiratory distressRalf M Muellenbach
Department of Anaesthesiology, University of Wuerzburg, Oberduerrbacher Strasse 6, 97080 Wuerzburg, Germany
Intensive Care Med 33:1423-33. 2007..The aim of this study was to compare gas exchange, lung histopathology and inflammatory cytokine expression during lung-protective pressure-controlled ventilation (PCV) and HFOV in a long-term large-animal model of ARDS...
Application of standard operating procedures accelerates the process of trauma care in patients with multiple injuriesThomas Erik Wurmb
Department of Anaesthesiology, University Hospital of Wuerzburg, Wuerzburg, Germany
Eur J Emerg Med 15:311-7. 2008..Objective of this study is to determine whether the formulation of standard operating procedures (SOPs) and their incorporation in a trauma pathway are associated with an improvement of trauma treatment process...
[The DGAI training module 2 in anaesthetic focussed sonography: vascular sonography]Herbert Trautner
Klinik und Poliklinik für Anästhesiologie, Universitatsklinikum Wurzburg
Anasthesiol Intensivmed Notfallmed Schmerzther 46:756-9. 2011..The confident use of ultrasound in vascular puncture sharpens our dedicated professional competence and will contribute to continuously improve the quality and safety of anaesthesiologic patient care...
Whole-body multislice computed tomography as the primary and sole diagnostic tool in patients with blunt trauma: searching for its appropriate indicationThomas Erik Wurmb
Klinik und Poliklinik für Anästhesiologie der Universität Würzburg, 97080 Wurzburg, Germany
Am J Emerg Med 25:1057-62. 2007..Until we know more about the most relevant and independent predictive factors, sole reliance upon multislice computed tomography in triaging suspected polytrauma victims will imply the risk to overscan many patients...
[Which perioperative tidal volume for patients with healthy lungs undergoing elective surgery? A qualitative systematic review of current evidence]Julian Kuestermann
Klinik und Poliklinik für Anästhesiologie, Universitätsklinikum Würzburg und Mitarbeiter der Arbeitsgruppe Akutes Lungen versagen
Anasthesiol Intensivmed Notfallmed Schmerzther 44:404-11. 2009..But what tidal volume is the best for the patient with non-injured lungs undergoing elective surgery?..
Acute respiratory distress induced by repeated saline lavage provides stable experimental conditions for 24 hours in pigsRalf M Muellenbach
Department of Anesthesiology, University of Wuerzburg, Germany muellenbac
Exp Lung Res 35:222-33. 2009..01). The presented surfactant depletion-based lung injury model was associated with increased pulmonary inflammation and fulfilled the criteria of acute ling injury (ALI) for 24 hours...
Early treatment with arteriovenous extracorporeal lung assist and high-frequency oscillatory ventilation in a case of severe acute respiratory distress syndromeR M Muellenbach
Department of Anaesthesiology, University of Wuerzburg, Wuerzburg, Germany
Acta Anaesthesiol Scand 51:766-9. 2007..High-frequency oscillatory ventilation (HFOV) is an alternative form of ventilation that may improve oxygenation while limiting the risk of further lung injury by using extremely small tidal volumes (VT)...
Whole-body multislice computed tomography (MSCT) improves trauma care in patients requiring surgery after multiple traumaT E Wurmb
Department of Anaesthesiology, University Hospital of Wuerzburg, Oberdürrbacherstrasse 6, 97080 Wurzburg, Germany
Emerg Med J 28:300-4. 2011..The second goal of the study was to investigate whether the diagnostic approach chosen has an impact on outcome...
Ultrasound-guided anaesthesia of the axillary brachial plexus: efficacy of multiple injection approachU Schwemmer
Department of Anaesthesiology, University Hospital Wurzburg, Germany
Ultraschall Med 26:114-9. 2005..The visualisation of nerves can improve the quality of nerve blocks. The aim of our study was to investigate the feasibility of hand held ultrasound to perform sonographically guided blockades of the axillary plexus...
Hepatic effects of an open lung strategy and cardiac output restoration in an experimental lung injuryM Kredel
Department of Anaesthesia and Critical Care, University of Wurzburg, Oberdürrbacherstrasse 6, 97080 Wurzburg, Germany
Acta Anaesthesiol Scand 54:632-42. 2010..We hypothesized that an open lung concept (OLC) using high PEEP impairs liver function and integrity dependent on the stabilization of cardiac output...
[The Würzburg polytrauma algorithm. Concept and first results of a sliding-gantry-based computer tomography diagnostic system]T Wurmb
Klinik und Poliklinik für Anästhesiologie, Universitat Wurzburg
Anaesthesist 54:763-8; 770-2. 2005....
[Management of seriously injured patients without conventional radiography? Does a whole body MSCT scanner replace the conventional X-ray unit in the emergency room?]T Wurmb
Klinik und Poliklinik für Anästhesiologie, Universitat, Wurzburg
Anaesthesist 55:17-25. 2006..A conventional X-ray unit is not available directly in the resuscitation room of the trauma suite. Three cases are reported to discuss whether state-of-the-art trauma management can be done without conventional radiography...
Handheld vs. conventional transesophageal echocardiography in non-cardiac surgical intensive care unit patientsC Schneider
Klinik und Poliklinik für Anästhesiologie, Universitatsklinikum Wurzburg, Germany
Ultraschall Med 29:531-4. 2008..We examined the feasibility of a newly developed handheld ultrasound device capable of transesophageal echocardiography (TEE)...
[Polytrauma management in a period of change: time analysis of new strategies for emergency room treatment]T Wurmb
Klinik und Poliklinik für Anästhesiologie, Zentrum Operative Medizin, Universitatsklinikum Wurzburg, Oberdürrbacherstrasse 6, Wurzburg, Germany
Unfallchirurg 112:390-9. 2009..The aim of this study was to evaluate both components with respect to the time factor for treatment...
[Ultrasound guidance in regional anesthesia]U Schwemmer
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Anasthesiol Intensivmed Notfallmed Schmerzther 41:260-2. 2006
Arteriovenous extracorporeal lung assist as integral part of a multimodal treatment concept: a retrospective analysis of 22 patients with ARDS refractory to standard careR M Muellenbach
University of Wuerzburg, Department of Anaesthesiology, Wuerzburg, Germany
Eur J Anaesthesiol 25:897-904. 2008....
Ultrasound-guided interscalene brachial plexus anaesthesia: differences in success between patients of normal and excessive weightU Schwemmer
Zentrum Operative Medizin, Klinik und Poliklinik für Anästhesiologie, Universitatsklinikum Wurzburg
Ultraschall Med 27:245-50. 2006..The nerve stimulation technique uses external landmarks for the definition of the injection site. Patient obesity is, therefore, one causative factor for a reduced success rate of the blockade...
Sonographic imaging of the sciatic nerve division in the popliteal fossaU Schwemmer
Department of Anesthesiology, University Hospital Wuerzburg, Germany
Ultraschall Med 26:496-500. 2005..We wanted to evaluate the feasibility of ultrasound-guided identification of the sciatic nerve in the popliteal fossa and the correlation of the findings by ultrasound with patients' characteristics...
Transnasal transesophageal echocardiography: a modified application mode for cardiac examination in ventilated patientsC A Greim
Department of Anesthesiology, Julius Maximilians Universitat, Wurzburg, Germany
Anesth Analg 88:306-11. 1999..Imaging quality was similar to conventional transoral monoplane TEE with larger transducers, but technical restraints cause a deficit in complete cardiac diagnosing obtained with multiplane TEE...
[Clinical pathway, quality circle and standard operating procedures as tools for quality management in the trauma suite]Thomas Wurmb
Klinik und Poliklinik für Anäisthesiologie, Universitatsklinikum Wurzburg, Zentrum Operative Medizin, Oberdërrbacher str 6, 97080 Wurzburg, Bavaria, Germany
Z Evid Fortbild Qual Gesundhwes 103:49-57. 2009..In the present study we describe the implementation of a clinical pathway and an interdisciplinary quality circle to improve management of the trauma patient...
[Cholestasis and liver dysfunction in critical care patients]M Kredel
Klinik und Poliklinik für Anästhesiologie, Julius Maximilians Universitat, Wurzburg, Germany
Anaesthesist 57:1172-82. 2008..In rare cases a temporary liver surrogate is necessary. The molecular absorbent recirculating system (MARS), a form of extracorporeal albumin dialysis, is introduced as a modality for the treatment of liver failure...
Sonographic imaging of the sciatic nerve and its division in the popliteal fossa in childrenUlrich Schwemmer
Department of Anaesthesiology, University Hospital Wurzburg, Josef Schneider Strasse 2, Wurzburg, Germany
Paediatr Anaesth 14:1005-8. 2004..High resolution ultrasound is a possible option for anesthetists to detect nerves. We tested the possibility of imaging the sciatic nerve and its division into the tibial and peroneal part using high resolution ultrasound in children...
High-frequency ventilation is/is not the optimal physiological approach to ventilate ARDS patientsRalf M Muellenbach
J Appl Physiol 104:1236. 2008
