Research Topics
Species | Harald HutterSummaryAffiliation: Abteilung Zellphysiologie Country: Germany Publications
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Detail Information
Publications
Laminin alpha subunits and their role in C. elegans developmentCheng chen Huang
Department of Pathology, Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA
Development 130:3343-58. 2003..We propose this supramolecular architecture regulates adhesions and signaling between adjacent tissues...- Fluorescent reporter methodsHarald Hutter
Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada
Methods Mol Biol 351:155-73. 2006..The use of fluorescent proteins as transgenic markers and image processing of fluorescence images are briefly discussed... - The Fat-like cadherin CDH-4 controls axon fasciculation, cell migration and hypodermis and pharynx development in Caenorhabditis elegansCaroline Schmitz
Max Planck Institute for Medical Research, Jahnstr 29, 69120 Heidelberg, Germany
Dev Biol 316:249-59. 2008..Cdh-4 is expressed widely in most affected cells and tissues during embryogenesis suggesting that CDH-4 functions to ensure that proper cell contacts are made and maintained during development... - New ways to look at axons in Caenorhabditis elegansH Hutter
Max Planck Institut fur medizinische Forschung, Jahnstr 29, 69120 Heidelberg, Germany
Microsc Res Tech 48:47-54. 2000..Furthermore, I demonstrate that neuronal processes can now be traced even in the head ganglia, an area of the nervous system that was previously almost inaccessible for analysis due to the compact arrangement of cell bodies and axons... - Conservation and novelty in the evolution of cell adhesion and extracellular matrix genesH Hutter
Max Planck Institute for Medical Research, Jahnstrasse 29, 69120 Heidelberg, Germany
Science 287:989-94. 2000..A strategy for concerted evolution of new gene families, as well as conservation of adaptive genes, may underlie the differences between heterochromatin and euchromatin... - Extracellular cues and pioneers act together to guide axons in the ventral cord of C. elegansHarald Hutter
Max Planck Institute for Medical Research, Jahnstrasse 29, 69120 Heidelberg, Germany
Development 130:5307-18. 2003..Different groups of axons growing in the same axon bundle apparently use different combinations of guidance cues for their navigation and can navigate largely independently... - Novel genes controlling ventral cord asymmetry and navigation of pioneer axons in C. elegansHarald Hutter
Max Planck Institut fur medizinische Forschung, Jahnstr 29, 69120 Heidelberg, Germany
Dev Biol 284:260-72. 2005..Taken together, these genes provide a basis to address different aspects of axon navigation within the ventral cord of C. elegans... - Five-colour in vivo imaging of neurons in Caenorhabditis elegansH Hutter
Max Planck Institute for Medical Research, Jahnstr 29, 69120 Heidelberg, Germany
J Microsc 215:213-8. 2004..The use of five distinct marker dyes allows the in vivo analysis of the Caenorhabditis elegans nervous system at unprecedented resolution and richness in detail at the light microscopic level... - AST-1, a novel ETS-box transcription factor, controls axon guidance and pharynx development in C. elegansChristina Schmid
Max Planck Institute for Medical Research, Jahnstr 29, 69120 Heidelberg, Germany
Dev Biol 293:403-13. 2006.... - zag-1, a Zn-finger homeodomain transcription factor controlling neuronal differentiation and axon outgrowth in C. elegansIrene Wacker
Max Planck Institute for Medical Research, Jahnstrasse 29, 69120 Heidelberg, Germany
Development 130:3795-805. 2003..Our data indicate that zag-1 also acts as transcriptional repressor controlling important aspects of terminal differentiation of neurons... - IgCAMs redundantly control axon navigation in Caenorhabditis elegansValentin Schwarz
Max Planck Institute for Medical Research, Heidelberg, Germany
Neural Dev 4:13. 2009..The Caenorhabditis elegans genome contains a comparatively small number of IgCAMs, most of which are evolutionarily conserved and found across all animal phyla. Only some of these have been functionally characterized so far... - Axon guidance genes identified in a large-scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin-15b(hd126)Caroline Schmitz
Max Planck Institute for Medical Research, Jahnstrasse 29, 69120 Heidelberg, Germany
Proc Natl Acad Sci U S A 104:834-9. 2007..Our screen provides insights into molecular pathways operating during the generation of neuronal circuits and provides a basis for a more detailed analysis of gene networks regulating axon navigation... - Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegansMichael Morcos
Department of Medicine I and Clinical Chemistry, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
Aging Cell 7:260-9. 2008..elegans lifespan. In contrast, knock-down of CeGly increases MG modifications of mitochondrial proteins and mitochondrial ROS production, and decreases C. elegans lifespan... - A novel nuclear receptor/coregulator complex controls C. elegans lipid metabolism, larval development, and agingAndreas H Ludewig
MPI fuer molekulare Genetik, 14195 Berlin, Germany
Genes Dev 18:2120-33. 2004..We propose that the DIN-1S/DAF-12 complex serves as a molecular switch that implements slow life history alternatives in response to diminished hormonal signals... - CASY-1, an ortholog of calsyntenins/alcadeins, is essential for learning in Caenorhabditis elegansDaisuke D Ikeda
Molecular Genetics Research Laboratory and Department of Biophysics and Biochemistry, Graduate School of Science, University of Tokyo, Bunkyo ku, Tokyo 113 0033, Japan
Proc Natl Acad Sci U S A 105:5260-5. 2008..These results suggest that learning is modulated by the released ectodomain of CASY-1... - The C. elegans L1CAM homologue LAD-2 functions as a coreceptor in MAB-20/Sema2 mediated axon guidanceXuelin Wang
Department of Genetics, Cell Biology, and Development, Developmental Biology Center, University of Minnesota, Minneapolis, MN 55455, USA
J Cell Biol 180:233-46. 2008..In vertebrates, L1 binds neuropilin1, the obligate receptor to the secreted Sema3A. However, invertebrates lack neuropilins. LAD-2 may thus function in the semaphorin complex by combining the roles of neuropilins and L1CAMs... - The RhoGAP RGA-2 and LET-502/ROCK achieve a balance of actomyosin-dependent forces in C. elegans epidermis to control morphogenesisMarie Diogon
IGBMC, CNRS INSERM ULP, 1 rue Laurent Fries, BP 10142, 67400 Illkirch, France
Development 134:2469-79. 2007..We propose that actomyosin-generated tension must be moderated in two out of the three sets of epidermal cells surrounding the C. elegans embryo to achieve morphogenesis... - DRE-1: an evolutionarily conserved F box protein that regulates C. elegans developmental ageNicole Fielenbach
Baylor College of Medicine, Huffington Center on Aging, Department of Molecular and Cellular Biology, One Baylor Plaza, Houston, TX 77030, USA
Dev Cell 12:443-55. 2007..The identification of core components involved in SCF-mediated modification and/or proteolysis suggests an important level of regulation in the heterochronic hierarchy... - UNC-39, the C. elegans homolog of the human myotonic dystrophy-associated homeodomain protein Six5, regulates cell motility and differentiationJudith L Yanowitz
Department of Embryology, Carnegie Institution of Washington, Baltimore, MD 21210, USA
Dev Biol 272:389-402. 2004..We show that human Six5 and UNC-39 are functional homologs, suggesting that further characterization of the C. elegans unc-39 gene might provide insight into the etiology of DM1... - Global cell sorting in the C. elegans embryo defines a new mechanism for pattern formationRalf Schnabel
Technische Universität Braunschweig Carolo Wilhelmina, Institut fur Genetik, Spielmann Str 7, D 38106 Braunschweig, Germany
Dev Biol 294:418-31. 2006..We call this new mechanism "cell focusing". When the fate of cells is changed, they move to new positions which also affect the shape of the body. Thus, this process is also important for morphogenesis... - A differential cytolocalization assay for analysis of macromolecular assemblies in the eukaryotic cytoplasmDaniel Blanchard
Departments of Pathology and Genetics, Stanford University School of Medicine, Stanford, California 94305 5324, USA
Mol Cell Proteomics 5:2175-84. 2006.... - Hemicentin assembly in the extracellular matrix is mediated by distinct structural modulesChun Dong
Medical Biotechnology Center, University of Maryland Biotechnology Institute, Baltimore, Maryland 21201, USA
J Biol Chem 281:23606-10. 2006.... - Synaptic tetraspan vesicle membrane proteins are conserved but not needed for synaptogenesis and neuronal function in Caenorhabditis elegansChristian Abraham
Department of Anatomy and Cell Biology, Johannes Gutenberg University, Becherweg 13, 55128 Mainz, Germany
Proc Natl Acad Sci U S A 103:8227-32. 2006..We therefore conclude that TVPs are not needed for the basic neuronal machinery and instead may contribute to subtle higher order functions... - The immunoglobulin superfamily in Caenorhabditis elegans and Drosophila melanogasterOliver Hobert
Development 131:2237-8; author reply 2238-40. 2004 - Fibulin-1C and Fibulin-1D splice variants have distinct functions and assemble in a hemicentin-dependent mannerJoaquin M Muriel
Program in Cell Structure and Development, Medical Biotechnology Center, University of Maryland Biotechnology Institute, Baltimore, MD 21201, USA
Development 132:4223-34. 2005..We suggest that the distinct developmental roles and hemicentin-dependent assembly for fibulin-1 splice variants demonstrated here may be relevant to fibulin-1 and possibly other fibulin family members in non-nematode species...