Isabel García-Arnandis

Summary

Publications

  1. ncbi High mobility group box 1 potentiates the pro-inflammatory effects of interleukin-1? in osteoarthritic synoviocytes
    Isabel García-Arnandis
    Department of Pharmacology, University of Valencia, Valencia, Spain
    Arthritis Res Ther 12:R165. 2010
  2. ncbi Control of cell migration and inflammatory mediators production by CORM-2 in osteoarthritic synoviocytes
    Isabel García-Arnandis
    Department of Pharmacology and IDM, University of Valencia, Valencia, Spain
    PLoS ONE 6:e24591. 2011
  3. ncbi Haem oxygenase-1 down-regulates high mobility group box 1 and matrix metalloproteinases in osteoarthritic synoviocytes
    Isabel García-Arnandis
    Department of Pharmacology, University of Valencia, Valencia, Spain
    Rheumatology (Oxford) 49:854-61. 2010
  4. ncbi New molecular targets for the treatment of osteoarthritis
    Maria José Alcaraz
    Department of Pharmacology, University of Valencia, Av Vicent Andres Estelles s n, 46100 Burjasot, Valencia, Spain
    Biochem Pharmacol 80:13-21. 2010

Detail Information

Publications4

  1. ncbi High mobility group box 1 potentiates the pro-inflammatory effects of interleukin-1? in osteoarthritic synoviocytes
    Isabel García-Arnandis
    Department of Pharmacology, University of Valencia, Valencia, Spain
    Arthritis Res Ther 12:R165. 2010
    ..We have recently reported that HMGB1 is released by osteoarthritic synoviocytes after activation with interleukin-1beta (IL-1?) The present study investigated the role of HMGB1 in synovial inflammation in osteoarthritis (OA)...
  2. ncbi Control of cell migration and inflammatory mediators production by CORM-2 in osteoarthritic synoviocytes
    Isabel García-Arnandis
    Department of Pharmacology and IDM, University of Valencia, Valencia, Spain
    PLoS ONE 6:e24591. 2011
    ..We have studied the ability of CORM-2 to modify the migration of human OA synoviocytes and the production of chemokines and other mediators sustaining inflammatory and catabolic processes in the OA joint...
  3. ncbi Haem oxygenase-1 down-regulates high mobility group box 1 and matrix metalloproteinases in osteoarthritic synoviocytes
    Isabel García-Arnandis
    Department of Pharmacology, University of Valencia, Valencia, Spain
    Rheumatology (Oxford) 49:854-61. 2010
    ..In this study, we have examined whether HO-1 induction would be an effective strategy to control MMP and HMGB1 production in osteoarthritic synoviocytes...
  4. ncbi New molecular targets for the treatment of osteoarthritis
    Maria José Alcaraz
    Department of Pharmacology, University of Valencia, Av Vicent Andres Estelles s n, 46100 Burjasot, Valencia, Spain
    Biochem Pharmacol 80:13-21. 2010
    ..Further insights into the molecular mechanisms involved in OA initiation and progression may lead to the development of new therapies able to control joint destruction and repair...