Treatment of Colorectal Peritoneal Carcinomatosis With Systemic Chemotherapy: A Pooled Analysis of North Central Cancer Treatment Group Phase III Trials N9741 and N9841Jan Franko
411 Laurel St, Ste 2100, Des Moines, IA 50314
J Clin Oncol 30:263-7. 2012
..66, P < .001). CONCLUSION pcCRC is associated with a significantly shorter OS and PFS as compared with other manifestations of mCRC. Future trials for mCRC should consider stratifying on the basis of pcCRC status...
- Conversion of laparoscopic colon resection does not affect survival in colon cancer
Jan Franko
Department of Surgery, Abington Memorial Hospital, Abington, PA, USA
Surg Endosc 22:2631-4. 2008
..Conversion of laparoscopic procedures, however, was associated with decreased survival in colon cancer patients in the only prior study examining this question. We conducted this study to evaluate the effect of conversion on survival...
- Multivisceral resection does not affect morbidity and survival after cytoreductive surgery and chemoperfusion for carcinomatosis from colorectal cancer
Jan Franko
Division of Surgical Oncology, University of Pittsburgh Medical Center, 5150 Centre Ave, Rm 414, Pittsburgh, PA 15232, USA
Ann Surg Oncol 15:3065-72. 2008
..This procedure commonly involves multivisceral resection (MVR) with potentially high morbidity. We analyzed the effect of MVR on the outcome after CS-HIPEC...
- Impact of radiation therapy sequence on survival among patients with resected pancreatic head ductal carcinoma
Jan Franko
Division of Surgical Oncology, Mercy Medical Center, Des Moines, IA, USA
Ann Surg Oncol 19:26-30. 2012
..The purpose of this study is to compare the impact of the sequencing of radiation therapy and surgery on overall survival (OS) of patients, who received both pancreaticoduodenectomy and radiation therapy...
- The influence of prior abdominal operations on conversion and complication rates in laparoscopic colorectal surgery
Jan Franko
Department of Surgery, Abington Memorial Hospital, Abington, Pennsylvania 19001, USA
JSLS 10:169-75. 2006
..This study compares the conversion rates of patients with and without a prior abdominal operation (PAO)...
- Choledochal cyst cholangiocarcinoma arising from adenoma: case report and a review of the literature
Jan Franko
Department of Surgery, Abington Memorial Hospital, PA 19001, USA
Curr Surg 63:281-4. 2006
..Association of choledochal cyst with pancreaticobiliary anomalies is reviewed...
- Advanced age and preinjury warfarin anticoagulation increase the risk of mortality after head trauma
Jan Franko
Department of Surgery, Abington Memorial Hospital, Abington, Pennsylvania 19001, USA
J Trauma 61:107-10. 2006
..A large population of patients on oral anticoagulants is exposed to the risk of traumatic brain injury (TBI). Effects of age and anticoagulation on TBI outcomes need to be assessed separately...
- Cytoreductive surgery and hyperthermic intraperitoneal chemoperfusion versus systemic chemotherapy alone for colorectal peritoneal carcinomatosis
Jan Franko
Division of Surgical Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15232, USA
Cancer 116:3756-62. 2010
..Because of a recent substantial improvement in chemotherapy, the authors analyzed treatment options of colorectal carcinomatosis in the current era...
- Outcomes in patients treated by laparoscopic resection of rectal carcinoma after neoadjuvant therapy for rectal cancer
Masoud Rezvani
Department of Surgery, Abington Memorial Hospital, Abington, Pennsylvania 19001, USA
JSLS 11:204-7. 2007
..We analyzed the effect of neoadjuvant chemo radiation on feasibility and outcomes in rectal cancer patients undergoing laparoscopic resection of the rectum...
- Non-functional neuroendocrine carcinoma of the pancreas: incidence, tumor biology, and outcomes in 2,158 patients
Jan Franko
Division of Surgical Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
J Gastrointest Surg 14:541-8. 2010
..This population-based analysis evaluated the hypothesis that long-term survival benefit is greater with aggressive, rather than limited, surgical therapy...
- Loss of heterozygosity predicts poor survival after resection of pancreatic adenocarcinoma
Jan Franko
UPMC Pancreatic Cancer Center, Division of Surgical Oncology, 497 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA
J Gastrointest Surg 12:1664-72; discussion 1672-3. 2008
..We hypothesized that genetic analysis of resected cancers would correlate with tumor biology and postoperative survival...
- Aggressive surgical management of peritoneal carcinomatosis with low mortality in a high-volume tertiary cancer center
Niraj J Gusani
Division of Surgical Oncology, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Ann Surg Oncol 15:754-63. 2008
..We report our experience performing CS-HIPEC in a high-volume regional perfusion program designed to limit morbidity and mortality...
- Characteristics and treatment of metaplastic breast cancer: analysis of 892 cases from the National Cancer Data Base
Christopher M Pezzi
Department of Surgery, Abington Memorial Hospital, 1200 Old York Road, Abington, Pennsylvania 19001, USA
Ann Surg Oncol 14:166-73. 2007
..With few published reports, we hypothesized that MBC may have markedly different characteristics at presentation than typical infiltrating ductal carcinoma (IDC) and may be managed differently...
- Multimodality therapy for pancreatic cancer
Jan Franko
Division of Surgical Oncology, University of Pittsburgh Medical Center, 497 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA
Gastroenterol Clin North Am 36:391-411, x. 2007
..The future of pancreatic cancer research rests on the availability and rapid transfer of new therapies from the laboratory to clinical research...
- Safely increasing the efficiency of thyroidectomy using a new bipolar electrosealing device (LigaSure) versus conventional clamp-and-tie technique
Jan Franko
Department of Surgery, Abington Memorial Hospital, Abington, Pennsylvania 19001, USA
Am Surg 72:132-6. 2006
..Rates of operative complications were unchanged. LigaSure use in thyroid surgery can safely increase efficiency...
