Research Topics
| H VerdouxSummaryCountry: France Publications
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Publications
Transition in care in persons with antidepressant prescription in naturalistic conditionsHelene Verdoux
Universite de Bordeaux, France
Fam Pract 28:400-5. 2011..Few studies have explored transition to psychiatric care in persons treated by antidepressants in primary care...
Is benzodiazepine use a risk factor for cognitive decline and dementia? A literature review of epidemiological studiesHelene Verdoux
EA 3676, Universite Victor Segalen Bordeaux 2, Bordeaux, France
Psychol Med 35:307-15. 2005..The aim of the present review was to examine findings from prospective studies carried out in general population samples exploring whether exposure to benzodiazepines is associated with an increased risk of incident cognitive decline...
The current state of adult mental health care in FranceHelene Verdoux
Hôpital Charles Perrens, 121 rue de la Bechade, 33076, Bordeaux Cedex, France
Eur Arch Psychiatry Clin Neurosci 257:64-70. 2007..The numerous national programmes aimed at renovating French mental health services, published over the last decade, have not yet kept their promises...
A survey of general practitioners' knowledge of symptoms and epidemiology of schizophreniaHelene Verdoux
Universite Victor Segalen Bordeaux 2, Hôpital Charles Perrens, 121 rue de la Bechade, 33076 Bordeaux Cedex, France
Eur Psychiatry 21:238-44. 2006..To explore general practitioners' (GPs) knowledge of the symptoms and epidemiology of schizophrenia, and the GPs' characteristics associated with level of knowledge...
[Cannabis use and risk of psychosis, an etiological link?]Helene Verdoux
Service universitaire de psychiatrie adulte and EA 3676 MP2S, IFR99 de Santé publique, Universite Victor Segalen, Bordeaux
Presse Med 33:551-4. 2004..If further studies confirm that cannabis is a risk factor for psychosis, its impact on the population's mental health may not be negligible considering the growing number of adolescents exposed to this substance...
Perinatal risk factors for schizophrenia: how specific are they?Helene Verdoux
Department of Psychiatry, University Bordeaux, Hôpital Charles Perrens, EA3676, 121 rue de la Bechade, 33076 Bordeaux Cedex, France
Curr Psychiatry Rep 6:162-7. 2004....
Schizophrenia: who is at risk? Who is a case?Helene Verdoux
Universite Victor Segalen Bordeaux 2, 33076 Bordeaux, France
Int Clin Psychopharmacol 21:S17-9. 2006..This strategy has major clinical implications because the question "who is a case?" is often equivalent in clinical practice to the question "who needs treatment?"...
[Pharmacoepidemiology of psychotropic medication: utilisation and impact in real-life conditions]Helene Verdoux
Universite Victor Segalen Bordeaux 2, Bordeaux, France
Therapie 61:17-22. 2006..Only findings obtained by such studies may allow risk management and elaboration of guidelines based upon factual data...
Impact of substance use on the onset and course of early psychosisHelene Verdoux
EA 3676, IFR of Public Health, University Victor Segalen Bordeaux 2, Bordeaux, France
Schizophr Res 79:69-75. 2005..Therapeutic programs for subjects with dual diagnosis should be implemented early in the course of psychosis to maximise their impact on the course of illness...
Impact of duration of antidepressant treatment on the risk of occurrence of a new sequence of antidepressant treatmentH Verdoux
Universite Bordeaux 2, Bordeaux, France
Pharmacopsychiatry 44:96-101. 2011..The study was aimed at exploring the impact of early discontinuation of antidepressant treatment on the risk of antidepressant re-initiation...
[Occupational outcome of patients with schizophrenia after first request for disability status: a 2-year follow-up study]H Verdoux
Inserm U657 pharmacoépidémiologie et évaluation de l impact des produits de santé sur les populations, IFR99 santé publique, Centre Hospitalier Charles Perrens, Universite Victor Segalen Bordeaux 2, 33076 Bordeaux, France
Encephale 36:484-90. 2010..To assess occupational outcome of persons with schizophrenia over the 2 years following the first request of disability status...
Self-perceived cognitive deficits and occupational outcome in persons with schizophreniaHelene Verdoux
Inserm U657 pharmacoépidémiologie et évaluation de l impact des produits de santé sur les populations, Université Bordeaux2, 146 rue Leo Saignat 33076 Bordeaux Cedex, France
Psychiatry Res 178:437-9. 2010..Measures of cognitive complaints should be complemented by objective testing to assess potential for vocational rehabilitation...
How do general practitioners manage subjects with early schizophrenia and collaborate with mental health professionals? A postal survey in South-Western FranceHelene Verdoux
Department of Adult Psychiatry, Universite Victor Segalen Bordeaux 2, Bordeaux, France
Soc Psychiatry Psychiatr Epidemiol 40:892-8. 2005..This study was conducted to explore how general practitioners (GPs) manage subjects with early psychosis and collaborate with psychiatrists in the care of such patients...
Antipsychotic use patterns in persons initially treated with mood stabilizers: a naturalistic studyH Verdoux
INSERM U657, Universite Victor Segalen, Bordeaux 2, France
Pharmacopsychiatry 43:17-23. 2010..Little information is available on the pattern of use of antipsychotics in naturalistic conditions in persons initially treated with "conventional" mood stabilizers (lithium and anticonvulsants)...
From conduct disorder to severe mental illness: a risky pathwayH Verdoux
, INSERM U657, Bordeaux, France
Psychol Med 38:927-8. 2008
The prognostic impact of psychotropic drugs in intentional drug overdoseM Tournier
Unité INSERM U657, Universite Victor Segalen, Hôpital Charles Perrens, Bordeaux, France
Pharmacopsychiatry 42:51-6. 2009..Psychotropic drugs belong to the drugs most frequently involved in intentional drug overdose (IDO). Few studies have explored their prognostic impact during hospitalisation for IDO...
Impact of antidepressants on the risk of suicide in patients with depression in real-life conditions: a decision analysis modelA Cougnard
University Victor Segalen Bordeaux 2, INSERM U657, IFR of Public Health, Bordeaux, France
Psychol Med 39:1307-15. 2009..The aim of this study was to determine in a real-life setting whether ADT is associated with an increased or a reduced risk of suicide compared to absence of ADT (no-ADT) in patients with depression...
[Prescription practices of antipsychotic medication in early psychosis: a two-year follow-up survey of subjects admitted in two psychiatric hospitals of South-Western France]A Grolleau
Universite Victor Segalen Bordeaux 2, Bordeaux, France
Encephale 33:326-31. 2007....
Pattern of health service utilization and predictors of readmission after a first admission for psychosis: a 2-year follow-up studyA Cougnard
University Victor Segalen Bordeaux2, Bordeaux, France
Acta Psychiatr Scand 113:340-9. 2006..Development of psychotherapeutic programs for subjects with early psychosis who have enduring psychotic symptoms at first discharge should be promoted...
Prognostic impact of psychoactive substances use during hospitalization for intentional drug overdoseM Tournier
EA 3676, IFR99 of Public Health, 33076
Acta Psychiatr Scand 112:134-40. 2005..CONCLUSION: Systematic investigation of substance use could be important to adapt medical management of subjects with IDO in general hospital, but also in primary care and psychiatric settings...
Congruence between diagnosis of recurrent major depressive disorder and psychotropic treatment in the general populationA Grolleau
University Victor Segalen Bordeaux 2, Bordeaux, France
Acta Psychiatr Scand 117:20-7. 2008..We explored in a sample representative of the French general population the congruence between lifetime use of psychotropic drugs and diagnosis of recurrent major depressive disorder (rMDD)...
[Psychotropic drug use and correspondence with psychiatric diagnoses in the mental health in the general population survey]A Grolleau
Universite Victor Segalen Bordeaux 2, 146, rue Leo Saignat, 33076 Bordeaux Cedex, France
Encephale 34:352-9. 2008..The aims of this study were to assess the lifetime prevalence rate of psychotropic drugs use in the French general population and the correspondence between psychotropic drug use and psychiatric diagnoses...
A one-day survey of characteristics of off-label hospital prescription of psychotropic drugsK Martin Latry
Universite Victor Segalen Bordeaux 2, Bordeaux, France
Pharmacopsychiatry 40:116-20. 2007..The aim of this study was to explore the characteristics of off-label prescriptions of psychotropic drugs among patients hospitalised in psychiatry...
Is the association between duration of untreated psychosis and outcome confounded? A two year follow-up study of first-admitted patientsH Verdoux
Department of Psychiatry, University Victor Segalen, Bordeaux 2, 121 rue Bechiade, 33076, Cedex, Bordeaux, France
Schizophr Res 49:231-41. 2001..To assess whether a long duration of untreated psychosis (DUP) before first admission predicts poor clinical and social outcome, and whether this association, if any, is confounded by premorbid and clinical characteristics...
Antidepressants: psychiatrists' opinions and clinical practiceF Depont
Departments of Pharmacology and Adult Psychiatry, Public Health Research Institute IFR99, , Bordeaux, France
Acta Psychiatr Scand 108:24-31. 2003..CONCLUSION: The best predictors for the prescribed antidepressants were the psychiatrists' overall rankings and opinions of the tolerability of the drug...
Patterns of risperidone prescription: a utilization study in south-west FranceK Martin
Departement de Pharmacologie, IFR de Santé Publique, Universite Victor Segalen, Bordeaux, France
Acta Psychiatr Scand 109:202-6. 2004..To describe the patterns of prescriptions associated with risperidone in naturalistic clinical practice...
Pathways to care of first-admitted subjects with psychosis in South-Western FranceA Cougnard
IFR 99 of Public Health, , Bordeaux, France
Psychol Med 34:267-76. 2004....
A prospective longitudinal study of the impact of early postnatal vs. chronic maternal depressive symptoms on child developmentA L Sutter-Dallay
University Victor Segalen Bordeaux 2, Bordeaux, France EA 4139, IFR of Public Health, Bordeaux, France
Eur Psychiatry 26:484-9. 2011..We investigated whether early postnatal depressive symptoms (PNDS) predicted child developmental outcome independently of later maternal depressive symptoms...
Antipsychotic prescribing trends: a review of pharmaco-epidemiological studiesH Verdoux
INSERM U657, Université Victor Segalen Bordeaux2, Bordeaux Cedex, France
Acta Psychiatr Scand 121:4-10. 2010..To review findings from pharmaco-epidemiological studies exploring antipsychotic (AP) drugs prescribing trends...
Predictors and outcome characteristics associated with suicidal behaviour in early psychosis: a two-year follow-up of first-admitted subjectsH Verdoux
Department of Psychiatry, University Victor Segalen Bordeaux 2, France, , Bordeaux, France, University of Maastricht, The Netherlands
Acta Psychiatr Scand 103:347-54. 2001..CONCLUSION: Subjects with a previous history of parasuicide, with a deteriorating clinical course, or with substance misuse are at increased risk of suicidal behaviour in the 2 years after the onset of a first psychotic episode...
Seasonality of birth in schizophrenia: the effect of regional population densityH Verdoux
Department of Psychiatry, University Victor Segalen Bordeaux 2, Centre Carreire, France
Schizophr Res 23:175-80. 1997..These results suggest that seasonal early environmental risk factor(s) linked to schizophrenia predominantly operate in urban areas...
Substance use and the course of early psychosis: a 2-year follow-up of first-admitted subjectsF Sorbara
Department of Psychiatry, University Victor Segalen, Bordeaux 2, France
Eur Psychiatry 18:133-6. 2003..Early identification and treatment of substance use is essential in the care of subjects with incipient psychosis...
[Duration of antidepressant drug treatment and its determinants in France]M Tournier
Unité INSERM U657, Universite Victor Segalen Bordeaux 2, 146, rue Leo Saignat, 33076 Bordeaux Cedex, France
Encephale 37:S36-41. 2011..Practice guidelines recommend maintaining antidepressant treatment for a long duration (at least six months) after symptomatic improvement. In practice, treatment effectiveness is often jeopardized by non-persistence...
[Effect of comorbid substance use on neuropsychological performance in subjects with psychotic or mood disorders]F Liraud
, , , 121, , 33076 Bordeaux, France
Encephale 28:160-8. 2002..Since there is a high prevalence of a comorbid substance use disorder in subjects with psychotic or mood disorder, the exclusion of these patients in neuropsychological studies may not be systematically justified...
Temperament in bipolar illness: impact on prognosisC Henry
Service Universitaire de Psychiatrie, CHS Charles Perrens, Bordeaux, France
J Affect Disord 56:103-8. 1999..The present study was designed to investigate the relations between temperament and outcome in bipolar illness...
Association between temperamental characteristics and medication adherence in subjects presenting with psychotic or mood disordersF Liraud
Department of Psychiatry, University Victor Segalen Bordeaux 2, , , 33076 Cedex, Bordeaux, France
Psychiatry Res 102:91-5. 2001..Higher general SSS scores, and disinhibition and boredom susceptibility SSS subscores were associated with a greater risk to present with poor medication adherence...
[Long-term psychiatric and behavioural consequences of prenatal exposure to psychoactive drugs]H Verdoux
Service Universitaire de Psychiatrie, Universite Victor Segalen Bordeaux 2, Bordeaux, France
Therapie 57:181-5. 2002..Further studies are required to explore the long-term cognitive and behavioural consequences of prenatal exposure to psychoactive drugs and xenoestrogens...
Accuracy of self-report and toxicological assays to detect substance misuse disorders in parasuicide patientsM Tournier
Department of Psychiatry, Universite Victor Segalen Bordeaux 2, Hôpital Charles Perrens, 121 rue de la Bechade, 33076 Bordeaux Cedex, France
Acta Psychiatr Scand 108:410-8. 2003..To assess the accuracy of self-reported substance use and toxicological assays in subjects admitted for Intentional Drug Overdose (IDO), using as a reference diagnosis of substance use disorder...
[A case of Parkinsonian syndrome, cognitive impairment and hyperammonemia induced by divalproate sodium prescribed for bipolar disorder]C Ricard
, , , , Bordeaux, France
Encephale 31:98-101. 2005..A drug adverse reaction should always be considered when a patient treated with valproate presents with extrapyramidal symptoms and cognitive disorders even when valproate concentrations are within standard therapeutic ranges...
Women with anxiety disorders during pregnancy are at increased risk of intense postnatal depressive symptoms: a prospective survey of the MATQUID cohortA L Sutter-Dallay
EA 3676, IFR 99 of Public Health, Department of Psychiatry, University Victor Segalen Bordeaux 2, Bordeaux, France
Eur Psychiatry 19:459-63. 2004..7, 95%CI 1.1-6.3, P = 0.03). CONCLUSION: Promoting the recognition and management of AD in pregnant women may be of interest for the prevention of postnatal depression...
Cannabis use and risk of psychosis: an etiological link?Helene Verdoux
Department of Psychiatry, EA 3676 MP2S, IFR99 of Public Health, University Victor Segalen Bordeaux2, Bordeaux, France
Epidemiol Psichiatr Soc 13:113-9. 2004..The nature of the link between cannabis use and psychosis remains to be clarified...
Obstetrical complications and the development of postpartum depressive symptoms: a prospective survey of the MATQUID cohortH Verdoux
Departement of Psychiatry, University Victor Segalen Bordeaux 2, France
Acta Psychiatr Scand 106:212-9. 2002..To prospectively investigate in a cohort of pregnant women the association between obstetrical complications (OCs) and depressive symptomatology in the early postpartum period...
[Chronic renal complications induced by lithium]V Le Roy
Universite Victor Segalen Bordeaux 2, Bordeaux, France
Encephale 35:605-10. 2009..After 40 years of use of lithium in the treatment of mood disorders, the renal risks associated with the long-term exposure to lithium are better known...
Effects of cannabis and psychosis vulnerability in daily life: an experience sampling test studyH Verdoux
Department of Psychiatry, INSERM U330 and the Laboratory of Clinical Psychology and Psychopathology, University Victor Segalen, Bordeaux, France
Psychol Med 33:23-32. 2003..CONCLUSION: Cannabis use interacts with psychosis vulnerability in their effects on experience of psychosis in daily life. The public health impact of the widespread use of cannabis may be considerable...
Is early adulthood a critical developmental stage for psychosis proneness? A survey of delusional ideation in normal subjectsH Verdoux
Department of Psychiatry, University Victor Segalen Bordeaux, France
Schizophr Res 29:247-54. 1998....
[Postpartum mania induced by Bromocriptine: a case report]D Misdrahi
Service Universitaire de Psychiatrie, EA 3676, ,
J Gynecol Obstet Biol Reprod (Paris) 35:79-81. 2006..This case report highlights the need to systematically explore the personal history of pregnant women in search of mood disorder which may proscribe use of bromocriptine...
Psychiatric disorders and their comorbidity in subjects with parasuicide by intentional drug overdose: prevalence and gender differencesMarie Tournier
Université Victor Segalen Bordeaux2, INSERM U657, IFR99 of Public Health, 146 rue Leo Saignat, 33076 Bordeaux, France
Psychiatry Res 136:93-100. 2005....
The 4-Point ordinal Alliance Self-report: a self-report questionnaire for assessing therapeutic relationships in routine mental healthDavid Misdrahi
Departement de psychiatrie adulte, Centre Hospitalier Charles Perrens, Bordeaux, France
Compr Psychiatry 50:181-5. 2009..A secondary objective was to assess the scale's validity and the association between TR and adherence...
Efficiency and safety of oxcarbazepine in mood disorders: a naturalistic study exploring the interest of plasma dosagesDavid Misdrahi
Pôle 347 de Psychiatrie Adulte, Centre Hospitalier Charles Perrens, 121 rue de la Bechade, 33076 Bordeaux Cedex, France
Eur Psychiatry 23:409-12. 2008..To investigate whether measurement of plasma levels can predict tolerance to oxcarbazepine (OXC)...
