D A Tregouet

Summary

Country: France

Publications

  1. ncbi Applications of the estimating equations theory to genetic epidemiology: a review
    D A Tregouet
    INSERM Unite 525, Paris, France
    Ann Hum Genet 64:1-14. 2000
  2. ncbi Sample size calculations for classical association and TDT-type methods using family data
    D A Tregouet
    INSERM Unite 525, Paris, France
    Ann Hum Genet 65:293-312. 2001
  3. ncbi Combined segregation-linkage analysis of plasma thrombin activatable fibrinolysis inhibitor (TAFI) antigen levels with TAFI gene polymorphisms
    D A Tregouet
    INSERM U525, Epidemiological and Molecular Genetics of Cardiovascular Diseases, 91 Bd de l Hopital, 75634 Paris Cedex 13, France, Paris
    Hum Genet 109:191-7. 2001
  4. ncbi Specific haplotypes of the P-selectin gene are associated with myocardial infarction
    David Alexandre Tregouet
    INSERM U525, Faculte de Medecine, Hopital Pitie Salpetriere, 91 Bld de l Hôpital, 75634 Paris, France
    Hum Mol Genet 11:2015-23. 2002
  5. ncbi Exploration of multilocus effects in a highly polymorphic gene, the apolipoprotein (APOB) gene, in relation to plasma apoB levels
    N Tahri-Daizadeh
    INSERM U525, Faculte de Medecine, Hopital Pitie Salpetriere, 91 Bld de l Hôpital, 75634 Paris, France
    Ann Hum Genet 68:405-18. 2004
  6. ncbi A new algorithm for haplotype-based association analysis: the Stochastic-EM algorithm
    D A Tregouet
    INSERM U525 2INSERM U436, Paris, France
    Ann Hum Genet 68:165-77. 2004
  7. ncbi SELPLG gene polymorphisms in relation to plasma SELPLG levels and coronary artery disease
    D A Tregouet
    INSERM U525, Faculte de Medecine, Hopital Pitie Salpetriere, 91 Bld de l Hôpital, 75634 Paris Cedex 13, France
    Ann Hum Genet 67:504-11. 2003
  8. ncbi Cox proportional hazards survival regression in haplotype-based association analysis using the Stochastic-EM algorithm
    D A Tregouet
    INSERM U525, 75634 Paris, France
    Eur J Hum Genet 12:971-4. 2004
  9. ncbi Activated thrombin activatable fibrinolysis inhibitor levels are associated with the risk of cardiovascular death in patients with coronary artery disease: the AtheroGene study
    D A Tregouet
    INSERM, UMR_S 525, F 75013, Paris, France
    J Thromb Haemost 7:49-57. 2009
  10. ncbi A new JAVA interface implementation of THESIAS: testing haplotype effects in association studies
    D A Tregouet
    INSERM, UMR S 525 and Université Pierre et Marie Curie Paris6, UMR S 525, Paris, France
    Bioinformatics 23:1038-9. 2007

Collaborators

Detail Information

Publications15

  1. ncbi Applications of the estimating equations theory to genetic epidemiology: a review
    D A Tregouet
    INSERM Unite 525, Paris, France
    Ann Hum Genet 64:1-14. 2000
    ....
  2. ncbi Sample size calculations for classical association and TDT-type methods using family data
    D A Tregouet
    INSERM Unite 525, Paris, France
    Ann Hum Genet 65:293-312. 2001
    ..In a phenotype-first strategy, this number may be critical when investigating costly phenotypes...
  3. ncbi Combined segregation-linkage analysis of plasma thrombin activatable fibrinolysis inhibitor (TAFI) antigen levels with TAFI gene polymorphisms
    D A Tregouet
    INSERM U525, Epidemiological and Molecular Genetics of Cardiovascular Diseases, 91 Bd de l Hopital, 75634 Paris Cedex 13, France, Paris
    Hum Genet 109:191-7. 2001
    ..The putative QTLs also did not seem compatible with the other TAFI gene polymorphisms that we have previously described. More extensive sequencing of the TAFI gene is necessary to identify the functional variants...
  4. ncbi Specific haplotypes of the P-selectin gene are associated with myocardial infarction
    David Alexandre Tregouet
    INSERM U525, Faculte de Medecine, Hopital Pitie Salpetriere, 91 Bld de l Hôpital, 75634 Paris, France
    Hum Mol Genet 11:2015-23. 2002
    ..This finding illustrates the complexity of the relationship between gene variability and disease and the necessity to explore in detail the polymorphisms of candidate genes...
  5. ncbi Exploration of multilocus effects in a highly polymorphic gene, the apolipoprotein (APOB) gene, in relation to plasma apoB levels
    N Tahri-Daizadeh
    INSERM U525, Faculte de Medecine, Hopital Pitie Salpetriere, 91 Bld de l Hôpital, 75634 Paris, France
    Ann Hum Genet 68:405-18. 2004
    ..Additionally, DICE identified the E4154K (EcoRI) and the T2488T (XbaI) polymorphisms as potentially interesting. This selection was not modified by inclusion of the common APOE polymorphism in the analysis...
  6. ncbi A new algorithm for haplotype-based association analysis: the Stochastic-EM algorithm
    D A Tregouet
    INSERM U525 2INSERM U436, Paris, France
    Ann Hum Genet 68:165-77. 2004
    ....
  7. ncbi SELPLG gene polymorphisms in relation to plasma SELPLG levels and coronary artery disease
    D A Tregouet
    INSERM U525, Faculte de Medecine, Hopital Pitie Salpetriere, 91 Bld de l Hôpital, 75634 Paris Cedex 13, France
    Ann Hum Genet 67:504-11. 2003
    ..Haplotype analysis revealed that two polymorphisms of SELPLG, the M62I and the VNTR, independently influenced plasma SELPLG levels. Conversely, haplotypes of SELPLG were not associated with CAD risk...
  8. ncbi Cox proportional hazards survival regression in haplotype-based association analysis using the Stochastic-EM algorithm
    D A Tregouet
    INSERM U525, 75634 Paris, France
    Eur J Hum Genet 12:971-4. 2004
    ..This model has been implemented in the THESIAS software freely available at http://www.genecanvas.org...
  9. ncbi Activated thrombin activatable fibrinolysis inhibitor levels are associated with the risk of cardiovascular death in patients with coronary artery disease: the AtheroGene study
    D A Tregouet
    INSERM, UMR_S 525, F 75013, Paris, France
    J Thromb Haemost 7:49-57. 2009
    ..Thrombin activatable fibrinolysis inhibitor (TAFI) attenuates fibrinolysis. Results on the association between TAFI levels and the risk of coronary artery disease (CAD) are inconsistent...
  10. ncbi A new JAVA interface implementation of THESIAS: testing haplotype effects in association studies
    D A Tregouet
    INSERM, UMR S 525 and Université Pierre et Marie Curie Paris6, UMR S 525, Paris, France
    Bioinformatics 23:1038-9. 2007
    ..AVAILABILITY: The software package including documentation and example data files is freely available at http://genecanvas.ecgene.net. The source codes are also available upon request...
  11. ncbi A multi-stage multi-design strategy provides strong evidence that the BAI3 locus is associated with early-onset venous thromboembolism
    G Antoni
    INSERM UMRS 937, Universite Pierre et Marie Curie, Paris, France
    J Thromb Haemost 8:2671-9. 2010
    ..Factor VIII (FVIII) and von Willebrand factor (VWF) are two known quantitative risk factors for venous thromboembolism (VTE)...
  12. ncbi TAFI gene haplotypes, TAFI plasma levels and future risk of coronary heart disease: the PRIME Study
    P E Morange
    INSERM U626, Hematology Laboratory, Faculty of Medicine, CHU Timone, Marseille, France
    J Thromb Haemost 3:1503-10. 2005
    ....
  13. ncbi Association of plasminogen activator inhibitor (PAI)-1 (SERPINE1) SNPs with myocardial infarction, plasma PAI-1, and metabolic parameters: the HIFMECH study
    P E Morange
    INSERM, U626, Universite de la Mediterranee, Marseille, France
    Arterioscler Thromb Vasc Biol 27:2250-7. 2007
    ....
  14. ncbi P-selectin polymorphisms' influences on P-selectin serum concentrations and on their familial correlation: the STANISLAS family study
    J B Marteau
    INSERM, Equipe Génétique Cardiovasculaire du CIC 9501, Nancy, France
    J Thromb Haemost 6:920-7. 2008
    ..However, genetic characterization of soluble P-selectin remains unclear...
  15. ncbi Biological and genetic factors influencing plasma factor VIII levels in a healthy family population: results from the Stanislas cohort
    P E Morange
    Hematology Laboratory, Faculty of Medicine, INSERM U626, CHU Timone, Marseille, France
    Br J Haematol 128:91-9. 2005
    ..The D2080N polymorphism of the LRP gene weakly contributed to the variability of FVIII:C levels in this healthy population...