Jean Pierre Tassan

Summary

Country: France

Publications

  1. ncbi An overview of the KIN1/PAR-1/MARK kinase family
    Jean Pierre Tassan
    UMR6061 CNRS Génétique et Développement IFR 97 Génomique Fonctionnelle et Santé Université de Rennes 1, Faculte de Medecine, 2 avenue du Professeur Léon Bernard CS34317 35043 Rennes Cedex France
    Biol Cell 96:193-9. 2004
  2. ncbi Cell cycle regulation of pEg3, a new Xenopus protein kinase of the KIN1/PAR-1/MARK family
    Joelle Blot
    UMR 6061, Centre National de la Recherche Scientifique, IFR 97, Universite de Rennes 1, 2 Avenue du Professeur Leon Bernard, CS34317, F 35043 Rennes Cedex, France
    Dev Biol 241:327-38. 2002
  3. ncbi Cell-cycle-dependent cortical localization of pEg3 protein kinase in Xenopus and human cells
    Isabelle Chartrain
    CNRS UMR 6061 Génétique et Développement, Universite de Rennes 1, IFR140 GFAS, Faculte de Medecine, 2 Avenue du Professeur Leon Bernard, CS 34317, 35043 Rennes Cedex, France
    Biol Cell 98:253-63. 2006
  4. ncbi M-phase MELK activity is regulated by MPF and MAPK
    Caroline Badouel
    CNRS UMR 6061 Génétique et Développement, Universite de Rennes, Rennes, France
    Cell Cycle 5:883-9. 2006
  5. ncbi Human pEg3 kinase associates with and phosphorylates CDC25B phosphatase: a potential role for pEg3 in cell cycle regulation
    Noélie Davezac
    LBCMCP CNRS UMR5088, IFR109, Universite Paul Sabatier, 118 route de Narbonne, 31062 Toulouse Cedex, France
    Oncogene 21:7630-41. 2002
  6. ncbi CDC25B phosphorylated by pEg3 localizes to the centrosome and the spindle poles at mitosis
    Gladys Mirey
    LBCMCP CNRS UMR5088 IFR109 Institut d Exploration Fonctionnelle des Génomes, Universite Paul Sabatier, Toulouse, France
    Cell Cycle 4:806-11. 2005
  7. ncbi A mitochondrial-targeting signal is present in the non-catalytic domain of the MELK protein kinase
    Isabelle Chartrain
    CNRS UMR 6061 Génétique et Développement, Universite de Rennes 1, IFR140 GFAS, Faculte de Medecine, 2 Avenue du Professeur Leon Bernard, CS 34317, 35043 Rennes Cedex, France
    Cell Biol Int 31:196-201. 2007

Collaborators

  • Xavier Le Goff
  • E A Nigg
  • Isabelle Chartrain
  • Joelle Blot
  • Caroline Badouel
  • Anne Couturier
  • Gladys Mirey
  • Bernard Ducommun
  • Noélie Davezac
  • Nicolas Guyot
  • Hubert Lerivray
  • Marie Frank-Vaillant
  • Roman Körner
  • Jean Pierre Bouché
  • Muriel Quaranta
  • Carine Froment
  • Bernard Monsarrat
  • Michel Philippe
  • Véronique Baldin
  • Christian Roghi

Detail Information

Publications7

  1. ncbi An overview of the KIN1/PAR-1/MARK kinase family
    Jean Pierre Tassan
    UMR6061 CNRS Génétique et Développement IFR 97 Génomique Fonctionnelle et Santé Université de Rennes 1, Faculte de Medecine, 2 avenue du Professeur Léon Bernard CS34317 35043 Rennes Cedex France
    Biol Cell 96:193-9. 2004
    ..Some common modes of action can be deciphered for this protein kinase family...
  2. ncbi Cell cycle regulation of pEg3, a new Xenopus protein kinase of the KIN1/PAR-1/MARK family
    Joelle Blot
    UMR 6061, Centre National de la Recherche Scientifique, IFR 97, Universite de Rennes 1, 2 Avenue du Professeur Leon Bernard, CS34317, F 35043 Rennes Cedex, France
    Dev Biol 241:327-38. 2002
    ..Using Xenopus egg extracts we demonstrated that phosphorylation occurs at least in the noncatalytic domain of the kinase, suggesting that this domain might be important for pEg3 function...
  3. ncbi Cell-cycle-dependent cortical localization of pEg3 protein kinase in Xenopus and human cells
    Isabelle Chartrain
    CNRS UMR 6061 Génétique et Développement, Universite de Rennes 1, IFR140 GFAS, Faculte de Medecine, 2 Avenue du Professeur Leon Bernard, CS 34317, 35043 Rennes Cedex, France
    Biol Cell 98:253-63. 2006
    ..pEg3 was shown to interact with and phosphorylate phosphatase CDC25B, and to potentially control cell-cycle progression. Subcellular localization of pEg3 was investigated in Xenopus and human cultured cells...
  4. ncbi M-phase MELK activity is regulated by MPF and MAPK
    Caroline Badouel
    CNRS UMR 6061 Génétique et Développement, Universite de Rennes, Rennes, France
    Cell Cycle 5:883-9. 2006
    ..In addition, phosphorylation by MPF and MAPK enhances MELK activity in vitro. Taken together our results indicate that MELK phosphorylation by MPF and MAPK enhance its activity during M-phase...
  5. ncbi Human pEg3 kinase associates with and phosphorylates CDC25B phosphatase: a potential role for pEg3 in cell cycle regulation
    Noélie Davezac
    LBCMCP CNRS UMR5088, IFR109, Universite Paul Sabatier, 118 route de Narbonne, 31062 Toulouse Cedex, France
    Oncogene 21:7630-41. 2002
    ..This effect is counteracted by overexpression of CDC25B. Taken together these results suggest that pEg3 is a potential regulator of the G2/M progression and may act antagonistically to the CDC25B phosphatase...
  6. ncbi CDC25B phosphorylated by pEg3 localizes to the centrosome and the spindle poles at mitosis
    Gladys Mirey
    LBCMCP CNRS UMR5088 IFR109 Institut d Exploration Fonctionnelle des Génomes, Universite Paul Sabatier, Toulouse, France
    Cell Cycle 4:806-11. 2005
    ..Taken together, these results support a model in which pEg3 contributes to the control of progression through mitosis by phosphorylation of the CDC25 phosphatases...
  7. ncbi A mitochondrial-targeting signal is present in the non-catalytic domain of the MELK protein kinase
    Isabelle Chartrain
    CNRS UMR 6061 Génétique et Développement, Universite de Rennes 1, IFR140 GFAS, Faculte de Medecine, 2 Avenue du Professeur Leon Bernard, CS 34317, 35043 Rennes Cedex, France
    Cell Biol Int 31:196-201. 2007
    ..These results demonstrate the presence of a mitochondrial targeting signal at the N-terminus of the MC domain of MELK. This mitochondrial targeting signal was also functional in human HeLa cells...