Olivier Sperandio

Summary

Country: France

Publications

  1. ncbi Ligand scaffold hopping combining 3D maximal substructure search and molecular similarity
    Flavien Quintus
    MTI, RPBS, INSERM UMR S973, Universite Paris Diderot Paris 7, Paris, France
    BMC Bioinformatics 10:245. 2009
  2. ncbi FAF-Drugs2: free ADME/tox filtering tool to assist drug discovery and chemical biology projects
    David Lagorce
    INSERM U648, MTi team, Paris Descartes University, Paris Diderot University, Paris, France
    BMC Bioinformatics 9:396. 2008
  3. ncbi Rationalizing the chemical space of protein-protein interaction inhibitors
    Olivier Sperandio
    CDithem Platform IGM, 27 rue Juliette Dodu, 75010 Paris, France
    Drug Discov Today 15:220-9. 2010

Detail Information

Publications3

  1. ncbi Ligand scaffold hopping combining 3D maximal substructure search and molecular similarity
    Flavien Quintus
    MTI, RPBS, INSERM UMR S973, Universite Paris Diderot Paris 7, Paris, France
    BMC Bioinformatics 10:245. 2009
    ..To date, very few methods performing this task are easily available to the scientific community...
  2. ncbi FAF-Drugs2: free ADME/tox filtering tool to assist drug discovery and chemical biology projects
    David Lagorce
    INSERM U648, MTi team, Paris Descartes University, Paris Diderot University, Paris, France
    BMC Bioinformatics 9:396. 2008
    ..Clearly, these rules cannot assess the full complexity of the human body but can provide valuable information and assist decision-making...
  3. ncbi Rationalizing the chemical space of protein-protein interaction inhibitors
    Olivier Sperandio
    CDithem Platform IGM, 27 rue Juliette Dodu, 75010 Paris, France
    Drug Discov Today 15:220-9. 2010
    ..Key characteristics of i-PPIs can then be revealed and highlight the importance of specific shapes and/or aromatic bonds, enabling the design of i-PPI-enriched focused libraries and, therefore, of cost-effective screening strategies...