Tabassome Simon

Summary

Country: France

Publications

  1. ncbi Clinical events as a function of proton pump inhibitor use, clopidogrel use, and cytochrome P450 2C19 genotype in a large nationwide cohort of acute myocardial infarction: results from the French Registry of Acute ST-Elevation and Non-ST-Elevation Myocard
    Tabassome Simon
    Department of Pharmacology, Clinical Research Unit, APHP, St Antoine Hospital, UMPC Paris 06 University, 27 rue Chaligny, Paris, France
    Circulation 123:474-82. 2011
  2. ncbi [Impact of genetic polymorphisms in the clinical response of oral inhibitors of the platelet P2Y12 adenosine diphosphate (ADP) receptor]
    T Simon
    Service de Pharmacologie, Universite Pierre et Marie Curie Paris 6, Assistance Publique Hopitaux de Paris, France
    Ann Cardiol Angeiol (Paris) 59:S42-6. 2010
  3. ncbi Effect of paraoxonase-1 polymorphism on clinical outcomes in patients treated with clopidogrel after an acute myocardial infarction
    T Simon
    Assistance Publique Hopitaux de Paris APHP, Hopital St Antoine, URC EST, Paris, France
    Clin Pharmacol Ther 90:561-7. 2011
  4. ncbi Genetic determinants of response to clopidogrel and cardiovascular events
    Tabassome Simon
    Assistance Publique Hopitaux de Paris, Hopital Saint Antoine, and Universite Pierre et Marie Curie, Paris 06, France
    N Engl J Med 360:363-75. 2009
  5. ncbi Comparison of efficacy and safety of a standard versus a loading dose of clopidogrel for acute myocardial infarction in patients ? 75 years of age (from the FAST-MI registry)
    Etienne Puymirat
    Division of Coronary Artery Disease and Intensive Cardiac Care, Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Paris, France
    Am J Cardiol 108:755-9. 2011
  6. ncbi Association of menopause and hormone replacement therapy with large artery remodeling
    Anne Gompel
    Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Hotel Dieu, Paris, France
    Fertil Steril 96:1445-50. 2011
  7. ncbi Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study
    Laurent Beaugerie
    Department of Gastroenterology, Assistance Publique Hopitaux de Paris AP HP, Hopital Saint Antoine, Universite Pierre et Marie Curie Paris VI, Paris, France
    Lancet 374:1617-25. 2009
  8. ncbi Impact of age and gender on in-hospital and late mortality after acute myocardial infarction: increased early risk in younger women: results from the French nation-wide USIC registries
    Tabassome Simon
    Department of Pharmacology, Saint Antoine, Pierre et Marie Curie University, 27 rue Chaligny, 75012 AP HP, and Department of Cardiology, Hopital Europeen Georges Pompidou, Paris, France
    Eur Heart J 27:1282-8. 2006
  9. ncbi Comparison of thrombolysis followed by broad use of percutaneous coronary intervention with primary percutaneous coronary intervention for ST-segment-elevation acute myocardial infarction: data from the french registry on acute ST-elevation myocardial inf
    Nicolas Danchin
    Division of Coronary Artery Disease and Intensive Cardiac Care, Hopital Europeen Georges Pompidou, Assistance Publique des Hôpitaux de Paris and Faculté René Descartes, Universite Paris 5, 20 rue Leblanc, 75015 Paris, France
    Circulation 118:268-76. 2008
  10. ncbi Non-interventional research and usual care: definition, regulatory aspects, difficulties and recommendations
    Francois Lemaire
    Medical Intensive Care, Henri Mondor Hospital, Creteil, France
    Therapie 63:103-6, 97-101. 2008

Detail Information

Publications20

  1. ncbi Clinical events as a function of proton pump inhibitor use, clopidogrel use, and cytochrome P450 2C19 genotype in a large nationwide cohort of acute myocardial infarction: results from the French Registry of Acute ST-Elevation and Non-ST-Elevation Myocard
    Tabassome Simon
    Department of Pharmacology, Clinical Research Unit, APHP, St Antoine Hospital, UMPC Paris 06 University, 27 rue Chaligny, Paris, France
    Circulation 123:474-82. 2011
    ..This analysis compares treatment outcomes for patients in the French Registry of Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) who did or did not receive clopidogrel and/or PPIs...
  2. ncbi [Impact of genetic polymorphisms in the clinical response of oral inhibitors of the platelet P2Y12 adenosine diphosphate (ADP) receptor]
    T Simon
    Service de Pharmacologie, Universite Pierre et Marie Curie Paris 6, Assistance Publique Hopitaux de Paris, France
    Ann Cardiol Angeiol (Paris) 59:S42-6. 2010
    ..This article reviews the role of genetic polymorphisms in the clinical impact of oral inhibitors of the platelet P2Y12 adenosine diphosphate (ADP) receptor...
  3. ncbi Effect of paraoxonase-1 polymorphism on clinical outcomes in patients treated with clopidogrel after an acute myocardial infarction
    T Simon
    Assistance Publique Hopitaux de Paris APHP, Hopital St Antoine, URC EST, Paris, France
    Clin Pharmacol Ther 90:561-7. 2011
    ..87, 95% CI 2.52-18.72 and adjusted HR 3.06, 95% CI 1.47-6.41). Unlike CYP2C19 polymorphism, PON1 (Q192R) polymorphism is not a major pharmacogenetic contributor of clinical response to clopidogrel in AMI patients...
  4. ncbi Genetic determinants of response to clopidogrel and cardiovascular events
    Tabassome Simon
    Assistance Publique Hopitaux de Paris, Hopital Saint Antoine, and Universite Pierre et Marie Curie, Paris 06, France
    N Engl J Med 360:363-75. 2009
    ..The effect of these determinants on clinical outcomes after an acute myocardial infarction is unknown...
  5. ncbi Comparison of efficacy and safety of a standard versus a loading dose of clopidogrel for acute myocardial infarction in patients ? 75 years of age (from the FAST-MI registry)
    Etienne Puymirat
    Division of Coronary Artery Disease and Intensive Cardiac Care, Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Paris, France
    Am J Cardiol 108:755-9. 2011
    ..Large-scale randomized trials are still needed to identify the optimal LD of clopidogrel for elderly patients admitted for AMI...
  6. ncbi Association of menopause and hormone replacement therapy with large artery remodeling
    Anne Gompel
    Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Hotel Dieu, Paris, France
    Fertil Steril 96:1445-50. 2011
    ..To evaluate the remodeling of large arteries according to age at menopause, duration of menopause, and use of hormone therapy (HT)...
  7. ncbi Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study
    Laurent Beaugerie
    Department of Gastroenterology, Assistance Publique Hopitaux de Paris AP HP, Hopital Saint Antoine, Universite Pierre et Marie Curie Paris VI, Paris, France
    Lancet 374:1617-25. 2009
    ..Reports of an increased risk of lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease are controversial. We assessed this risk in a prospective observational cohort study...
  8. ncbi Impact of age and gender on in-hospital and late mortality after acute myocardial infarction: increased early risk in younger women: results from the French nation-wide USIC registries
    Tabassome Simon
    Department of Pharmacology, Saint Antoine, Pierre et Marie Curie University, 27 rue Chaligny, 75012 AP HP, and Department of Cardiology, Hopital Europeen Georges Pompidou, Paris, France
    Eur Heart J 27:1282-8. 2006
    ..To determine whether sex differences of in-hospital and after-discharge mortality differ according to the age...
  9. ncbi Comparison of thrombolysis followed by broad use of percutaneous coronary intervention with primary percutaneous coronary intervention for ST-segment-elevation acute myocardial infarction: data from the french registry on acute ST-elevation myocardial inf
    Nicolas Danchin
    Division of Coronary Artery Disease and Intensive Cardiac Care, Hopital Europeen Georges Pompidou, Assistance Publique des Hôpitaux de Paris and Faculté René Descartes, Universite Paris 5, 20 rue Leblanc, 75015 Paris, France
    Circulation 118:268-76. 2008
    ....
  10. ncbi Non-interventional research and usual care: definition, regulatory aspects, difficulties and recommendations
    Francois Lemaire
    Medical Intensive Care, Henri Mondor Hospital, Creteil, France
    Therapie 63:103-6, 97-101. 2008
    ....
  11. ncbi [Genetic polymorphism of beta-adrenergic receptors and mortality in ischemic heart disease]
    Patrice Jaillon
    Service de Pharmacologie, Hôpital Saint Antoine AP HP et Faculté de Médecine Pierre et Marie Curie, Universite Paris VI, Paris, France
    Therapie 62:1-7. 2007
    ..These data suggest that B2AR genetic polymorphism should be systematically studied in clinical trials in myocardial ischemia, with or without congestive heart failure...
  12. ncbi Comparison of routine and on-demand prescription of chest radiographs in mechanically ventilated adults: a multicentre, cluster-randomised, two-period crossover study
    Gilles Hejblum
    U707, Institut National de la Sante et de la Recherche Medicale, Paris, France
    Lancet 374:1687-93. 2009
    ..By comparison between routine and on-demand strategies, we aimed to establish which strategy was more efficient and effective for optimum patient care...
  13. ncbi Selection of intensive care unit admission criteria for patients aged 80 years and over and compliance of emergency and intensive care unit physicians with the selected criteria: An observational, multicenter, prospective study
    Maite Garrouste-Orgeas
    Saint Joseph Hospital Network, Medical Chirurgical ICU, Paris, France
    Crit Care Med 37:2919-28. 2009
    ..To describe intensive care unit referral decisions by emergency room physicians in patients aged > or =80 yrs...
  14. ncbi Effect of two oral doses of 17beta-estradiol associated with dydrogesterone on thrombin generation in healthy menopausal women: a randomized double-blind placebo-controlled study
    Alexandra Rousseau
    Department of Clinical Pharmacology, APHP, Saint Antoine Hospital, Paris University, France
    Fundam Clin Pharmacol 24:239-45. 2010
    ..The two doses of 17beta-estradiol induced in a similar degree an acceleration of the initiation and propagation phase of tissue factor triggered thrombin generation and a significant increase of FVII coagulant activity...
  15. ncbi Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6C(hi) and Ly6C(lo) monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice
    Christophe Combadiere
    Institut National de la Sante et de la Recherche Medicale, Unit 543, Universite Pierre et Marie Curie, Paris 6, Paris, France
    Circulation 117:1649-57. 2008
    ..Evidence that particular chemokine pathways may cooperate to promote monocyte accumulation into inflamed tissues, particularly atherosclerotic arteries, is still lacking...
  16. ncbi Impact of early statin therapy on development of atrial fibrillation at the acute stage of myocardial infarction: data from the FAST-MI register
    Nicolas Danchin
    Cardiology Department, Hoˆpital Europe en Georges Pompidou and Universite Paris Descartes, Paris, France
    Heart 96:1809-14. 2010
    ..The aim of this study was to determine correlations between early statin therapy and atrial fibrillation in acute myocardial infarction...
  17. ncbi Impact of age and gender interaction on circulating endothelial progenitor cells in healthy subjects
    Alexandra Rousseau
    Clinical Research Unit URC EST and Department of Pharmacology, AP HP, Saint Antoine Hospital, Universite Pierre et Marie Curie Paris 6, Paris, France
    Fertil Steril 93:843-6. 2010
    ..To assess the level of circulating endothelial progenitor cells (CEPC) in cycling women compared with men and menopausal women...
  18. ncbi Circulating secretory phospholipase A2 activity and risk of incident coronary events in healthy men and women: the EPIC-Norfolk study
    Ziad Mallat
    INSERM U689, Centre de Recherché Cardiovasculaire Lariboisière, Paris, France
    Arterioscler Thromb Vasc Biol 27:1177-83. 2007
    ..To assess the association between secretory phospholipase A2 (sPLA2) activity, which encompasses several types of sPLA2, and cardiovascular disease (CAD) in healthy individuals...
  19. ncbi Influence of pravastatin on carotid artery structure and function in dyslipidemic HIV-infected patients receiving antiretroviral therapy
    Franck Boccara
    Department of Pharmacology, , , INSERM 652, , Paris, France
    AIDS 20:2395-8. 2006
    ..Age and body mass index were independent determinants of IMT of the CCA. Mean arterial pressure, age, duration of HIV infection and protease inhibitor exposure determined aortic stiffness...
  20. ncbi Rationale, design and methods of the CASHMERE study
    Tabassome Simon
    Department of Pharmacology, Paris VI University, Saint Antoine University Hospital AP HP, Paris, France
    Fundam Clin Pharmacol 18:131-8. 2004
    ..The results are expected for 2007...