Research Topics
| Philippe SeguinSummaryCountry: France Publications
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Detail Information
Publications
Factors associated with multidrug-resistant bacteria in secondary peritonitis: impact on antibiotic therapyP Seguin
Service de Réanimation Chirurgicale Inserm U620, Hopital de Pontchaillou, Rennes, France
Clin Microbiol Infect 12:980-5. 2006..In conclusion, knowledge of these two factors may provide a more rational basis for selecting initial antimicrobial therapy for patients with secondary peritonitis...
Risk factors for multidrug-resistant bacteria in patients with post-operative peritonitis requiring intensive carePhilippe Seguin
Service de Réanimation Chirurgicale, Universite Rennes 1, INSERM U991, Hopital de Pontchaillou, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 9, Rennes, France
J Antimicrob Chemother 65:342-6. 2010..This prospective non-interventional study investigated the risk factors for multidrug-resistant bacteria (MDRB) in patients with post-operative peritonitis (POP), to provide guidance for empirical antimicrobial therapy...
Dopexamine and norepinephrine versus epinephrine on gastric perfusion in patients with septic shock: a randomized study [NCT00134212]Philippe Seguin
Service de Réanimation Chirurgicale Inserm U620, Hopital de Pontchaillou, Universite de Rennes 1, Rennes, France
Crit Care 10:R32. 2006..The effects of these drugs on oxidative stress were also assessed...
Atrial fibrillation in trauma patients requiring intensive carePhilippe Seguin
Hopital Pontchaillou, Surgical Intensive Care Unit, 2 rue Henri Le Guilloux, Rennes Cedex 9, 35033 Rennes, France
Intensive Care Med 32:398-404. 2006..To evaluate the incidence and risk factors of atrial fibrillation (AF) in trauma patients...
[Testing nasogastric tube placement: evaluation of three different methods in intensive care unit]P Seguin
Service de Réanimation Chirurgicale, Hopital Pontchaillou, 2, rue Henri Le Guilloux, 35033 Rennes cedex 09, France
Ann Fr Anesth Reanim 24:594-9. 2005..Evaluation of three methods (aspiration of gastric fluid, pH measurement of gastric fluid, and insufflation of air) in order to determine the right position of the nasogastric (NG) tube...
Plasma and peritoneal concentration following continuous infusion of cefotaxime in patients with secondary peritonitisPhilippe Seguin
Service de Réanimation Chirurgicale Inserm U620, Universite Rennes 1, Hopital de Pontchaillou, Rennes Cedex 9, Rennes, France
J Antimicrob Chemother 63:564-7. 2009..The aim of this study was to determine the steady-state plasma and peritoneal concentrations of cefotaxime and its metabolite desacetyl-cefotaxime administered by continuous infusion to critically ill patients with secondary peritonitis...
Effectiveness of simple daily sensitization of physicians to the duration of central venous and urinary tract catheterizationPhilippe Seguin
Service de Réanimation Chirurgicale, INSERM U991, Universite Rennes 1, Hopital de Pontchaillou, 2, rue Henri Le Guilloux, 35033, Rennes Cedex 9, France
Intensive Care Med 36:1202-6. 2010..To evaluate the effectiveness of simple daily sensitization of physicians to the duration of central venous and urinary tract catheterization, and impact on infection rates...
Atrial fibrillation is not just an artefact in the ICUPhilippe Seguin
Service d anesthésie réanimation 1, Service de Réanimation Chirurgicale, Hôpital Pontchailllou, 2 rue Henri Le Guilloux, 35033 Rennes Cedex, France
Crit Care 14:182. 2010..How such a finding could modify the therapeutic approach remains elusive. The impact of AF on mortality is not clearly demonstrated in the ICU, with AF reflecting essentially the severity of the underlying disease...
Determination of capillary hemoglobin levels using the HemoCue system in intensive care patientsPhilippe Seguin
Service de Réanimation Chirurgicale, Universite Rennes 1, INSERM U991, Hopital Pontchaillou, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 9, Rennes, France
J Crit Care 26:423-7. 2011..The study aimed to compare hemoglobin (Hb) values determined using the portable HemoCue system (HemoCue Hb 201+; HemoCue AB, Ängelholm, Sweden) with laboratory Hb level determination...
Incidence and risk factors of atrial fibrillation in a surgical intensive care unitPhilippe Seguin
Surgical Intensive Care Unit, , Rennes, France
Crit Care Med 32:722-6. 2004..Blunt thoracic trauma increases the chances of developing AF, as does the presence of shock, especially septic shock...
Effects of epinephrine compared with the combination of dobutamine and norepinephrine on gastric perfusion in septic shockPhilippe Seguin
, , 2 Rue Henri Le Gailloux, , 35033 Rennes Cedex, France
Clin Pharmacol Ther 71:381-8. 2002..This effect was probably a result of higher cardiac index...
Effect of oropharyngeal decontamination by povidone-iodine on ventilator-associated pneumonia in patients with head traumaPhilippe Seguin
Surgical Intensive Care Unit, INSERM U620, , 2 rue Henri Le Guilloux, 35033 Rennes Cedex, France
Crit Care Med 34:1514-9. 2006..CONCLUSIONS: The regular administration of povidone-iodine may be an effective strategy for decreasing the prevalence of ventilator-associated pneumonia in patients with severe head trauma...
[Activated protein C treatment: experience about 23 patients in the operative period]A Maurice
Service de Réanimation Chirurgicale, CHU Pontchaillou, 2, rue Henri Le Guillou, 35033 Rennes cedex 09, France
Ann Fr Anesth Reanim 24:343-6. 2005..To evaluate the use of activated C protein (ACP) in a Surgical Intensive Care Unit...
Cerebral Microdialysis Effects of Propofol versus Midazolam in Severe Traumatic Brain InjuryMichèle Tanguy
1 Département d Anesthésie Réanimation 1, Hopital de Pontchaillou, Cedex, France
J Neurotrauma 29:1105-10. 2012..308), or glucose (time effect p=0.116, treatment effect p=0.088, time×treatment interaction p=0.235). These results do not support a difference between propofol and midazolam for sedation for the cerebral metabolic profile in severe TBI...
The effects of small-dose ketamine on morphine consumption in surgical intensive care unit patients after major abdominal surgeryNicolas Guillou
Surgical Intensive Care Unit, , Rennes, France
Anesth Analg 97:843-7. 2003..05). We concluded that small doses of ketamine were a valuable adjunct to opioids in surgical intensive care unit patients after major abdominal surgery...
Clinical review: fever in septic ICU patients--friend or foe?Yoann Launey
Service d anesthésie réanimation 1, Hopital Pontchaillou, 2 rue Henri Le Guilloux, 35000 Rennes, France
Crit Care 15:222. 2011..Finally, the treatment of fever by pharmacological and/or physical means is discussed with regards to their drawbacks, which argues for their careful use in septic patients in the absence of clinical relevance...
Estimation of the diameter and cross-sectional area of the internal jugular veins in adult patientsDéborah Tartière
Service d anesthésie réanimation 1, Universite de Rennes 1, Hopital Pontchaillou, 2 rue Henri Le Guilloux, 35000 Rennes, France
Crit Care 13:R197. 2009....
Catecholamines induce an inflammatory response in human hepatocytesCaroline Aninat
INSERM U620, Universite de Rennes 1, Rennes, France
Crit Care Med 36:848-54. 2008..As a prelude to clinical application, we tested the hypothesis that catecholamines could modulate the lipopolysaccharide-induced inflammatory response and function in human liver...
Effects of price information on test ordering in an intensive care unitPhilippe Seguin
Service d Anesthésie Réanimation Chirurgicale 1, rue Henri Le Guilloux, Hopital de Pontchaillou, 35033 Rennes Cedex, France
Intensive Care Med 28:332-5. 2002..To determine if daily information on the price of common laboratory tests and chest X-ray could significantly influence test ordering by physicians and decrease the costs...
Evaluation of a new semi-continuous cardiac output system in the intensive care unitP Seguin
Service d Anesthesiologie Réanimation Chirurgicale 1, CHR U de Pontchaillou, Rennes, France
Can J Anaesth 45:578-83. 1998..The aim of this study was to compare the accuracy and reproducibility of this new device with conventional ice-bolus thermodilution cardiac output (BCO)...
Evidence for the need of bedside accuracy of pulse oximetry in an intensive care unitP Seguin
Service de Réanimation Chirurgicale, CHRU de Pontchaillou, Rennes, France
Crit Care Med 28:703-6. 2000....
[Saccharomyces boulardii fungal sepsis: beware of the yeast]Sonia Piechno
Can J Anaesth 54:245-6. 2007
