Christophe Baudouin

Summary

Affiliation: rue de Charenton
Country: France

Publications

  1. ncbi In vivo confocal microscopy and ex vivo flow cytometry: new tools for assessing ocular inflammation applied to rabbit lipopolysaccharide-induced conjunctivitis
    Hong Liang
    Department of Ophthalmology, Centre Hospitalier National d Ophtalmologie des Quinze Vingts, Paris, France
    Mol Vis 12:1392-402. 2006
  2. ncbi Predictors of additional intraocular pressure reduction in patients changed to latanoprost/timolol fixed combination
    Eric Sellem
    Centre Ophtalmologique Kleber, 50, cours Franklin Roosevelt, 69006 Lyon, France
    BMC Ophthalmol 10:10. 2010
  3. ncbi First-line latanoprost therapy in ocular hypertension or open-angle glaucoma patients: a 3-month efficacy analysis stratified by initial intraocular pressure
    Philippe Denis
    Ophthalmology Department, Hopital Edouard Herriot, 5, Place d Arsonval, 690437 Lyon Cedex 03, France
    BMC Ophthalmol 10:4. 2010
  4. ncbi [New diagnosis approaches: iridocorneal angle in optical coherence tomography]
    C Baudouin
    Service d ophtalmologie III, Centre Hospitalier National d Ophtalmologie des Quinze Vingts, 28, rue de Charenton, F 75571 Paris Cedex 12, France
    J Fr Ophtalmol 32:172-5. 2009
  5. ncbi Changes in medical and surgical treatments of glaucoma between 1997 and 2000 in France
    C Baudouin
    National Hospital Center of Ophthalmology of Quinze Vingts, Paris, France
    Eur J Ophthalmol 13:S53-60. 2003
  6. ncbi Efficacy of indomethacin 0.1% and fluorometholone 0.1% on conjunctival inflammation following chronic application of antiglaucomatous drugs
    Christophe Baudouin
    Hôpital A Paré, Boulogne Billancourt, France
    Graefes Arch Clin Exp Ophthalmol 240:929-35. 2002
  7. ncbi [Current treatments of xerophthalmia in Sjögren's syndrome]
    C Baudouin
    Centre National d Ophtalmologie des Quinze Vingts, Inserm U450 UFR Paris Ouest, 28, rue de Charenton, 75012 Paris, France
    Rev Med Interne 25:376-82. 2004
  8. ncbi Severe impairment of health-related quality of life in patients suffering from ocular surface diseases
    C Baudouin
    Quinze Vingts National Ophthalmology Hospital, Paris, France
    J Fr Ophtalmol 31:369-78. 2008
  9. ncbi Conjunctival epithelial cell expression of interleukins and inflammatory markers in glaucoma patients treated over the long term
    Christophe Baudouin
    Department of Ophthalmology, Quinze Vingts National Ophthalmology Hospital, APHP, Paris Ouest School of Medicine, University of Versailles, Paris, France
    Ophthalmology 111:2186-92. 2004
  10. ncbi Detrimental effect of preservatives in eyedrops: implications for the treatment of glaucoma
    Christophe Baudouin
    Department of Ophthalmology III, Quinze Vingts National Ophthalmology Hospital, Paris, France
    Acta Ophthalmol 86:716-26. 2008

Detail Information

Publications117 found, 100 shown here

  1. ncbi In vivo confocal microscopy and ex vivo flow cytometry: new tools for assessing ocular inflammation applied to rabbit lipopolysaccharide-induced conjunctivitis
    Hong Liang
    Department of Ophthalmology, Centre Hospitalier National d Ophtalmologie des Quinze Vingts, Paris, France
    Mol Vis 12:1392-402. 2006
    ..We used in vivo confocal microscopy (CM) and ex vivo flow cytometry, two new tools for assessing ocular inflammation induced by LPS...
  2. ncbi Predictors of additional intraocular pressure reduction in patients changed to latanoprost/timolol fixed combination
    Eric Sellem
    Centre Ophtalmologique Kleber, 50, cours Franklin Roosevelt, 69006 Lyon, France
    BMC Ophthalmol 10:10. 2010
    ....
  3. ncbi First-line latanoprost therapy in ocular hypertension or open-angle glaucoma patients: a 3-month efficacy analysis stratified by initial intraocular pressure
    Philippe Denis
    Ophthalmology Department, Hopital Edouard Herriot, 5, Place d Arsonval, 690437 Lyon Cedex 03, France
    BMC Ophthalmol 10:4. 2010
    ..This study prospectively assessed the efficacy of latanoprost monotherapy in a large cohort of treatment-naive patients with a broad range of baseline intraocular pressure (IOP) levels treated in actual clinical practice settings...
  4. ncbi [New diagnosis approaches: iridocorneal angle in optical coherence tomography]
    C Baudouin
    Service d ophtalmologie III, Centre Hospitalier National d Ophtalmologie des Quinze Vingts, 28, rue de Charenton, F 75571 Paris Cedex 12, France
    J Fr Ophtalmol 32:172-5. 2009
    ..Use of OCT in glaucoma diagnosis and follow-up will increase with technical progress and new high speed ultrahigh-resolution OCT...
  5. ncbi Changes in medical and surgical treatments of glaucoma between 1997 and 2000 in France
    C Baudouin
    National Hospital Center of Ophthalmology of Quinze Vingts, Paris, France
    Eur J Ophthalmol 13:S53-60. 2003
    ..To analyze quantitative changes in glaucoma treatment strategies between 1997 and 2000 in France...
  6. ncbi Efficacy of indomethacin 0.1% and fluorometholone 0.1% on conjunctival inflammation following chronic application of antiglaucomatous drugs
    Christophe Baudouin
    Hôpital A Paré, Boulogne Billancourt, France
    Graefes Arch Clin Exp Ophthalmol 240:929-35. 2002
    ..1%) on conjunctival inflammation following chronic application of antiglaucomatous drugs, in comparison with a steroidal ophthalmic solution (preserved fluorometholone)...
  7. ncbi [Current treatments of xerophthalmia in Sjögren's syndrome]
    C Baudouin
    Centre National d Ophtalmologie des Quinze Vingts, Inserm U450 UFR Paris Ouest, 28, rue de Charenton, 75012 Paris, France
    Rev Med Interne 25:376-82. 2004
    ....
  8. ncbi Severe impairment of health-related quality of life in patients suffering from ocular surface diseases
    C Baudouin
    Quinze Vingts National Ophthalmology Hospital, Paris, France
    J Fr Ophtalmol 31:369-78. 2008
    ..To evaluate health-related quality of life (HRQoL) in French patients suffering from ocular surface diseases (OSDs)...
  9. ncbi Conjunctival epithelial cell expression of interleukins and inflammatory markers in glaucoma patients treated over the long term
    Christophe Baudouin
    Department of Ophthalmology, Quinze Vingts National Ophthalmology Hospital, APHP, Paris Ouest School of Medicine, University of Versailles, Paris, France
    Ophthalmology 111:2186-92. 2004
    ..To compare the conjunctival epithelial cell expressions of inflammatory cytokines in normal subjects and in glaucoma patients treated over the long term...
  10. ncbi Detrimental effect of preservatives in eyedrops: implications for the treatment of glaucoma
    Christophe Baudouin
    Department of Ophthalmology III, Quinze Vingts National Ophthalmology Hospital, Paris, France
    Acta Ophthalmol 86:716-26. 2008
    ..Collectively, these data suggest that preservative-free antiglaucoma treatments have clinically relevant benefits for patients...
  11. ncbi Preservatives in eyedrops: the good, the bad and the ugly
    Christophe Baudouin
    Department of Ophthalmology III, Quinze Vingts National Ophthalmology Hospital, INSERM, U968, UPMC Univ Paris 06, UMR_S 968, Institut de la Vision, CNRS, UMR_7210, Paris F 75012, France
    Prog Retin Eye Res 29:312-34. 2010
    ..Indeed, mild symptoms should not be underestimated, neglected, or denied, because they may very well be the apparent manifestations of more severe, potentially threatening subclinical reactions that may later cause major concerns...
  12. ncbi [Vaccine for glaucoma, myth or reality?]
    C Baudouin
    Service d ophtalmologie 3, Centre Hospitalier National d Ophtalmologie des Quinze Vingts, Paris
    J Fr Ophtalmol 29:9-12. 2006
    ....
  13. ncbi Allergic reaction to topical eyedrops
    Christophe Baudouin
    Department of Ophthalmology, Quinze Vingts National Ophthalmology Hospital, Paris, France
    Curr Opin Allergy Clin Immunol 5:459-63. 2005
    ..As allergy is only one possible mechanism, this review was extended to all reports or studies describing allergic, inflammatory or toxic effects related to eyedrops since 2004...
  14. ncbi CCR 4 and CCR 5 expression in conjunctival specimens as differential markers of T(H)1/ T(H)2 in ocular surface disorders
    Christophe Baudouin
    Department of Ophthalmology, Quinze Vingts National Ophthalmology Hospital and Ambroise Paré Hospital, APHP, Paris Ouest School of Medicine, University of Versailles, Paris, France
    J Allergy Clin Immunol 116:614-9. 2005
    ..Accurate inflammatory mechanisms in chronic ocular surface diseases (OSDs) cannot routinely be assessed. New techniques for investigating ocular surface inflammatory pathways are of major importance...
  15. ncbi The ocular surface of glaucoma patients treated over the long term expresses inflammatory markers related to both T-helper 1 and T-helper 2 pathways
    Christophe Baudouin
    Department of Ophthalmology, Quinze Vingts National Ophthalmology Hospital and Ambroise Paré Hospital, APHP, Paris Ouest School of Medicine, University of Versailles, Versailles, France
    Ophthalmology 115:109-15. 2008
    ....
  16. ncbi In vitro effects of preservative-free tafluprost and preserved latanoprost, travoprost, and bimatoprost in a conjunctival epithelial cell line
    Emmanuelle Brasnu
    Department of Ophthalmology III, Quinze Vingts National Ophthalmology Hospital, Paris, France
    Curr Eye Res 33:303-12. 2008
    ....
  17. ncbi Conjunctival proinflammatory and proapoptotic effects of latanoprost and preserved and unpreserved timolol: an ex vivo and in vitro study
    Pierre-Jean Pisella
    Department of Ophthalmology, University Hospital of Tours, Tours, France
    Invest Ophthalmol Vis Sci 45:1360-8. 2004
    ..These results suggest a potential protective effect of the prostaglandin analogue and to a lesser extent of timolol against the toxicity of BAC in conjunctival cells...
  18. ncbi In vitro study of inflammatory potential and toxicity profile of latanoprost, travoprost, and bimatoprost in conjunctiva-derived epithelial cells
    Jean-Marc Guenoun
    Department of Ophthalmology, Quinze-Vingts National Ophthalmology Hospital, Paris, France
    Invest Ophthalmol Vis Sci 46:2444-50. 2005
    ....
  19. ncbi In vitro studies of antiglaucomatous prostaglandin analogues: travoprost with and without benzalkonium chloride and preserved latanoprost
    Christophe Baudouin
    Department of Ophthalmology 3, Quinze Vingts National Ophthalmology Hospital, Paris, France
    Invest Ophthalmol Vis Sci 48:4123-8. 2007
    ..004% containing 0.015% benzalkonium chloride (BAK), travoprost Z 0.004%, a new formulation without BAK, and latanoprost 0.005% containing 0.02% BAK...
  20. ncbi Comparative study of topical anti-allergic eye drops on human conjunctiva-derived cells: responses to histamine and IFN gamma and toxicological profiles
    Aude Pauly
    U598, INSERM, Cordeliers Biomedical Institute, 15 rue de l Ecole de Medecine, 75006, Paris, France
    Graefes Arch Clin Exp Ophthalmol 245:534-46. 2007
    ..The purpose of the study was to compare toxic effects and responses to histamine and IFN gamma associated with the use of some widely used anti-allergic eye drops commercially available today...
  21. ncbi New tools for the evaluation of toxic ocular surface changes in the rat
    Aude Pauly
    INSERM Institut National de la Santé et de la Recherche Médicale U598, Cordeliers Biomedical Institute, University of Paris 5, Paris, France
    Invest Ophthalmol Vis Sci 48:5473-83. 2007
    ..To assess the usefulness of noninvasive combined technologies used to observe ocular surface changes in toxicology studies...
  22. ncbi Comparative in vitro toxicology study of travoprost polyquad-preserved, travoprost BAK-preserved, and latanoprost BAK-preserved ophthalmic solutions on human conjunctival epithelial cells
    Francoise Brignole-Baudouin
    Paris, France
    Curr Eye Res 36:979-88. 2011
    ..004% ophthalmic solution (travoprost BAK) and BAK-preserved latanoprost 0.005% ophthalmic solution (latanoprost BAK)...
  23. ncbi LPS-stimulated inflammation and apoptosis in corneal injury models
    Hong Liang
    Department of Ophthalmology III, Quinze Vingts National Ophthalmology Hospital, APHP, University of Versailles, Paris, France
    Mol Vis 13:1169-80. 2007
    ..To evaluate and compare the proinflammatory and apoptotic effects of lipopolysaccharide (LPS) in three rabbit corneal injury models using a new in vivo confocal microscope (IVCM) and immunohistological techniques...
  24. ncbi Polyquad-preserved travoprost/timolol, benzalkonium chloride (BAK)-preserved travoprost/timolol, and latanoprost/timolol in fixed combinations: a rabbit ocular surface study
    Hong Liang
    INSERM, UMR_S, Paris, France
    Adv Ther 28:311-25. 2011
    ..004%/timolol 0.5% ophthalmic solution and latanoprost 0.005%/timolol 0.5% ophthalmic solution, which both contain the preservative benzalkonium chloride (BAK)...
  25. ncbi In vitro comparative toxicology of polyquad-preserved and benzalkonium chloride-preserved travoprost/timolol fixed combination and latanoprost/timolol fixed combination
    Francoise Brignole-Baudouin
    Institut National de la Sante et de la Recherche Medicale, U968, Paris, France
    J Ocul Pharmacol Ther 27:273-80. 2011
    ..5% fixed combination ophthalmic solution (travoprost/timolol BAK), (2) commercially available latanoprost 0.005%/timolol 0.5% fixed combination ophthalmic solution (latanoprost/timolol BAK), and (3) their associated BAK concentrations...
  26. ncbi Th1 and Th2 responses on the ocular surface in uveitis identified by CCR4 and CCR5 conjunctival expression
    Liem Trinh
    Department of Ophthalmology III, Quinze Vingts National Ophthalmology Hospital, Paris, France
    Am J Ophthalmol 144:580-5. 2007
    ....
  27. ncbi Live conjunctiva-associated lymphoid tissue analysis in rabbit under inflammatory stimuli using in vivo confocal microscopy
    Hong Liang
    Department of Toxicology, Faculty of Biological and Pharmacological Sciences, Paris Descartes University, Paris, France
    Invest Ophthalmol Vis Sci 51:1008-15. 2010
    ..The authors investigated in rabbit eyes the cell reactions occurring in the organized CALT during conjunctival inflammation models...
  28. ncbi Filtering blebs and aqueous pathway an immunocytological and in vivo confocal microscopy study
    Nawel Amar
    Department of Ophthalmology III, Quinze Vingts National Ophthalmology Hospital, Paris, France
    Ophthalmology 115:1154-1161.e4. 2008
    ..To characterize and understand, at the cellular level, the aqueous humor pathways after filtering surgery, using in vivo confocal microscopy and impression cytology (IC)...
  29. ncbi Th1- and Th2-related chemokine and chemokine receptor expression on the ocular surface in endotoxin-induced uveitis
    Liem Trinh
    Department of Ophthalmology III, Quinze Vingts National Ophthalmology Hospital, Paris, France
    Mol Vis 14:2428-34. 2008
    ....
  30. ncbi In vitro effects of preserved and unpreserved antiglaucoma drugs on apoptotic marker expression by human trabecular cells
    Pascale Hamard
    Department of Ophthalmology, Quinze Vingts Hospital, 28 rue de Charenton, 75012 Paris, France
    Graefes Arch Clin Exp Ophthalmol 241:1037-43. 2003
    ....
  31. ncbi The corneal endothelium in an endotoxin-induced uveitis model: correlation between in vivo confocal microscopy and immunohistochemistry
    Liem Trinh
    Department of Ophthalmology III, Quinze Vingts National Ophthalmology Hospital, Paris, France
    Mol Vis 14:1149-56. 2008
    ..In vivo confocal microscopy images were correlated with ex vivo immunostaining of corneal endothelium from rat eyes with endotoxin-induced uveitis (EIU)...
  32. ncbi Toxicological evaluation of preservative-containing and preservative-free topical prostaglandin analogues on a three-dimensional-reconstituted corneal epithelium system
    Hong Liang
    Department of Ophthalmology III, Quinze Vingts National Ophthalmology Hospital, Paris, France
    Br J Ophthalmol 95:869-75. 2011
    ..005% latanoprost, 0.004% travoprost, 0.03% bimatoprost containing 0.02%, 0.015% and 0.005% BAC, respectively, and the preservative-free (PF) tafluprost. Solutions of 0.01% and 0.02% BAC alone were also evaluated for comparison...
  33. ncbi Comparison of the ocular tolerability of a latanoprost cationic emulsion versus conventional formulations of prostaglandins: an in vivo toxicity assay
    Hong Liang
    Paris Descartes University, Faculty of Biological and Pharmacological Sciences, Department of Toxicology, Paris, France
    Mol Vis 15:1690-9. 2009
    ..005% latanoprost, 0.004% travoprost, 0.03% bimatoprost (containing 0.02%, 0.015%, and 0.005% BAC, respectively), and 0.005% latanoprost in a new cationic emulsion (LCEm) formulation...
  34. ncbi Multiple endpoint analysis of the 3D-reconstituted corneal epithelium after treatment with benzalkonium chloride: early detection of toxic damage
    Aude Pauly
    University of Pierre et Marie Curie Paris 6, UMR S592, Paris, France
    Invest Ophthalmol Vis Sci 50:1644-52. 2009
    ..To investigate the effects of benzalkonium chloride (BAK) on the human reconstituted corneal epithelial model (HCE) and to optimize the operating potential of this model in the field of ophthalmic toxicology...
  35. ncbi Effects of toxic cellular stresses and divalent cations on the human P2X7 cell death receptor
    Mélody Dutot
    Laboratoire de Toxicologie, Faculte des Sciences Pharmaceutiques et Biologiques, Universite Paris Descartes, Paris, France
    Mol Vis 14:889-97. 2008
    ..The purpose of this study was to investigate responses to toxic cellular stresses in different human ocular epithelia...
  36. ncbi Spectrofluorometry assays for oxidative stress and apoptosis, with cell viability on the same microplates: a multiparametric analysis and quality control
    Chadi Mehanna
    Institut de la Vision, UMR S968, UPMC University of Pierre and Marie Curie, Paris, France
    Toxicol In Vitro 25:1089-96. 2011
    ..Thus, it is possible and recommended to perform NR assays on the same microplates as the other assays. This double staining procedure could constitute a quality control procedure and would allow multiparametric analysis...
  37. ncbi A multicentre, double-masked, randomized, controlled trial assessing the effect of oral supplementation of omega-3 and omega-6 fatty acids on a conjunctival inflammatory marker in dry eye patients
    Francoise Brignole-Baudouin
    Department of Toxicology, Paris Descartes University, Paris, France
    Acta Ophthalmol 89:e591-7. 2011
    ..To determine whether oral supplementation with omega-3 and omega-6 fatty acids can reduce conjunctival epithelium expression of the inflammatory marker human leucocyte antigen-DR (HLA-DR) in patients with dry eye syndrome (DES)...
  38. ncbi An in vivo confocal microscopy and impression cytology evaluation of pterygium activity
    Antoine Labbe
    Department of Ophthalmology 3, Quinze Vingts National Ophthalmology Hospital, 28 rue de Charenton, Paris, France
    Cornea 29:392-9. 2010
    ..To correlate pterygium activity with in vivo confocal microscopy (IVCM) and ex vivo impression cytology (IC) analyses...
  39. ncbi Modifications in corneal biomechanics and intraocular pressure after deep sclerectomy
    Vasiliki Iordanidou
    Department of Ophthalmology, Quinze Vingts National Ophthalmology Hospital, 28 rue de Charenton, Paris Cedex 12, France
    J Glaucoma 19:252-6. 2010
    ....
  40. ncbi In vivo confocal microscopy and anterior segment optical coherence tomography analysis of the cornea in nephropathic cystinosis
    Antoine Labbe
    Department of Ophthalmology III, Quinze Vingts National Ophthalmology Hospital, 28 rue de Charenton, Paris, France
    Ophthalmology 116:870-6. 2009
    ..To analyze the corneas of patients with nephropathic cystinosis using in vivo confocal microscopy (IVCM) and anterior segment optical coherence tomography (AS-OCT)...
  41. ncbi Flow cytometric analysis of the inflammatory marker HLA DR in dry eye syndrome: results from 12 months of randomized treatment with topical cyclosporin A
    Christophe Baudouin
    Department of Ophthalmology, , University of Paris V, France
    Adv Exp Med Biol 506:761-9. 2002
  42. ncbi In vivo corneal confocal microscopy in marfan syndrome
    Vasiliki Iordanidou
    Department of Ophthalmology III, Quinze Vingts National Ophthalmology Hospital, Paris, France
    Cornea 26:787-92. 2007
    ..To examine the cornea of patients with Marfan syndrome in comparison with a control group by using the in vivo confocal microscope...
  43. ncbi Contribution of in vivo confocal microscopy to the diagnosis and management of infectious keratitis
    Antoine Labbe
    Department of Ophthalmology III, Quinze Vingts National Ophthalmology Hospital, Paris, France
    Ocul Surf 7:41-52. 2009
    ..By providing in vivo, repeated, and noninvasive analyses of the cornea, IVCM may also be used to evaluate the effectiveness of treatment and the healing of the cornea in the follow-up of infectious keratitis patients...
  44. ncbi In vivo corneal confocal microscopy comparison of intralase femtosecond laser and mechanical microkeratome for laser in situ keratomileusis
    Bertrand Sonigo
    Department of Ophthalmology III, Quinze-Vingts National Ophthalmology Hospital, Paris, and Assistance Publique des Hopitaux de Paris, School of Medicine, University of Versailles, France
    Invest Ophthalmol Vis Sci 47:2803-11. 2006
    ..However, the IntraLase flap margin showed greater fibrotic scarring than that induced by the mechanical microkeratome...
  45. ncbi In vitro interactions between peripheral blood lymphocytes and the Wong-Kilbourne derivative of Chang conjunctival cells
    Alexis Chassignol
    Department of Ophthalmology III, Quinze Vingts National Ophthalmology Hospital, Paris, France
    Invest Ophthalmol Vis Sci 53:1492-8. 2012
    ..To investigate the interactions between conjunctival cells and peripheral blood lymphocytes (PBLs) in vitro and to analyze the role of benzalkonium chloride (BAC)-induced apoptosis in this model...
  46. ncbi Cytoprotective effects of hyaluronic acid and Carbomer 934P in ocular surface epithelial cells
    Caroline Debbasch
    Cellular Pharmacotoxicology Unit, Toxicology Laboratory, Quinze-Vingts, National Hospital Center for Ophthalmology, , University of Paris-V, Paris, France
    Invest Ophthalmol Vis Sci 43:3409-15. 2002
    ..These results may allow use of hydrogels, not only in dry eye but also in ocular surface disorders involving oxidative stress and in ophthalmic drug therapy to improve ocular tolerance...
  47. ncbi Short-term comparative study of topical 2% carteolol with and without benzalkonium chloride in healthy volunteers
    C Baudouin
    Department of Ophthalmology, Ambroise Paré, University of Paris V René Descartes, France
    Br J Ophthalmol 82:39-42. 1998
    ..A crossover, randomised double blind study was undertaken in 30 healthy volunteers, in order to compare the tolerance of 2% carteolol with and without preservative in short term use...
  48. ncbi [A new approach for better comprehension of diseases of the ocular surface]
    C Baudouin
    Centre National d Ophtalmologie des Quinze Vingts, Paris, France
    J Fr Ophtalmol 30:239-46. 2007
    ....
  49. ncbi Flow cytometric analysis of inflammatory markers in KCS: 6-month treatment with topical cyclosporin A
    F Brignole
    Laboratory of Immunohematology and the. Department of Ophthalmology, , APHP, , Boulogne, France
    Invest Ophthalmol Vis Sci 42:90-5. 2001
    ..This study confirms that cyclosporin A may be efficient in reducing conjunctival inflammation in moderate to severe KCS and is consistent with clinical results in this indication...
  50. ncbi Comparison of the effects of preserved and unpreserved formulations of timolol on the ocular surface of albino rabbits
    P J Pisella
    Department of Ophthalmology, Ambroise Pare Hospital, APHP, and Toxicology Laboratory, University of Paris V René Descartes, Paris, France
    Ophthalmic Res 32:3-8. 2000
    ..This study confirms that using unpreserved timolol may be beneficial for the long-term treatment of glaucomatous patients as it increases tear film stability and decreases epithelial permeability and stromal aggression of the cornea...
  51. ncbi Conjunctiva-associated lymphoid tissue (CALT) reactions to antiglaucoma prostaglandins with or without BAK-preservative in rabbit acute toxicity study
    Hong Liang
    INSERM, U968, Paris, France
    PLoS ONE 7:e33913. 2012
    ..IVCM-CALT analysis could be a pertinent tool in the future for understanding the immunotoxicologic challenges in the ocular surface and would provide useful criteria for evaluating newly developed eye drops...
  52. ncbi Measurement of health-related quality of life with glaucoma: validation of the Glau-QoL 36-item questionnaire
    Alain Béchetoille
    Ophthalmological Practice, Paris, France
    Acta Ophthalmol 86:71-80. 2008
    ..To validate a glaucoma-specific health-related quality of life (HRQoL) questionnaire: the Glau-QoL...
  53. ncbi In vivo architectural analysis of clear corneal incisions using anterior segment optical coherence tomography
    Sylvère Dupont-Monod
    Centre Hospitalier National d Ophtalmologie des Quinze Vingts, Universite Paris Descartes, Assistance Publique des Hopitaux de Paris, Hopital Hotel Dieu, Paris, France
    J Cataract Refract Surg 35:444-50. 2009
    ..To use anterior segment optical coherence tomography (AS-OCT) to analyze the in vivo architecture of clear corneal incisions after phacoemulsification using different techniques...
  54. ncbi In vitro effects of preserved or preservative-free antiglaucoma medications on human complement system
    Catherine Blondin
    Department of Ophthalmology, Quinze Vingts National Hospital, Paris, France
    Curr Eye Res 27:253-9. 2003
    ..However, the underlying mechanisms are still poorly understood. The aim of this study was to assess the effects of antiglaucoma medications on the complement system, an early mediator of the inflammatory response...
  55. ncbi Xal-Ease: impact of an ocular hypotensive delivery device on ease of eyedrop administration, patient compliance, and satisfaction
    Jean Philippe Nordmann
    Hôpital des Quinze Vingts, Paris France
    Eur J Ophthalmol 19:949-56. 2009
    ..To measure the impact of the Xal-Ease delivery device on ease of eyedrop administration and on treatment compliance and satisfaction...
  56. ncbi [Heavy silicone oil as internal tamponade for retinal detachment: efficacy and tolerance]
    S Scheer
    centre hospitalier national d ophtalmologie des XV XX, Paris
    J Fr Ophtalmol 29:129-35. 2006
    ..To evaluate the tolerance and efficacy of heavy silicone oil as internal tamponade for retinal detachment surgery...
  57. ncbi Confocal microscopic examination of trabecular meshwork removed during ab externo trabeculectomy
    P Hamard
    Department of Ophthalmology, Quinze Vingts Hospital Paris, University Paris V, France
    Br J Ophthalmol 86:1046-52. 2002
    ..ETM characteristics were evaluated with a confocal microscope...
  58. ncbi [The Video Tearscope: a new method for evaluating lacrimal film in vivo]
    Y Ounnoughene
    Service d Ophtalmologie, Hopital Ambroise Pare, AP HP, Boulogne, UFR Paris Ile de France Ouest et Centre National Hospitalier des Quinze vingts, Paris
    J Fr Ophtalmol 29:476-84. 2006
    ..We studied the blinking types and LFST using the Vi-Te technique. The analysis was carried out at 25 images/s, corresponding to an in-between image interval of 40 ms...
  59. ncbi [Human trabecular cells and apoptosis: in vitro evaluation of the effect of betaxolol with or without preservative]
    P Hamard
    Services d Ophtalmologie, C H N O des Quinze Vingts, Paris et Hôpital Ambroise Paré, APHP, Boulogne, France
    J Fr Ophtalmol 25:777-84. 2002
    ..On a human cultured trabecular cell line, we investigated the potential proapoptotic effect of a beta-blocker with or without preservative, benzalkonium chloride (0.01% BAC), by flow cytometry and confocal microscopy...
  60. ncbi Conjunctival and corneal reactions in rabbits following short- and repeated exposure to preservative-free tafluprost, commercially available latanoprost and 0.02% benzalkonium chloride
    H Liang
    Department of Toxicology, Faculty of Biological and Pharmacological Sciences, University Paris Descartes, Paris, France
    Br J Ophthalmol 92:1275-82. 2008
    ..To compare the conjunctival and corneal reactions of commercially available solution of latanoprost (Xalatan) and preservative-free (PF) tafluprost in rabbits...
  61. ncbi [Contribution of intravitreal infracyanine green to macular hole and epimacular membrane surgery: preliminary study]
    M Ullern
    CHNO Quinze-Vingts, 28, rue de Charenton, Paris 75012, France
    J Fr Ophtalmol 25:915-20. 2002
    ..A good correlation was found between surgical and histopathological aspects. CONCLUSION: Intravitreal infracyanine green is very helpful for the removal of internal limiting membrane in macular holes and epiretinal membrane surgery...
  62. ncbi Toxicity of preserved and unpreserved antiglaucoma topical drugs in an in vitro model of conjunctival cells
    M De Saint Jean
    Department of Ophthalmology, University Paris 5, Ambroise Pare Hospital, Boulogne, France
    Curr Eye Res 20:85-94. 2000
    ..To compare the toxicity of a short-time application of timolol with benzalkonium chloride (timolol-BAC+) and unpreserved timolol (timolol-BAC-) in a human conjunctival cell line...
  63. ncbi [Molteno implant and refractory glaucoma. Evaluation of postoperative IOP control and complications with a modified surgical procedure]
    P Hamard
    Service d Ophtalmologie, Centre Hospitalier National d Ophtalmologie des Quinze Vingts, 28, rue de Charenton, 75012 Paris, France
    J Fr Ophtalmol 26:15-23. 2003
    ..However, tube occlusion may lead to transient postoperative hypertony. Our retrospective study reports on double-plate Molteno implantation with intraoperative external tube occlusion associated with trabeculectomy in some cases...
  64. ncbi [Conditions bordering on allergy]
    C Baudouin
    Centre Hospitalier National d Ophtalmologie des Quinze Vingts, Service d ophtalmologie 3, 28 rue de Charenton, 75012 Paris
    J Fr Ophtalmol 30:306-13. 2007
    ....
  65. ncbi [Macular hole surgery with and without infracyanine-green-guided removal of the internal limiting membrane]
    M Ullern
    Service d Ophtalmologie, CHNO des XV XX, Paris, France
    J Fr Ophtalmol 30:53-7. 2007
    ..To investigate the possibility of an adverse effect of infracyanine-guided internal limiting membrane (ILM) removal on functional results of macular hole surgery...
  66. ncbi Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey
    Jean Philippe Nordmann
    Hôpital des Quinzes Vingt, Paris, France
    Clin Ophthalmol 4:731-9. 2010
    ..To identify and characterize treatment compliance profiles of glaucoma patients and evaluate the association with intraocular pressure (IOP)...
  67. ncbi Bilateral infectious ulcers associated with atopic keratoconjunctivitis
    Antoine Labbe
    Service d'Ophtalmologie III, Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, Paris, France
    Cornea 25:248-50. 2006
    ..HRT II-RCM in vivo confocal microscopy imaging is useful in monitoring the progression of ocular surface diseases...
  68. ncbi In vivo confocal microscopy in fungal keratitis
    Emmanuelle Brasnu
    Department of Ophthalmology III, Quinze Vingts National Center of Ophthalmology, Paris, France
    Br J Ophthalmol 91:588-91. 2007
    ....
  69. ncbi EMMPRIN modulates epithelial barrier function through a MMP-mediated occludin cleavage: implications in dry eye disease
    Eric Huet
    CRRET Laboratory, Universite Paris Est, CNRS, Creteil, France
    Am J Pathol 179:1278-86. 2011
    ....
  70. ncbi Archipelago keratitis: a clinical variant of recurrent herpetic keratitis?
    Eric E Gabison
    Department of Ophthalmology, Fondation Ophtalmologique A de Rothschild and Bichat Hospital, APHP, Paris, France
    Ophthalmology 114:2000-5. 2007
    ..To describe archipelago keratitis, a presumed clinical variant of herpetic epithelial keratitis...
  71. ncbi [Flow cytometry in impression cytology during keratoconjunctivitis sicca: effects of topical cyclosporin A on HLA DR expression]
    O Galatoire
    Service d'Ophtalmologie 3, , 28, rue de Charenton, 75012 Paris
    J Fr Ophtalmol 26:337-43. 2003
    ..This study confirms that cyclosporin A may be effective in reducing conjunctival inflammation in moderate-to-severe KCS and is consistent with clinical results in this indication...
  72. ncbi [Utility of the Visante OCT in the follow-up of glaucoma surgery]
    A Labbe
    Service d ophtalmologie III, Centre Hospitalier National d Ophtalmologie des Quinze Vingts, Paris
    J Fr Ophtalmol 30:225-31. 2007
    ..To evaluate the utility of the Visante OCT in the follow-up of filtering surgery...
  73. ncbi [Creating a specific diagnostic and quality-of-life questionnaire for patients with ocular surface disease]
    C Baudouin
    CHNO des XV-XX, Paris, France
    J Fr Ophtalmol 26:119-30. 2003
    ..RESULTS: The resulting operational version of the questionnaire included four sections CONCLUSION: The next study will test the reproducibility of the operational version of the OSD questionnaire obtained after the item reduction phase...
  74. ncbi Relationship between in vitro toxicity of benzalkonium chloride (BAC) and preservative-induced dry eye
    M De Saint Jean
    Dept. of Ophthalmology, , Paris, France
    Adv Exp Med Biol 506:697-702. 2002
  75. ncbi [Use of brimonidine 0.2% in treatment of glaucoma or ocular hypertony after poorly tolerated beta-blocker treatment]
    S Titouamane
    CHNO des XV-XX, 28, rue de Charenton, 75012 Paris, France
    J Fr Ophtalmol 25:568-75. 2002
    ..Improved intraocular pressure could at least in part result from better compliance with the treatment. Brimonidine is an encouraging alternative after an unsatisfactory beta-blocker treatment...
  76. ncbi [Wound healing modulation in glaucoma surgery]
    A Labbe
    Service d ophtalmologie III, Centre Hospitalier National d Ophtalmologie des Quinze Vingts, Paris, France
    J Fr Ophtalmol 30:631-46. 2007
    ..The choice of an antifibrotic agent, mode, dose and duration of application should be made with complete knowledge of the different effects of these treatments and adapted for each patient after an exhaustive preoperative evaluation...
  77. ncbi Comparison of morphological and functional characteristics of primary-cultured human conjunctival epithelium and of Wong-Kilbourne derivative of Chang conjunctival cell line
    M De Saint Jean
    Department of Ophthalmology, Ophthalmology National Hospital of Quinze-Vingts, EA3123, University Paris VI, Paris, France
    Exp Eye Res 78:257-74. 2004
    ....
  78. ncbi [Treatment of glaucoma in patients with dry eye syndrome]
    A Labbe
    Service d ophtalmologie 3, Centre Hospitalier National d Ophtalmologie des Quinze Vingts, Paris, France
    J Fr Ophtalmol 33:285-90. 2010
    ..The management of patients with glaucoma or ocular hypertension also suffering from dry eye syndrome needs to reduce eye drop-induced toxicity as well as a specific treatment for the ocular surface...
  79. ncbi [Ocular surface investigations in dry eye]
    A Labbe
    Service d ophtalmologie 3, Centre Hospitalier National d Ophtalmologie des Quinze Vingts, Paris, France
    J Fr Ophtalmol 30:76-97. 2007
    ..Finally, some extraocular explorations such as accessory gland biopsy or serum antinuclear antibody dosage may be useful for assessing the diagnosis of Sjögren's syndrome...
  80. ncbi Protein kinase C-zeta mediates retinal degeneration in response to TNF
    Hong Liang
    INSERM, U598, Physiopathology of ocular diseases therapeutic innovations, Department of Ophthalmology, Quinze Vingts National Ophthalmology Hospital, AP HP, Paris Ouest School of Medicine, Paris, France
    J Neuroimmunol 183:104-10. 2007
    ..The PKCzeta-specific inhibitor unmasks retinal cells to TNF cytotoxicity showing a link between the proapoptotic effects of TNF and the antiapoptotic PKCzeta signaling pathway...
  81. ncbi [Evaluation of NAAGA efficacy in dry eye syndrome]
    F Brignole-Baudouin
    Centre National d Ophtalmologie des Quinze Vingts et UMR_S INSERM 968, Institut de la Vision, Universite Paris 6, Paris
    J Fr Ophtalmol 32:613-20. 2009
    ..The aim of this study was to assess the efficacy of Naabak((R)) eyedrops in reducing inflammation in dry eye syndrome...
  82. ncbi Mitochondrial activity and glutathione injury in apoptosis induced by unpreserved and preserved beta-blockers on Chang conjunctival cells
    C Debbasch
    Unité de Pharmaco Toxicologie Cellulaire, Centre Hospitalier National d Ophtalmologie CHNO des Quinze Vingts, Paris, France
    Invest Ophthalmol Vis Sci 42:2525-33. 2001
    ....
  83. ncbi [Schnyder's crystalline-like corneal dystrophy: a case report]
    E Brasnu
    Service d ophtalmologie III, Centre Hospitalier National d Ophtalmologie des Quinze Vingts, Paris
    J Fr Ophtalmol 33:264.e1-5. 2010
    ..These techniques can be useful in the diagnosis or the therapeutic process, showing crystalline structures that are not clinically distinguishable or validating the histological localization of the corneal disease...
  84. ncbi Cornea in Marfan disease: Orbscan and in vivo confocal microscopy analysis
    Gilles Sultan
    Department of Ophthalmology, Ambroise Pare Hospital, University of Paris-V, Paris, France
    Invest Ophthalmol Vis Sci 43:1757-64. 2002
    ..CONCLUSIONS: MFS is known to be associated with a flattened cornea. This study demonstrated an association with corneal thinning and described confocal microscopy findings in this syndrome...
  85. ncbi [Prevalence and description of treatment with intraocular pressure-lowering topical medications in continental France]
    C Delcourt
    INSERM, , , , , Bordeaux, France
    J Fr Ophtalmol 29:1098-106. 2006
    ..2 million in France. The number of daily doses appears to influence compliance...
  86. ncbi [Antioxidant effects of mast cell inhibitors in a human conjunctival cell line]
    C Debbasch
    , CHNO des Quinze-Vingts, 28, rue de Charenton, 75012 Paris
    J Fr Ophtalmol 24:121-8. 2001
    ..CONCLUSION: In vitro, no cytotoxicity was found with the two unpreserved mast cell inhibitors tested. An antioxidant effect also was observed with these two molecules; sodium cromoglycate appeared to be the best free radical scavenger...
  87. ncbi [OCT and neovascular glaucoma]
    A Bellotti
    Service d ophtalmologie III, Centre Hospitalier National d Ophtalmologie des Quinze Vingts, Paris, France
    J Fr Ophtalmol 30:586-91. 2007
    ..The purpose of our study was to describe the appearance of the different neovascular glaucoma grades with the OCT in order to refine the clinical analysis of this disease...
  88. ncbi [In vivo confocal microscopy: a new tool for the diagnosis of Acanthamoeba keratitis]
    A Grise-Dulac
    Service III, Centre Hospitalier National d Ophtalmologie des Quinze Vingts, Inserm UMRS 968, Institut de la Vision, Universite Pierre et Marie Curie Paris 6, 75012 Paris, France
    J Fr Ophtalmol 33:383-90. 2010
    ..To study the usefulness of in vivo confocal microscopy imaging for the diagnosis of Acanthamoeba keratitis...
  89. ncbi [Contribution of confocal microscopy and anterior chamber OCT to the study of corneal endothelial pathologies]
    N Fayol
    Service d ophtalmologie III, Centre Hospitalier National d Ophtalmologie des Quinze Vingts, Paris, USA
    J Fr Ophtalmol 30:348-56. 2007
    ..To describe the appearance of various endothelial diseases with in vivo confocal microscopy and anterior chamber optical coherence tomography (AC OCT)...
  90. ncbi Comparative study on the cytotoxic effects of benzalkonium chloride on the Wong-Kilbourne derivative of Chang conjunctival and IOBA-NHC cell lines
    E Brasnu
    Department of Ophthalmology III, Quinze Vingts National Ophthalmology Hospital, Paris, France
    Mol Vis 14:394-402. 2008
    ..Therefore, we compared in these two cell types the toxic effects of the preservative, benzalkonium chloride (BAC); its toxicity has been often reported on conjunctival in vivo and in vitro models...
  91. ncbi [Clinical evaluation of the ocular safety of Amukine 0.06% solution for local application versus povidone iodine (Bétadine) 5% solution for ocular irrigation) in preoperative antisepsis]
    F Auclin
    Service d'Ophtalmologie 3, ru Charenton, 75012 Paris, France
    J Fr Ophtalmol 25:120-5. 2002
    ..06% solution was not different from a 5% povidone iodine solution. Therefore, Amukine 0.06% is a new interesting approach to surgical antisepsis in ophthalmology and an alternative in case of iodine allergy...
  92. ncbi [Imaging the ocular surface with confocal microscopy: histology without samples]
    C Baudouin
    Service III, Centre National d Ophtalmologie des Quinze Vingts, Paris
    J Fr Ophtalmol 31:308-16. 2008
    ..The technique is painless and minimally invasive. Confocal microscopy should therefore become a very helpful means to explore ocular surface diseases in the near future...
  93. ncbi [Architectural analysis of clear corneal incisions using Visante OCT in acute postoperative endophthalmitis]
    R Belazzougui
    Service d ophtalmologie III, Centre Hospitalier National d Ophtalmologie des Quinze Vingts, Paris, France
    J Fr Ophtalmol 33:10-5. 2010
    ..To analyze the architecture of clear corneal incisions after acute endophthalmitis following cataract surgery using anterior segment OCT (AS-OCT)...
  94. ncbi [Advantages of confocal microscopy in the analysis of epiretinal membranes and internal limiting membranes after macular surgery]
    F Dubreuil
    Service d'Opthalmologie III, Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, et Inserm U 598, 75012 Paris, France
    J Fr Ophtalmol 28:19-29. 2005
    ..Glial cells were found both in ERM and ILM specimens. Our findings suggest that Müller's cells may contribute to the pathogenesis of ERM and macular hole development...
  95. ncbi [Advantages of the in vivo HRT2 corneal confocal microscope for investigation of the ocular surface epithelia]
    C Leduc
    Service d'Ophtalmologie III, Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, 28, rue de Charenton, 75012 Paris, France
    J Fr Ophtalmol 27:978-86. 2004
    ..But conjunctiva, peripheral cornea and limbus are better examined at the surface and at medium depth with the HRT2. Diagnosis and therapy of superficial corneoconjunctival and limbal diseases are therefore made easier in vivo...