Research Topics
Species | Etienne RouleauSummaryCountry: France Publications
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Detail Information
Publications
High-resolution oligonucleotide array-CGH applied to the detection and characterization of large rearrangements in the hereditary breast cancer gene BRCA1E Rouleau
Laboratoire d oncogénétique, Centre Rene Huguenin, St Cloud, France
Clin Genet 72:199-207. 2007..A refined choice of oligonucleotides should improve the precision of the breakpoint determination. Finally, the high resolution of oligonucleotide array-CGH should help to detect new large rearrangements missed by other current methods...
Quantitative PCR high-resolution melting (qPCR-HRM) curve analysis, a new approach to simultaneously screen point mutations and large rearrangements: application to MLH1 germline mutations in Lynch syndromeEtienne Rouleau
Centre Rene Huguenin, Laboratoire d oncogénétique, Institut Nationale de la Santé et de la Recherche Médicale INSERM U735, Saint Cloud, France
Hum Mutat 30:867-75. 2009..In replicate, its reagent cost, sensitivity, and specificity are comparable to those of dHPLC+MLPA techniques. However, qPCR HRM outperformed the other techniques in terms of its rapidity and amount of data provided...
Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidyIvan Bieche
INSERM U735, Institut Curie Hôpital René Huguenin, St Cloud, France
Mol Cancer 10:23. 2011..Alterations of the mitotic spindle checkpoint are likely to contribute to these phenotypes, but little is known about somatic alterations of mitotic spindle checkpoint genes in breast cancer...
