Research Topics
Species | Thierry LequerreSummaryAffiliation: Rouen University Hospital Country: France Publications
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Detail Information
Publications
Early and long-standing rheumatoid arthritis: distinct molecular signatures identified by gene-expression profiling in synoviaThierry Lequerre
Department of Rheumatology, Rouen University Hospital and Inserm 905 and Institut Fédératif de Recherche Multidisciplinaire sur les Peptides 23, Institute for Biomedical Research, University of Rouen, 76031 Rouen Cedex, France
Arthritis Res Ther 11:R99. 2009..Because previous microarray studies have only focused on long-standing (LS) RA compared to osteoarthritis, we aimed to compare the molecular profiles of early and LS RA versus control synovia...
Gene profiling predicts rheumatoid arthritis responsiveness to IL-1Ra (anakinra)Carine Bansard
Department of Rheumatology, University of Rouen, 76031 Rouen Cedex, France
Rheumatology (Oxford) 50:283-92. 2011..The objective of this study was to predict responsiveness to the anakinra-MTX combination by peripheral blood mononuclear cell gene profiling in order to optimize treatment choice...
A 3 mg/kg starting dose of infliximab in active spondyloarthritis resistant to conventional treatments is efficient, safe and lowers costsGinette Tenga
Department of Pharmacy, Rouen University Hospital, 76031 Rouen Cedex, France
Joint Bone Spine 78:50-5. 2011..We assessed the efficacy, tolerance and cost of a 3 mg/kg starting dose of infliximab for ankylosing spondylitis (AS) and psoriatic arthritis (PsA)...
Smoking and inflammatory diseasesOlivier Vittecoq
Department of Rheumatology, Rouen University Hospital and Inserm U905, Rouen, France
Best Pract Res Clin Rheumatol 22:923-35. 2008..In both diseases, smoking might interfere with drug efficacy...
Combining anti-cyclic citrullinated peptide with the American College of Rheumatology 1987 criteria failed to improve early rheumatoid arthritis diagnosis in the community-based very early arthritis cohortXavier Le Loet
Rheumatology Department, Rouen University Hospital and Inserm Unit 905, University of Rouen, France
Rheumatology (Oxford) 50:1901-7. 2011..To test the performances of combining anti-CCP second generation (CCP2) with ACR 1987 classification criteria and to diagnose early RA in a community-based very early arthritis (VErA) patient cohort...
Number and phenotype of rheumatoid arthritis patients' CD4+CD25hi regulatory T cells are not affected by adalimumab or etanerceptCéline Blache
INSERM, U905, Institut Fédératif de Recherche Multidisciplinaire surles Peptides 23, Institute for Biomedical Research, University of Rouen, Faculte de Medecine Pharmacie, Rouen, France
Rheumatology (Oxford) 50:1814-22. 2011..To analyse the therapeutic effects of etanercept (ETA) or adalimumab (ADA) on the numbers and phenotypes of CD4+CD25hi Tregs in RA patients...
Management of infusion reactions to infliximab in patients with rheumatoid arthritis or spondyloarthritis: experience from an immunotherapy unit of rheumatologyThierry Lequerre
Department of Rheumatology, Rouen University Hospital, Rouen, France
J Rheumatol 33:1307-14. 2006..To suggest recommendations for management of acute infusion reactions induced by infliximab in patients with rheumatoid arthritis (RA) and spondyloarthritis (SpA)...
