V Rigalleau

..We investigated whether loss of bone is detectable during follow-up of diabetic patients with chronic kidney disease (CKD)...

..We sought to determine whether referring asymptomatic diabetic patients for screening of silent ischemia decreases the risk of cardiovascular events compared with usual care...

..0 mg)/g body weight versus isocaloric (glucose 18.2 mg/g) or isoglucidic (glucose 14.0 mg/g) control force-feeding on in vivo changes in hepatic glycogen and ATP contents evaluated ex vivo by NMR in the isolated and perfused liver...

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..This review focuses on the occurrence, mechanisms and consequences of this insulin resistance. Hypoglycaemia is also possible in a minority of uraemic patients; its causes are discussed at the end of the review...

..The more recent Modification of Diet in Renal Disease (MDRD) study equation seems more accurate, but it has not been validated in diabetic patients. This study compares the two methods...

..To identify factors associated with insulin requirement in Type 2 diabetic patients, and to examine the significance of a normal plasma triglyceride level...

..Although it is less easy to calculate, the MDRD is not affected by weight, and its use would avoid delay in referral to nephrologists...

..005) tests. A moderate hyperglycemia inhibits endogenous glucose production and contributes to glucose tolerance by enhancing nonoxidative glucose disposal. Hyperglycemia and oral glucose ingestion both stimulate glucose cycling...

..The less affected MCQ evidences a slower e-GFR decline with AER control...

..Estimation of glomerular filtration rate (GFR) is recommended to diagnose and stratify chronic kidney disease (CKD). Can cystatin-C (cysC) assay improve the results in diabetic patients?..

..3 +/- 0.9 years) and in 8 young (23.6 +/- 0.5) subjects with similar normal body weight...

..We studied the biases in these methods in an attempt to improve the standard CG (MCG) and devise a strategy for stratification...

..73 m2) may be normoalbuminuric. Do the characteristics and outcome differ for subjects with and without albuminuria?..

..The patients who require dialysis often deteriorate their nutritional status, the protein intake must be increased at this stage...

..Hyperglycemia increases glomerular filtration rate (GFR), but the influence of HbA(1c) (A1C) on GFR and GFR's prediction by recommended equations remains to be determined...

..Symptomatic atrial fibrillation should be considered as a potential cause of hyperglycemia...

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..Lean body mass (LBM) is reduced in uremia, but this has not been reported in diabetic nephropathy...

..Therefore, during KSVLPD, strict monitoring of dietetic management is necessary to maintain energy requirements at high levels appropriate to the new EE...

..In type 2 diabetes (T2D), insulin-induced weight gain may stem from a reduction in resting energy expenditure (REE). We sought to determine the early effects of insulin introduction on REE in 20 poorly controlled T2D patients...

..Determination of cystatin C is also promising, but needs standardisation...

..This study aimed to determine how insufficiently suppressed endogenous glucose production vs. reduced peripheral glucose uptake contribute to postprandial hyperglycaemia in type 2 diabetes (T2D)...

..A poor nutritional status reduces the life expectancy of diabetes patients undergoing hemodialysis...

..In the present study, we measured fibrinolytic parameters, including PAI-1 antigen and activity in a group of type 2 diabetic patients in secondary oral anti-diabetic failure treated with insulin alone or with insulin plus metformin...

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..The aim of this study was to evaluate Sudoscan™, a new, quick, non-invasive and quantitative method of measuring sudomotor dysfunction as a co-indicator of the severity of diabetic polyneuropathy (DPN)...

..Moreover, if nowadays we can imagine a tritherapy proposition, progress in chemistry research will conduct to a quadri- and penta-therapy with expected difficulties in therapeutic compliance of the patient...

..To compare a non-programmable and a programmable insulin external pump using regular insulin on glycemic stability, the risk of severe hypoglycemia and metabolic control in type 1 diabetic patients...

..Every diabetic patient with a urinary tract infection who seems to be severely ill should have an abdominal X-ray as a minimal screening tool to detect emphysematous complications...

..To determine the sensitivity of air displacement plethysmography (APD) for evaluation of changes in body composition in normal subjects...

..A diabetic education program requires standardised training of health professionals and the provision of unequivocal information to the mass media and the general public...

..Renal hypertrophy occurs early in diabetic nephropathy, its later value is unknown. Do large kidneys still predict poor outcome in patients with diabetes and Chronic Kidney Disease (CKD)?..

..However, only few studies have examined the course of nutritional status and body composition in the long term (2 years)...

..The respective contribution of these abnormalities remains to be determined...

..We questioned whether the change in proteinuria in response to a supplemented very low protein diet (SVLPD), which is known to reduce proteinuria, could function as a marker of the potential renoprotective effect of an SVLPD...

..Thiazolidinedione have recently shown their interest, but in CRF the balance between risk and benefit remains to be evaluated...

..The aim of this prospective study was to assess the feasibility of LSM when using a new XL probe on patients with a body mass index (BMI) > or =30 kg/m(2)...

..6 g; after, 65.7 +/- 3.6; NS) and diet-induced thermogenesis did not change after normoglycemia. Short-term insulin-induced normoglycemia improves the postprandial oxidation of carbohydrates, but not their storage...

..To compare normal and pathologic values of three different tests for screening patients at risk of foot complications: mono-filament, tuning fork and vibration threshold perception (VTP)...

..We investigated whether air displacement plethysmography (ADP) could detect small changes in body composition of obese subjects with alterations in hydration...

..As levodopa decreases glucose oxidation, the reduction in daily dose of levodopa in STN-DBS-treated patients helps prevent the effect of weight gain on glycaemia...

..Physical inactivity is often suspected in hospitalized patients with type 2 diabetes but has yet to be quantified...

..When insulin, sulfonylurea or glinids are indicated, the dietary intake of carbohydrates has to be regular to avoid hypoglycemia...

..CONCLUSIONS: Familial insulin resistance segregates with diabetic complications: lipid disorders and obesity segregate with diabetic nephropathy, whereas arterial hypertension and obesity segregate with diabetic retinopathy...

..In all cases, the goal remains the control of glycosylated haemoglobin without iatrogenic effects...

..All prescriptions must take into account the existence and extent of kidney disease. Patient adhesion and collaboration between health professionals are required if these measures are to be effective in the long term...

..The kind of this fat-free mass loss (muscular loss, or correction of hyperhydratation) remains a matter of discussion...

..Further studies are needed to evaluate the impact of the cure of occult CS on obesity and diabetes mellitus in these patients. Such studies might provide a rationale for systematic screening of occult CS in this population...

..To evaluate oxidative and antioxidative status in pregnant diabetic women between 26 and 32 weeks of gestation...

..So prevention of type 2 diabetes may be effective. A delay in the appearance of the disease may be quite useful in decreasing the importance of complications by decreasing time exposure to high blood glucose level...