Eric Nguyen-Khac

Summary

Affiliation: place Victor-Pauchet
Country: France

Publications

  1. ncbi Review article: the utility of reagent strips in the diagnosis of infected ascites in cirrhotic patients
    E Nguyen-Khac
    Hepato Gastroenterology, Amiens University Hospital, CHU Nord, Place Victor Pauchet, France
    Aliment Pharmacol Ther 28:282-8. 2008
  2. ncbi Are ascitic electrolytes usable in cirrhotic patients? Correlation of sodium, potassium, chloride, urea, and creatinine concentrations in ascitic fluid and blood
    Eric Nguyen-Khac
    Service d Hépato Gastroentérologie CHU Amiens, France
    Eur J Intern Med 19:613-8. 2008
  3. ncbi Lack of association between tumour necrosis factor receptor types 1 and 2 gene polymorphism and severe acute alcoholic hepatitis
    Eric Nguyen-Khac
    Service d Hepato Gastroenterologie, centre hospitalier universitaire d Amiens, Amiens, France
    Eur J Gastroenterol Hepatol 22:794-800. 2010
  4. ncbi Somatostatin receptor scintigraphy screening in advanced hepatocarcinoma: A multi-center French study
    Eric Nguyen-Khac
    Service d Hépato Gastroentérologie CHU Amiens, Amiens, France
    Cancer Biol Ther 8:2033-9. 2009
  5. ncbi Noninvasive diagnosis of large esophageal varices by Fibroscan: strong influence of the cirrhosis etiology
    Eric Nguyen-Khac
    Department of Hepato Gastroenterology, Amiens University Hospital, France
    Alcohol Clin Exp Res 34:1146-53. 2010
  6. ncbi The -308 TNFalpha gene polymorphism in severe acute alcoholic hepatitis: identification of a new susceptibility marker
    Eric Nguyen-Khac
    Hepatogastroenterology Service, Amiens University Medical Center, Amiens Cedex, France
    Alcohol Clin Exp Res 32:822-8. 2008
  7. ncbi Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis
    Eric Nguyen-Khac
    Service d Hepato Gastroenterologie, Amiens University Hospital, and Equipe Région INSERM 24, University of Picardy, Amiens, France
    N Engl J Med 365:1781-9. 2011
  8. ncbi [Results and place of Fibroscan in the non-invasive diagnosis of hepatic fibrosis]
    E Nguyen-Khac
    Service d Hepatogastroenterologie, CHU d Amiens, Place Victor Pauchet, 80054 Amiens cedex 01, France
    Rev Med Interne 28:94-102. 2007
  9. ncbi Noninvasive diagnosis of liver fibrosis by ultrasonic transient elastography (Fibroscan)
    Eric Nguyen-Khac
    Hepatogastroenterology Service, Amiens University Hospital, Amiens, France
    Eur J Gastroenterol Hepatol 18:1321-5. 2006
  10. ncbi [Portable hemoglobinometer for bedside monitoring of capillary blood hemoglobin in patients with acute gastrointestinal hemorrhage]
    Eric Nguyen-Khac
    Service d Hepato Gastroenterologie, Centre Hospitalier de Cambrai, France
    Presse Med 35:1131-7. 2006

Detail Information

Publications26

  1. ncbi Review article: the utility of reagent strips in the diagnosis of infected ascites in cirrhotic patients
    E Nguyen-Khac
    Hepato Gastroenterology, Amiens University Hospital, CHU Nord, Place Victor Pauchet, France
    Aliment Pharmacol Ther 28:282-8. 2008
    ..Spontaneous bacterial peritonitis (SBP) can be diagnosed via leucocyte esterase reagent strips, although diagnostic performances vary...
  2. ncbi Are ascitic electrolytes usable in cirrhotic patients? Correlation of sodium, potassium, chloride, urea, and creatinine concentrations in ascitic fluid and blood
    Eric Nguyen-Khac
    Service d Hépato Gastroentérologie CHU Amiens, France
    Eur J Intern Med 19:613-8. 2008
    ..A direct measure of ascites could simplify the medical procedure. We aimed to assess the correlation of sodium (Na), potassium (K), chloride (Cl), urea (U), and creatinine (Creat) in ascitic fluid and venous blood...
  3. ncbi Lack of association between tumour necrosis factor receptor types 1 and 2 gene polymorphism and severe acute alcoholic hepatitis
    Eric Nguyen-Khac
    Service d Hepato Gastroenterologie, centre hospitalier universitaire d Amiens, Amiens, France
    Eur J Gastroenterol Hepatol 22:794-800. 2010
    ..We studied the role of TNFR1 and TNFR2 gene polymorphism in AAH patients...
  4. ncbi Somatostatin receptor scintigraphy screening in advanced hepatocarcinoma: A multi-center French study
    Eric Nguyen-Khac
    Service d Hépato Gastroentérologie CHU Amiens, Amiens, France
    Cancer Biol Ther 8:2033-9. 2009
    ..Somatostatin receptor scintigraphy (SRS) has been reported for receptor (SSTR) screening in advanced hepatocarcinoma (aHC) prior to somatostatin analogue treatment...
  5. ncbi Noninvasive diagnosis of large esophageal varices by Fibroscan: strong influence of the cirrhosis etiology
    Eric Nguyen-Khac
    Department of Hepato Gastroenterology, Amiens University Hospital, France
    Alcohol Clin Exp Res 34:1146-53. 2010
    ..Large esophageal varices (LOV) were diagnosed by endoscopy in patients with cirrhosis. Noninvasive method would be valuable...
  6. ncbi The -308 TNFalpha gene polymorphism in severe acute alcoholic hepatitis: identification of a new susceptibility marker
    Eric Nguyen-Khac
    Hepatogastroenterology Service, Amiens University Medical Center, Amiens Cedex, France
    Alcohol Clin Exp Res 32:822-8. 2008
    ..This study investigated whether genetic polymorphisms in the tumor necrosis factor alpha (TNFalpha) gene's promoter region play a role in severe acute alcoholic hepatitis (AAH)...
  7. ncbi Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis
    Eric Nguyen-Khac
    Service d Hepato Gastroenterologie, Amiens University Hospital, and Equipe Région INSERM 24, University of Picardy, Amiens, France
    N Engl J Med 365:1781-9. 2011
    ..Mortality among patients with severe acute alcoholic hepatitis is high, even among those treated with glucocorticoids. We investigated whether combination therapy with glucocorticoids plus N-acetylcysteine would improve survival...
  8. ncbi [Results and place of Fibroscan in the non-invasive diagnosis of hepatic fibrosis]
    E Nguyen-Khac
    Service d Hepatogastroenterologie, CHU d Amiens, Place Victor Pauchet, 80054 Amiens cedex 01, France
    Rev Med Interne 28:94-102. 2007
    ..Diagnosis of liver fibrosis by transient elastography (Fibroscan) is a new and non-invasive method. We report its results, and compare them with the non-invasive biological tests...
  9. ncbi Noninvasive diagnosis of liver fibrosis by ultrasonic transient elastography (Fibroscan)
    Eric Nguyen-Khac
    Hepatogastroenterology Service, Amiens University Hospital, Amiens, France
    Eur J Gastroenterol Hepatol 18:1321-5. 2006
    ..Various diagnostic strategies and performing cost/benefit analyses are now necessary, to assess fully the value of hepatic elastography relative to biological tests for hepatic fibrosis...
  10. ncbi [Portable hemoglobinometer for bedside monitoring of capillary blood hemoglobin in patients with acute gastrointestinal hemorrhage]
    Eric Nguyen-Khac
    Service d Hepato Gastroenterologie, Centre Hospitalier de Cambrai, France
    Presse Med 35:1131-7. 2006
    ..Take blood sample and analysis at laboratory with automatum is the gold standard. A fast determination of hemoglobin at the bedside is possible with a portable haemoglobinometer Hemocue...
  11. ncbi [Acute hepatitis C in 2005]
    Eric Nguyen-Khac
    Service d Hepato Gastroenterologie, CHU d Amiens, Place Victor Pauchet, 80054 Amiens Cedex 1
    Gastroenterol Clin Biol 29:1149-56. 2005
    ..Shorter treatment is possible but high daily doses of interferon are necessary, reducing tolerance. Finally bi therapy with a interferon and ribavirin is not beneficial..
  12. ncbi [Overlap syndrome between primary biliary cirrhosis and autoimmune hepatitis]
    Eric Nguyen-Khac
    , CHG Cambrai
    Gastroenterol Clin Biol 28:1107-16. 2004
  13. ncbi Diagnosis of spontaneous bacterial peritonitis in cirrhotic patients by use of two reagent strips
    Thierry Thevenot
    Service d Hepatogastroenterologie, Hôpital de Cambrai, France
    Eur J Gastroenterol Hepatol 16:579-83. 2004
    ..The improved survival might be explained by a more rapid diagnosis and treatment. The aim of our study was to assess the utility of two reagent strips, the Multistix test and the Combur(2) test LN, for the rapid diagnosis of SBP...
  14. ncbi Ribavirin monitoring in chronic hepatitis C therapy: anaemia versus efficacy
    Etienne Brochot
    Virology Department, Amiens University Medical Center, France
    Antivir Ther 15:687-95. 2010
    ..Lastly, we propose that it would be of particular value to monitor ribavirin concentrations in HCV genotype-1-infected patients and (regardless of the genotype) coinfected patients, haemodialyzed patients and obese patients...
  15. ncbi The treatment response of chronically hepatitis C virus-infected patients depends on interferon concentration but not on interferon gene expression in peripheral blood mononuclear cells
    Catherine François
    Unité de Virologie Clinique et Fondamentale, EA 4294, Université Picardie Jules Verne, Amiens, France
    Antimicrob Agents Chemother 56:903-8. 2012
    ..Although the peripheral blood mononuclear cell samples are the easiest to obtain, the measurement of interferon-inducible genes seems not be the best strategy to predict treatment outcome...
  16. ncbi [Celiac disease and liver involvement]
    Thierry Thevenot
    , Centre Hospitalier de Cambrai
    Gastroenterol Clin Biol 27:28-42. 2003
  17. ncbi BAD, a proapoptotic member of the BCL2 family, is a potential therapeutic target in hepatocellular carcinoma
    Antoine Galmiche
    Laboratoire de Biochimie, CHU Nord, Amiens Cedex, France
    Mol Cancer Res 8:1116-25. 2010
    ..Collectively, our findings indicate that BAD is a key regulator of apoptosis in HCC and an important determinant of HCC cell response to sorafenib...
  18. ncbi Dynamic measurements of total hepatic blood flow with Phase Contrast MRI
    Thierry Yzet
    Department of Radiology, University Hospital, Place Victor Pauchet, 80054 Amiens Cedex 1, France
    Eur J Radiol 73:119-24. 2010
    ..To measure total hepatic blood flow including portal and proper hepatic artery flows as well as the temporal evolution of the vessel's section during a cardiac cycle...
  19. ncbi [Compensation of victims of nosocomial or post-transfusion hepatitis C virus infection]
    Cécile Manaouil
    Service de Consultation de Médecine Légale, CHU d Amiens
    Gastroenterol Clin Biol 31:185-94. 2007
    ....
  20. ncbi [Embolization of recurrent bleeding jejunal varices]
    B Robert
    Service d Imagerie Medicale, CHU d Amiens, Place Victor Pauchet, 80054 Amiens cedex 01, France
    Gastroenterol Clin Biol 34:100-3. 2010
    ..Successful embolisation with coils, of ectopic varices, was performed using original transjugular and trans-TIPS route, without complication, and no recurrence during a follow-up of 24 months...
  21. ncbi [HBsAg screening during pregnancy in the French province Picardy]
    A Braillon
    Réseau hépato Picardie, CHU Nord, Amiens, France
    Gynecol Obstet Fertil 38:13-7. 2010
    ..Screening for maternal hepatitis B surface antigen (HBsAg) is mandatory in France since 1992, however, no evaluation is available. We studied the traceability of HBsAg screening and its prevalence in pregnant women in Picardy for year 2006...
  22. ncbi Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests
    E Nguyen-Khac
    Department of Hepato Gastroenterology, Amiens University Hospital, Place Victor Pauchet, F 80054 Amiens, France
    Aliment Pharmacol Ther 28:1188-98. 2008
    ....
  23. ncbi Low levels of hepatitis C virus (HCV) neutralizing antibodies in patients coinfected with HCV and human immunodeficiency virus
    Sandrine Castelain
    Virologie, CHU Hopital Sud, Amiens, France
    J Infect Dis 198:332-5. 2008
    ..912+/-0.578) (P= .013). Lower HCV nAb titers in coinfected patients could help worsen the outcome of HCV infection. These results favor starting HCV therapy as soon as possible in coinfected patients...
  24. ncbi Antioxidants plus corticosteroids in the treatment of severe acute alcoholic hepatitis: the question is still open
    Eric Nguyen-Khac
    J Hepatol 49:147-8; author reply 148. 2008
  25. ncbi Alpha-1 antitrypsin deficiency and liver disease
    Alain Braillon
    Am J Med 121:e25; author reply e27. 2008
  26. ncbi Model for end-stage liver disease score and systemic inflammatory response are major prognostic factors in patients with cirrhosis and acute functional renal failure
    Dominique Thabut
    AP HP Service d Hépato Gastroentérologie, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Hepatology 46:1872-82. 2007
    ..This suggests that preventing and treating SIRS could decrease mortality in patients with cirrhosis and acute renal failure...