Research Topics
Species | Denise PaulinSummaryCountry: France Publications
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Detail Information
Publications
Synemin expression in developing normal and pathological human retina and lensMarcel Tawk
Biologie Moleculaire de la Differenciation, Universite Paris 7, Case Postale 7136, 2 place Jussieu, 75005, Paris, France
Exp Neurol 183:499-507. 2003..Moreover, stagnant Syn expression in WWS retina and lens reinforces the notion of a significant role of this protein in morphogenesis...
Desminopathies in muscle diseaseDenise Paulin
Universite Denis Diderot Paris 7, Case 7136, Biologie Moleculaire de la Differenciation, 2 place Jussieu, 75251 Paris Cedex, France
J Pathol 204:418-27. 2004....
Desmin: a major intermediate filament protein essential for the structural integrity and function of muscleDenise Paulin
Biologie Moleculaire de la Differenciation, Universite Paris, 75251 Paris, France
Exp Cell Res 301:1-7. 2004..Other desmin-related myopathies, in which the desmin gene is not mutated, could be related to mutations of the genes encoding the proteins that interact with desmin...
Mechanism of binding of serum response factor to serum response elementAlexis Huet
Biologie Moleculaire de la Differenciation, , Paris, France
FEBS J 272:3105-19. 2005..These results indicated that the flexibility of the two partners is crucial for the DNA-protein interaction...
Differences in the activation of the GFAP gene promoter by prion and viral infectionsMatthias Titeux
Biologie Moleculaire de la Differenciation, Universite Paris 7, Case Postale 7136, 2 place Jussieu, 75005 Paris, France
Brain Res Mol Brain Res 109:119-27. 2002..The first 2 kb upstream from the start codon of the GFAP gene seems to provide enough activation domains to produce efficient activation of the reporter gene in prion-infected mice...
Expression of the intermediate filament protein synemin in myofibrillar myopathies and other muscle diseasesMontse Olive
Institut de Neuropatologia, Ciutat Sanitaria i Universitaria de Bellvitge, C Feixa Llarga s n masculine, 08907 Hospitalet de Llobregat, Spain
Acta Neuropathol 106:1-7. 2003....
Intermediate filament-like protein syncoilin in normal and myopathic striated muscleKarl J A McCullagh
MRC Functional Genetics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK
Neuromuscul Disord 17:970-9. 2007..The data show that absence of alpha-dystrobrevin or desmin leads to dynamic changes in syncoilin that may compensate for, or participate in, different muscle myopathies...
New insights into the molecular basis of desmoplakin- and desmin-related cardiomyopathiesKarine Lapouge
Clinic of Dermatology, University Hospital, Geneva, Rue Micheli-du-Crest 14, 1211-Geneva 14, Switzerland
J Cell Sci 119:4974-85. 2006....
Human alpha-synemin interacts directly with vinculin and metavinculinNing Sun
Muscle Biology Group, Department of Biochemistry, Biophysics and Molecular Biology and of Animal Science, Iowa State University, Ames, IA 50011 3260, USA
Biochem J 409:657-67. 2008....
Identification of a repeated domain within mammalian alpha-synemin that interacts directly with talinNing Sun
Muscle Biology Group, Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, IA 50011 3260, USA
Exp Cell Res 314:1839-49. 2008....
Selective microvascular dysfunction in mice lacking the gene encoding for desminLaurent Loufrani
Institut National de la Santé et de la Recherche Médicale INSERM U 541, IFR Circulation Paris Nord, Paris VII University, Paris, France
FASEB J 16:117-9. 2002..This microvascular defect found in the absence of desmin might play a major role in myopathies seen in desmin-related diseases...
Absence of dystrophin in mice reduces NO-dependent vascular function and vascular density: total recovery after a treatment with the aminoglycoside gentamicinLaurent Loufrani
Institut National de la Santé et de la Recherche Médicale Unité 541, Paris, France
Arterioscler Thromb Vasc Biol 24:671-6. 2004..We investigated the effect of gentamicin on vascular contractile and dilatory functions, vascular structure, and density in mdx mice...
Temporal patterns of bone marrow cell differentiation following transplantation in doxorubicin-induced cardiomyopathyOnnik Agbulut
INSERM U572, Hopital Lariboisiere, 41, Bd de la Chapelle, 75475 Cedex 10, Paris, France
Cardiovasc Res 58:451-9. 2003..To extend the potential of cell transplantation, we assessed this treatment in a mouse model of acute nonischemic doxorubicin-induced cardiomyopathy...
Excessive microvascular adaptation to changes in blood flow in mice lacking gene encoding for desminLaurent Loufrani
Institut National de la Santé et de la Recherche Médicale U 541, IFR Circulation Paris Nord, Paris, France
Arterioscler Thromb Vasc Biol 22:1579-84. 2002..We investigated the effect of the absence of desmin in mice (Des-/- mice versus Des+/+ mice) on the adaptation of mesenteric arteries to changes in blood flow...
Comparative study of immune responses induced after immunization with plasmids encoding the HIV-1 Nef protein under the control of the CMV-IE or the muscle-specific desmin promoterNicolas Cazeaux
, EA 3038, Laboratoire d'Immuno-Virologie, 118 route de Narbonne, 31062 Toulouse Cedex, France
Vaccine 20:3322-31. 2002..In conclusion, these data indicate that antigen expression by muscle cells is sufficient to stimulate a Th1 immune response...
Mechanical function of intermediate filaments in arteries of different size examined using desmin deficient miceOskar Karlsson Wede
Department of Physiological Sciences, Lund University, Lund, Sweden
J Physiol 540:941-9. 2002..In the microarteries, where expression of desmin is high, desmin plays a role in supporting both passive and active tension...
Analysis of mural cell recruitment to tumor vesselsAlexandra Abramsson
Department of Medical Biochemistry, , , Sweden
Circulation 105:112-7. 2002..T241 tumor vessels seem highly capable of recruiting exogenously added mural cells. The sparse mural cell coat of tumor vessels may result from a limited pool of mural cells available for recruitment...
Myofiber integrity depends on desmin network targeting to Z-disks and costameres via distinct plectin isoformsPatryk Konieczny
Max F Perutz Laboratories, Department of Molecular Cell Biology, University of Vienna, A 1030 Vienna, Austria
J Cell Biol 181:667-81. 2008..Our findings establish plectin as the major organizer of desmin IFs in myofibers and provide new insights into plectin- and desmin-related muscular dystrophies...
