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Genomes and Genes | R NadifSummaryCountry: France Publications
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Publications
Association of CAT polymorphisms with catalase activity and exposure to environmental oxidative stimuliRachel Nadif
INSERM U472 IFR69, Villejuif, France
Free Radic Res 39:1345-50. 2005..01). Haplotype analyses (combined CAT SNPs) confirm these results. Results show that CAT -262 and LTA NcoI SNPs, and interaction with coal dust exposure, influenced catalase activity...- Effect of TNF and LTA polymorphisms on biological markers of response to oxidative stimuli in coal miners: a model of gene-environment interaction. Tumour necrosis factor and lymphotoxin alphaR Nadif
INSERM U 472 IFR69, Villejuif, France
J Med Genet 40:96-103. 2003..Interaction between genetic background and oxidative environmental stimuli in the pathogenesis of human lung disease has been largely unexplored... - IL18 and IL18R1 polymorphisms, lung CT and fibrosis: A longitudinal study in coal minersR Nadif
INSERM, Recherche en Epidémiologie et Biostatistique U780, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif Cedex, France
Eur Respir J 28:1100-5. 2006..In conclusion, the results of the present study suggest a role for IL18 in reducing the development of this fibrosing lung disease... - Polymorphisms in chemokine and chemokine receptor genes and the development of coal workers' pneumoconiosisRachel Nadif
INSERM, U472, Villejuif, France
Cytokine 33:171-8. 2006..7%, 13.2%, 0.0% for VV, VI and II); the effect was most evident in miners with high dust exposure (31.6%, 21.7%, 0.0%). Our findings indicate that chemokine receptors CCR5 and CX3CR1 may be involved in the development of pneumoconiosis... - Cat sensitization according to cat window of exposure in adult asthmaticsM P Oryszczyn
INSERM, U780, Epidemiology and Biostatistics, Villejuif, France
Clin Exp Allergy 39:1515-21. 2009..In adults, there is limited information on tolerance to cat, which may be reflected by high IgG4 without IgE sensitization. Early exposure to cat may play a critical role... - CD14 and toll-like receptor gene polymorphisms, country living, and asthma in adultsLidwien A M Smit
INSERM U780, Villejuif, France
Am J Respir Crit Care Med 179:363-8. 2009..It has been shown that country living protects against asthma, which may be explained by microbial exposures... - Total serum IgE levels are associated with ambient ozone concentration in asthmatic adultsE Rage
INSERM, U780, Epidemiology and Biostatistics, Villejuif, France
Allergy 64:40-6. 2009..Effects of air pollution exposure on IgE-mediated response in asthmatics are poorly investigated. The aim was to examine the relationship between air pollution concentrations and total IgE levels in adult asthmatics... - Air pollution and asthma severity in adultsE Rage
INSERM U780, 16 Avenue Paul Vaillant Couturier, Villejuif Cedex, France
Occup Environ Med 66:182-8. 2009..The aim was to assess the relation between asthma severity during the past 12 months and home outdoor concentrations of air pollution... - Heterogeneity of asthma according to blood inflammatory patternsR Nadif
Institut National de la Sante et de la Recherche Medicale, Villejuif, France
Thorax 64:374-80. 2009..There is increasing interest regarding asthma heterogeneity in relation to inflammatory patterns... - Relationship between blood antioxidants and occupational exposure to polycyclic aromatic hydrocarbons in coke oven workersR Nadif
INSERM U 420, Faculte de Medecine, Vandoeuvre les Nancy, France
Am J Ind Med 34:272-9. 1998..We investigated if blood Cu++/Zn++ superoxide dismutase, glutathione peroxidase, and catalase activities are increased and total plasma antioxidant concentration is decreased in coke oven workers exposed to polycyclic aromatic hydrocarbons... - Do young adults with childhood asthma avoid occupational exposures at first hire?O Dumas
Respiratory and Environmental Epidemiology, CESP U 1018 Inserm, Villejuif Cedex, France
Eur Respir J 37:1043-9. 2011..98, 95% CI 0.44-2.22), with consistent results for all asthma characteristics. Results suggest a healthy worker hire effect in subjects with more severe or more symptomatic asthma in childhood. Education may modulate self-selection... - Cross sectional and longitudinal study on selenium, glutathione peroxidase, smoking, and occupational exposure in coal minersR Nadif
INSERM U 420, Epidémiologie Santé Travail, Faculte de Medecine, BP 184, 54505 Vandouvre lès Nancy Cedex, France
Occup Environ Med 58:239-45. 2001..To better understand the relation of Se concentration with glutathione peroxidase activities (GSH-Px) in these miners... - Interrelationships of quantitative asthma-related phenotypes in the Epidemiological Study on the Genetics and Environment of Asthma, Bronchial Hyperresponsiveness, and AtopyMarie Pierre Oryszczyn
INSERM, U780, Epidemiology and Biostatistics, Villejuif Univ Paris Sud, IFR69, Villejuif, France
J Allergy Clin Immunol 119:57-63. 2007..Delineating asthma subphenotypes is of interest to understand the cause of the disease. Few studies have addressed the interrelationships of quantitative asthma-related traits... - Not only training but also exposure to chlorinated compounds generates a response to oxidative stimuli in swimmersRaphaelle Varraso
INSERM U420, Faculte de Medecine, BP 184, 54505 Vandauvre leś Nancy, France
Toxicol Ind Health 18:269-78. 2002..Other athletes tend to have respiratory problems such as asthma, but the exposure to chlorinated compounds may increase the respiratory disease among swimmers... - Passive and active smoking and exhaled nitric oxide levels according to asthma and atopy in adultsRachel Nadif
INSERM, CESP Centre for research in Epidemiology and Population Health, Respiratory and Environmental Epidemiology Team U1018, Villejuif, France
Ann Allergy Asthma Immunol 104:385-93. 2010..No data are available regarding the utility of fractional exhaled nitric oxide (FeNO) level in guiding therapy in smoking asthmatic patients. Identification of the effect of smoking in a large sample is needed... - Sex-specific effect of IL9 polymorphisms on lung function and polysensitizationH Aschard
INSERM, U946, Fondation Jean Dausset CEPH, Paris 75010, France
Genes Immun 10:559-65. 2009..002, respectively, after Bonferroni's correction). This study underlies the importance of taking into account complex mechanisms, such as heterogeneity according to sex and pleiotropy to unravel the genes involved in asthma phenotypes... - Phenotypic determinants of uncontrolled asthmaValerie Siroux
INSERM, Institut National de la Sante et de la Recherche Medicale, U823, Institut Albert Bonniot, Grenoble, France
J Allergy Clin Immunol 124:681-7.e3. 2009..Although uncontrolled asthma remains frequent, determinants of asthma control are poorly studied... - Replication of association between ADAM33 polymorphisms and psoriasisValerie Siroux
INSERM, U823, Centre de Recherche Albert Bonniot, Epidémiologie des cancers et des affections graves, La Tronche, France
PLoS ONE 3:e2448. 2008..The identification of a pleiotropic effect of ADAM33 on asthma and psoriasis may contribute to the understanding of these common immune-mediated diseases... - Re: "Associations between breast cancer risk and the catalase genotype, fruit and vegetable consumption, and supplement use"Rachel Nadif
Am J Epidemiol 163:874-5. 2006 - Chronic exposure to anesthetic gases affects balance control in operating room personnelAlexandre Vouriot
National Institute for Health and Medical Research (INSERM, U420, Faculty of Medicine, , France
Neurotoxicology 26:193-8. 2005..By impairing information and its central integration, exposure to anesthetics gases leads to inappropriate organization of sensorimotor stabilization strategies...