Research Topics
| Louis MonnierSummaryCountry: France Publications
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Publications
Contributions of fasting and postprandial glucose to hemoglobin A1cLouis Monnier
Department of Metabolism, Lapeyronie Hospital, Montpellier, France
Endocr Pract 12:42-6. 2006..Postmeal thresholds for predicting good or satisfactory control of diabetes are dependent on the timing of the meals...
Morning hyperglycemic excursions: a constant failure in the metabolic control of non-insulin-using patients with type 2 diabetesLouis Monnier
Department of Metabolic Diseases, Lapeyronie Hospital, Montpellier, France
Diabetes Care 25:737-41. 2002..To determine whether, over daytime, one or several hyperglycemic excursions exist that can be general failures in the glycemic control of patients with type 2 diabetes...
Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetesLouis Monnier
Department of Metabolic Diseases, Lapeyronie Hospital, University of Montpellier, Montpellier, France
JAMA 295:1681-7. 2006..Glycemic disorders, one of the main risk factors for cardiovascular disease, are associated with activation of oxidative stress...
Postprandial hyperglycaemia and cardiovascular complications of diabetes: an updateAntonio Ceriello
Clinical Science Research Institute, Clinical Science Building, Warwick Medical School, University of Warwick, Coventry, UK
Nutr Metab Cardiovasc Dis 16:453-6. 2006..Therefore, in addition to HbA1c and FPG, physicians should consider monitoring and targeting PPG in patients with type 2 diabetes...
Continuous glucose monitoring in patients with type 2 diabetes: Why? When? Whom?L Monnier
Department of Metabolic Diseases, Lapeyronie Hospital, 34295 Montpellier cedex 05, France
Diabetes Metab 33:247-52. 2007....
Studying the Hurdles of Insulin Prescription (SHIP): development, scoring and initial validation of a new self-administered questionnaireLuc Martinez
French Society of General Medicine, Issy les Moulineaux, France
Health Qual Life Outcomes 5:53. 2007..A better understanding of patients' perception of insulin would eventually help physicians to adopt the most appropriate dialogue when having to motivate patients to initiate or to intensify insulin injection...
Insulin secretion and sensitivity as determinants of HbA1c in type 2 diabetesL Monnier
Department of Metabolic Diseases, Lapeyronie Hospital, University Institute of Clinical Research, Montpellier, France
Eur J Clin Invest 36:231-5. 2006..The present study was designed to compare the respective roles of both determinants on HbA1c, in type 2 diabetic patients, according to whether or not residual beta-cell function was stimulated with insulin secretagogues...
Type 2 diabetes: a well-characterised but suboptimally controlled disease. Can we bridge the divide?L Monnier
Laboratory of Human Nutrition, University Institute of Clinical Research, 34093 Montpellier Cedex 5, France
Diabetes Metab 34:207-16. 2008....
Glycemic variability: should we and can we prevent it?Louis Monnier
Department of Metabolic Diseases, Lapeyronie Hospital, 34295 Montpellier Cedex 5, France
Diabetes Care 31:S150-4. 2008..e., the glucose instability). Particular attention should be paid to such emerging therapeutic agents as the glucagon-like peptide 1 agonists and the dipeptidyl peptidase (DPP)-IV inhibitors that act through the incretin pathway...
The loss of postprandial glycemic control precedes stepwise deterioration of fasting with worsening diabetesLouis Monnier
Department of Metabolic Diseases, Lapeyronie Hospital, 34295 Montpellier Cedex 5, France
Diabetes Care 30:263-9. 2007..The aim of the study was to determine whether the loss of fasting and postprandial glycemic control occurs in parallel or sequentially in the evolution of type 2 diabetes...
Contribution of postprandial glucose to chronic hyperglycaemia: from the "glucose triad" to the trilogy of "sevens"L Monnier
Department of Metabolic Diseases, Hopital Lapeyronie, 34295 Montpellier cedex 05
Diabetes Metab 32:2S11-6. 2006....
[Type 1 diabetes of the child and the adult. Type 2 diabetes of the adult. Complications of diabetes]Louis Monnier
, , 34295 Montpellier 5
Rev Prat 57:653-64. 2007
Addition of rapid-acting insulin to basal insulin therapy in type 2 diabetes: indications and modalitiesL Monnier
Hôpital Lapeyronie Service des maladies métaboliques, 34295 Montpellier Cedex 5, France
Diabetes Metab 32:7-13. 2006..This stepwise strategy may eventually lead to a standard basal-bolus regimen with 3 pre-meal injections of rapid-acting insulin analogues, a potentially small trade-off for achieving fairly-well controlled diabetes...
[Pioglitazone insulin sensitivity and type 2 diabetes mellitus: recent data]L Monnier
Service des Maladies Métaboliques, Hopital Lapeyronie, CHU de Montpellier
Ann Endocrinol (Paris) 65:136-48. 2004....
An overview of the rationale for pharmacological strategies in type 2 diabetes: from the evidence to new perspectivesL Monnier
Department of Metabolism, Lapeyronie Hospital, 34295 Montpellier Cedex 5, France
Diabetes Metab 31:101-9. 2005..3%...
Integrating glycaemic variability in the glycaemic disorders of type 2 diabetes: a move towards a unified glucose tetrad conceptLouis Monnier
Department of Metabolic Diseases, Lapeyronie Hospital, Montpellier, France
Diabetes Metab Res Rev 25:393-402. 2009..This brings together, in a simple, unified concept, the conventional markers (HbA(1c) and fasting glucose) and the more recently recognized markers of glycaemic control (PPG excursions and acute glycaemic variability)...
Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycemia of type 2 diabetic patients: variations with increasing levels of HbA(1c)Louis Monnier
Department of Metabolism, Lapeyronie Hospital, Montpellier, France
Diabetes Care 26:881-5. 2003..To test the effect of overall glycemic control itself, we analyzed the diurnal glycemic profiles of type 2 diabetic patients investigated at different levels of HbA(1c)...
Global assessment for quality and safety of control in type 2 diabetic patientsL Monnier
Department of Metabolism, Lapeyronie Hospital, Montpellier Cedex, France
Eur J Clin Invest 34:37-42. 2004..This study was conducted to discern whether the monitoring of one particular plasma glucose (PG) value of the diurnal profile can be used in such situations...
Management of French patients with type 2 diabetes mellitus in medical general practice: report of the Mediab observatoryL Monnier
Department of Metabolic Diseases, Lapeyronie Hospital, Montpellier, France
Diabetes Metab 30:35-42. 2004..The Mediab study was conducted to estimate the medical care in French patients with type 2 diabetes mellitus managed by general practitioners on an ambulatory basis, but consIdered as requiring new treatment implementation...
Insulin therapy has a complex relationship with measure of oxidative stress in type 2 diabetes: a case for further studyLouis Monnier
Laboratory of Human Nutrition and Atherogenesis, University Institute of Clinical Research, Montpellier Cedex 5, France
Diabetes Metab Res Rev 27:348-53. 2011....
Targeting prandial hyperglycemia: how important is it and how best to do this?Louis Monnier
Laboratory of Human Nutrition, University Institute of Clinical Research, 641 Avenue du Doyen Giraud, 34093 Montpellier Cedex 5, France
Curr Diab Rep 8:368-74. 2008....
The contribution of glucose variability to asymptomatic hypoglycemia in persons with type 2 diabetesLouis Monnier
Laboratory of Human Nutrition and Atherosclerosis, Institute of Clinical Research of Montpellier I, Montpellier, France
Diabetes Technol Ther 13:813-8. 2011..The present study was designed to define the relative contributions of glucose variability and ambient glycemia to the incidence of asymptomatic hypoglycemia in type 2 diabetes...
Fasting glucose and postprandial glycemia: which is the best target for improving outcomes? The Apollo and 4-T TrialsLouis Monnier
University of Montpellier I, Institute of Clinical Research, 641 Avenue du Doyen Giraud, 34093 Montpellier Cedex 5, France
Expert Opin Pharmacother 9:2857-65. 2008..Two studies, the Apollo and 4-T Trials, were conducted in order to determine which insulin regimen (basal or prandial) is the most efficient for the treatment of insulin-requiring type 2 diabetic patients...
Postprandial and basal glucose in type 2 diabetes: assessment and respective impactsLouis Monnier
Laboratory of Human Nutrition and Atherosclerosis, Institute of Clinical Research, University of Montpellier I, Montpellier, France
Diabetes Technol Ther 13:S25-32. 2011..This key feature clearly depicts the absolute contribution of PPG in contrast to its relative contribution and better explains why PPG contributes to the excess of glycation with the basal hyperglycemia...
Guideline for management of postmeal glucoseAntonio Ceriello
Warwick Medical School, Clinical Science Research Institute, Clinical Science Building, University Hospital Walsgrave Campus, Clifford Bridge Road, Coventry CV2 2DX, UK
Nutr Metab Cardiovasc Dis 18:S17-33. 2008..This guideline reviews the evidence on the harmful effects of elevated postmeal glucose and makes recommendations on its treatment, assessment and targets...
Postprandial glucose regulation: new data and new implicationsLawrence A Leiter
St Michael s Hospital, University of Toronto, Toronto, Canada
Clin Ther 27:S42-56. 2005..However, physicians continue to rely on fasting plasma glucose (FPG) and glycosylated hemoglobin (HbA1c) to guide management...
Postprandial glucose regulation and diabetic complicationsAntonio Ceriello
Department of Pathology and Medicine Experimental and Clinical, University of Udine, Udine, Italy
Arch Intern Med 164:2090-5. 2004..The present review examines the hypothesis that controlling postprandial glucose level is an important strategy in the prevention of cardiovascular complications associated with diabetes...
The effect of glucose variability on the risk of microvascular complications in type 1 diabetesLouis Monnier
Diabetes Care 30:185-6; author reply 187-8. 2007
Insulin alters nuclear factor-lambdaB and peroxisome proliferator-activated receptor-gamma protein expression induced by glycated bovine serum albumin in vascular smooth-muscle cellsCristina De Oliveira
,
J Lab Clin Med 145:144-50. 2005..These data may help justify current therapeutic approaches involving the use of insulin and PPAR-gamma agonists...
Inflammatory parameters are independent predictors of severe epicardial coronary stenosis in asymptomatic diabetic patients with silent myocardial ischemiaChristophe Piot
Cardiovascular Diseases Department, Montpellier University Hospital, France
Diabetes Care 26:545-6. 2003
Modulation of CD36 protein expression by AGEs and insulin in aortic VSMCs from diabetic and non-diabetic ratsCristina de Oliveira Silva
Laboratoire de Nutrition Humaine et Athérogénèse LNHA, EA 2993, Institut Universitaire de Recherche Clinique, Universite Montpellier I, 641 Avenue du Doyen Giraud, 34093 Montpellier, France
Nutr Metab Cardiovasc Dis 18:23-30. 2008..The context of overexpression of CD36 in aortas was also evaluated...
