Luc Letenneur

..Several studies have been published and the overall conclusion is that heavy drinking is a risk factor for most stroke subtypes. Regular light to moderate drinking seemed to be associated with a decreased risk for ischaemic stroke...

..Dietary patterns that represent a combination of foods may better predict disease risk than single foods or nutrients...

..Depressive symptoms are commonly observed in elderly people, and nutritional factors such as polyunsaturated fatty acids (PUFAs) have been proposed as potential protective determinants of depressive disorders...

..9 and decreased with higher educational level. The present results suggest that being female, older age, being widowed and low income level could be considered as risk factors of inadequate dietary intake...

..0; 95% CI, 0.6-1.6). Our finding suggest that former use of benzodiazepines could be a risk factor for dementia, but more detailed investigation are needed...

..To analyze the prevalence of dementia by severity and to describe the sociodemographic characteristics of people with dementia in the community, as well as the consequences of this disease in terms of disability and institutionalization...

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..Benzodiazepines are frequently used medications in the elderly, in whom they are associated with an increased risk of falling, with sometimes dire consequences...

..Therefore the results support the hypothesis that impaired shifting abilities - rather than semantic memory storage degradation - could explain the early decline in semantic fluency performance occurring in the predementia phase of AD...

..Thus, these results suggest that use of FT-IR spectroscopy could be valuable to distinguish AD patients from normal-aging subjects...

..Plasma n-3 PUFAs have been shown to be inversely related to the risk of dementia and to depression, which is frequently associated with dementia...

..7% did not benefit from the presentation of the model. Analysis showed that persistent failure in the copy condition was the best level of differentiation between normal and AD subjects...

..Subjects with higher education exhibited a better mean score for the 4 tests, but this difference tended to attenuate with age for tests involving a speed component...

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..In this latter case, high-educated patients may still benefit from cognitive reserve after the diagnosis of the dementia...

..Among the variables considered, the Letter Cancellation Test proved to be a major predictor of short-term conversion to dementia...

..These results suggest that tobacco consumption is not associated with a lower risk of dementia and that moderate alcohol intake does not increase the risk of developing dementia...

..Additionally, the two groups significantly improved their time performances all along the test suggesting that both groups including the pre-demented group were able to progressively acquire a target detection skill...

..Our aim was to study the 10-year evolution of disability prevalence in elderly community dwellers and related factors...

..These results suggest the presence of neurologic impairments in elderly persons who were exposed occupationally to pesticides...

..The predictive ability of the model is illustrated by predicting diagnosis of dementia at the 8 year follow-up of the PAQUID study based on the information from the first 5 years...

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..The ability of high educational level subjects to use more efficient strategies may participate to the 'cognitive reserve' capacity...

..These results provided no evidence that microwave radiation, at the levels produced by mobile phones, caused damage to the inner ear or the auditory pathways in our experimental animals...