Research Topics
| Vincent Launay-VacherSummaryCountry: France Publications
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Publications
[How to adjust the dose of drugs in chronic kidney disease?]Vincent Launay-Vacher
Service ICAR, Service de Nephrologie, Groupe Hospitalier La Pitié Salpêtrière, AP HP, 75013 Paris
Rev Prat 62:309-11, 314-5. 2012..However, some information sources exist, reliable, updated, and easily accessible...
Drug management of prostate cancer: prevalence and consequences of renal insufficiencyVincent Launay-Vacher
Department of Nephrology Pr Deray, Hopital Pitie Salpetriere, Paris, France
Clin Genitourin Cancer 7:E83-9. 2009..A national multicenter study from 15 cancer centers in France analyzed IRMA data on patients with prostate cancer...
Evolution of renal function in patients treated with antiangiogenics after nephrectomy for renal cell carcinomaVincent Launay-Vacher
Department of Nephrology, Hopital Pitie Salpetriere, Paris, France
Urol Oncol 29:492-4. 2011..e., glomerular filtration rate (GFR). We report on the evolution of GFR in patients receiving antiangiogenic therapy after unilateral nephrectomy for kidney cancer...
Epidemiology of chronic kidney disease in cancer patients: lessons from the IRMA study groupVincent Launay-Vacher
Service ICAR, Service de Nephrologie, Hopital Pitie Salpetriere, Paris, France
Semin Nephrol 30:548-56. 2010..This reduced survival has been hypothesized to be related to the cardiovascular complications of KD or as a consequence of inappropriate drug dosage adjustment...
Prevention of cisplatin nephrotoxicity: state of the art and recommendations from the European Society of Clinical Pharmacy Special Interest Group on Cancer CareVincent Launay-Vacher
ICAR, Department of Nephrology, Hopital Pitie Salpetriere, 83 Boulevard de l hopital, 75013 Paris, France
Cancer Chemother Pharmacol 61:903-9. 2008....
[Chemotherapy and renal toxicity]Vincent Launay-Vacher
Service de Nephrologie, Hopital de la Pitie Salpetriere, 83, Boulevard de l Hopital, 75013 Paris, France
Bull Cancer 95:F96-103. 2008....
Prevalence of renal insufficiency in breast cancer patients and related pharmacological issuesVincent Launay-Vacher
Department of Nephrology, Hopital Pitie Salpetriere, Paris, France
Breast Cancer Res Treat 124:745-53. 2010..Both issues seem to be slightly but significantly more important in patients with bone metastases as compared to patients with a non-metastatic disease...
Hypertension and proteinuria: a class-effect of antiangiogenic therapiesVincent Launay-Vacher
Department of Nephrology, Pitie Salpetriere Hospital, Paris, France
Anticancer Drugs 20:81-2. 2009..Clinicians should thus be aware of such a 'class effect' to appropriately monitor and treat their patients, regardless of which antiangiogenic drug is used...
Renal insufficiency and anticancer drugs in elderly cancer patients: a subgroup analysis of the IRMA studyVincent Launay-Vacher
Department of Nephrology, Hopital Pitie Salpetriere, Paris, France
Crit Rev Oncol Hematol 70:124-33. 2009..Anticancer drugs used may be nephrotoxic or need dosage adjustment in a high number of cases...
Lung cancer and renal insufficiency: prevalence and anticancer drug issuesVincent Launay-Vacher
Department of Nephrology, Pr Deray, Hopital Pitie Salpetriere, 47 83 boulevard de l Hopital, 75013 Paris, France
Lung 187:69-74. 2009..Lung cancer patients often present with anemia, which was not associated with the presence of RI...
Incidence of renal insufficiency in cancer patients and evaluation of information available on the use of anticancer drugs in renally impaired patientsVincent Launay-Vacher
Department of Nephrology, Pitié Salpetricre Hospital, Paris, France
Med Sci Monit 10:CR209-12. 2004..The high frequency of this disease in the general US population has been assessed in the NHANES III study. However, the frequency of chronic renal insufficiency among cancer patients remains unclear...
Prevalence of Renal Insufficiency in cancer patients and implications for anticancer drug management: the renal insufficiency and anticancer medications (IRMA) studyVincent Launay Vacher
Department of Nephrology, Pitie Salpetriere Hospital, Paris, France
Cancer 110:1376-84. 2007..The results from this study of nearly 5,000 patients demonstrated the high prevalence of renal impairment in a population of patients with solid tumors...
Long-term renal safety of tenofovir disoproxil fumarate in antiretroviral-naive HIV-1-infected patients. Data from a double-blind randomized active-controlled multicentre studyHassane Izzedine
Department of Nephrology, Pitie Salpetriere Hospital, 47 83 boulevard de l Hopital, 75013 Paris, France
Nephrol Dial Transplant 20:743-6. 2005..However, controlled data are sparse on the long-term renal tolerability of TDF at the currently approved daily dose of 300 mg in treatment-naive HIV-infected patients...
Renal safety of adefovir dipivoxil in patients with chronic hepatitis B: two double-blind, randomized, placebo-controlled studiesHassane Izzedine
Department of Nephrology, Pitie Salpetriere Hospital, Paris, France
Kidney Int 66:1153-8. 2004..We report a complete analysis on the renal tolerance of ADV at the currently approved dose of 10 mg daily for the treatment of chronic hepatitis B...
Antiretroviral drugs and the kidney: dosage adjustment and renal toleranceHassane Izzedine
Department of Nephrology, Pitie Salpetriere Hospital, Paris, France
Curr Pharm Des 10:4071-9. 2004..6 to 1%). Therefore, administration of antiretroviral drugs in human immunodeficiency virus (HIV) patients with nephropathy is not uncommon...
[Anticancer drug-induced nephrotoxicity]Corinne Isnard-Bagnis
Service de Nephrologie, Hopital Pitie Salpetriere, 83, Boulevard de l Hopital, 75013 Paris, France
Nephrol Ther 1:101-14. 2005....
Drug-induced diabetes mellitusHassane Izzedine
Department of Nephrology, Pitie Salpetriere Hospital, Paris, France
Expert Opin Drug Saf 4:1097-109. 2005..To review the medications that influence glucose metabolism with a focus on hypertensive, transplant and HIV-infected patient populations...
Clinical review: use of vancomycin in haemodialysis patientsVincent Launay-Vacher
Department of Nephrology, Pitie Salpetriere Hospital, Paris, France
Crit Care 6:313-6. 2002..The aim of the present review is to establish guidelines for handling this drug in such patients. We indicate how and when plasma concentrations of vancomycin should be determined in dialysis patients...
Renal safety of tenofovir in HIV treatment-experienced patientsHassane Izzedine
Department of Nephrology, , Paris, France
AIDS 18:1074-6. 2004..Proximal tubulopathy was diagnosed 6.89 +/- 5.51 months after TDF therapy started. All abnormalities normalized within 4.7 +/- 2.94 weeks after drug discontinuation...
Antiretroviral and immunosuppressive drug-drug interactions: an updateHassane Izzedine
Department of Nephrology, Pitie Salpetriere Hospital, Paris, France
Kidney Int 66:532-41. 2004....
Prevalence of nephrogenic systemic fibrosis in renal insufficiency patients: results of the FINEST studyNicolas Janus
Department of Nephrology, Pitie Salpetriere Hospital, 83 Boulevard de l hopital, 75013 Paris, France
Eur J Radiol 73:357-9. 2010..The FINEST study (FIbrose Néphrogénique SysTémique) was designed to determine the prevalence of NSF after magnetic resonance imaging (MRI) in French RI patients...
FHD: an index to evaluate drug elimination by hemodialysisVincent Launay-Vacher
Department of Nephrology, , Paris, France
Am J Nephrol 25:342-51. 2005..F(HD )could be the index of choice to determine when to administer a drug, before or after the session, in hemodialysis patients...
Antiretroviral drug dosing errors in HIV-infected patients undergoing hemodialysisJérôme Tourret
Nephrology Department, Groupe Hospitalier Pitie Salpetriere, Paris, France
Clin Infect Dis 45:779-84. 2007..We analyzed highly active antiretroviral therapy (HAART) prescribing practices for human immunodeficiency virus (HIV)-infected patients undergoing hemodialysis in France...
[Is dialysis efficient in the prevention of ionic contrast agent-induced nephropathy?]Svetlana Karie
Service de Nephrologie, Groupe hospitalier Pitié Salpêtrière 83, boulevard de I hôpital, 75013 Paris, France
Presse Med 34:803-8. 2005..No data yet justify a conclusion that a hemodialysis session immediately after injection of a CM in chronic dialysis patients might be helpful...
Antiviral drug-induced nephrotoxicityHassane Izzedine
Department of Nephrology, Pitie Salpetriere Hospital, Paris, France
Am J Kidney Dis 45:804-17. 2005..In this article, we review the pathogenesis of antiviral drug-induced kidney injury, common nephrotoxic renal syndromes, and strategies for preventing kidney injury...
Oculorenal manifestations in systemic autoimmune diseasesHassane Izzedine
Department of Nephrology, Pitie Salpetriere Hospital, Paris, France
Am J Kidney Dis 43:209-22. 2004..Examination of the eye and kidney should be performed routinely in those diseases. This article reviews the major types of oculorenal manifestations in systemic autoimmune diseases...
Long-term renal function in liver transplant recipients and impact of immunosuppressive regimens (calcineurin inhibitors alone or in combination with mycophenolate mofetil): the TRY studySvetlana Karie-Guigues
Service de Nephrologie, Groupe Hospitalier de la Pitié Salpêtrière, Paris, France
Liver Transpl 15:1083-91. 2009..It seems likely that early intervention for CNI reduction is best for reducing the use of CNIs in the long term...
[Drugs renal toxicity]Svetlana Karie
Service de Nephrologie, Hopital Pitie Salpetriere, Boulevard de l Hopital, Paris, France
Nephrol Ther 6:58-74. 2010..Risk factors are also listed, such as high-risk populations, identification and elimination of risk factors, and drug dosage adjustment in patients with baseline abnormal renal function...
Renal safety of gadolinium-based contrast media in patients with chronic renal insufficiencyElena Ledneva
Information Conseil Adaptation Renal, Department of Nephrology, Hopital Pitie Salpetriere, 47 83, Boulevard de l Hopital, 75013 Paris, France
Radiology 250:618-28. 2009..This review surveys the literature with the purpose of clarifying the renal effects of gadolinium-based CM in patients with renal insufficiency...
Statins' dosage in patients with renal failure and cyclosporine drug-drug interactions in transplant recipient patientsVincent Launay-Vacher
Department of Nephrology, Pitie Salpetriere Hospital, 83, Boulevard de l Hopital, 75013 Paris, France
Int J Cardiol 101:9-17. 2005....
Lymphadenopathy and proteinuriaSvetlana Karie
Department of Nephrology, , Paris, France
Nephrol Dial Transplant 19:739-41. 2004
Drug-induced Fanconi's syndromeHassane Izzedine
Department of Nephrology, Pitie Salpetriere Hospital, Paris, France
Am J Kidney Dis 41:292-309. 2003..Acquired renal tubular defects resulting in FS also have been described in association with many exogenous agents, whether administered or accidentally ingested. This review concentrates on drug-induced FS...
[Drud-induced nephrotoxicity: Bibliography from January 2003 to December 2005]Svetlana Karie
ICAR, Service de Nephrologie, Groupe Hospitalier de la Pitié Salpêtrière, 83, Boulevard de l Hopital, 75015 Paris, France
Nephrol Ther 2:368-78. 2006..In this article, we present an updated version of the bibliography containing the case reports of nephrotoxicity published in the international literature from January 2003 to December 2005...
Pharmacokinetic considerations in the treatment of tuberculosis in patients with renal failureVincent Launay-Vacher
Department of Nephrology, Pitie Salpetriere Hospital, Paris, France
Clin Pharmacokinet 44:221-35. 2005..In the meantime, it could be generally advised to administer all antitubercular drugs after the haemodialysis session, even though some drugs are known to be non-dialysable...
Ear and kidney syndromes: molecular versus clinical approachHassane Izzedine
Department of Nephrology, Pitie Salpetriere Hospital, Paris, France
Kidney Int 65:369-85. 2004..Here, we describe ear and kidney clinical syndromes and their molecular expression...
Treatment of pain in patients with renal insufficiency: the World Health Organization three-step ladder adaptedVincent Launay-Vacher
Department of Nephrology, Pitie Salpetriere Hospital, Paris, France
J Pain 6:137-48. 2005..Perspective This well-known treatment strategy now adapted for use in patients with renal insufficiency should secure and rationalize pain treatment in those patients...
[Drug-induced nephrotoxicity: bibliography from January 2003 to December 2004]Svetlana Karie
Service de Nephrologie, Groupe Hospitalier Pitie Salpetriere, 83, Boulevard de l Hopital, 75015 Paris, France
Nephrol Ther 1:285-95. 2005..In this article, we present an updated version of the bibliography containing the case reports of nephrotoxicity published in the international literature from January 2003 to December 2004...
Renal tubular drug transportersVincent Launay-Vacher
Department of Nephrology, Pitie Salpetriere Hospital, Paris, France
Nephron Physiol 103:p97-106. 2006..Detailed information concerning molecular and cellular aspects of drug transporters expressed in the kidney has facilitated studies of the mechanisms underlying renal disposition as well as transporter-mediated drug interactions...
Abnormal blood pressure circadian rhythm: a target organ damage?Hassane Izzedine
Nephrology Department, Pitie Salpetriere Hospital, 47 83, Blvd de l Hopital, 75013, Paris, France
Int J Cardiol 107:343-9. 2006..These data suggest that patients in whom blood pressure decreases during the night incur less damage to their brain, kidneys, heart, and blood vessels than people with elevated nocturnal BP...
Evaluation of current practice: management of chemotherapy-related toxicitiesStéphanie Lheureux
Department of Clinical Research, Pitie Salpetriere Hospital, Paris, France
Anticancer Drugs 22:919-25. 2011..Albumin, creatinine clearance and lymphocyte should be routinely monitored at baseline to manage CT and to prevent their toxicities...
Angiotensin-converting enzyme inhibitor-induced syndrome of inappropriate secretion of antidiuretic hormone: case report and review of the literatureHassane Izzedine
Department of Nephrology, Pitie Salpetriere Hospital, Paris, France
Clin Pharmacol Ther 71:503-7. 2002..Severe symptomatic hyponatremia induced by the syndrome of inappropriate secretion of antidiuretic hormone should be considered a rare but possible complication associated with ACE inhibitor therapy...
Drug-induced glomerulopathiesHassan Izzedine
Pitie Salpetriere Hospital, Department of Nephrology, 47 83 boulevard de l Hopital, 75013 Paris, France
Expert Opin Drug Saf 5:95-106. 2006..This is, for instance, reflected in the fact that patients with drug-induced nephritic syndrome frequently have the HLA-B8 and DR3 antigens. In depth information is provided for the previously mentioned disorders...
Pharmacokinetics of tenofovir in haemodialysisHassane Izzedine
Department of Nephrology, , Paris, France
Nephrol Dial Transplant 18:1931-3. 2003
Eye and kidney: from clinical findings to genetic explanationsHassane Izzedine
Nephrology and Ophthalmology Departments, Pitie-Salpetriere Hospital, Paris, France
J Am Soc Nephrol 14:516-29. 2003
Why is a shrunken bladder and a nephrotic kidney an expression of the same disease?Sophie Georgin-Lavialle
Department of Nephrology, , Paris, France
Nephrol Dial Transplant 19:3193-5. 2004
Colony stimulating factors (CSF) biosimilars. Progress?Florian Scotte
European Hospital Georges Pompidou, 20, rue Leblanc, 75015 Paris, France
Target Oncol 7:S17-24. 2012..Many questions arise in connection with the marketing of several biosimilar drugs in the field of hematopoietic growth factors of white and red cells. Many of them should be discussed...
Inadequacy of antiretroviral drugs dosage adjustment in HIV patients receiving dialysisHassane Izzedine
Kidney Int 64:2324. 2003
Cetuximab pharmacokinetics in end-stage kidney disease under hemodialysisJuliette Thariat
J Clin Oncol 26:4223-5. 2008
International Society of Geriatric Oncology (SIOG) recommendations for the adjustment of dosing in elderly cancer patients with renal insufficiencyStuart M Lichtman
Memorial Sloan Kettering Cancer Centre, New York, USA
Eur J Cancer 43:14-34. 2007..Pharmacokinetic and pharmacodynamic data of anticancer agents in the elderly are needed in order to maximise efficacy whilst avoiding unacceptable toxicity...
Atazanavir: a novel inhibitor of HIV-protease in haemodialysisHassane Izzedine
Nephrol Dial Transplant 20:852-3. 2005
[Statins in patients with kidney failure: efficacy, tolerance, and prescription guidelines in patients with chronic kidney disease and renal transplant]Svetlana Karie
, , Paris
Presse Med 35:219-29. 2006..Their effectiveness in cardiovascular prevention in this population has not been demonstrated to date. Results about statin-induced kidney protection are encouraging but further and more specific studies are needed...
Thrombocytopenia induced by nicotinamide in hemodialysis patientsJacques B Rottembourg
Kidney Int 68:2911-2. 2005
Hemodialysis and ADAMTS-13Hassane Izzedine
Blood Purif 22:480. 2004
Beta-blocker-induced quadriparesisHassane Izzedine
Ann Intern Med 141:W62. 2004
Pharmacokinetics of tramadol in a hemodialysis patientHassane Izzedine
Nephron 92:755-6. 2002
Pharmacokinetics and dosage adjustment of rifabutin in a haemodialysis patientNader Bassilios
Nephrol Dial Transplant 17:531-2. 2002
