Research Topics
| Jacob C KoellaSummaryCountry: France Publications
| Collaborators
|
Detail Information
Publications
Coevolutionary interactions between host and parasite genotypesLouis Lambrechts
Laboratoire de Parasitologie Evolutive, CNRS UMR 7103, Universite Pierre et Marie Curie, CC 237, 7 quai St Bernard, 75252 Paris Cedex 05, France
Trends Parasitol 22:12-6. 2006..Moreover, not only the traits of the infection but also the genetic correlations among these and other traits that determine fitness might be controlled by interactions between host and parasite genotypes...- Experimental evaluation of the relationship between lethal or non-lethal virulence and transmission success in malaria parasite infectionsR E L Paul
Unité de Biochimie et Biologie Moléculaire des Insectes, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris, France
BMC Evol Biol 4:30. 2004..Thus, we additionally examine the relationship between anaemia and transmission in single and mixed clone infections... - [Evolutionary ecology and epidemiology of interactions between Anopheles mosquitoes and malaria]J C Koella
Laboratoire d Ecologie CC 237 Université P and M Curie, Paris
Schweiz Med Wochenschr 129:1106-10. 1999..Such an evolutionary view of malaria and mosquitoes will eventually lead to a better understanding of the epidemiology of malaria and may help to predict the effect of malaria control... - A model for the coevolution of immunity and immune evasion in vector-borne diseases with implications for the epidemiology of malariaJacob C Koella
Laboratoire de Parasitologie Evolutive, Centre National de la Recherche Scientifique, Unite Mixte de Recherche 7103, Universite Pierre et Marie Curie, 7 quai Saint Bernard, CC237, 75252 Paris, France
Am Nat 161:698-707. 2003..These results may help to explain the lack of encapsulated malaria parasites generally observed in natural populations of mosquito vectors, despite strong selection pressure for resistance in areas of very intense transmission... - Malaria as a manipulatorJacob C Koella
Laboratoire de Parasitologie Evolutive, , 7 quai St. Bernard, CC237, 75252 Paris, France
Behav Processes 68:271-3. 2005 - Effect of adult nutrition on the melanization immune response of the malaria vector Anopheles stephensiJ C Koella
Laboratoire de Parasitologie Evolutive, UMR 7103, Universite Pierre and Marie Curie, Paris, France
Med Vet Entomol 16:316-20. 2002..The observed interaction between these two resources indicates that both resources are required for the Anopheles female to develop an effective melanization immune response... - Epidemiological models for the spread of anti-malarial resistanceJ C Koella
Laboratoire de Parasitologie Evolutive, Université P, and M, Curie, CNRS UMR 7103, 7 quai St, Bernard CC237, 75252 Paris, France
Malar J 2:3. 2003.... - A genetic correlation between age at pupation and melanization immune response of the yellow fever mosquito Aedes aegyptiJacob C Koella
Laboratoire de Parasitologie Evolutive, CC237, Centre National de Recherche Scientifique, Universite P et M Curie, Paris, France
Evolution 56:1074-9. 2002..As a consequence, mosquitoes that respond to increased intense parasite pressure with more effective immunity are predicted to pay for the increased defense with slower development... - Direct and indirect immunosuppression by a malaria parasite in its mosquito vectorChristophe Boëte
Laboratoire de Parasitologie Evolutive, CNRS UMR 7103, Universite Pierre and Marie Curie, 7 quai Saint Bernard CC237, 75252 Paris Cedex 05, France
Proc Biol Sci 271:1611-5. 2004..As dead zygotes had no effect on encapsulation, this result demonstrates active suppression of the mosquito's immune response by malaria parasites... - The spatial spread of altruism versus the evolutionary response of egoistsJ C Koella
Laboratoire d Ecologie, CC237, Universite Pierre and Marie Curie, CNRS UMR 7625, Paris, France
Proc Biol Sci 267:1979-85. 2000..Perhaps most importantly, this approach shows that the ease with which altruism spreads in viscous populations is maintained despite countermeasures evolved by egoists... - Host genotype by parasite genotype interactions underlying the resistance of anopheline mosquitoes to Plasmodium falciparumLouis Lambrechts
Laboratoire de Parasitologie Evolutive, CNRS UMR 7103, Université P, and M, Curie, CC 237, 7 quai St Bernard, 75252 Paris Cedex 05, France
Malar J 4:3. 2005..In such systems, certain hosts are resistant to one subset of the parasite's genotypes, while other hosts are resistant to a different subset... - Malaria infection increases attractiveness of humans to mosquitoesRenaud Lacroix
Laboratoire de Parasitologie Evolutive, , Paris, France
PLoS Biol 3:e298. 2005..This ruled out the possibility of a bias due to differential intrinsic attractiveness of the children to mosquitoes and strongly suggests that gametocytes increase the attractiveness of the children... - Environmental influence on the genetic basis of mosquito resistance to malaria parasitesLouis Lambrechts
CNRS UMR 7103, Université Pierre et Marie Curie Paris, Parasitologie Evolutive, CC 237, CP52, 7 quai St Bernard, 75252 Paris Cedex 05, France
Proc Biol Sci 273:1501-6. 2006..e. the lines responded similarly to environmental variation. Overall, these results indicate that environmental variation can significantly reduce the importance of genes in determining the resistance of mosquitoes to malaria infection... - Effect of infection by Plasmodium falciparum on the melanization immune response of Anopheles gambiaeLouis Lambrechts
Laboratoire de Parasitologie Evolutive, Centre National de la Recherche Scientifique Université Pierre et Marie Curie, Paris, France
Am J Trop Med Hyg 76:475-80. 2007..falciparum relies on immune evasion rather than immuno-suppression to avoid being melanized and confirms that natural malaria transmission systems differ from laboratory models of mosquito-Plasmodium interactions... - Effects of shortened host life span on the evolution of parasite life history and virulence in a microbial host-parasite systemThibault Nidelet
UPMC University Paris 06, Laboratoire de Parasitologie Evolutive UMR 7103, 7 quai St Bernard, 75252 Paris, France
BMC Evol Biol 9:65. 2009..We simulated variation in host life span by killing hosts after 11 (early killing) or 14 (late killing) days post inoculation; after killing, parasite transmission stages were collected and used for a new infection cycle... - Genetic correlation between melanization and antibacterial immune responses in a natural population of the malaria vector Anopheles gambiaeLouis Lambrechts
Laboratoire de Parasitologie Evolutive, CNRS UMR 7103, Universite Pierre and Marie Curie, CC237, 7 quai St Bernard, 75252 Paris Cedex 05, France
Evolution 58:2377-81. 2004..Thus, our data do not support the idea of a trade-off among different outcomes of the invertebrate immune system, but rather that some families are overall immunologically superior to others... - Concurrent evolution of resistance and tolerance to pathogensOlivier Restif
Laboratoire de Parasitologie Evolutive, Centre National de la Recherche Scientifique, Unite Mixte de Recherche 7103, Universite Pierre et Marie Curie, 7 quai Saint Bernard, CC 237, 75252 Paris Cedex 05, France
Am Nat 164:E90-102. 2004..The latter result emphasizes the problems of estimating trade-offs and costs among natural populations without knowledge of the underlying mechanisms... - Shared control of epidemiological traits in a coevolutionary model of host-parasite interactionsOlivier Restif
Laboratoire de Parasitologie Evolutive, Centre National de la Recherche Scientifique Unité Mixte de Recherche 7103, Universite Pierre et Marie Curie, 7 quai Saint Bernard, CC 237, 75252 Paris Cedex 05, France
Am Nat 161:827-36. 2003..Third, the coevolutionary process may lead to decreasing the parasite's virulence as a response to a rise in the host's background mortality, contrary to classical predictions... - Reduced efficacy of the immune melanization response in mosquitoes infected by malaria parasitesC Boëte
Laboratoire de Parasitologie Evolutive, CNRS UMR 7103, Universite P and M Curie, Paris, France
Parasitology 125:93-8. 2002..In either case, the reduction of immunocompetence can have important consequences for malaria control, in particular for the current effort being invested into the genetic manipulation of mosquitoes... - A theoretical approach to predicting the success of genetic manipulation of malaria mosquitoes in malaria controlChristophe Boëte
Laboratoire de Parasitologie Evolutive, CNRS UMR 7103, Universite P and M Curie, Paris Cedex5, France
Malar J 1:3. 2002..However, we have only very little understanding of the conditions that would allow such genes to spread in natural populations... - Experimental evolution of specialization by a microsporidian parasiteMathieu Legros
Laboratoire de Parasitologie Evolutive, CNRS UMR 7103, Universite Pierre et Marie Curie Paris VI, 75005 Paris, France
BMC Evol Biol 10:159. 2010..The first regime was expected to lead to specialists, the other two to generalists. After 13 generations, we tested the evolved parasites on each of the four lines of the mosquito... - Host growth conditions regulate the plasticity of horizontal and vertical transmission in Holospora undulata, a bacterial parasite of the protozoan Paramecium caudatumOliver Kaltz
Laboratoire de Parasitologie Evolutive, CNRS UMR 7103, CC 237, Universite Pierre et Marie Curie, 7 quai St Bernard, 75252 Paris Cedex 5, France
Evolution 57:1535-42. 2003.... - Melanization of plasmodium falciparum and C-25 sephadex beads by field-caught Anopheles gambiae (Diptera: Culicidae) from southern TanzaniaAlex Schwartz
Department of Zoology, Institute of Biological Science, University of Aarhus, Universitetsparken, Denmark
J Med Entomol 39:84-8. 2002..However, C-25 beads do not accurately model An. gambiae's susceptibility to P falciparum oocysts in natural populations. To the best of our knowledge, this is the first report of field refractoriness in An. gambiae s.l... - Can transgenic mosquitoes afford the fitness cost?Louis Lambrechts
Department of Entomology, University of California, One Shields Avenue, Davis, CA 95616, USA
Trends Parasitol 24:4-7. 2008..Indeed, for the spread of a resistance transgene in a natural situation, the transgene's fitness cost and the efficacy of the gene drive will be more crucial than any evolutionary advantage... - A major genetic locus controlling natural Plasmodium falciparum infection is shared by East and West African Anopheles gambiaeMichelle M Riehle
Microbial and Plant Genomics Institute and Department of Microbiology, University of Minnesota, St Paul, MN 55108, USA
Malar J 6:87. 2007..An important question is whether genetic variation with respect to Plasmodium-resistance exists across Africa, and if so whether the same or multiple geographically distinct resistance mechanisms are responsible for the trait... - Population genetic structure of Plasmodium falciparum in the two main African vectors, Anopheles gambiae and Anopheles funestusZeinab Annan
Génétique et Evolution des Maladies Infectieuses, Unité Mixte de Recherche Institut de Recherche pour le Développement Centre National de la Recherche Scientifique 2724, B P 64501, 34394 Montpellier Cedex 5, France
Proc Natl Acad Sci U S A 104:7987-92. 2007.... - Anopheles gambiae immune responses to Sephadex beads: involvement of anti-Plasmodium factors in regulating melanizationEmma Warr
W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, 615 N. Wolfe Street, Baltimore, MD 21205-2179, USA
Insect Biochem Mol Biol 36:769-78. 2006.... - Sub-lethal effects of pathogens can lead to the evolution of lower virulence in multiple infectionsSolveig Schjørring
Department of Evolutionary Ecology, Max Planck Institute for Limnology, D 24306 Plon, Germany
Proc Biol Sci 270:189-93. 2003.... - Genetic variation of male reproductive success in a laboratory population of Anopheles gambiaeMaarten J Voordouw
Division of Biology, Imperial College of London, Silwood Park Campus, Ascot, Berkshire, UK
Malar J 6:99. 2007..For Anopheline mosquitoes, the vectors of human malaria, genetic variation in male reproductive success can have important consequences for any control strategy based on the release of transgenic or sterile males... - The role of evolution in the emergence of infectious diseasesRustom Antia
Department of Biology, Emory University, Atlanta, Georgia 30322, USA
Nature 426:658-61. 2003..Here we show that, as a consequence of this, the probability of pathogen evolution to R(0) > 1 and subsequent disease emergence can increase markedly... - Comparison of male reproductive success in malaria-refractory and susceptible strains of Anopheles gambiaeMaarten J Voordouw
Department of Biology, University of Victoria, PO Box 3020, Station CSC, Victoria, BC, V8W 3N5, Canada
Malar J 7:103. 2008....