Research Topics
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Publications
Global response of Plasmodium falciparum to hyperoxia: a combined transcriptomic and proteomic approachMarylin Torrentino-Madamet
UMR MD3 Université de la Méditerranée, Antenne IRBA de Marseille IMTSSA, Le Pharo, Allée du Médecin Colonel Eugène Jamot, BP 60109, 13262 Marseille cedex 07, France
Malar J 10:4. 2011..For example, the parasite circulates in human venous blood at 5% O2 pressure and in arterial blood, particularly in the lungs, at 13% O2 pressure. Moreover, the parasite is exposed to 21% O2 levels in the salivary glands of mosquitoes...
The oxidative stress in response to routine incremental cycling exercise in healthy sedentary subjectsYves Jammes
Service des Explorations Fonctionnelles Respiratoires, Hopital Nord, Assistance Publique Hopitaux de Marseille, Chemin des Bourrely, 13015 Marseille, France
Respir Physiol Neurobiol 144:81-90. 2004..They also show that the ROS production is proportional to the maximal aerobic power and inversely related to the consumption of plasma antioxidants...
Chronic fatigue syndrome: assessment of increased oxidative stress and altered muscle excitability in response to incremental exerciseY Jammes
Laboratoire de Physiopathologie Respiratoire UPRES EA 2201, Faculte de Medecine, Institut Federatif de Recherche Jean Roche, Marseille, France
J Intern Med 257:299-310. 2005....
Matched adaptations of electrophysiological, physiological, and histological properties of skeletal muscles in response to chronic hypoxiaMarion Faucher
Laboratoire de Physiopathologie Respiratoire, Institut Jean Roche, Faculte de Medecine, Universite de la Mediterranee, Bd Pierre Dramard, 13916 Marseille Cedex, France
Pflugers Arch 450:45-52. 2005..Reduced muscle use in hypoxia could explain the tendency for deteriorating adaptations in EDL, and the faster properties of SOL could result from hypoxia-induced inhibition of the growth-related fast-to-slow shift in muscle fibre types...
One-year occupational exposure to a cold environment alters lung functionYves Jammes
Respiratory Pathophysiology Laboratory, Faculte de Medecine Secteur Nord, Institut Jean Roche, Universite de la Mediterranee, Marseilles, France
Arch Environ Health 57:360-5. 2002..The authors concluded that 1 yr of daily exposure to a cold occupational environment elicits a modest--but significant--airflow limitation, accompanied by bronchial hyperresponsiveness, with the effects beginning within 6 mo of exposure...
Hyperbaric hyperoxia induces a neuromuscular hyperexcitability: assessment of a reduced response in elite oxygen diversYves Jammes
Laboratoire de Physiopathologie Respiratoire Unité Propre de Recherche de l Enseignement Supérieur Equipe d Accueil 2201, Institut Jean Roche, Universite de la Mediterranee, Marseille, France
Clin Physiol Funct Imaging 23:149-54. 2003..01 versus baseline). In O2 divers, similar HBO-induced M-wave changes were only observed when PiO2 was greater than 1.50 ATA. We conclude that HBO elicites neuromuscular hyperexcitability, attenuated in elite O2 divers...
Respiratory and circulatory effects of parietal pleural afferent stimulation in rabbitsYves Jammes
Laboratoire de Physiopathologie Respiratoire Unité Propre de Recherche de l Enseignement Supérieur, Equipe d Accueil 2201, Institut Jean Roche, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
J Appl Physiol 100:1539-46. 2006....
Inhaled NO and almitrine bismesylate in patients with acute respiratory distress syndrome: effect of noradrenalinL Papazian
Service de Reanimation, Hopital Sainte Marguerite, Marseille, France
Eur Respir J 14:1283-9. 1999..The present study confirmed that the combination of inhaled NO with almitrine bismesylate improved oxygenation, and demonstrated that almitrine bismesylate has no effect on oxygenation in patients receiving noradrenalin...
Statins alter oxidant-antioxidant status and lower exercise-induced oxidative stressS Delliaux
Aix Marseille Universite, IFR Jean Roche, Marseille, and Assistance Publique Hôpitaux de Marseille, Service des Explorations Fonctionnelles Respiratoires, Hopital Nord, Marseille, France
Int J Clin Pharmacol Ther 45:244-52. 2007..In conclusion, atorvastatin lowers resting oxidant-antioxidant activity: exercise-induced oxidative stress occurs mainly in muscles having a high oxidative capacity...
EMG changes in thigh and calf muscles in fin swimming exerciseY Jammes
Faculty of Medicine, UMR MD2 P2COE, Marseille, France
Int J Sports Med 31:548-54. 2010..Our most important finding is the persistence of the metaboreflex even in a situation of reduced muscle acidosis...
Inhaled nitric oxide and vasoconstrictors in acute respiratory distress syndromeL Papazian
Service de Reanimation, Service d Information Medicale, Hopital Sainte Marguerite, Marseille, France
Am J Respir Crit Care Med 160:473-9. 1999..The present results support the hypothesis that a selective pulmonary vasoconstrictor enhances the increase in oxygenation induced by inhaled NO, whereas norepinephrine attenuates this effect...
Does norepinephrine modify the effects of inhaled nitric oxide in septic patients with acute respiratory distress syndrome?L Papazian
Service de Reanimation Polyvalente, Hopital Sainte Marguerite, Marseille, France
Anesthesiology 89:1089-98. 1998..A prospective study compared the effects of nitric oxide on cardiorespiratory parameters, including the evaluation of right ventricular function in patients with ARDS and sepsis who were receiving or not receiving norepinephrine...
Chronic fatigue syndrome combines increased exercise-induced oxidative stress and reduced cytokine and Hsp responsesY Jammes
UMR MD2 P2COE, Faculte de Medecine, Universite de la Mediterranee, North Hospital, Assistance Publique Hopitaux de Marseille, France
J Intern Med 266:196-206. 2009....
Operation Everest III (Comex'97): the effect of simulated sever hypobaric hypoxia on lipid peroxidation and antioxidant defence systems in human blood at rest and after maximal exerciseP Joanny
INSERM U 501, Interactions Fonctionnelles en Neuroendocrinologie, Institut Jean Roche, , France
Resuscitation 49:307-14. 2001..01). These findings suggest that oxidative stress is induced by prolonged hypobaric hypoxia, and is maintained by rapid return to sea level, similar to the post-hypoxic re-oxygenation process. It is increased by physical exercise...
Electromyographic study of respiratory muscles during human diving at 46 ATAP Lenoir
Laboratoire de Biologie des Hautes Pressions, URA 1330 CNRS, Faculte de Medecine Nord, Marseille, France
Undersea Biomed Res 17:121-37. 1990..Hyperbaric tremor was recorded on the thoracic EMG and was maximal with He-O2 inhalation. It disappeared at the end of the period at 46 ATA (He-N2-O2)...
Effects of acute hypoxemia on force and surface EMG during sustained handgripE Dousset
, , Institut Jean Roche, , Boulevard Pierre Dramard, 13916 Marseille, France
Muscle Nerve 24:364-71. 2001..In addition, hypoxemia reduces the recruitment of slow firing motor unit, which are highly oxygen-dependent. This could constitute an adaptative muscle response to a reduced oxygen supply...
Depressed fatigue-induced oxidative stress in chronic hypoxemic humans and ratsJean Guillaume Steinberg
Laboratoire de Physiopathologie Respiratoire (UPRES EA 2201, Institut Jean Roche, , , Blvd. Pierre Dramard, 13916 cedex 20 Marseille, France
Respir Physiol Neurobiol 141:179-89. 2004..We concluded that chronic hypoxemia depressed the fatigue-induced oxidative stress, the effects prevailing in muscles having a high oxygen demand...
Changes in respiratory muscle activity in conscious cats during experimental dives at 101 ATAH Burnet
Laboratoire de Physiologie, 1330 Centre National de la Recherche Scientifique, Faculte de Medecine Nord, Marseille, France
J Appl Physiol 73:465-72. 1992..From 31 ATA, the H/L ratio decreased significantly in respiratory but not in skeletal muscles; this was associated with decreased MFCV in the diaphragm after several hours at maximal depth.(ABSTRACT TRUNCATED AT 250 WORDS)..
Influence of chronic hypoxemia on peripheral muscle function and oxidative stress in humansMarion Faucher
Laboratoire de Physiopathologie Respiratoire (EA 2201, , Institut Jean Roche, , Marseille, France
Clin Physiol Funct Imaging 24:75-84. 2004..Thus, we conclude that chronic hypoxemia exerts specific muscular effects: a reduced force production, an attenuated 'muscle wisdom', and the suppression of the exercise oxidative stress...
Assessment of an airway-to-pulmonary circulation reflex in catsP Barthelemy
Laboratoire de Physiopathologie Respiratoire, URA1630, Institut Jean Roche, Faculte de Medecine, Marseille, France
Neurosci Lett 211:89-92. 1996..The present observations demonstrate the existence of an airway-to-pulmonary circulation reflex, largely mediated through SLNs afferent pathways, the vagus nerve constituting the efferent arm of the reflex...
Fin swimming improves respiratory gas exchangeY Jammes
Faculty of Medicine, UMR MD2 P2COE, Marseille, France
Int J Sports Med 30:173-81. 2009..An attenuated chemoreflex drive to the heart and respiratory centres exerted by muscle metabolites might explain the depressed cardiopulmonary response to fin swimming...
Effect of long-term atorvastatin treatment on the electrophysiological and mechanical functions of muscleS Delliaux
Aix-Marseille 2 University, EA 2201, Institute Jean Roche, Faculty of Medicine, Marseille, France
Int J Clin Pharmacol Ther 44:251-61. 2006..These effects prevailed in muscles containing the largest proportion of slow-oxidative fibers and were associated with a reduced outward flow of potassium...
Pulmonary oedema in healthy SCUBA divers: new physiopathological pathwaysM Coulange
Service de Médecine Hyperbare, Pôle RUSH, Hopital Sainte Marguerite, Marseille, France
Clin Physiol Funct Imaging 30:181-6. 2010..The mechanism of immersion pulmonary oedema occurring in healthy divers is a matter of debate. Among consecutive injured divers admitted to our hyperbaric centre, we analysed prospective data about pulmonary oedema...
Is a short trial of prone positioning sufficient to predict the improvement in oxygenation in patients with acute respiratory distress syndrome?L Papazian
Service de Reanimation Medicale, Hĵpitaux Sud, Marseille, France
Intensive Care Med 27:1044-9. 2001..To determine whether a 1-h trial of prone positioning is sufficient to identify responders...
Exercise-induced inflammatory reaction affects electromyographic changes in skeletal muscle during dynamic contractions in humansM Gainnier
Laboratoire de Physiopathologie Respiratoire (EA 2201, Institut Jean-Roche, , , Marseille, France
Neurosci Lett 304:45-8. 2001..However, we noted that the slope of the MF vs. time regression line was halved after the 3-day ASA treatment which may indicate that inflammatory reactions are elicited by exhausting contractions and affect the EMG changes...
Changes in afferent activities from tibialis anterior muscle after nerve repair by self-anastomosisP Decherchi
Laboratoire de Physiopathologie Respiratoire (EA 2201, Institut Jean Roche, , , Boulevard Pierre Dramard, 13916 Marseille, France
Muscle Nerve 24:59-68. 2001....
Combination of two oxidant stressors suppresses the oxidative stress and enhances the heat shock protein 27 response in healthy humansChristelle Brerro-Saby
UMR MD2 P2COE, Faculte de Medecine, Universite de la Mediterranee, 13916 cedex 20 Marseille, France
Metabolism 59:879-86. 2010..8 +/- 9.2 ng/mL). Thus, the combination of 2 hits eliciting an oxidative stress seems to induce an adaptive Hsp27 response that might counterbalance an excessive production of reactive oxygen species...
Response of the rabbit diaphragm to tendon vibrationY Jammes
Laboratory of Respiratory Pathophysiology, University of the Mediterranean, Marseille, France
Neurosci Lett 290:85-8. 2000..These observations support the traditional view that the diaphragm is poorly endowed with muscle spindles and that these play little or no significant role in the act of breathing...
High or low doses of almitrine bismesylate in ARDS patients responding to inhaled NO and receiving norepinephrine?A Roch
Service de Reanimation Polyvalente, hopitaux Sud, Marseille, France
Intensive Care Med 27:1737-43. 2001....
Motor and sensory re-innervation of the lung and heart after re-anastomosis of the cervical vagus nerve in ratsFabienne Bregeon
Laboratoire de Physiopathologie Respiratoire EA 2201, Institut Federatif de Recherche Jean Roche, Faculte de Medicine, Universite de la Mediterranee, Marseille, France
J Physiol 581:1333-40. 2007..Our study demonstrates the capacity of pulmonary vagal sensory neurones to regenerate after axotomy followed by re-anastomosis, and the failure of the vagal efferents to re-innervate both the lungs and heart...
Reliability of different blood indices to explore the oxidative stress in response to maximal cycling and static exercisesJean Guillaume Steinberg
Service des Explorations Fonctionnelles Respiratoires, , , Institut Jean Roche, , France
Clin Physiol Funct Imaging 26:106-12. 2006..In addition, TAS measurement does not seem to represent a reliable and unique tool to explore exercise-induced oxidative stress, at least during isometric efforts that allow the muscle to work under anaerobic condition...
Consequences of prolonged total thermoneutral immersion on muscle performance and EMG activityMathieu Coulange
Laboratoire de Physiopathologie Respiratoire EA 2201, Institut Jean Roche, Faculte de Medecine, Universite de la Mediterranee, Bd Pierre Dramard, 13920, Cedex 20 Marseille, France
Pflugers Arch 455:903-11. 2008....
Enhanced exercise-induced plasma cytokine response and oxidative stress in COPD patients depend on blood oxygenationYves Jammes
Lung Function Laboratory, North Hospital, Assistance Publique Hopitaux de Marseille, Marseille, France
Clin Physiol Funct Imaging 28:182-8. 2008..Our study indicates that the PaO2 level affects both the exercise-induced oxidative stress and cytokine response in hypoxemic COPD patients...
Fatigue-induced changes in tonic vibration response (TVR) in humans: relationships between electromyographic and biochemical eventsChristelle Brerro-Saby
UMR MD2, Physiologie et Physiopathologie en Conditions d Oxygénation Extrêmes, Institut Jean Roche, Faculte de Medecine, Universite de la Mediterranee, Bd Pierre Dramard, 13916, Marseille, France
Muscle Nerve 38:1481-9. 2008..The origin of TVR changes after muscle fatigue is questioned because the relationship between TVR depression and LA accumulation might be temporal, not causal, and changes in muscle stiffness were not explored...
Neuromuscular rehabilitation by treadmill running or electrical stimulation after peripheral nerve injury and repairTanguy Marqueste
, , , , 13288 Marseille Cedex 09, France
J Appl Physiol 96:1988-95. 2004..e., the discharge pattern was similar to the C group). The effectiveness of the chronic electromyostimulation and the treadmill exercise on afferent recovery is discussed with regard to parameters listed above...
Comparison between the effects of chronic and acute hypoxemia on muscle afferent activities from the tibialis anterior muscleErick Dousset
, , , , Marseille, France
Exp Brain Res 148:320-7. 2003..Our data also suggest that chronic hypoxemia depresses mechanosensitive muscle afferents. This may explain the observation that sensorimotor control of skeletal muscles is often markedly impaired in hypoxemic humans...
[Cardiovascular function in man during experimental dives at 26 ATA (helium-nitrogen-oxygen mixture)]P Barthelemy
Laboratoire de Physiologie, URA 1330 CNRS, Faculte de Medecine, Marseille, France
Arch Int Physiol Biochim Biophys 101:341-5. 1993..These observations are discussed in terms of enlarged sensitivity of the baroreflex arch under hyperbaric condition...
Identification and properties of parietal pleural afferents in rabbitsYves Jammes
Laboratoire de Physiopathologie Respiratoire UPRES EA 2201, Faculte de Medecine, Boulevard Pierre Dramard, 13916 Cedex 20, Marseille, France
J Physiol 567:641-50. 2005..Thus, sensory endings connected with thin myelinated and unmyelinated fibres in the internal intercostal nerve detect the mechanical and chemical events of pleural diseases...
The post-exercise oxidative stress is depressed by acetylsalicylic acidJean Steinberg
Laboratoire de Physiopathologie Respiratoire (UPRES EA 2201, , Institut Jean Roche, , Boulevard Pierre Dramard, 13916 Marseille, France
Respir Physiol Neurobiol 130:189-99. 2002....
Acute hypoxemia does not increase the oxidative stress in resting and contracting muscle in humansErick Dousset
, , , Marseille, France
Free Radic Res 36:701-4. 2002..We conclude that acute hypoxemia does not modify the production of oxygen free radicals after strenuous static efforts and even seems to attenuate the lipid peroxidation...
Effects of chronic hypoxemia on the afferent nerve activities from skeletal muscleE Dousset
Laboratoire de Physiopathologie Respiratoire (UPRES EA, Institut Jean Roche, , , Marseille, France
Am J Respir Crit Care Med 164:1476-80. 2001..These results suggest that chronic hypoxemia markedly alters the chemosensitivity of the group III-IV muscle afferents, which may explain the higher fatigability of hypoxemic subjects...
Interindividual variability of surface EMG changes during cycling exercise in healthy humansY Jammes
, Institut Jean Roche, , , 13916 cedex 20 Marseille, France
Clin Physiol 21:556-60. 2001..These data suggest that the interpretation of M-wave changes during cycling must take into consideration the sport practices of the subjects and also that SEMG power spectrum and M-wave explore different electrophysiological events...
Combined in situ analysis of metabolic and myoelectrical changes associated with electrically induced fatigueJ L Darques
Laboratoire de Physiopathologie Respiratoire, UPRES EA 2201, Institut Jean Roche, Faculte de Medecine, Universite de la Mediterranee, Bd Pierre Dramard, 13916 Marseille Cedex 20, France
J Appl Physiol 95:1476-84. 2003..Finally, our results further indicate a reduction of energy cost of contraction when stimulation frequency is increased from 10 to 100 Hz...
Activation of respiratory afferents by resistive loaded breathing modifies somatosensory evoked potentials to median nerve stimulation in humansE Balzamo
INSERM CJF 97 06, Laboratoire de Neurophysiologie and Neuropsychologie, Faculté de Médecine La Timone 27, Marseille, France
Neurosci Lett 270:157-60. 1999..Thus, respiratory afferents very likely interact with pathways of the somatosensory system...
Electromyographic signs of neuromuscular fatigue are concomitant with further increase in ventilation during static handgripF Hug
Laboratoire de Physiopathologie Respiratoire (EA 2201, Institut Jean Roche, , Marseille, France
Clin Physiol Funct Imaging 24:25-32. 2004..Neurogenic factors seem to be responsible for the two responses which persist despite the absence of any release of metabolites in the circulation...
Reactive oxygen species and inflammatory mediators enhance muscle spindles mechanosensitivity in ratsStephane Delliaux
UMR MD2, Physiologie et Physiopathologie en Conditions d Oxygénation Extrêmes, Faculté de Médecine IFR Jean Roche, Universite de la Mediterranee, Boulevard Pierre Dramard, 13916, Marseille, Cedex 20, France
Pflugers Arch 457:877-84. 2009..H2O2 injection and MS elicited significant and similar increases in isoprostanes and IL-6. We report a direct modulation of muscle spindles mechanosensitivity by ROS and inflammatory mediators...
The changes in neuromuscular excitability with normobaric hyperoxia in humansChristelle Brerro-Saby
Faculte de Medecine, Universite de la Mediterranee, UMR MD2P2COE Boulevard Pierre Dramard, Marseille 13916, Cedex 20, France
Exp Physiol 95:153-9. 2010..The activation of the group IV muscle afferents by hyperoxia and the resulting oxidative stress might explain the TVR depression...
Physiological, histological and biochemical properties of rat skeletal muscles in response to hindlimb suspensionChantal Guillot
Laboratoire de Physiopathologie Respiratoire EA 2201, Institut Jean Roche, Faculte de Medecine Nord, Bd Pierre Dramard, 13916 Marseille, France
J Electromyogr Kinesiol 18:276-83. 2008..This strongly suggests that hypoxemia reduces the ROS production independently from any muscle disuse...
Reliability of burst superimposed technique to assess central activation failure during fatiguing contractionErick Dousset
Laboratoire des Déterminants Physiologiques de l Activité Physique UPRES EA3285, Institut Fédératif de Recherche E J Marey IFR 107, Universite de la Mediterranee Aix Marseille II, Cedex 09, 13288 Marseille, France
J Electromyogr Kinesiol 13:103-11. 2003..These observations indicate that an absence of superimposed electrically-induced muscle contraction does not allow us to conclude the existence of a sole peripheral muscle fatigue in these circumstances...
Effects of neonatal capsaicin deafferentation on neuromuscular adjustments, performance, and afferent activities from adult tibialis anterior muscle during exerciseErick Dousset
, , , Marseille, France
J Neurosci Res 76:734-41. 2004....
Reflex relationships between the cervical esophagus and the respiratory system in catsP Barthelemy
Laboratoire de Physiopathologie Respiratoire, Faculte de Medecine, Marseille, France
Neurosci Lett 217:81-4. 1996..The vagus nerve is the efferent arm of the bronchomotor reflex whereas modulation of the sympathetic control of pulmonary circulation seems to be responsible for the changes in pulmonary hemodynamics...
Passive expiratory flow-volume curve is not an accurate method to measure the respiratory time constant in rabbitsR Vialet
Department of Anesthesia and Critical Care, Centre Hospitalier Universitaire, , Marseille, France
Acta Anaesthesiol Scand 43:1017-20. 1999..CONCLUSIONS: The end-inspiratory occlusion technique leads to a systemic bias in measurements of respiratory time constant, especially when the resistance of the respiratory system is elevated...
Reactive oxygen species activate the group IV muscle afferents in resting and exercising muscle in ratsStephane Delliaux
UMR MD2 P2COE, IFR Jean Roche, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
Pflugers Arch 459:143-50. 2009..We concluded that ROS influence both the spontaneous and contraction-induced activities of the group IV muscle afferents and are a potent stimulus of muscle metaboreceptors...
Post-exercise heart rate recovery in healthy, obeses, and COPD subjects: relationships with blood lactic acid and PaO2 levelsAbdoulaye Ba
UMR MD2 P2COE, IFR Jean Roche, Faculty of Medicine, University of Mediterranee, Bd Pierre Dramard, 13916, Marseille Cedex 20, France
Clin Res Cardiol 98:52-8. 2009..The mechanisms of delayed post-exercise HR recovery are only suspected because significant correlations cannot assess cause-to-effect relationships...
Cytokine and oxidative responses to maximal cycling exercise in sedentary subjectsJean Guillaume Steinberg
Lung Function Laboratory, North Hospital, Assistance Publique Hopitaux de Marseille, and Faculty of Medicine, Universite de la Mediterranee, Marseille, France
Med Sci Sports Exerc 39:964-8. 2007..The simultaneous determination of the time course and magnitude of oxidative stress indicators and cytokine changes elicited by maximal incremental exercise has not yet been published for healthy sedentary subjects...
Eccentric exercise alters muscle sensory motor control through the release of inflammatory mediatorsTanguy Marqueste
Laboratoire des Determinants Physiologiques de l'Activite Physique, , , , 13288 Marseille Cedex 09, France
Brain Res 1023:222-30. 2004..Such an altered sensori-motor control, accompanying the post-eccentric inflammatory syndrome, could play a key role in deterioration of muscle performance and of its voluntary activation...
Interactions between endogenous nitric oxide and hypoxemia in activation of group IV muscle afferentsSandrine Arbogast
Laboratoire de Physiopathologie Respiratoire, , Equipe d'Accueil 2201, Institut Jean Roche, , , Boulevard Pierre Dramard, 13916 Marseille, France
Muscle Nerve 26:194-200. 2002..Our data anticipate the neuromuscular side effects of treatments using exogenous NO or drugs acting on endogenous NO production...
Electromyographic tools to assess hemidiaphragm paralysisYves Jammes
UMR MD2 P2COE, Jean Roche Institute, Faculty of Medicine, University of Mediterranee, Marseille, France
Clin Physiol Funct Imaging 30:107-15. 2010..Thus, the combination of measurements of phrenic nerve CT and Edi recordings during voluntary inspiratory efforts confirmed 67% of the radiographic suspicion of diaphragmatic dysfunction...
Consequences of prolonged total body immersion in cold water on muscle performance and EMG activityMathieu Coulange
Laboratoire de Physiopathologie Respiratoire (EA 2201, Institut Jean Roche, , , Marseilles, France
Pflugers Arch 452:91-101. 2006....
Evidence that free radical generation occurs during scorpion envenomationE Dousset
, , , , Marseille, France
Comp Biochem Physiol C Toxicol Pharmacol 140:221-6. 2005..We therefore conclude that free radical generation only plays a minor role in the toxicity of scorpion venom...
Training to yoga respiration selectively increases respiratory sensation in healthy manFlorence Villien
Laboratoire de Physiopathologie Respiratoire (EA 2201, Institut Jean Roche, , , F-13916 Marseille Cedex 20, France
Respir Physiol Neurobiol 146:85-96. 2005..These data suggest that training to yoga respiration selectively increases the respiratory sensation, perhaps through its persistent conditioning of the breathing pattern...
Persistence of diaphragmatic contraction influences the pulmonary inflammatory response to mechanical ventilationFabienne Bregeon
Laboratoire de Physiopathologie Respiratoire EA 2201, Institut Jean Roche, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
Respir Physiol Neurobiol 142:185-95. 2004....
Mechanical ventilation affects lung function and cytokine production in an experimental model of endotoxemiaFabienne Bregeon
Laboratoire de Physiopathologie Respiratoire EA 2201 Institut Jean Roche, Faculte de Medecine, Universite de la Mediterranee, and Centre Hospitalier Universitaire CHU Nord, Marseille, France
Anesthesiology 102:331-9. 2005..In this study, the authors investigated whether this strategy would result in lung injury during transient endotoxemia in the lungs of healthy animals...
Surface diaphragmatic electromyogram changes after laparotomyStephane V Berdah
Laboratoire de Physiopathologic Respiratoire EA2201, Institut Jean Roche, Faculte de Medecine, Marseille, France
Clin Physiol Funct Imaging 22:157-60. 2002..These modifications are compatible with an altered diaphragmatic excitability and/or a reduced central drive to the diaphragm...
High prevalence of reversible airway obstruction in asbestos-exposed workersStephane Delpierre
Laboratoire de Physiopathologie Respiratoire, Institut Jean Roche, , , Marseille, France
Arch Environ Health 57:441-5. 2002..It is hoped that the observations in this study will encourage practitioners to check for RAO in asbestos workers who use inhaled bronchodilators...
Long-term outcome in chest traumaMarc Leone
Hopital Nord, Assistance Publique Hopitaux de Marseille, Marseille, France
Anesthesiology 109:864-71. 2008..Here, the authors sought to describe chest trauma survivor outcomes 6 months and 1 yr after discharge from the intensive care unit, paying special attention to pulmonary outcomes...
Respiratory and cardiovascular responses evoked by tibialis anterior muscle afferent fibers in ratsPatrick Decherchi
Laboratoire des Déterminants Physiologiques de l Activité Physique UPRES EA 3285, Universite de la Mediterranee Aix Marseille II, 13288, Marseille Cedex 09, France
Exp Brain Res 183:299-312. 2007..No change was observed after nerve section. Our data indicate that changes occurring in rat hindlimb muscle such as the tibialis anterior are sufficient to regulate the cardiorespiratory function via metabosensitive fiber activation...
Breath-hold training of humans reduces oxidative stress and blood acidosis after static and dynamic apneaFabrice Joulia
Laboratoire d'Ergonomie Sportive et Performance (EA 20548, U.F.R. STAPS, , 83130 La Garde cedex, France
Respir Physiol Neurobiol 137:19-27. 2003..After dynamic apnea, the blood acidosis was reduced and the oxidative stress no more occurred. These results suggest that the practice of breath-holding improves the tolerance to hypoxemia independently from any genetic factor...
Reduced oxidative stress and blood lactic acidosis in trained breath-hold human diversFabrice Joulia
Laboratoire d'Ergonomie du Sport et de la Performance Motrice, UFR STAPS, , Toulon, France
Respir Physiol Neurobiol 133:121-30. 2002..Thus, human subjects involved in a long duration training programme of breath-hold diving have reduced post-apnea as well as post-exercise blood acidosis and oxidative stress, mimicking the responses of diving animals...
Changes in neuromuscular function after training by functional electrical stimulationTanguy Marqueste
, , , Boulevard Pierre Dramard, 13916 Marseille, France
Muscle Nerve 28:181-8. 2003..These data indicate that FES improves muscle function and elicits changes in central muscle activation. The benefits of FES were greater in FDB, which is highly fatigable, and persisted for at least a 6-week period...
