Research Topics
| J L WautierSummaryAffiliation: Institut National de la Transfusion Sanguine Country: France Publications
| Collaborators
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Detail Information
Publications
N(carboxymethyl)lysine as a biomarker for microvascular complications in type 2 diabetic patientsM P Wautier
INSERM U76, Paris, France
Diabetes Metab 29:44-52. 2003..We investigated whether serum levels of AGEs and of the glycoxidation compound carboxymethyl-lysine (CML) were increased and correlated with vascular complications in type II diabetes mellitus...- [Evaluation of scientific and medical articles]J L Wautier
INTS, 6, rue Alexandre Cabanel, 75739 cedex 15, Paris, France
Transfus Clin Biol 9:359-61. 2002..Impact factor is an indicator of citation but not of the quality of an article and should not be used as a unique criterion for evaluating the quality of medical or scientific research works... - Blood cells and vascular cell interactions in diabetesJ L Wautier
Laboratoire de Biologie Vasculaire et Cellulaire, Paris 7, INSERM U76, France
Clin Hemorheol Microcirc 25:49-53. 2001..Recombinant RAGE administration corrected vascular hyperpermeability and prevented the development of atherosclerosis in the animals... - Advanced glycation end products, their receptors and diabetic angiopathyJ L Wautier
Laboratoire de Biologie Vasculaire et Cellulaire, UFR Lariboisière St Louis, Universite Paris 7 Denis Diderot
Diabetes Metab 27:535-42. 2001..These data suggest a central role of AGEs and RAGE in the development of chronic complications of diabetes... - [Drug-induced hemolytic anemia]J L Wautier
Institut National de la Transfusion Sanguine, 6, rue Alexandre Cabanel, 75015 Paris, France
Transfus Clin Biol 8:377-80. 2001..Hemolytic-uremic syndrome can be provoked by different drugs including immunodulators but the mechanism provoking hemolysis remains unclear... - Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGEM P Wautier
Laboratoire de Biologie Vasculaire et Cellulaire, Hopital Lariboisiere, Paris, France 75475
Am J Physiol Endocrinol Metab 280:E685-94. 2001..These findings underscore a central role of NADPH oxidase in AGE-RAGE-mediated generation of ROS and provide a mechanism for altered gene expression in AGE-related disorders... - Measurement of leukocyte rheology in vascular disease: clinical rationale and methodology. International Society of Clinical HemorheologyJ L Wautier
Institut National de la Transfusion Sanguine, Paris, France
Clin Hemorheol Microcirc 21:7-24. 1999..In the second part of the article, possible technical approaches are presented and possible avenues for leukocyte rheological investigations are discussed... - Cultured endothelial cells from human arteriovenous malformations have defective growth regulationM P Wautier
Laboratoire de Biologie Vasculaire et Cellulaire, Unité de Formation et de Recherche Lariboisière St Louis, Paris 7, INTS, Paris, France
Blood 94:2020-8. 1999..The low response to cytokines, the higher propensity to proliferate, and the ets-1 expression suggest that AMEC have a defective regulation of proliferation that may be due to a reduced apoptotic process... - Role of Lu/BCAM in abnormal adhesion of sickle red blood cells to vascular endotheliumW El Nemer
INSERM U665, 75015 Paris, France
Transfus Clin Biol 15:29-33. 2008.... - Mesothelial RAGE activation by AGEs enhances VEGF release and potentiates capillary tube formationE Boulanger
Vascular and Cellular Biology Laboratory, Institut National de la Transfusion Sanguine, University of Paris7 Denis Diderot, Paris, France
Kidney Int 71:126-33. 2007..05 and P<0.001, respectively. In a co-culture system, we showed that VEGF production by HPMC favors capillary tube formation through mesothelial RAGE activation and could explain neoangiogenesis in PD patient... - Severity of diabetic microvascular complications is associated with a low soluble RAGE levelN Grossin
Cellular and Vascular Biology, INTS, France
Diabetes Metab 34:392-5. 2008..In the present study, we measured blood levels of sRAGE and CML-protein in diabetic patients with and without microvascular complications... - Immortalized human endothelial cells have a decreased response to IL-1 secondary to an IL-1 receptor defective expression restored by corticosteroidsM P Wautier
Laboratoire de Biologie Vasculaire et Cellulaire, , Paris 7, INTS, France
Cell Biol Toxicol 15:153-61. 1999..This alteration may be improved by addition of corticosteroids to the cell culture, which extends the possibility of using IVEC as a model of endothelial cells... - Postprandial hyperglycemia alters inflammatory and hemostatic parametersJ L Wautier
Biologie Vasculaire et Cellulaire, Institut National de la Transfusion Sanguine, France
Diabetes Metab 32:2S34-6. 2006..All the modifications observed in the postprandial phase are not too deleterious but their iterative characteristics may lead to vascular dysfunction... - Advanced glycation end products regulate extracellular matrix protein and protease expression by human glomerular mesangial cellsJ Berrou
INSERM U702, Hopital Tenon AP HP, Paris, France
Int J Mol Med 23:513-20. 2009..Inhibition of AGE receptors or neutralization of the protease inhibitors TIMP-3 and PAI-1 could represent an important new therapeutic strategy for diabetic nephropathy... - [French training program for medical students in transfusion medicine. Transfusion Medicine Teachers' College]J L Wautier
Secrétariat du CETS, 6, rue Alexandre Cabanel, 75739 Paris cedex 15, France
Transfus Clin Biol 12:59-69. 2005..The following recommendations are not strict guidelines but is a common basis which will be improved in 2005 according to new evidence based transfusion medicine... - Red blood cell phosphatidylserine exposure is responsible for increased erythrocyte adhesion to endothelium in central retinal vein occlusionM P Wautier
INSERM, UMRS665, Paris, France
J Thromb Haemost 9:1049-55. 2011..Increased red blood cell (RBC) adhesion has been associated with vascular complications in several diseases, such as sickle cell anemia, diabetes mellitus or polycythemia vera... - Leukocyte adhesion to endothelial cellsJ L Wautier
U 150 INSERM, URA 334 CNRS, , Paris, France
Biorheology 27:425-32. 1990..Therefore, the modulation of leukocyte-endothelial cell interactions is a possible target for antithrombotic and antiatherosclerotic therapy... - Recombinant advanced glycation end product receptor pharmacokinetics in normal and diabetic ratsC Renard
Laboratoire de Recherche en Biologie Vasculaire et Cellulaire, Universite Paris 7, Hopital Lariboisiere, France
Mol Pharmacol 52:54-62. 1997..94 and 3.24 liter/kg, respectively; p = 0.049). Our study showed that rR-RAGE was biologically active in vivo and slowly cleared, which suggests it could be considered as a potential therapy... - Mechanical properties of bovine aortic endothelial cells in suspension studied by ultrasonic interferometryM Boynard
Groupe de Recherche en Physique et Biophysique, UFR Biomedicale, Universite Paris V, 45 Rue des Saintes Pères, 75006, Paris, France
Eur J Ultrasound 12:81-8. 2000.... - An in vitro system for testing leucocyte and leukaemic cell line adhesion to synthetic fibresL L Barbe
Laboratoire de Biologie Vasculaire et Cellulaire, Paris, and Institut National de la Transfusion Sanguine (INTS, , Paris, France
Br J Haematol 115:664-71. 2001..Lymphocytes or lymphocytic cell lines were poorly adherent to PET fibres. The retaining capacity of leucocyte filters can be improved by taking into account the different parameters for the design of new filters.. - [Advanced glycosylation end products (AGE): new toxins?]E Boulanger
Laboratoire de Recherche en Biologie Vasculaire et Cellulaire, INTS, Paris
Nephrologie 23:351-9. 2002..New drugs are tested to reduce AGEs or AGE deleterious effects but the best treatment remains the prevention of AGE formation by a strict glycemic control... - [Molecular basis of red blood cell adhesion to endothelium]J L Wautier
Universite Paris Diderot Paris 7, 75013 Paris, France
Ann Pharm Fr 69:3-6. 2011..The couple laminin alpha 5 endothelial and phosphorylated Lu/BCAM explained the increased adhesion of RBCs from patients PV to endothelium... - [Andragogy: reality or utopy]J L Wautier
INTS, 6, rue Alexandre Cabanel, 75739 Paris cedex 15, France
Transfus Clin Biol 11:169-72. 2004..Andragogy has lead to the development of several approaches to improve continuous education. Several tools and methodologies have been created for adult education... - Red cell and endothelial Lu/BCAM beyond sickle cell diseaseY Colin
Inserm UMR_S 665, Institut National de la Transfusion Sanguine, 6, rue Alexandre Cabanel, 75015 Paris, France
Transfus Clin Biol 15:402-5. 2008..All these results further illustrate that minor blood group antigens might have important role under physiological and physiopathological conditions in erythroid and non erythroid tissues as well... - [Electronic learning: interactive learning in medicine or Socrates in electronic guise]J L Wautier
Institut National de la Transfusion Sanguine, Paris, France
Transfus Clin Biol 12:150-2. 2005..Several electronic companies have given a free access to the programmes and sites. The use of electronic media leads to an adaptation of teaching methods making them more interactive... - [Indications for transfusions of labile blood products]J L Wautier
Institut National de la Transfusion Sanguine, 6, rue Alexandre Cabanel, 75015 Paris, Paris
Transfus Clin Biol 12:56-8. 2005..Fresh frozen plasma has now a limited use, only in complex haemostatic disorders and in hemolytic uremic syndrome... - A new dark side of the Maillard's productsJ L Wautier
Diabetes Metab 29:86-7. 2003