Research Topics
Species | H LaudeSummaryAffiliation: Institut National de la Recherche Agronomique Country: France Publications
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Detail Information
Publications
The sialic acid binding activity of the S protein facilitates infection by porcine transmissible gastroenteritis coronavirusChristel Schwegmann-Wessels
Institute for Virology, University of Veterinary Medicine Hannover, Bunteweg 17, 30559 Hannover, Germany
Virol J 8:435. 2011....
Brain transcriptional stability upon prion protein-encoding gene invalidation in zygotic or adult mouseSead Chadi
INRA, UMR1313, Génétique Animale et Biologie Intégrative, F 78350, Jouy en Josas, France
BMC Genomics 11:448. 2010..To potentially assess this conundrum, we performed a comparative transcriptomic analysis of the brain of wild-type mice with that of transgenic mice invalidated at this locus either at the zygotic or at the adult stages...
[Newly discovered forms of prion diseases in ruminants]H Laude
INRA, U892, Virologie Immunologie Moléculaires, Domaine de Vilvert, 78350 Jouy en Josas, France
Pathol Biol (Paris) 57:117-26. 2009..This review is aimed at summarising the current knowledge on these newly recognised forms of ruminants TSEs, and at discussing their possible origin and potential implications in terms of animal and human health...
Ex vivo propagation of infectious sheep scrapie agent in heterologous epithelial cells expressing ovine prion proteinD Vilette
Unité de Virologie Immunologie Moléculaires, Institut National de la Recherche Agronomique, 78350 Jouy en Josas, France
Proc Natl Acad Sci U S A 98:4055-9. 2001..This approach led to the ex vivo propagation of a natural transmissible spongiform encephalopathy agent (i.e., without previous experimental adaptation to rodents) and might be applied to human or bovine prions...
Transmissible gastroenteritis coronavirus induces programmed cell death in infected cells through a caspase-dependent pathwayJ F Eleouet
Unite de Virologie et Immunologie Moleculaires, Institut National de la Recherche Agronomique, 78350 Jouy en Josas, France
J Virol 72:4918-24. 1998..NF-kappaB DNA binding was shown to be strongly and quickly induced by TGEV infection. However, transcription factor decoy experiments showed that NF-kappaB activation is not critical for TGEV-induced apoptosis...
Establishment of astrocyte cell lines from sheep genetically susceptible to scrapieD Vilette
Unité de Virologie Immunologie Moléculaires, Institut National de la Recherche Agronomique, Jouy en Josas, France
In Vitro Cell Dev Biol Anim 36:45-9. 2000..Therefore, they could be attractive tissue culture models for the study of propagation and pathogenesis of the scrapie agent ex vivo...
Reconstituted coronavirus TGEV virosomes lose the virus ability to induce porcine interferon-alpha productionS Riffault
Virologie et Immunologie Moléculaires, INRA, Jouy en Josas, France
Vet Res 28:77-86. 1997..These data indicated that IFN-alpha inducing interactions between TGEV external proteins and leukocytes required a complex native envelope protein structure which has been lost in the virosomes...
Reconstituted coronavirus TGEV virosomes lose the virus ability to induce porcine interferon-alpha productionS Riffault
Virologie et Immunologie Moléculaires, INRA, Jouy en Josas, France
Vet Res 28:105-14. 1997..These data indicated that IFN-alpha inducing interactions between TGEV external proteins and leukocytes required a complex native envelope protein structure which has been lost in the virosomes...
Aminopeptidase N is a major receptor for the entero-pathogenic coronavirus TGEVB Delmas
Unite de Virologie et Immunologie Moleculaires, INRA, Jouy en Josas, France
Nature 357:417-20. 1992..First, virions bound specifically to aminopeptidase N that was purified to homogeneity. Second, recombinant expression of aminopeptidase N conferred infectivity by TGEV to an otherwise non-permissive cell line...
Porcine respiratory coronavirus: molecular features and virus-host interactionsH Laude
INRA, Unite de Virologie et Immunologie Moleculaires, Jouy en Josas, France
Vet Res 24:125-50. 1993..The authors' views concerning the impact of the emergence of PRCV on both coronavirus research and swine production are presented in the conclusion...
Unexpected high testis-specific transcriptional activity of the cyclin T1 promoter in transgenic miceX Mata
Laboratoire de Génétique Biochimique et de Cytogénétique, INRA, 78352 Cedex, Jouy en Josas, France
FEBS Lett 549:163-6. 2003..Both constructs resulted in the unexpected high male germ cell-specific expression of the prion protein. These data re-question the suspected location of the cyclin T1 gene regulatory elements...
A cell line infectible by prion strains from different speciesM P Courageot
Virologie et Immunologie Moléculaires, INRA, 78350 Jouy en Josas, France
J Gen Virol 89:341-7. 2008..Such an approach may facilitate investigations of the molecular basis of strain identity and prion diversity...
