F Bourdeaut

Summary

Affiliation: Institut Curie
Country: France

Publications

  1. ncbi Germline mutations of the paired-like homeobox 2B (PHOX2B) gene in neuroblastoma
    Franck Bourdeaut
    Laboratoire de Pathologie Moléculaire des Cancers, INSERM U 509, Institut Curie, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    Cancer Lett 228:51-8. 2005
  2. ncbi Alagille syndrome and nephroblastoma: Unusual coincidence of two rare disorders
    Franck Bourdeaut
    Institut Curie, Departement de Pediatrie, Paris F 75246, France
    Pediatr Blood Cancer 50:908-11. 2008
  3. ncbi VIP hypersecretion as primary or secondary syndrome in neuroblastoma: A retrospective study by the Société Française des Cancers de l'Enfant (SFCE)
    Franck Bourdeaut
    Institut Curie, Departement de Pediatrie, Paris, France
    Pediatr Blood Cancer 52:585-90. 2009
  4. ncbi [Rhadboid tumours: hSNF/INI1 deficient cancers of early childhood with aggressive behaviour]
    F Bourdeaut
    CHU de Nantes, Service d oncohématologie, 4 Quai Moncousu, 44000 Nantes Cedex, France
    Bull Cancer 97:37-45. 2010
  5. ncbi hSNF5/INI1-deficient tumours and rhabdoid tumours are convergent but not fully overlapping entities
    F Bourdeaut
    INSERM U509, Laboratoire de Pathologie Moléculaire des Cancers, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    J Pathol 211:323-30. 2007
  6. ncbi In neuroblastic tumours, Schwann cells do not harbour the genetic alterations of neuroblasts but may nevertheless share the same clonal origin
    F Bourdeaut
    INSERM, U830, Section de Recherche, Unité de Génétique et Biologie des Cancers, Institut Curie, Paris, France
    Oncogene 27:3066-71. 2008
  7. ncbi Germline mutations of the paired-like homeobox 2B (PHOX2B) gene in neuroblastoma
    Delphine Trochet
    Unite de Recherches sur les Handicaps Genetiques de l Enfant, INSERM U 393, and Département de Génétique, Hopital Necker Enfants Malades, Paris, France
    Am J Hum Genet 74:761-4. 2004
  8. ncbi Methylation-associated PHOX2B gene silencing is a rare event in human neuroblastoma
    Loic de Pontual
    Unité de Recherches sur les Handicaps Génétiques de l Enfant INSERM U 781, et Département de Génétique, Universite Rene Descartes, Faculte de Medecine, Hopitaux de Paris, Hopital Necker Enfants Malades, 149, rue de Sevres, 75743 Paris Cedex 15, France
    Eur J Cancer 43:2366-72. 2007
  9. ncbi Stepwise occurrence of a complex unbalanced translocation in neuroblastoma leading to insertion of a telomere sequence and late chromosome 17q gain
    Gudrun Schleiermacher
    , , Institut Curie, 26 rue d'Ulm, 75248 Paris Cedex 05, France
    Oncogene 24:3377-84. 2005

Collaborators

Detail Information

Publications9

  1. ncbi Germline mutations of the paired-like homeobox 2B (PHOX2B) gene in neuroblastoma
    Franck Bourdeaut
    Laboratoire de Pathologie Moléculaire des Cancers, INSERM U 509, Institut Curie, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    Cancer Lett 228:51-8. 2005
    ..These observations identify PHOX2B as the first predisposing gene to hereditary neuroblastic tumours...
  2. ncbi Alagille syndrome and nephroblastoma: Unusual coincidence of two rare disorders
    Franck Bourdeaut
    Institut Curie, Departement de Pediatrie, Paris F 75246, France
    Pediatr Blood Cancer 50:908-11. 2008
    ..In one nephroblastoma an additional somatic 1p36 deletion was present. The link between Alagille syndrome, JAG1 alterations and nephroblastoma is discussed...
  3. ncbi VIP hypersecretion as primary or secondary syndrome in neuroblastoma: A retrospective study by the Société Française des Cancers de l'Enfant (SFCE)
    Franck Bourdeaut
    Institut Curie, Departement de Pediatrie, Paris, France
    Pediatr Blood Cancer 52:585-90. 2009
    ..Neuroblastic tumors (NTs) are occasionally associated with watery diarrhea, due to Vasoactive Intestinal Peptide (VIP) secretion. Most reports are single cases and suggest a great homogeny within this sub-group of NTs...
  4. ncbi [Rhadboid tumours: hSNF/INI1 deficient cancers of early childhood with aggressive behaviour]
    F Bourdeaut
    CHU de Nantes, Service d oncohématologie, 4 Quai Moncousu, 44000 Nantes Cedex, France
    Bull Cancer 97:37-45. 2010
    ..Understanding the role of hSNF5/INI1 within the SWI-SNF complex for the epigenetic regulation of transcription might drive the future targeted therapies...
  5. ncbi hSNF5/INI1-deficient tumours and rhabdoid tumours are convergent but not fully overlapping entities
    F Bourdeaut
    INSERM U509, Laboratoire de Pathologie Moléculaire des Cancers, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    J Pathol 211:323-30. 2007
    ..The molecular investigation should be performed in infants when a rhabdoid predisposition syndrome is suspected...
  6. ncbi In neuroblastic tumours, Schwann cells do not harbour the genetic alterations of neuroblasts but may nevertheless share the same clonal origin
    F Bourdeaut
    INSERM, U830, Section de Recherche, Unité de Génétique et Biologie des Cancers, Institut Curie, Paris, France
    Oncogene 27:3066-71. 2008
    ..However, in tumours with both stroma-rich and -poor components, our results suggest that cells from both areas share a common progenitor...
  7. ncbi Germline mutations of the paired-like homeobox 2B (PHOX2B) gene in neuroblastoma
    Delphine Trochet
    Unite de Recherches sur les Handicaps Genetiques de l Enfant, INSERM U 393, and Département de Génétique, Hopital Necker Enfants Malades, Paris, France
    Am J Hum Genet 74:761-4. 2004
    ..Here, we report on germline mutations of PHOX2B in both a familial case of NB and a patient with the HSCR-NB association. PHOX2B, therefore, stands as the first gene for which germline mutations predispose to NB...
  8. ncbi Methylation-associated PHOX2B gene silencing is a rare event in human neuroblastoma
    Loic de Pontual
    Unité de Recherches sur les Handicaps Génétiques de l Enfant INSERM U 781, et Département de Génétique, Universite Rene Descartes, Faculte de Medecine, Hopitaux de Paris, Hopital Necker Enfants Malades, 149, rue de Sevres, 75743 Paris Cedex 15, France
    Eur J Cancer 43:2366-72. 2007
    ..9%). Altogether, both germinal and somatic anomalies at the PHOX2B locus are found in NB...
  9. ncbi Stepwise occurrence of a complex unbalanced translocation in neuroblastoma leading to insertion of a telomere sequence and late chromosome 17q gain
    Gudrun Schleiermacher
    , , Institut Curie, 26 rue d'Ulm, 75248 Paris Cedex 05, France
    Oncogene 24:3377-84. 2005
    ..Finally, screening of a panel of neuroblastoma cell lines identified interstitial telomeric sequences in three other cases, suggesting that this may be a recurrent mechanism leading to unbalanced translocations in neuroblastoma...