Research Topics
| Jean Philippe HaymannSummaryCountry: France Publications
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Detail Information
Publications
Glomerular hyperfiltration in adult sickle cell anemia: a frequent hemolysis associated featureJean Philippe Haymann
Universite Pierre et Marie Curie, Universite Paris 6, Institut National de la Santé et de la Recherche Médicale Unit 702, Physiology, Paris, France
Clin J Am Soc Nephrol 5:756-61. 2010..Glomerular damage is a common feature revealed by a microalbuminuria or a macroalbuminuria. Although glomerular hyperfiltration has been described for decades in this population, its prevalence in young adults is unknown...
Calpain activation and secretion promote glomerular injury in experimental glomerulonephritis: evidence from calpastatin-transgenic miceJulie Peltier
INSERM U702, 7Université Pierre et Marie Curie Paris6, UMRS702, Paris, France
J Am Soc Nephrol 17:3415-23. 2006..Thus, both activation and secretion of calpains participate in the development of immune glomerular injury...
Strong association between a new marker of hemolysis and glomerulopathy in sickle cell anemiaMicheline Maier-Redelsperger
Service d Hematologie Biologique, Hopital Tenon, Assistance Publique Hopitaux de Paris, F 75020, Paris, France
Blood Cells Mol Dis 45:289-92. 2010..Furthermore, by combining this parameter with LDH, we defined a composite variable, which we called CVar, that is highly correlated with albuminuria and might constitute a powerful new marker of risk for this complication...
Critical role of the calpain/calpastatin balance in acute allograft rejectionEmmanuel Letavernier
INSERM, UMR S 702, Paris, France
Eur J Immunol 41:473-84. 2011..This is the first study establishing that calpain inhibition delays allograft rejection by slowing down T-cell migration rather than proliferation...
Spectrum of mutations in Gitelman syndromeRosa Vargas-Poussou
Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Service de Genetique, Paris, France
J Am Soc Nephrol 22:693-703. 2011....
Determinants of osteopenia in male renal-stone-disease patients with idiopathic hypercalciuriaEmmanuel Letavernier
Service des explorations fonctionnelles multidisciplinaires, Hopital Tenon, 4 rue de la Chine, 75020 Paris, France
Clin J Am Soc Nephrol 6:1149-54. 2011..Although this pathologic link has been recognized for decades, the underlying mechanisms and risk factors associated with osteopenia/osteoporosis in this population remain partially understood...
Targeting the calpain/calpastatin system as a new strategy to prevent cardiovascular remodeling in angiotensin II-induced hypertensionEmmanuel Letavernier
Institut National de la Sante et de la Recherche Medicale, U702, Paris, France
Circ Res 102:720-8. 2008..These results indicate a critical role for calpains as downstream mediators in Ang II-induced cardiovascular remodeling and, thus, highlight an attractive therapeutic target...
Aggregated IgG bind to glomerular epithelial cells to stimulate urokinase release through an endocytosis-independent processJean Philippe Haymann
INSERM U 489, Université Paris 6 and Association Claude Bernard, Hopital Tenon, Paris, France
Nephron Exp Nephrol 98:e13-21. 2004..We therefore determined whether this binding could be responsible for a modification in the fibrinolytic activity of GEC...
Sirolimus interacts with pathways essential for podocyte integrityEmmanuel Letavernier
INSERM, U702 and Université Pierre et Marie Curie Paris 6, UMRS702, Paris, France
Nephrol Dial Transplant 24:630-8. 2009..Podocyte injury and focal segmental glomerulosclerosis have been related to sirolimus therapy in some patients but the pathways underlying these lesions remain hypothetical...
[Metabolic syndrome, obesity and urolithiasis]Olivier Traxer
Service d Urologie, Hopital Tenon, Paris, France
Prog Urol 16:418-20. 2006..The objective of this article is to review the metabolic syndrome in order to help urologists to recognize this syndrome so that they can identify patients requiring more specific management and medical follow-up...
