Research Topics
| Marc GregoireSummaryCountry: France Publications
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Detail Information
Publications
[Immunotherapy and malignant mesothelioma: clinical perspectives]Marc Gregoire
INSERM, Unite 601, Institut de Biologie, 9 quai Moncousu, 44093 Nantes Cedex
Bull Cancer 94:23-31. 2007..This article will review past and recent developments of such a clinical strategy...
What's the place of immunotherapy in malignant mesothelioma treatments?Marc Gregoire
INSERM, U892, Research Center in Oncology Nantes Angers, France
Cell Adh Migr 4:153-61. 2010..This article reviews past and recent developments of the clinical strategies that concern immunotherapy of mesothelioma...
Dendritic cell preparation for immunotherapeutic interventionsThomas Simon
INSERM U892, Institut de Biologie, 9 quai Moncousu, 44093 Nantes Cedex 01, France
Immunotherapy 1:289-302. 2009..Finally, we discuss the immunological and clinical outcomes in treated patients, with emphasis on the strategies that could be used to improve DC-based vaccination...
New perspectives in cancer virotherapy: bringing the immune system into playNicolas Boisgerault
INSERM, U892, CRCNA, IRTUN, Nantes, France
Immunotherapy 2:185-99. 2010..These findings offer an exciting outlook for the future of cancer virotherapy...
Opposite role of Bax and BCL-2 in the anti-tumoral responses of the immune systemGwenola Bougras
UMR 601 INSERM UN, Equipe 2, 9 quai Moncousu 44035 Nantes, France
BMC Cancer 4:54. 2004..The relative role of anti apoptotic (i.e. Bcl-2) or pro-apoptotic (e.g. Bax) proteins in tumor progression is still not completely understood...
Vaccination with epigenetically treated mesothelioma cells induces immunisation and blocks tumour growthFlora Guillot
INSERM, U892, Centre de Recherche en Cancérologie Nantes Angers, Institut de Recherche Therapeutique, Nantes, France
Vaccine 29:5534-43. 2011..Our data demonstrate that epigenetic drugs, such as SAHA, can stimulate tumour immunogenicity and improve the recognition of aggressive MM cells by the immune system in vivo...
Yin Yang of immunoregulation in organ transplantation and cancerYves Delneste
INSERM, U892, Centre de Recherche sur le Cancer Nantes Angers, F 49933 Angers, France
Immunotherapy 3:1-3. 2011....
Measles virus induces oncolysis of mesothelioma cells and allows dendritic cells to cross-prime tumor-specific CD8 responseAnne Gauvrit
INSERM, U601, Cancerology Research Department, Nantes, France
Cancer Res 68:4882-92. 2008..Altogether, these data strongly support the potential of oncolytic MV as an efficient therapeutic agent for mesothelioma cancer...
Efficient monocyte-derived dendritic cell generation in patients with acute myeloid leukemia after chemotherapy treatment: application to active immunotherapyPierre Joseph Royer
INSERM, U601, Nantes, France Université de NANTES, Faculte de Medecine, Centre de Recherche en Oncologie, Nantes, France
Exp Hematol 36:329-39. 2008..The aim of our study was to assess, for vaccine preparation, generation of monocyte-derived DCs in AML patients after CT...
A 5-aza-2'-deoxycytidine/valproate combination induces cytotoxic T-cell response against mesotheliomaS Leclercq
INSERM, U892, Institut de Recherche Therapeutique, Universite de Nantes, Nantes, France
Eur Respir J 38:1105-16. 2011..This property could be exploited in clinical investigations to develop MPM treatments combining chemotherapeutic and immunotherapeutic approaches...
Optimizing dendritic cell-based anticancer immunotherapy: maturation state does have clinical impactDorian McIlroy
INSERM U419, Institut de Biologie, 9 quai Moncousu, 44000 Nantes, France
Cancer Immunol Immunother 52:583-91. 2003..However, TNF-alpha is not the only molecule capable of inducing DC maturation, and strategies for improving clinical responses by optimizing DC maturation are discussed...
