Philippe A Grange

Summary

Country: France

Publications

  1. ncbi Nicotinamide inhibits Propionibacterium acnes-induced IL-8 production in keratinocytes through the NF-kappaB and MAPK pathways
    Philippe A Grange
    Hôpital Cochin Pavillon Gustave Roussy, Universite Paris Descartes, UPRES EA 1833, Laboratoire de Recherches en Dermatologie, 8, Rue Mechain, 75014 Paris, France
    J Dermatol Sci 56:106-12. 2009
  2. ncbi Does inflammatory acne result from imbalance in the keratinocyte innate immune response?
    Philippe A Grange
    Laboratoire de Recherche en Dermatologie, EA 1833, Faculte de Medecine, Universite Paris Descartes, 75679 Paris Cedex 14, France
    Microbes Infect 12:1085-90. 2010
  3. ncbi Production of superoxide anions by keratinocytes initiates P. acnes-induced inflammation of the skin
    Philippe A Grange
    Laboratoire de Recherche en Dermatologie, EA 1833, Faculte de Medecine, Universite Paris Descartes, Paris, France
    PLoS Pathog 5:e1000527. 2009

Detail Information

Publications3

  1. ncbi Nicotinamide inhibits Propionibacterium acnes-induced IL-8 production in keratinocytes through the NF-kappaB and MAPK pathways
    Philippe A Grange
    Hôpital Cochin Pavillon Gustave Roussy, Universite Paris Descartes, UPRES EA 1833, Laboratoire de Recherches en Dermatologie, 8, Rue Mechain, 75014 Paris, France
    J Dermatol Sci 56:106-12. 2009
    ..Nicotinamide has been shown to be an effective treatment for skin inflammation in various conditions, including acne vulgaris...
  2. ncbi Does inflammatory acne result from imbalance in the keratinocyte innate immune response?
    Philippe A Grange
    Laboratoire de Recherche en Dermatologie, EA 1833, Faculte de Medecine, Universite Paris Descartes, 75679 Paris Cedex 14, France
    Microbes Infect 12:1085-90. 2010
    ..acnes) strain. P. acnes stimulates the keratinocytes involved in the innate immune response, the intensity of which could be influenced either by bacterial intrinsic factors or by endogenous factors of the host...
  3. ncbi Production of superoxide anions by keratinocytes initiates P. acnes-induced inflammation of the skin
    Philippe A Grange
    Laboratoire de Recherche en Dermatologie, EA 1833, Faculte de Medecine, Universite Paris Descartes, Paris, France
    PLoS Pathog 5:e1000527. 2009
    ..Finally, retinoic acid derivates, the most efficient anti-acneic drugs, prevent O2(*-) production, IL-8 release and keratinocyte apoptosis, suggesting the relevance of this pathway in humans...