Olivia Fromigue

Summary

Country: France

Publications

  1. ncbi Crosstalks between integrin alpha 5 and IGF2/IGFBP2 signalling trigger human bone marrow-derived mesenchymal stromal osteogenic differentiation
    Zahia Hamidouche
    Laboratory of Osteoblast Biology and Pathology, INSERM U606, Paris F 75475, France
    BMC Cell Biol 11:44. 2010
  2. ncbi CYR61 downregulation reduces osteosarcoma cell invasion, migration, and metastasis
    Olivia Fromigue
    Laboratory of Osteoblast Biology and Pathology, INSERM, Paris, France
    J Bone Miner Res 26:1533-42. 2011
  3. ncbi Blockade of the RhoA-JNK-c-Jun-MMP2 cascade by atorvastatin reduces osteosarcoma cell invasion
    Olivia Fromigue
    INSERM U606, Lariboisiere Hospital, 75475 Paris Cedex 10, France
    J Biol Chem 283:30549-56. 2008
  4. ncbi Priming integrin alpha5 promotes human mesenchymal stromal cell osteoblast differentiation and osteogenesis
    Zahia Hamidouche
    Institut National de la Santé et de la Recherche Médicale U606, Hopital Lariboisiere, Paris, France
    Proc Natl Acad Sci U S A 106:18587-91. 2009
  5. ncbi Statin-induced inhibition of 3-hydroxy-3-methyl glutaryl coenzyme a reductase sensitizes human osteosarcoma cells to anticancer drugs
    Olivia Fromigue
    Institut National de la Santé et de la Recherche Médicale U606, Hopital Lariboisiere, 2 rue Ambroise Pare, 75475 Paris Cedex 10, France
    J Pharmacol Exp Ther 325:595-600. 2008
  6. ncbi Dual involvement of protein kinase C delta in apoptosis induced by syndecan-2 in osteoblasts
    Armelle Orosco
    Laboratory of Osteoblast Biology and Pathology, INSERM, Lariboisiere Hospital, University Paris 7, Paris, France
    J Cell Biochem 98:838-50. 2006
  7. ncbi Essential role of nuclear factor of activated T cells (NFAT)-mediated Wnt signaling in osteoblast differentiation induced by strontium ranelate
    Olivia Fromigue
    Laboratory of Osteoblast Biology and Pathology, INSERM U606, 75475 Paris Cedex 10, USA
    J Biol Chem 285:25251-8. 2010
  8. ncbi Autocrine fibroblast growth factor 18 mediates dexamethasone-induced osteogenic differentiation of murine mesenchymal stem cells
    Zahia Hamidouche
    INSERM U606, Hopital Lariboisiere, Paris, France
    J Cell Physiol 224:509-15. 2010
  9. ncbi FHL2 mediates dexamethasone-induced mesenchymal cell differentiation into osteoblasts by activating Wnt/beta-catenin signaling-dependent Runx2 expression
    Zahia Hamidouche
    INSERM U606, Hopital Lariboisiere, 2 rue Ambroise Pare, 75475 Paris Cedex 10, France
    FASEB J 22:3813-22. 2008
  10. ncbi Syndecan-2 overexpression induces osteosarcoma cell apoptosis: Implication of syndecan-2 cytoplasmic domain and JNK signaling
    Dominique Modrowski
    Laboratory of Osteoblast Biology and Pathology, Unité 606, INSERM, Lariboisiere Hospital, Universite Paris 7, 2 rue Ambroise Pare, 75475 Cedex 10 Paris, France
    Bone 37:180-9. 2005

Collaborators

Detail Information

Publications18

  1. ncbi Crosstalks between integrin alpha 5 and IGF2/IGFBP2 signalling trigger human bone marrow-derived mesenchymal stromal osteogenic differentiation
    Zahia Hamidouche
    Laboratory of Osteoblast Biology and Pathology, INSERM U606, Paris F 75475, France
    BMC Cell Biol 11:44. 2010
    ..In this study, we used microarray analysis to identify signalling molecules that promote osteogenic differentiation in human bone marrow stroma derived MSCs...
  2. ncbi CYR61 downregulation reduces osteosarcoma cell invasion, migration, and metastasis
    Olivia Fromigue
    Laboratory of Osteoblast Biology and Pathology, INSERM, Paris, France
    J Bone Miner Res 26:1533-42. 2011
    ..These data provide a novel molecular target for therapeutic intervention in metastatic osteosarcoma...
  3. ncbi Blockade of the RhoA-JNK-c-Jun-MMP2 cascade by atorvastatin reduces osteosarcoma cell invasion
    Olivia Fromigue
    INSERM U606, Lariboisiere Hospital, 75475 Paris Cedex 10, France
    J Biol Chem 283:30549-56. 2008
    ..This suggests a novel strategy targeting RhoA-JNK-c-Jun signaling to reduce osteosarcoma cell tumorigenesis...
  4. ncbi Priming integrin alpha5 promotes human mesenchymal stromal cell osteoblast differentiation and osteogenesis
    Zahia Hamidouche
    Institut National de la Santé et de la Recherche Médicale U606, Hopital Lariboisiere, Paris, France
    Proc Natl Acad Sci U S A 106:18587-91. 2009
    ..This may be used for tissue regeneration in bone disorders where the recruitment or capacity of hMSCs is compromised...
  5. ncbi Statin-induced inhibition of 3-hydroxy-3-methyl glutaryl coenzyme a reductase sensitizes human osteosarcoma cells to anticancer drugs
    Olivia Fromigue
    Institut National de la Santé et de la Recherche Médicale U606, Hopital Lariboisiere, 2 rue Ambroise Pare, 75475 Paris Cedex 10, France
    J Pharmacol Exp Ther 325:595-600. 2008
    ....
  6. ncbi Dual involvement of protein kinase C delta in apoptosis induced by syndecan-2 in osteoblasts
    Armelle Orosco
    Laboratory of Osteoblast Biology and Pathology, INSERM, Lariboisiere Hospital, University Paris 7, Paris, France
    J Cell Biochem 98:838-50. 2006
    ..This establishes a functional interaction between SYND2 and PKCdelta in osteoblasts...
  7. ncbi Essential role of nuclear factor of activated T cells (NFAT)-mediated Wnt signaling in osteoblast differentiation induced by strontium ranelate
    Olivia Fromigue
    Laboratory of Osteoblast Biology and Pathology, INSERM U606, 75475 Paris Cedex 10, USA
    J Biol Chem 285:25251-8. 2010
    ....
  8. ncbi Autocrine fibroblast growth factor 18 mediates dexamethasone-induced osteogenic differentiation of murine mesenchymal stem cells
    Zahia Hamidouche
    INSERM U606, Hopital Lariboisiere, Paris, France
    J Cell Physiol 224:509-15. 2010
    ....
  9. ncbi FHL2 mediates dexamethasone-induced mesenchymal cell differentiation into osteoblasts by activating Wnt/beta-catenin signaling-dependent Runx2 expression
    Zahia Hamidouche
    INSERM U606, Hopital Lariboisiere, 2 rue Ambroise Pare, 75475 Paris Cedex 10, France
    FASEB J 22:3813-22. 2008
    ....
  10. ncbi Syndecan-2 overexpression induces osteosarcoma cell apoptosis: Implication of syndecan-2 cytoplasmic domain and JNK signaling
    Dominique Modrowski
    Laboratory of Osteoblast Biology and Pathology, Unité 606, INSERM, Lariboisiere Hospital, Universite Paris 7, 2 rue Ambroise Pare, 75475 Cedex 10 Paris, France
    Bone 37:180-9. 2005
    ..This supports a role for syndecan-2 in the regulation of osteosarcoma cell fate and identifies one signaling pathway by which syndecan-2 induces apoptosis in osteosarcoma cells...
  11. ncbi Distinct osteoblastic differentiation potential of murine fetal liver and bone marrow stroma-derived mesenchymal stem cells
    Olivia Fromigue
    INSERM U606, Universite Paris 7, Hopital Lariboisiere, Paris, France
    J Cell Biochem 104:620-8. 2008
    ....
  12. ncbi Syndecan-2 affects the basal and chemotherapy-induced apoptosis in osteosarcoma
    Armelle Orosco
    INSERM U606 and Université Paris 7, Hopital Lariboisiere, 2 rue Ambroise Pare, 75475 Paris Cedex 10, France
    Cancer Res 67:3708-15. 2007
    ..Moreover, our data identify syndecan-2 as a new factor mediating the antioncogenic effect of chemotherapeutic drugs...
  13. ncbi Calcium sensing receptor-dependent and receptor-independent activation of osteoblast replication and survival by strontium ranelate
    Olivia Fromigue
    Laboratory of Osteoblast Biology and Pathology, INSERM U606 and University Paris 7, Paris, France
    J Cell Mol Med 13:2189-99. 2009
    ..The finding that CaSR-dependent and CaSR-independent pathways mediate the beneficial effects of strontium ranelate on osteoblasts, provides novel insight into the mechanism of action of this anti-osteoporotic agent on osteoblastogenesis...
  14. ncbi Characterization of distinct mesenchymal-like cell populations from human skeletal muscle in situ and in vitro
    Séverine Lecourt
    UPMC AIM UMR S 974, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Exp Cell Res 316:2513-26. 2010
    ..These results underline the diversity of human muscle cells, and the shared or restricted commitment abilities of the main lineages under defined conditions...
  15. ncbi Osteogenic differentiation of human marrow-derived mesenchymal stem cells
    Pierre J Marie
    Laboratory of Osteoblast Biology and Pathology Unité 606 INSERM, Hopital Lariboisiere, 2 rue Ambroise Pare, 75475 Paris Cedex 10, France
    Regen Med 1:539-48. 2006
    ..In the future this may lead to selective therapeutic strategies for tissue engineering application in bone regeneration and repair in humans...
  16. ncbi Apoptosis in membranous bone formation: role of fibroblast growth factor and bone morphogenetic protein signaling
    Olivia Fromigue
    Laboratory of Osteoblast Biology and Pathology, INSERM Unite 606, Hopital Lariboisiere, 2 rue Ambroise Pare, 75475 Paris Cedex 10, France
    Crit Rev Eukaryot Gene Expr 15:75-92. 2005
    ..These mechanisms allow a fine control of the number of functional bone-forming cells and, thereby, the normal progression of membranous bone formation...
  17. ncbi Bone morphogenetic protein receptor IB signaling mediates apoptosis independently of differentiation in osteoblastic cells
    Eric Hay
    Laboratory of Osteoblast Biology and Pathology, INSERM U 349, CNRS, Lariboisiere Hospital, 75475 Cedex 10 Paris, France
    J Biol Chem 279:1650-8. 2004
    ....