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Species | Patrice DunoyerSummaryCountry: France Publications
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Publications
Intracellular localization of the peanut clump virus replication complex in tobacco BY-2 protoplasts containing green fluorescent protein-labeled endoplasmic reticulum or Golgi apparatusPatrice Dunoyer
, Centre National de la Recherche Scientifique, 67084 Strasbourg Cedex, France
J Virol 76:865-74. 2002..The concomitant extensive rearrangement of these membranous structures leads to the formation of intracellular compartments in which synthesis and accumulation of the viral RNA occur in defined areas...- Molecular basis for mitochondrial localization of viral particles during beet necrotic yellow vein virus infectionClarisse Valentin
, Strasbourg, France
J Virol 79:9991-10002. 2005..Further data show that virions are subsequently released from mitochondria and accumulate in the cytosol... - An endogenous, systemic RNAi pathway in plantsPatrice Dunoyer
Institut de Biologie Moleculaire des Plantes du CNRS, UPR2357, Universite de Strasbourg, Strasbourg Cedex, France
EMBO J 29:1699-712. 2010..Collectively, these results define the existence of a bona fide, endogenous and systemic RNAi pathway in plants that may have implications in adaptation, epiallelism and trans-generational memory... - [The battle of Silence : action and inhibition of RNA silencing during plant/virus interactions]Patrice Dunoyer
Institut de Biologie Moleculaire des Plantes du CNRS, IBMP CNRS, Universite de Strasbourg, France
Med Sci (Paris) 25:505-11. 2009..Here we review the mechanism of RNA silencing and its inhibition during plant/virus interactions and suggest the possible consequences of this molecular arms race on the evolution of both viral and host genomes... - Mixing and matching: the essence of plant systemic silencing?Patrice Dunoyer
Institut de Biologie Moleculaire des Plantes, CNRS UPR2357 Université Louis Pasteur, Strasbourg Cedex, France
Trends Genet 24:151-4. 2008..In a recent study carried out in Arabidopsis thaliana, interesting clues were provided that suggest mechanisms by which systemic RNA silencing signals might be produced and perceived between distant plant organs... - Small RNA duplexes function as mobile silencing signals between plant cellsPatrice Dunoyer
Institut de Biologie Moleculaire des Plantes du CNRS, Université de Strasbourg 12 rue du Général Zimmer, 67084 Strasbourg Cedex, France
Science 328:912-6. 2010..Cell-to-cell movement is unlikely to involve AGO1-bound siRNA single strands, but instead likely involves siRNA duplexes... - A cellular microRNA mediates antiviral defense in human cellsCharles Henri Lecellier
CNRS Unité Propre de Recherche UPR 2357, Institut de Biologie Moleculaire des Plantes, 12 rue du Général Zimmer, 67084 Strasbourg Cedex, France
Science 308:557-60. 2005..Therefore, through fortuitous recognition of foreign nucleic acids, cellular microRNAs have direct antiviral effects in addition to their regulatory functions... - In vivo investigation of the transcription, processing, endonucleolytic activity, and functional relevance of the spatial distribution of a plant miRNAEneida Abreu Parizotto
, 67084 Strasbourg Cedex, France
Genes Dev 18:2237-42. 2004..Work in sde1 background revealed a near-perfect spatial overlap between the patterns of miR171 transcription and activity, supporting the idea that plant miRNAs enable cell differentiation... - Widespread translational inhibition by plant miRNAs and siRNAsPeter Brodersen
Institut de Biologie Moleculaire des Plantes du CNRS, Unité Propre de Recherche 2357, 12 rue du Général Zimmer, 67084 Strasbourg Cedex, France
Science 320:1185-90. 2008..Also as in animals, the decapping component VARICOSE (VCS)/Ge-1 is required for translational repression by miRNAs, which suggests that the underlying mechanisms in the two kingdoms are related... - Probing the microRNA and small interfering RNA pathways with virus-encoded suppressors of RNA silencingPatrice Dunoyer
, 67084 Strasbourg Cedex, France
Plant Cell 16:1235-50. 2004..Therefore, silencing suppressors are valuable probes of the complexity of RNA silencing... - Intra- and intercellular RNA interference in Arabidopsis thaliana requires components of the microRNA and heterochromatic silencing pathwaysPatrice Dunoyer
Institut de Biologie Moleculaire des Plantes, Centre National de la Recherche Scientifique CNRS UPR2357, 12 rue du Général Zimmer, 67084 Strasbourg Cedex, France
Nat Genet 39:848-56. 2007..Finally, we show that the genetics of RNAi is distinct from that of antiviral silencing and propose that this experimental silencing pathway has a direct endogenous plant counterpart... - Mapping of viral RNA sequences required for assembly of peanut clump virus particlesOdile Hemmer
Institut de Biologie Moléculaire des Plantes du CNRS et de l Université Louis Pasteur, 12 rue du Général Zimmer, 67084 Strasbourg Cedex, France
J Gen Virol 84:2585-94. 2003..One was in the 5'-proximal coat protein gene and the other in the P14 gene near the RNA 3' terminus. There were no obvious sequence homologies between the different assembly initiation sequences... - DICER-LIKE 4 is required for RNA interference and produces the 21-nucleotide small interfering RNA component of the plant cell-to-cell silencing signalPatrice Dunoyer
Institut de Biologie Moléculaire des Plantes du CNRS UPR 2357, 12, rue du Général Zimmer, 67084 Strasbourg Cedex, France
Nat Genet 37:1356-60. 2005.... - Transitivity-dependent and -independent cell-to-cell movement of RNA silencingChristophe Himber
, , 67084 Strasbourg, France
EMBO J 22:4523-33. 2003..The likely nature of the nucleic acids involved is presented... - The complex interplay between plant viruses and host RNA-silencing pathwaysPatrice Dunoyer
, CNRS UPR2357, Strasbourg, France
Curr Opin Plant Biol 8:415-23. 2005..This complex interplay has implications in the context of disease resistance and evolution of viral genomes... - Induction, suppression and requirement of RNA silencing pathways in virulent Agrobacterium tumefaciens infectionsPatrice Dunoyer
CNRS UPR2357, IBMP, Strasbourg, France
Nat Genet 38:258-63. 2006..The similarities and specificities of the A. tumefaciens RNA silencing interaction are discussed and contrasted with the situation encountered with plant viruses... - Identification, subcellular localization and some properties of a cysteine-rich suppressor of gene silencing encoded by peanut clump virusPatrice Dunoyer
Institut de Biologie Moléculaire des Plantes du CNRS et de l Université Louis Pasteur, 12 rue du Général Zimmer, 67084 Strasbourg, France
Plant J 29:555-67. 2002..The coiled-coil sequence is necessary for the anti-PTGS activity of P15, but the peroxisomal localization signal is not, although it is required for efficient intercellular movement of the virus...