Research Topics
Species | Maxime DougadosSummaryCountry: France Publications
| Collaborators
|
Detail Information
Publications
Smokers in early axial spondyloarthritis have earlier disease onset, more disease activity, inflammation and damage, and poorer function and health-related quality of life: results from the DESIR cohortHo Yin Chung
Correspondence to Professor Maxime Dougados, Rheumatology B Department, Cochin Hospital, Paris 75014, France
Ann Rheum Dis 71:809-16. 2012..To investigate the association of smoking with various clinical, functional and imaging outcomes in patients with early axial spondyloarthritis (SpA)...
Onset of action of etanercept in rheumatoid arthritis based on patient-reported outcomesMaxime Dougados
Paris Descartes University UPRES EA 4058 APHP, Cochin Hospital, Rheumatology B Dpt, 75014 Paris, France
Clin Exp Rheumatol 30:266-8. 2012..The efficacy of TNF blockers is usually evaluated after 2 to 4 weeks of therapy. EULAR-RAID is a valid patient-reported outcome composite index...
Profile and course of early rheumatoid arthritis in Morocco: a two-year follow-up studyKarima Benbouazza
Rheumatology Department, Mohamed Vth University Souissi, Rabat, Morocco
BMC Musculoskelet Disord 12:266. 2011..This study aimed to establish the profile and the evolution of an early Rheumatoid arthritis (RA) cohort in the Moroccan population and also to search possible predictor factors of structural progression...
Status versus changes, onset of action, and sustainability--how do we define and present these concepts in clinical trial reports in rheumatology?Maxime Dougados
Rheumatology B Department, Hopital Cochin, 27 rue du Faubourg Saint Jacques, Paris, France
Bull NYU Hosp Jt Dis 69:111-5. 2011....
ASAS recommendations for collecting, analysing and reporting NSAID intake in clinical trials/epidemiological studies in axial spondyloarthritisMaxime Dougados
Rheumatology B Department, Paris Descartes University, Cochin Hospital, Paris 75014, France
Ann Rheum Dis 70:249-51. 2011..This initiative should facilitate the conduct and analysis of clinical studies/trials...
Evaluation of several ultrasonography scoring systems for synovitis and comparison to clinical examination: results from a prospective multicentre study of rheumatoid arthritisMaxime Dougados
Medicine Faculty, Rheumatology B Department, Descartes University UPRES EA 4058 APHP, Cochin Hospital, 27 rue du Faubourg Saint Jacques, 75014 Paris, France
Ann Rheum Dis 69:828-33. 2010..To evaluate different global ultrasonographic (US) synovitis scoring systems as potential outcome measures of rheumatoid arthritis (RA) according to the Outcome Measures in Rheumatoid Arthritis Clinical Trials (OMERACT) filter...
Symptomatic slow-acting drugs for osteoarthritis: what are the facts?Maxime Dougados
Rheumatology Department, Cochin Teaching Hospital, School of Medicine, Paris Descartes University, Assistance Publique Hopitaux de Paris, 27, rue du Faubourg Saint Jacques, 75014 Paris, France
Joint Bone Spine 73:606-9. 2006..In addition, the characteristics of the patients who are most likely to benefit from SySADOA need to be identified...
SpondyloarthritisMaxime Dougados
Paris Descartes University, Medicine Faculty, UPRES EA 4058, AP HP, Cochin Hospital, Department of Rheumatology B, Paris, France
Lancet 377:2127-37. 2011....
Blood memory B cells are disturbed and predict the response to rituximab in patients with rheumatoid arthritisJeremie Sellam
Hopital Bicetre, AP HP, INSERM U1012, and Université Paris Sud 11, Le Kremlin Bicetre, France
Arthritis Rheum 63:3692-701. 2011..To examine blood B cell subsets in patients with rheumatoid arthritis (RA) prior to B cell depletion therapy and to assess their potential as predictors of clinical response to rituximab (RTX)...
Structural evaluation in the management of patients with rheumatoid arthritis: development of recommendations for clinical practice based on published evidence and expert opinionLaure Gossec
Rheumatology Department, Cochin Teaching Hospital, Paris, France
Joint Bone Spine 72:229-34. 2005..They should help to improve practice uniformity and, ultimately, to improve the management of RA...
Nonpharmacological treatments in early rheumatoid arthritis: clinical practice guidelines based on published evidence and expert opinionLaure Gossec
Service de Rhumatologie B, CHU de Cochin, 27, rue du Faubourg Saint-Jacques, 75014 Paris, France
Joint Bone Spine 73:396-402. 2006..CONCLUSION: These recommendations should help to improve practice uniformity and, ultimately, to improve the management of RA...
A randomised, multicentre, double-blind, placebo-controlled trial of etanercept in adults with refractory heel enthesitis in spondyloarthritis: the HEEL trialMaxime Dougados
Paris Descartes University, and APHP, Rheumatology B Department, Cochin Hospital, Paris, France
Ann Rheum Dis 69:1430-5. 2010..The objective of this study was to investigate the efficacy of etanercept in refractory heel enthesitis related to SpA...
Methotrexate therapy for rheumatoid arthritis: clinical practice guidelines based on published evidence and expert opinionStephan Pavy
Service de Rhumatologie A, CHU Cochin, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France
Joint Bone Spine 73:388-95. 2006..CONCLUSION: Recommendations about methotrexate therapy for RA were developed. These recommendations should help to improve practice uniformity and, ultimately, to improve the management of RA...
The influence of the definition of patient global assessment in assessment of disease activity according to the Disease Activity Score (DAS28) in rheumatoid arthritisMaxime Dougados
Department of Rheumatology B, Cochin Hospital, Paris Pfizer SAS France, Paris France
J Rheumatol 38:2326-8. 2011..We studied the influence of the use of 3 different techniques of PGA on the assessment of disease activity...
Maintenance of infliximab treatment in ankylosing spondylitis: results of a one-year randomized controlled trial comparing systematic versus on-demand treatmentMaxime Breban
Hopital Ambroise Pare, Assistance Publique Hopitaux de Paris, Boulogne Billancourt, France
Arthritis Rheum 58:88-97. 2008..This study was undertaken to compare the efficacy of continuous treatment with infliximab with that of a treatment regimen adapted to symptom recurrence. Methotrexate (MTX) in combination with infliximab was also tested...
Self-reported prevalence of psoriasis and evaluation of the impact on the natural history of hip osteoarthritis: results of a 10 years follow-up study of 507 patients (ECHODIAH study)Umut Kalyoncu
Paris Descartes University, Medicine Faculty, UPRES EA 4058, APHP, Rheumatology B Department, Cochin Hospital, Paris, France
Joint Bone Spine 76:389-93. 2009..The objective of the present study was to assess the frequency of self-reported psoriasis in a hip osteoarthritis (OA) cohort, and a secondary objective was to assess the course of hip OA with psoriasis...
Retention rates of tumor necrosis factor blockers in daily practice in 770 rheumatic patientsMuriel Duclos
Rene Descartes University, Faculty of Medicine, Paris, France
J Rheumatol 33:2433-8. 2006..Moreover, results suggest greater benefit in SpA. The role of concomitant DMARD remains to be confirmed...
Prognostic factors of 10-year radiographic outcome in early rheumatoid arthritis: a prospective studyNatacha Courvoisier
Service de Rhumatologie, Hopital Saint Antoine, 184 rue du Faubourg Saint Antoine, Paris, 75012, France
Arthritis Res Ther 10:R106. 2008..The objectives of this study were to determine the predictive factors of long-term radiographic outcome of rheumatoid arthritis (RA) and to describe the relationship between joint damage and disability over the course of the disease...
OARSI/OMERACT criteria of being considered a candidate for total joint replacement in knee/hip osteoarthritis as an endpoint in clinical trials evaluating potential disease modifying osteoarthritic drugsMaxime Dougados
Paris Descartes University, Medicine Faculty, UPRES EA 4058, AP HP, Cochin Hospital, Rheumatology B Department, Paris, France
J Rheumatol 36:2097-9. 2009..We propose a composite index including structural and symptomatic variables of osteoarthritis (OA) as criteria for being considered a candidate for total joint replacement as an endpoint in clinical trials evaluating potential DMOAD...
Prospective assessment of body weight, body composition, and bone density changes in patients with spondyloarthropathy receiving anti-tumor necrosis factor-alpha treatmentKarine Briot
Paris Descartes University, Medicine Faculty, Cochin Hospital, Paris, France
J Rheumatol 35:855-61. 2008..To determine the changes in body weight, body composition, and bone density in patients with spondyloarthropathy (SpA) receiving anti-tumor necrosis factor-alpha (TNF-alpha) treatment...
Rituximab therapy in rheumatoid arthritis in daily practiceNoémie Assous
Department of Rheumatology A and Rheumatology B, Paris Descartes University, Medical Faculty, Cochin Hospital, AP HP, Paris, France
J Rheumatol 35:31-4. 2008..Our aim was to assess in routine care the effects of rituximab in patients with RA who had experienced an inadequate response to anti-tumor necrosis factor-alpha (TNF-alpha) agents or had a contraindication to these drugs...
Hormonal replacement therapy may reduce the risk for RA in women with early arthritis who carry HLA-DRB1 *01 and/or *04 alleles by protecting against the production of anti-CCP: results from the ESPOIR cohortCarine Salliot
Paris Descartes University, Medicine Faculty UPRES EA 4058 APHP, Hopital Cochin, Service de Rhumatologie B, rue du Faubourg Saint Jacques, Paris, France
Ann Rheum Dis 69:1683-6. 2010....
Feeling good rather than feeling better matters more to patientsFlorence Tubach
Assistance Publique Hopitaux de Paris, Hopital Bichat, INSERM U738, Universite Paris 7 Denis Diderot, Paris, France
Arthritis Rheum 55:526-30. 2006....
Prevalence and clinical characteristics of dactylitis in spondylarthritis: a descriptive analysis of 275 patientsJudith Payet
Paris Descartes University, Medicine Faculty, APHP, Rheumatology B Department, Cochin Hospital, Paris, France
Clin Exp Rheumatol 30:191-6. 2012..Our objective was to assess the prevalence of dactylitis among a cohort of patients with spondylarthritis in a tertiary care centre and to describe the clinical characteristics of dactylitis...
Performance of the assessment in spondyloarthritis international society classification for axial and peripheral spondyloarthritis in an established clinical cohort: comparison with criteria sets of amor and the European spondylarthropathy study groupPeter P Cheung
Rheumatology B Department, Hopital Cochin, 27 rue du Faubourg Saint Jacques, 75014, Paris, France
J Rheumatol 39:816-21. 2012..To evaluate the performance of the Assessment in Spondyloarthritis International Society (ASAS) criteria (axial or peripheral) against the Amor and European Spondylarthropathy Study Group criteria in established spondyloarthritis (SpA)...
Serial determination of cyclic citrullinated peptide autoantibodies predicted five-year radiological outcomes in a prospective cohort of patients with early rheumatoid arthritisOlivier Meyer
Rheumatology Unit, Assistance Publique Hopitaux de Paris, Bichat University Hospital, 75018 Paris, France
Arthritis Res Ther 8:R40. 2006..In conclusion, serially determined anti-CCP2 antibodies during the first three years of follow-up performs better than baseline determination for predicting radiographic progression in patients with early RA...
Influence of patient education on exercise compliance in rheumatoid arthritis: a prospective 12-month randomized controlled trialAnne Mayoux-Benhamou
Department of Rehabilitation, Cochin Hospital, 27 rue du Faubourg Saint Jacques, 75679 Paris Cedex 14, France
J Rheumatol 35:216-23. 2008..To determine the effect of education on the exercise habits of patients with rheumatoid arthritis (RA) after 6 and 12 months...
Stability of the patient acceptable symptomatic state over time in outcome criteria in ankylosing spondylitisFlorence Tubach
Assistance Publique Hopitaux de Paris, Bichat Hospital, University Paris VII, INSERM U738, Paris, France
Arthritis Rheum 55:960-3. 2006..Our goal was to determine the PASS in main outcome criteria when assessing patients with ankylosing spondylitis (AS) and to evaluate whether the PASS is stable over time...
Reliability of patient self-evaluation of swollen and tender joints in rheumatoid arthritis: A comparison study with ultrasonography, physician, and nurse assessmentsPeter P Cheung
Paris Descartes University, UPRES EA, Cochin Hospital, France
Arthritis Care Res (Hoboken) 62:1112-9. 2010....
B cell activation biomarkers as predictive factors for the response to rituximab in rheumatoid arthritis: A six-month, national, multicenter, open-label studyJeremie Sellam
Hopital Bicetre, Assistance Publique Hopitaux de Paris, INSERM U1012, and Université Paris Sud 11, Le Kremlin Bicetre, France
Arthritis Rheum 63:933-8. 2011..To examine whether serum B cell markers can predict response to rituximab, a B cell-depleting monoclonal antibody, in patients with refractory rheumatoid arthritis (RA)...
PTPN22 R620W genotype-phenotype correlation analysis and gene-environment interaction study in early rheumatoid arthritis: results from the ESPOIR cohortCarine Salliot
Rheumatology B Department, Cochin Hospital, Paris Descartes University, Medicine Faculty UPRES EA 4058 APHP, France
Rheumatology (Oxford) 50:1802-8. 2011..To investigate genotype-phenotype correlation and gene-environment interaction between PTPN22 R620W environmental factors such as tobacco/hormonal treatments in an inception cohort of RA patients...
OARSI/OMERACT initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis. An OMERACT 10 Special Interest GroupLaure Gossec
Paris Descartes University, Medicine Faculty, Paris, France
J Rheumatol 38:1765-9. 2011....
The DESIR cohort: A 10-year follow-up of early inflammatory back pain in France: Study design and baseline characteristics of the 708 recruited patientsMaxime Dougados
Paris Descartes University, Medicine Faculty, UPRES EA 4058, AP HP, Cochin Hospital, Rheumatology B Department, Paris 14, France
Joint Bone Spine 78:598-603. 2011....
Clinical relevance of C-reactive protein in ankylosing spondylitis and evaluation of the NSAIDs/coxibs' treatment effect on C-reactive proteinMathilde Benhamou
Rheumatology Department, Pitie Salpetriere Hospital, Paris VI University, France
Rheumatology (Oxford) 49:536-41. 2010..To evaluate the clinical relevance of CRP in AS and investigate the treatment effect of NSAIDs/coxibs on CRP...
Validation of a short form of the Western Ontario and McMaster Universities Osteoarthritis Index function subscale in hip and knee osteoarthritisGabriel Baron
AP HP, Hopital Bichat, Département d Eidémiologie, Biostatistique et Recherche Clinique, INSERM, U738, Paris, France
Arthritis Rheum 57:633-8. 2007..The goal of the present study was to validate this short form...
Reproducibility and sensitivity to change of four scoring methods for the radiological assessment of osteoarthritis of the handEmmanuel Maheu
Rheumatology Department, Hopital Saint Antoine, and Université Diderot, Paris VII, France
Ann Rheum Dis 66:464-9. 2007..Osteoarthritis (OA) of the hand could be a relevant model to study the progression of OA in structure-modification trials. Various methods are proposed to assess hand OA and its progression radiologically...
Impact of ultrasound imaging on local corticosteroid injections of symptomatic ankle, hind-, and mid-foot in chronic inflammatory diseasesXavier Ayral
Cochin Hospital, , Paris, France
Arthritis Rheum 53:284-92. 2005..0170). CONCLUSION: US frequently led the physician to change his diagnosis of inflammatory lesions in painful foot, and consequently his planning of CS injections. Moreover, US could improve the response to local treatment...
Minimal clinically important improvement and patient acceptable symptom state for subjective outcome measures in rheumatic disordersFlorence Tubach
Département d Epidémiologie, Biostatistique et Recherche Clinique, Hopital Bichat, Paris, France
J Rheumatol 34:1188-93. 2007..The purpose of this SIG at OMERACT 8 was to inform participants of the MCII and PASS concepts and to agree on MCII and PASS values for pain, patient global assessment, and functional impairment...
C-reactive protein predicts tumor necrosis factor-alpha blocker retention rate in axial ankylosing spondylitisMathieu Luc
Department of Rheumatology B, Paris 5 Medicine Faculty, Cochin Hospital, APHP, Paris, France
J Rheumatol 34:2078-81. 2007..We assessed the retention rate of TNF blockers in patients with axial AS, according to baseline CRP and other potentially predictive measures...
Role and modalities of information and education in the management of patients with rheumatoid arthritis: development of recommendations for clinical practice based on published evidence and expert opinionBruno Fautrel
Service de Rhumatologie, , Paris, France
Joint Bone Spine 72:163-70. 2005..7% to 100%. CONCLUSION: Recommendations about educating and informing patients with RA in everyday practice were developed. They should increase practice uniformity and ultimately optimize the management of patients with RA...
Influence of the experience of the reader on reliability of joint space width measurement. A cross-sectional multiple reading study in hip osteoarthritisPaul Ornetti
Department of Rheumatology, Dijon University Hospital, Medicine Faculty, Burgundy University, 3, rue du Faubourg Raines, 21000 Dijon, France
Joint Bone Spine 78:499-505. 2011..The objectives were to evaluate improvement in reliability of joint space width (JSW) measurements, according to the previous experience of the readers in hip osteoarthritis (OA)...
Risk of infections in bronchiectasis during disease-modifying treatment and biologics for rheumatic diseasesGuillaume Geri
Paris Descartes University, Medicine Faculty, Assistance Publique Hopitaux de Paris, Rheumatology B Department, Cochin Hospital, Paris France
BMC Infect Dis 11:304. 2011..Data are lacking on the risk of lower respiratory tract infections in patients treated with biologic agents...
Usefulness of routine electrocardiography for heart disease screening in patients with spondyloarthropathy or rheumatoid arthritisTiphaine Miquel Goulenok
Services de Rhumatologie A, Hopital Cochin, AP HP, Universite Paris Descartes, 27, rue du faubourg 75679 Paris cedex 14, France
Joint Bone Spine 77:146-50. 2010..To assess the usefulness of routine electrocardiography for heart disease screening in patients with spondyloarthropathy (SpA) or rheumatoid arthritis (RA)...
Effects of etanercept on serum biochemical markers of cartilage metabolism in patients with spondyloarthropathyKarine Briot
Faculte de Medecine, Universite Paris Descartes, UPRES EA 4058, Hopital Cochin, Paris, France
J Rheumatol 35:310-4. 2008..We describe the effects of etanercept on biochemical markers of type II collagen synthesis and degradation in patients with SpA followed for 2 years...
Evaluation of the patient acceptable symptom state as an outcome measure in patients with ankylosing spondylitis: data from a randomized controlled trialMaxime Dougados
Hôpital Cochin and University of Paris, Paris, France
Arthritis Rheum 59:553-60. 2008..To evaluate the feasibility/acceptability, reliability, external validity, and discriminant capacity of the Patient Acceptable Symptom State (PASS) concept in patients with active ankylosing spondylitis (AS)...
Circulating concentration of infliximab and response to treatment in ankylosing spondylitis: results from a randomized control studyRoman Krzysiek
Inserm Unité 764, Universite Paris Sud 11, and Hôpital Antoine Béclère, Assistance Publique Hopitaux de Paris, Clamart, France
Arthritis Rheum 61:569-76. 2009..This study compared the circulating infliximab concentration and the presence of clinical symptoms in patients continuously treated with infliximab or after treatment interruption...
Evaluation of the patient acceptable symptom state in a pooled analysis of two multicentre, randomised, double-blind, placebo-controlled studies evaluating lumiracoxib and celecoxib in patients with osteoarthritisMaxime Dougados
Department of Rheumatology, Hopital Cochin, 27 rue du Faubourg Saint Jacques, 75014 Paris, France
Arthritis Res Ther 9:R11. 2007..Trial registration numbers: NCT00366938 and NCT00367315...
Risk factors for total joint arthroplasty infection in patients receiving tumor necrosis factor ?-blockers: a case-control studyMelanie Gilson
Rheumatology B Department, Cochin Hospital, Paris 75014, France
Arthritis Res Ther 12:R145. 2010....
Osteoarticular involvement in a series of 100 patients with sarcoidosis referred to rheumatology departmentsNatacha Thelier
Department of Rheumatology A, Paris Descartes University, Paris, France
J Rheumatol 35:1622-8. 2008..To analyze the pattern of osteoarticular lesions in patients with sarcoidosis hospitalized in 4 rheumatology departments...
Intraarticular glucocorticoid injections in rapidly destructive hip osteoarthritisCaroline Villoutreix
Rheumatology B Department, Cochin Teaching Hospital, Assistance Publique des Hopitaux de Paris, René Descartes Paris V University, France
Joint Bone Spine 73:66-71. 2006....
Pigmented villonodular synovitis: a retrospective single-center study of 122 cases and review of the literatureSebastien Ottaviani
Paris Descartes University, Medicine Faculty, APHP, Rheumatology B Department, Cochin Hospital, France
Semin Arthritis Rheum 40:539-46. 2011..Pigmented villonodular synovitis (PVNS) is a rare but disabling disease. The objective was to describe the clinical presentation and outcomes of PVNS according to its localization...
Switching between tumour necrosis factor blockers in spondyloarthritis: a retrospective monocentre study of 222 patientsSabrina Dadoun
Paris Descartes University, Paris, France
Clin Exp Rheumatol 29:1010-3. 2011..To assess the frequency and effectiveness of switching TNF blockers in spondyloarthritis, and the predisposing factors of this effectiveness...
Nonsteroidal antiinflammatory drug intake according to the Assessment of SpondyloArthritis International Society Score in clinical trials evaluating tumor necrosis factor blockers: example of etanercept in advanced ankylosing spondylitisMaxime Dougados
Paris Descartes University, UPRES EA 4058, AP HP, Cochin Hospital, Paris 14, France
Arthritis Care Res (Hoboken) 64:290-4. 2012..To evaluate the interest of the Assessment of SpondyloArthritis international Society (ASAS) nonsteroidal antiinflammatory drug (NSAID) score as a quality indicator and a potential outcome measure in clinical studies...
Reporting of adherence to medication in recent randomized controlled trials of 6 chronic diseases: a systematic literature reviewLaure Gossec
AP HP, Rheumatology B Department, Cochin Hospital, 27 rue du Faubourg St Jacques, Paris 5 University, Paris, France
Am J Med Sci 334:248-54. 2007....
Minimal clinically important difference, low disease activity state, and patient acceptable symptom state: methodological issuesFlorence Tubach
, Biostatistique et Recherche Clinique, Groupe Hospitalier Bichat-Claude Bernard (AP-HP, INSERM U738, , Paris, France
J Rheumatol 32:2025-9. 2005..Threshold values for the MCID and LDAS should be determined according to data-driven and experts' opinions and approaches...
OMERACT/OARSI initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritisLaure Gossec
Medicine Faculty, Paris 5 René Descartes University AP HP, Cochin Hospital, Department of Rheumatology B, Paris, France
J Rheumatol 34:1432-5. 2007..quot;..
Reproducibility and sensitivity to change of various methods to measure joint space width in osteoarthritis of the hip: a double reading of three different radiographic views taken with a three-year intervalEmmanuel Maheu
Service de Rhumatologie, Hopital Saint Antoine, Paris, France
Arthritis Res Ther 7:R1375-85. 2005..6 or greater for assessing JSN over three years. Selecting a single reader was the most accurate method, with 0.3 mm precision. Using this cutoff, 50% of patients were classified as 'progressors'...
Antisynthetases syndrome associated with right heart failureLatifa Tahiri
Rheumatology Service, Cochin Hospital, Paris Descartes University, AP HP, 27, rue du Faubourg Saint Jacques, 75014 Paris, France
Joint Bone Spine 76:715-7. 2009..Treatment with corticosteroids rapidly improved both symptoms and biological abnormalities...
B cell activation biomarkers as predictive factors for the response to rituximab in rheumatoid arthritis: a six-month, national, multicenter, open-label studyJeremie Sellam
Hopital Bicetre, Assistance Publique Hopitaux de Paris, Le Kremlin Bicetre, France
Arthritis Rheum 63:933-8. 2011..To examine whether serum B cell markers can predict response to rituximab, a B cell-depleting monoclonal antibody, in patients with refractory rheumatoid arthritis (RA)...
Safety and efficacy of rituximab in systemic lupus erythematosus: results from 136 patients from the French AutoImmunity and Rituximab registryBenjamin Terrier
Bicetre Hospital, Assistance Publique Hopitaux de Paris, and Paris 11 University, Le Kremlin Bicetre, France
Arthritis Rheum 62:2458-66. 2010..However, in 2 recent randomized controlled trials (RCTs) of RTX, the primary end points were not met. We undertook this study to evaluate the safety and efficacy of RTX in off-trial patients with SLE seen in regular clinical practice...
Relative clinical influence of clinical, laboratory, and radiological investigations in early arthritis on the diagnosis of rheumatoid arthritis. Data from the French Early Arthritis Cohort ESPOIRLaure Gossec
Faculty of Medicine, Paris Descartes University, UPRES EA 4058, APHP, Department of Rheumatology B, Cochin Hospital, Paris, France
J Rheumatol 37:2486-92. 2010..To evaluate the relative level of influence of usual investigations in early arthritis on the diagnosis of rheumatoid arthritis (RA)...
The methods for handling missing data in clinical trials influence sample size requirementsGuy-Robert Auleley
, , , AP-HP, Paris, France
J Clin Epidemiol 57:447-53. 2004..CONCLUSIONS: These results can help investigators plan clinical trials to select the primary outcome and a priori specify the way missing data will be handled...
Frequency and tolerance of antituberculosis treatment according to national guidelines for prevention of risk of tuberculosis due to tumor necrosis factor blocker treatmentMarie Gaëlle Bray
Paris Descartes University, Medicine Faculty, UPRES EA 4058, 75651 Paris, France
Joint Bone Spine 77:135-41. 2010..However, its toxicity is unknown in this context and is a subject of debate...
HLA-B27 positive patients differ from HLA-B27 negative patients in clinical presentation and imaging: results from the DESIR cohort of patients with recent onset axial spondyloarthritisHo Yin Chung
Rheumatology, Leiden University Medical Centre, Leiden, The Netherlands
Ann Rheum Dis 70:1930-6. 2011..To clarify the influence of human leucocyte antigen B27 (HLA-B27) status on the phenotype of early axial spondyloarthritis (SpA)...
Effect of a collective educational program for patients with rheumatoid arthritis: a prospective 12-month randomized controlled trialJanine Sophie Giraudet-Le Quintrec
AP HP, Hopital Cochin, Universite Rene Descartes, Faculte de Medecine, Paris, France
J Rheumatol 34:1684-91. 2007..To evaluate the effect on health and functional status of an 8-week group-education program for rheumatoid arthritis (RA) in addition to usual medical care...
Practice patterns in outpatient rheumatology: a pilot evaluation of medical file contentJacques Fechtenbaum
Rheumatology Department B, Cochin Teaching Hospital, AP HP, and René Descartes Paris V University, Paris, France
Joint Bone Spine 74:171-4. 2007..Subsequently, one of the RHEVER members investigated whether these recommendations were followed by RHEVER participants at a teaching hospital...
Leflunomide in clinical practicePatricia Pinto
Rene Descartes University, Medicine Faculty, France
Acta Reumatol Port 31:215-24. 2006..This article reviews the place of LEF in clinical practice and outlines its potential applications beyond the officially recognized indication: rheumatoid arthritis (RA)...
Do intra-articular therapies work and who will benefit most?Laure Gossec
Service de Rhumatologie B, Hopital Cochin, Rene Descartes University, 27 rue du Faubourg Saint Jacques, 75014 Paris, France
Best Pract Res Clin Rheumatol 20:131-44. 2006..Some data--mainly from animal studies--suggest a possible long-term chondroprotective effect of hyaluronan. This treatment seems more efficacious in non-radiologically severe osteoarthritis with no or mild effusion...
The use of glucosamine therapy in osteoarthritisDjamila Zerkak
Rheumatology B Department, Rene Descartes University, AP HP Cochin Hospital, 27 rue du Faubourg Saint Jacques, Paris 75014, France
Curr Pain Headache Rep 8:507-11. 2004..An ongoing long-term clinical trial in the US will possibly permit to investigate the clinical relevance of these results and give appropriate recommendations...
Efficacy and safety of rituximab in the treatment of refractory inflammatory myopathies in adults: results from the AIR registryMarion Couderc
Rheumatology Department, CHU, Clermont Ferrand, France
Rheumatology (Oxford) 50:2283-9. 2011..Conclusions. RTX was well tolerated and had some beneficial effects on patients with IIM, the main limitation of this study resulted in a lack of manual muscle testing...
Recommendations of the French Society for Rheumatology regarding TNFalpha antagonist therapy in patients with rheumatoid arthritisBruno Fautrel
Pierre and Marie Curie University Paris VI, UFR de Medecine, France
Joint Bone Spine 74:627-37. 2007..To update French Society for Rheumatology guidelines regarding the use of TNFalpha antagonists for treating patients with rheumatoid arthritis (RA)...
Anti-tumor necrosis factor alpha therapy in fifteen patients with AA amyloidosis secondary to inflammatory arthritides: a followup report of tolerability and efficacyJacques-Eric Gottenberg
, Paris, France
Arthritis Rheum 48:2019-24. 2003....
Why and how to use NSAIDs in osteoarthritisMaxime Dougados
Medicine Faculty, Rene Descartes University, and Rheumatology B Department, AP HP Cochin Hospital, Paris, France
J Cardiovasc Pharmacol 47:S49-54. 2006....
Recommendations of the French Society for Rheumatology. TNFalpha antagonist therapy in rheumatoid arthritisBruno Fautrel
Service de Rhumatologie, Groupe Hospitalier Pitie Salpetriere, UFR de Medecine, Universite Pierre et Marie Curie Paris VI, 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
Joint Bone Spine 73:433-41. 2006..To develop recommendations for TNFalpha-antagonist therapy in patients with rheumatoid arthritis (RA) seen in everyday practice, under the aegis of the French Society for Rheumatology...
Evaluation of disease activity assessments in patients with rheumatoid arthritis and an inadequate response to anti-TNF therapy: analyses of abatacept clinical trial dataM Dougados
Rene Descartes University, Medicine Faculty, Hospital Cochin, Rheumatology B Department, Paris, France
Clin Exp Rheumatol 28:258-60. 2010....
Significant linkage to spondyloarthropathy on 9q31-34Corinne Miceli-Richard
Laboratoire de Génétique des Maladies Inflammatoires de l Intestin et Fondation Jean Dausset CEPH, Paris, France
Hum Mol Genet 13:1641-8. 2004..87, LOD=5.15, P=0.00002). This result provides evidence for the presence of a non-MHC susceptibility locus for SpA mapping to 9q31-34...
Pharmacological management of early rheumatoid arthritis--does combination therapy improve outcomes?Maxime Dougados
Hĵpital Cochin, Department of Rheumatology, Paris, France
J Rheumatol Suppl 66:20-6. 2002..Collectively, these data are beginning to shed light on how to best treat early RA, suggesting that DMARD work best when given very early...
Outcome variables for osteoarthritis clinical trials: The OMERACT-OARSI set of responder criteriaThao Pham
, AP-HP, Rheumatology B Department, Cochin Hospital, Paris, France
J Rheumatol 30:1648-54. 2003..The conclusions of the task force were presented and discussed during the OMERACT 6 conference, where a simplified set of responder criteria (OMERACT-OARSI set of criteria) was proposed...
Assessment of peripheral enthesitis in the spondylarthropathies by ultrasonography combined with power Doppler: a cross-sectional studyRoula Said-Nahal
Cochin Hospital, INSERM, CNRS, , AP-HP, Paris, France
Arthritis Rheum 48:523-33. 2003..The presence of entheseal involvement was independent of SpA subtype, but its degree of severity appeared to be greater in peripheral forms. US could be very useful for both the diagnosis and the assessment of SpA activity...
Selecting criteria for monitoring patients with rheumatoid arthritisMartin Soubrier
Service de Rhumatologie, Rheumatology Department, G Montpied Teaching Hospital, Place Henri Dunant, B P 69, 63003 Clermont Ferrand, France
Joint Bone Spine 72:129-34. 2005..A standardized follow-up protocol is suggested as a means of achieving greater uniformity in clinical practice...
Comparison of a computer based method and the classical manual method for radiographic joint space width assessment in hip osteoarthritisJean Francis Maillefert
, Institute of Rheumatology, Paris, France
J Rheumatol 29:2592-6. 2002..CONCLUSION: These results suggest that both techniques are reliable and sensitive enough to detect changes in a relevant percentage of patients with hip OA after a 3 year followup...
Evaluation of the smallest detectable difference in outcome or process variables in ankylosing spondylitisGuy-Robert Auleley
, , Paris, France
Arthritis Rheum 47:582-7. 2002..Evaluation of the SDD of the symptomatic outcome or process variables is a starting point to determine the minimum clinically important difference, permitting the presentation of results of clinical studies on an individual basis...
Spondyloarthropathy for practicing rheumatologists: diagnosis, indication for disease-controlling antirheumatic therapy, and evaluation of the responseCorinne Miceli-Richard
Department of Rheumatology, , Cochin Hospital, 27 rue du Faubourg Saint-Jacques, 75014 Paris, France
Rheum Dis Clin North Am 29:449-62. 2003....
Characterization and functional consequences of underexpression of clusterin in rheumatoid arthritisValerie Devauchelle
Institut Cochin, Departement d Immunologie, 27 rue du Faubourg Saint Jacques, 75674 Paris Cedex 14, France
J Immunol 177:6471-9. 2006..We propose that in RA joints, high levels of extracellular CLU and low expression of intracellular CLU may enhance NF-kappaB activation and survival of the synoviocytes...
Leflunomide for the treatment of rheumatoid arthritisCorinne Miceli-Richard
Cochin Hospital, AP-HP, , Paris, France
Expert Opin Pharmacother 4:987-97. 2003..Further trials are now required to confirm efficacy and safety of this drug in combination with other agents...
Chondrocalcinosis secondary to hypomagnesemia in Gitelman's syndromeHang Korng Ea
Rheumatology Department, Rene Descartes University, France
J Rheumatol 32:1840-2. 2005..Additionally, the association between GS (NCCT inactivation) and high bone mineral density provides a new insight into the possible role of thiazides in osteoporosis management...
Monitoring osteoarthritis progression and therapyMaxime Dougados
Université René Descarte and Hôpital Cochin, Paris, France
Osteoarthritis Cartilage 12:S55-60. 2004..The requirement for total hip arthroplasty has been evaluated as a composite outcome measure for trials of hip OA and found to be valid, simple, and clinically pertinent...
Flory syndrome or lymphomonocytic/low-neutrophil oligoarthritis: a diagnosis or a prognosis?Bernard Amor
Rheumatology Department, Hopital Cochin, 27, rue du Faubourg Saint Jacques, 75014 Paris, France
Joint Bone Spine 70:122-7. 2003..To individualize a new clinical entity of chronic arthritis and/or a factor indicating good prognosis of chronic arthritis...
[Rheumatology, prospects of development]Maxime Dougados
Service de Rhumatologie B, , 27, rue du Faubourg Saint-Jacques, 75014 Paris
Presse Med 33:Sp111-4. 2004
How can one develop disease-modifying drugs in osteoarthritis?Maxime Dougados
Rene Descartes University, Cochin Hospital, 27 rue du Faubourg, Saint Jacques, 75014 Paris, France
Curr Rheumatol Rep 7:22-8. 2005....
A composite index for total hip arthroplasty in patients with hip osteoarthritisJean Francis Maillefert
Institute of Rheumatology, , Cochin Hospital, Paris, France
J Rheumatol 29:347-52. 2002..On the other hand, the high negative predictive values suggest that these composite measures should be used by clinicians to determine which patients should not be referred to THA...
Ankylosing spondylitis: how should the disease be assessed?Maxime Dougados
, Cochin Hospital, Paris, France
Best Pract Res Clin Rheumatol 16:605-18. 2002..Other investigations are required in order to obtain relevant instruments for other domains, such as structural severity...
Reliability of ultrasonography to detect synovitis in rheumatoid arthritis: a systematic literature review of 35 studies (1,415 patients)Peter P Cheung
Paris Descartes University, Cochin Hospital, Paris, France
Arthritis Care Res (Hoboken) 62:323-34. 2010..US is a sensitive method for synovitis detection. However, reliability is still a key concern...
Outcome measures for clinical trials of disease modifying osteoarthritis drugs in patients with hip osteoarthritisMaxime Dougados
Service de Rhumatologie, , 27 Rue du Faubourg St-Jacques, Paris 75014, France
J Rheumatol Suppl 70:66-9. 2004
New concepts in the diagnosis and treatment of recent-onset polyarthritisNouha Raissouni
Rheumatology Department B, Cochin Teaching Hospital, 27 rue du Faubourg Saint Jacques, 75679 Paris Cedex 14, France
Joint Bone Spine 72:119-23. 2005..We used data from a comprehensive literature review to develop a diagnostic and therapeutic strategy for incipient undifferentiated inflammatory joint disease...
The use of glucosamine therapy in osteoarthritisDjamila Zerkak
Rheumatology B Department, , AP-HP Cochin Hospital, 27 rue du Faubourg Saint Jacques, Paris 75014, France
Curr Rheumatol Rep 6:41-5. 2004..An ongoing long-term clinical trial in the US will possibly permit to investigate the clinical relevance of these results and give appropriate recommendations...
New tools for diagnosing spondyloarthropathySamira Rostom
UPRES EA 4058, département de rhumatologie B, Faculte de Medecine, Hopital Cochin, AP HP, Universite Paris Descartes, 27, rue du Faubourg St Jacques, 75014 Paris, France
Joint Bone Spine 77:108-14. 2010..The Assessment of SpondyloArthritis international Society (ASAS) has just issued new diagnostic criteria for AS that performed well in a large cohort of patients with recent-onset low back pain...
Evaluation of the efficacy of etoricoxib in ankylosing spondylitis: results of a fifty-two-week, randomized, controlled studyDesiree van der Heijde
Department of Internal Medicine, Division of Rheumatology, University Hospital, Maastricht, The Netherlands
Arthritis Rheum 52:1205-15. 2005..To assess the efficacy, safety, and tolerability of etoricoxib, a cyclooxygenase 2 (COX-2) selective inhibitor, administered continuously over 52 weeks for the treatment of ankylosing spondylitis (AS)...
Lefunomide in combination therapyJoachim R Kalden
Department of Internal Medicine III, Universitaet Erlangen Nuremberg, Erlangen, Germany
J Rheumatol Suppl 71:25-30. 2004..The Expert Panel concluded that combination therapy with leflunomide has a place in the treatment of RA. Caution is advised, however, when using combination treatments and, therefore, the patient's safety should be carefully monitored...
