Research Topics
| B DesoizeSummaryCountry: France Publications
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Detail Information
Publications
Cell culture as spheroids: an approach to multicellular resistanceB Desoize
Laboratoire de Biochimie, IFR53 Biomolecules, Faculte de Pharmacie, Reims, France
Anticancer Res 18:4147-58. 1998..The mechanism of action of this new pharmacological class is the disruption of the cell adhesion forces...
Puzzles in the clinical pharmacokinetics of fluorouracilB Desoize
IFR53 EA2063, Laboratoire de Biochimie, Reims, France
Anticancer Res 18:4607-10. 1998....
Multicellular resistance: a paradigm for clinical resistance?B Desoize
Laboratoire de Biochimie et de Biologie Moleculaire, Faculte de Pharmacie, IFR 51, EA 2063, Reims, France
Crit Rev Oncol Hematol 36:193-207. 2000..The explanation given is that it improves drug penetration into spheroids. We now hypothesise that hyaluronidase, in fact, decreases MCR and thus could be the first member of a new therapeutic class...
Metals and metal compounds in cancer treatmentBernard Desoize
Laboratoire de Biochimie et de Biologie Moleculaire, EA 3306, IFR 53, Faculte de Pharmacie, 51 rue Cognacq Jay, 51096 Reims Cedex, France
Anticancer Res 24:1529-44. 2004..The last metal reviewed, platinum, has given some of the very best anti-cancer drugs. Four derivatives are used today in the clinic; their mechanism of action and of resistance are described...
Metals and metal compounds in carcinogenesisBernard Desoize
Laboratoire de Biochimie et de Biologie Moleculaire, Faculte de Pharmacie, 51 Rue Cognac Jay, IFR 53, EA 3306, 51096 Reims, France
In Vivo 17:529-39. 2003..Magnesium deficiency and iron excess are not exactly carcinogenetic, but certain concentrations of these metal ions are needed to prevent cancer...
Particular aspects of platinum compounds used at present in cancer treatmentBernard Desoize
Laboratoire de Biochimie et de Biologie Moleculaire, EA 3306, Faculte de Pharmacie, IFR 53, 51 rue Cognacq Jay, Reims, France
Crit Rev Oncol Hematol 42:317-25. 2002..Oxaliplatin give interesting results in a number of cancers. The official recommendation in Japan for nedaplatin is head and neck, testicular, lung, oesophageal, ovarian, and cervical cancer...
Gallium in cancer treatmentPhilippe Collery
Service de cancérologie, Polyclinique Maymard, rue Marcel Paul, Bastia, France
Crit Rev Oncol Hematol 42:283-96. 2002..Although not as potent as platinum in vitro, the anticancer activity of Ga should not be ignored, but the schedule of administration still needs to be optimised and new compounds are now under clinical investigations...
Cancer and metals and metal compounds: part II--cancer treatmentBernard Desoize
Crit Rev Oncol Hematol 42:213-5. 2002
Cancer and metals and metal compounds: part I--carcinogenesisBernard Desoize
Crit Rev Oncol Hematol 42:1-3. 2002
Stromal reaction and tumour growthBernard Desoize
Crit Rev Oncol Hematol 49:173-6. 2004
Immunosuppressive agents are also carcinogensBernard Desoize
Crit Rev Oncol Hematol 56:1-4. 2005
"Antibodies in cancer treatment"Bernard Desoize
Crit Rev Oncol Hematol 62:23-5. 2007
Imaging and cancer--IBernard Desoize
Crit Rev Oncol Hematol 68:37-8. 2008
