S Desagher

Summary

Country: France

Publications

  1. ncbi Mitochondria as the central control point of apoptosis
    S Desagher
    UPR CNRS 9023, CCIPE, 141 rue de la Cardonille, F 34094 Montpellier Cedex 5, France
    Trends Cell Biol 10:369-77. 2000
  2. ncbi Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane
    R Eskes
    Serono Pharmaceutical Research Institute, Ares Serono International S A, CH 1228 Plan les Ouates, Geneva, Switzerland
    Mol Cell Biol 20:929-35. 2000
  3. ncbi Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8
    S Desagher
    CNRS UPR 9023, Montpellier, France
    Mol Cell 8:601-11. 2001

Collaborators

Detail Information

Publications3

  1. ncbi Mitochondria as the central control point of apoptosis
    S Desagher
    UPR CNRS 9023, CCIPE, 141 rue de la Cardonille, F 34094 Montpellier Cedex 5, France
    Trends Cell Biol 10:369-77. 2000
    ..Here, we attempt to summarize our current view of the mechanisms that lead to the efflux of many proteins from mitochondria during apoptosis and the role played by Bcl-2 family proteins in the control of this event...
  2. ncbi Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane
    R Eskes
    Serono Pharmaceutical Research Institute, Ares Serono International S A, CH 1228 Plan les Ouates, Geneva, Switzerland
    Mol Cell Biol 20:929-35. 2000
    ..Bax mitochondrial membrane insertion triggered by Bid may represent a key step in pathways leading to apoptosis...
  3. ncbi Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8
    S Desagher
    CNRS UPR 9023, Montpellier, France
    Mol Cell 8:601-11. 2001
    ..Moreover, a mutant of Bid that cannot be phosphorylated was found to be more toxic than wild-type Bid. Together, these data indicate that phosphorylation of Bid represents a new mechanism whereby cells control apoptosis...