Research Topics
| Jean Philippe DavidSummaryCountry: France Publications
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Detail Information
Publications
Exploring the molecular basis of insecticide resistance in the dengue vector Aedes aegypti: a case study in Martinique Island (French West Indies)Sebastien Marcombe
Laboratoire de Lutte contre les Insectes Nuisibles LIN, Institut de Recherche Pour le Développement IRD Montpellier, France
BMC Genomics 10:494. 2009..Resistance of Ae. aegypti to chemical insecticides has been reported worldwide and the underlying molecular mechanisms, including the identification of enzymes involved in insecticide detoxification are not completely understood...
Transcriptome response to pollutants and insecticides in the dengue vector Aedes aegypti using next-generation sequencing technologyJean Philippe David
Laboratoire d Ecologie Alpine LECA, UMR 5553 CNRS Université Grenoble, France
BMC Genomics 11:216. 2010....
Involvement of cytochrome P450 monooxygenases in the response of mosquito larvae to dietary plant xenobioticsJ P David
Laboratoire d Ecologie Alpine LECA UMR 5553, Bâtiment D, rue de la Piscine, Universite Joseph Fourier, BP53, 38041 Grenoble Cedex 9, France
Insect Biochem Mol Biol 36:410-20. 2006..The role of CYP genes in tolerance to natural xenobiotics and the importance of such adaptive responses in the capacity of mosquitoes to colonize new habitats and to develop insecticide resistance mechanisms are discussed...
Cross-induction of detoxification genes by environmental xenobiotics and insecticides in the mosquito Aedes aegypti: impact on larval tolerance to chemical insecticidesRodolphe Poupardin
Laboratoire d Ecologie Alpine, UMR CNRS Université Joseph Fourier 5553, Equipe Perturbations Environnementales et Xénobiotiques, Domaine Universitaire de Saint Martin d Hères 2233, rue de la piscine Bât D Biologie, BP 53, 38041 Grenoble Cedex 9, France
Insect Biochem Mol Biol 38:540-51. 2008..Molecular mechanisms involved and impact on mosquito control strategies are discussed...
Response of Aedes aegypti (Diptera: Culicidae) larvae to three xenobiotic exposures: larval tolerance and detoxifying enzyme activitiesSebastien Boyer
UMR Unité Mixte de Recherche 5553 Laboratoire d Ecologie Alpine, Universite Joseph Fourier, BP 53, 38041 Grenoble Cedex 9, France
Environ Toxicol Chem 25:470-6. 2006..Both induction and selection increased larval tolerance to the xenobiotics used and increased the levels of larval detoxifying enzyme activities...
Genome scan in the mosquito Aedes rusticus: population structure and detection of positive selection after insecticide treatmentMargot Paris
Laboratoire d Ecologie Alpine, CNRS UMR 5553, Universite Joseph Fourier, BP 53, 38041 Grenoble Cedex 09, France
Mol Ecol 19:325-37. 2010..Furthermore, this signal was detectable using genomic tools before any toxicological evidence for resistance could be identified...
Candidate genes revealed by a genome scan for mosquito resistance to a bacterial insecticide: sequence and gene expression variationsAurelie Bonin
Laboratoire d Ecologie Alpine, CNRS UMR 5553, Universite Joseph Fourier, BP 53, 38041 Grenoble Cedex 09, France
BMC Genomics 10:551. 2009..israelensis (Bti) insecticidal toxins...
Impact of glyphosate and benzo[a]pyrene on the tolerance of mosquito larvae to chemical insecticides. Role of detoxification genes in response to xenobioticsMuhammad Asam Riaz
Laboratoire d Ecologie Alpine LECA, UMR CNRS 5553, Equipe Perturbation Environnementales et Xenobiotiques, France
Aquat Toxicol 93:61-9. 2009..Overall, this study reveals the potential of benzo[a]pyrene and glyphosate to affect the tolerance of mosquito larvae to chemical insecticides, possibly through the cross-induction of particular genes encoding detoxification enzymes...
Fitness costs of resistance to Bti toxins in the dengue vector Aedes aegyptiMargot Paris
Laboratoire d Ecologie Alpine, UMR CNRS 5553, Universite Joseph Fourier, BP 53, 38041, Grenoble Cedex 09, France
Ecotoxicology 20:1184-94. 2011..We discuss the implications of our findings in terms of sustainable management strategies in light of the challenge of preserving the long-term efficiency of this environmentally safe anti-mosquito bio-insecticide...
Transcription profiling of eleven cytochrome P450s potentially involved in xenobiotic metabolism in the mosquito Aedes aegyptiR Poupardin
Laboratoire d Ecologie Alpine LECA, UMR 5553 CNRS Université Grenoble, France
Insect Mol Biol 19:185-93. 2010..Overall, this study revealed that these P450s show different transcription profiles according to xenobiotic exposures, life stages or sex. Their putative chemoprotective functions are discussed...
The evolutionary ecology of insect resistance to plant chemicalsLaurence Despres
Laboratoire d Ecologie Alpine, LECA UMR CNRS 5553, Universite Joseph Fourier, BP 53 38041, Grenoble Cedex 09, France
Trends Ecol Evol 22:298-307. 2007....
The role of environment in shaping the genetic diversity of the subalpine mosquito, Aedes rusticus (Diptera, Culicidae)J P David
, Centre de Biologie Alpine, , BP 53, F-38041 Grenoble Cedex 9, France
Mol Ecol 12:1951-61. 2003..Such a dynamic adaptation is also suggested by the correlation between geographical and toxicological distances and the correlation between dietary tolerance to the leaf-litter toxic polyphenols and annual larvicidal treatments...
A MITE-based genotyping method to reveal hundreds of DNA polymorphisms in an animal genome after a few generations of artificial selectionAurelie Bonin
Laboratoire d Ecologie Alpine, CNRS UMR 5553, Universite Joseph Fourier, BP 53, 38041 Grenoble Cedex 09, France
BMC Genomics 9:459. 2008....
Involvement of ligninlike compounds in toxicity of dietary alder leaf litter against mosquito larvaeJ P David
, 38041 Grenoble Cedex 9, France
J Chem Ecol 27:161-74. 2001..These results are discussed in relation to a possible mode of action of lignins in the plant-mosquito interactions...
Mosquito larval consumption of toxic arborescent leaf-litter, and its biocontrol potentialJ P David
, Centre de Biologie Alpine, , BP 53, 38041 Grenoble Cedex 9, France
Med Vet Entomol 17:151-7. 2003..Possibilities for mosquito larval control with toxic leaf-litter products and the need for standardized ingestion bioassays of larvicidal particles are discussed...
