Research Topics
| J ClementySummaryCountry: France Publications
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Publications
Atrial fibrillatory cycle length: computer simulation and potential clinical importanceMichel Haissaguerre
Hôpital Cardiologique du Haut Lévêque and University of Bordeaux II, Bordeaux, France
Europace 9:vi64-70. 2007..In this study, a computer model and clinical data on human subjects undergoing catheter ablation for paroxysmal and persistent AF were used to determine the clinical potential of AFCL...
High-resolution mapping of tachycardia originating from the superior vena cava: evidence of electrical heterogeneity, slow conduction, and possible circus movement reentryDipen C Shah
Hopital Cardiologique du Haut Leveque, Bordeaux, France
J Cardiovasc Electrophysiol 13:388-92. 2002..These findings may suggest a similar substrate and arrhythmia mechanism in the myocardium of the pulmonary veins...
Mapping and ablation of idiopathic ventricular fibrillationMichel Haissaguerre
Hopital Haut Leveque, Bordeaux Pessac, France
Circulation 106:962-7. 2002..Ventricular fibrillation is the main mechanism of sudden cardiac death. The feasibility of eliminating recurrent episodes by catheter ablation has not been reported...
Pulmonary vein ablation using the LocaLisa nonfluoroscopic mapping systemRukshen Weerasooriya
, Bordeaux-Pessac, France
J Cardiovasc Electrophysiol 14:112. 2003
Electrophysiologically guided pulmonary vein isolation during sustained atrial fibrillationLaurent Macle
Service du Professeur Clementy, Hopital Cardiologique du Haut Leveque, Bordeaux Pessac, France
J Cardiovasc Electrophysiol 14:255-60. 2003..Sustained atrial fibrillation (AF) is frequently encountered during pulmonary vein (PV) isolation. The aim of this study was to evaluate the feasibility and safety of PV isolation during sustained AF...
Dissociated pulmonary vein arrhythmia: incidence and characteristicsRukshen Weerasooriya
Service du Professeur Clementy Room 338, 3rd West, Hopital Cardiologique du Haut Leveque, Avenue de Magellan, Bordeaux Pessac 33604, France
J Cardiovasc Electrophysiol 14:1173-9. 2003..The incidence and characteristics of dissociated arrhythmia confined to the pulmonary vein (PV) following disconnection have not been described in a large number of patients with paroxysmal atrial fibrillation...
Changes in atrial fibrillation cycle length and inducibility during catheter ablation and their relation to outcomeMichel Haissaguerre
Hopital Cardiologique du Haut Leveque, Avenue de Magellan, 33604 Bordeaux, France
Circulation 109:3007-13. 2004..The modification of atrial fibrillation cycle length (AFCL) during catheter ablation in humans has not been evaluated...
Catheter ablation of long-lasting persistent atrial fibrillation: critical structures for terminationMichel Haissaguerre
Hopital Cardiologique du Haut Leveque, Bordeaux Pessac, France
J Cardiovasc Electrophysiol 16:1125-37. 2005..The relative contributions of different atrial regions to the maintenance of persistent atrial fibrillation (AF) are not known...
Catheter ablation of long-lasting persistent atrial fibrillation: clinical outcome and mechanisms of subsequent arrhythmiasMichel Haissaguerre
Hopital Cardiologique du Haut Leveque, Bordeaux Pessac, France
J Cardiovasc Electrophysiol 16:1138-47. 2005..The clinical outcome and subsequent arrhythmia recurrence after using an ablation method targeting multiple left atrial sites with the aim of achieving acute AF termination has not been characterized...
Localized sources maintaining atrial fibrillation organized by prior ablationMichel Haissaguerre
Hopital Cardiologique du Haut Leveque, University Victor Segalen, Bordeaux, France
Circulation 113:616-25. 2006..Endocardial mapping of localized sources driving atrial fibrillation (AF) in humans has not been reported...
[Arrhythmias in sleep apnea syndrome]Jacques Clementy
Service de cardiologie médicale E, Hopital Cardiologique du Haut Leveque, Pessac Cedex, France
Presse Med 36:1012-5. 2007..Continuous positive airway pressure (CPAP) reduces arrhythmias significantly...
Successful ablation of Hisian ectopy identified by a reversed His bundle activation sequenceKee Joon Choi
Hopital Cardiologique du Haut Leveque, Bordeaux Pessac, France
J Interv Card Electrophysiol 6:183-6. 2002..Low power RF energy delivered to the site of earliest activation completely abolished the ectopic activity without modification of Hisian or atrioventricular conduction. After a 12-month followup, the patient remains free of recurrence...
Electrogram polarity reversal as an additional indicator of breakthroughs from the left atrium to the pulmonary veinsTeiichi Yamane
Hopital Cardiologique du Haut Leveque, Bordeaux Pessac, France
J Am Coll Cardiol 39:1337-44. 2002..We assessed the anatomical distribution and electrogram characteristics of breakthrough from the left atrium (LA) to the pulmonary veins (PVs)...
Multiple sources initiating atrial fibrillation from a single pulmonary vein identified by a circumferential catheterM Hocini
Hopital du Haut leveque, CHU de Bordeaux, France
Pacing Clin Electrophysiol 23:1828-31. 2000..Simultaneous electrogram recordings with a circumferential PV catheter identified the presence of multiple arrhythmogenic foci within a single PV...
Pseudo sinus rhythm originating from the left superior pulmonary vein in a patient with paroxysmal atrial fibrillationT Yamane
Hopital Cardiologique du Haut Leveque, Bordeaux, France
J Cardiovasc Electrophysiol 12:1190-1. 2001..Radiofrequency applications inside the left superior pulmonary vein eliminated both atrial fibrillation and the ectopic pacemaker...
Concealed left pulmonary vein potentials unmasked by left atrial stimulationM Hocini
Hopital Haut Leveque, CHU de Bordeaux, France
Pacing Clin Electrophysiol 23:1832-5. 2000..Distal CS or LA pacing is required to recognize left PVPs in approximately 2/3 of patients and facilitates RF ablation...
Electrophysiologically guided ablation of the pulmonary veins for the curative treatment of atrial fibrillationD C Shah
Hospital Haut Leveque, Bordeaux Pessac, France
Ann Med 32:408-16. 2000..It is anticipated that continued technological development will improve and facilitate this technique of curative treatment of AF...
Validation by serial standardized testing of a new rate-responsive pacemaker sensor based on variations in myocardial contractilityJ Clementy
H pital Cardiologique du Haut Lévêque, Département d Electrophysiologie et Stimulation Cardiaque, Pessac, France
Europace 3:124-31. 2001..This study compared the chronotropic performance of such devices implanted in 14 patients suffering from chronotropic incompetence with that observed in 18 control subjects in normal sinus rhythm...
[Identification of candidates for multisite pacing: results and presumed mechanisms of action after five years experience]S Reuter
Département d electrophysiologie et de stimulation cardiaque, Service du Pr Clementy, Hopital Cardiologique du Haut Leveque, Avenue de Magellan, 33604 Pessac
Arch Mal Coeur Vaiss 99:155-63. 2006..Echocardiography allows observation of electromechanical delay and opens new perspectives in the future for selecting patients for pacing. Ar..
[Catheter ablation of paroxysmal atrial fibrillation]F Sacher
Hopital Cardiologique du Haut Leveque, Bordeaux Pessac
Arch Mal Coeur Vaiss 97:949-56. 2004..We investigate the feasibility and results of combined pulmonary vein and linear ablation utilizing a specific linear lesion connecting the lateral mitral annulus to the left inferior pulmonary vein (left isthmus)...
[Asynchronism and right ventricular pacing]J B Thambo
Hopital Cardiologique du Haut Leveque, service des maladies cardiovasculaires congénitales de l enfant et de l adulte, Pessac
Arch Mal Coeur Vaiss 98:519-23. 2005..We assessed the impact of apical ventricular pacing on echocardiographic ventricular dyssynchrony and hemodynamic parameters...
Comparison of chronic biventricular pacing between epicardial and endocardial left ventricular stimulation using Doppler tissue imaging in patients with heart failureS Garrigue
Hopital Cardiologique du Haut Leveque, University of Bordeaux, Bordeaux Pessac, France
Am J Cardiol 88:858-62. 2001..Thus, in heart failure patients with BVP, endocardial BVP provides more homogenous intraventricular resynchronization than epicardial BVP and is associated with better LV filling and systolic performance...
Is there a synergic effect of propafenone associated with atrial overdrive pacing for atrial arrhythmia prevention? A randomised crossover studyS Garrigue
Hopital Cardiologique du Haut Leveque, University of Bordeaux, 19 avenue de Magellan, 33600 Pessac, France
Heart 83:172-7. 2000..To assess the effect of adding propafenone to atrial overdrive for the prevention of atrial arrhythmia episodes in patients with DDD pacemakers...
Transvenous left atrial and left ventricular pacing in Ebstein's anomaly with severe interatrial conduction blockS Garrigue
Hopital Cardiologique du Haut Leveque, University of Bordeaux, Bordeaux Pessac, France
Pacing Clin Electrophysiol 24:1032-5. 2001..This case illustrates the promising possibility to circumvent the interatrial conduction block with single left atrial pacing instead of biatrial pacing which was not suitable here...
Comparison of permanent left ventricular and biventricular pacing in patients with heart failure and chronic atrial fibrillation: prospective haemodynamic studyS Garrigue
Hopital Cardiologique du Haut Leveque, University of Bordeaux, Bordeaux Pessac, France Sorin Biomedica, 9, rue Georges Besse, Bat 4, 92160 Antony, France
Heart 87:529-34. 2002....
[Radiofrequency ablation of atrial fibrillation]M Hocini
Service de cardiologie, Hopital Cardiologique du Haut Leveque, Avenue de Magellan, 33604 Pessac, France
Ann Cardiol Angeiol (Paris) 52:258-63. 2003..Some comparative studies with medical treatment are currently evaluating their efficacy, safety and respective cost and they may lead to a considerable increase in the number of patients who could benefit from these curative treatments...
[Mapping and ablation of malignant ventricular arrhythmias]M Hocini
Hopital Cardiologique du Haut Leveque, Avenue de Magellan, 33604 Pessac
Arch Mal Coeur Vaiss 98:34-41. 2005..The clinical results were spectacular: 88% of patients had no further episodes of ventricular fibrillation as demonstrated by analysis of the defibrillator with an average follow-up period of more than 34 months...
[Catheter ablation for atrial fibrillation]N Derval
Hopital Cardiologique du Haut Leveque, CHU Bordeaux, Avenue Magellan, Pessac, France
Ann Cardiol Angeiol (Paris) 58:S50-4. 2009..With constant improvement in this field catheter ablation has become a valuable tool in the management strategy of AF...
Echocardiographic advances in atrial fibrillation and supraventricular arrhythmiasM Rotter
Unit of Cardiology of Haut Lévêque, Victor Segalen University Bordeaux, Bordeaux, France
Minerva Cardioangiol 53:109-15. 2005..This review will summarize currently available technology of ICE and its indications and applications in electrophysiological procedures...
Interventricular and intra-left ventricular electromechanical delays in right ventricular paced patients with heart failure: implications for upgrading to biventricular stimulationP Bordachar
Hopital Cardiologique du Haut-Leveque, University of Bordeaux, Pessac, France
Heart 89:1401-5. 2003..In RVP patients, an interventricular electromechanical delay or intra-LV electromechanical delay > 50 ms reflects a significant ventricular mechanical asynchrony and should be required to select patients for upgrading to BVP...
[The place of ablation in the treatment of atrial fibrillation: where are we and where are we going?]P Jais
Service de Rythmologie, Hopital Cardiologique du Haut Leveque, Pessac
Arch Mal Coeur Vaiss 97:1071-7. 2004....
[Characterization of premature ventricular contraction initiating ventricular fibrillation]F Sacher
Université Bordeaux II CHU de Bordeaux Victor Segalen, Hopital Cardiologique du Haut Leveque, Bordeaux Pessac
Arch Mal Coeur Vaiss 98:867-73. 2005..005). CONCLUSION: PVC initiating VF demonstrate specific electrocardiographic features that facilitate determination of their origin. Ablation of these typical PVC is feasible in order to reduce ICD shock...
[Severity of aortic ring abscess complicated by cardiac conduction abnormalities]P L Massoure
Service de cardiologie, Hôpital des Armées R Picqué, Bordeaux, France
Ann Cardiol Angeiol (Paris) 54:132-7. 2005..To determine clinical features, management and prognosis of cardiac conduction abnormalities (CCA) complicating abscessed endocarditis...
[Sleep apnea and cardiac pacing: mechanisms of action and perspectives]S Garrigue
Hopital Cardiologique du Haut Leveque, 19, Avenue de Magellan, 33600 Bordeaux Pessac, France
Ann Cardiol Angeiol (Paris) 52:239-45. 2003..It is therefore possible that cardiac stimulation will become part of the treatment of sleep apnea in patients with documented bradycardia and/or heart failure...
Ambulatory measurement of the timing of Korotkoff sounds in a group of normal subjects: influence of age and heightP Gosse
Hôpital Saint André, Bordeaux, France
Am J Hypertens 12:231-5. 1999..This effectively eliminates the influence of height, which reflects the length of the arterial segment under investigation...
Significance of syncope in patients with Alzheimer's disease treated with cholinesterase inhibitorsP Bordier
Hopital Cardiologique du Haut Leveque, University of Bordeaux, Pessac, France
Europace 5:429-31. 2003..Pacemaker implantation seemed justified rather than donepezil cessation. More over, it permitted an increase in donepezil dosage...
Left ventricular mass is better correlated with arising blood pressure than with office or occasional blood pressureP Gosse
, Bordeaux, France
Am J Hypertens 10:505-10. 1997..A marked abrupt daily elevation in blood pressure on arising, then maintained for a certain time, could contribute to the development of left ventricular hypertrophy and may constitute a trigger for cardiovascular complications...
Daytime and nighttime ambulatory blood pressures should be calculated over the true sleep/waking cycle and not over arbitrary periodsP Gosse
, Bordeaux, France
Am J Hypertens 9:269-72. 1996....
[Fulguration of accessory pathways in children. Value of two-dimensional echocardiography]J Clementy
, Pessac
Arch Mal Coeur Vaiss 82:861-7. 1989..Transcatheter ablation seems to be feasible and safe enough to be offered as an alternative to surgery in the treatment of refractory reciprocating tachycardia in children...
Reduction in arterial distensibility in hypertensive patients as evaluated by ambulatory measurement of the QKD interval is correlated with concentric remodeling of the left ventricleP Gosse
Hôpital Saint André, Bordeaux, France
Am J Hypertens 12:1252-5. 1999..The concentric character of the LVH of the hypertensive patient was thus linked to the reduction in arterial distensibility...
[Role of electric stimulation in apnea syndromes]P Bordier
Hopital Cardiologique du Haut Leveque, Universite de Bordeaux II, Pessac, France
Arch Mal Coeur Vaiss 95:56-60. 2002..Therefore, there appears to be a field of research for cardiac pacing in apnoea syndromes. The authors review the principal reported data on the indications and possibilities of extra-cardiac and cardiac stimulation in apnoeic syndromes...
Impact of varying ablation patterns in a simulation model of persistent atrial fibrillationMartin Rotter
Hôpital Cardiologique du Haut Lévêque and Université Victor Segalean Bordeaux II, Bordeaux, France
Pacing Clin Electrophysiol 30:314-21. 2007..Evaluation of ablation patterns by computer simulation provides a tool for examination of its effectiveness and side effects...
Phase-rectified signal averaging: a useful tool for the estimation of the dominant frequency in ECG signals during atrial fibrillationMathieu Lemay
Conf Proc IEEE Eng Med Biol Soc 2007:35-8. 2007..The potential of phase-rectified analysis is demonstrated through experiments both on synthetic and clinical ECG signals...
Spatial dynamics of atrial activity assessed by the vectorcardiogram: from sinus rhythm to atrial fibrillationMathieu Lemay
Ecole Polytechique Federale de Lausanne, Signal Processing Institute, STI ITS LTS1, Station 11, CH 1015, Lausanne, Switzerland
Europace 9:vi109-18. 2007..This study aims at developing methods for extracting spatiotemporal information about the electric activity of the atria from electrocardiographic signals, in particular during atrial fibrillation...
Loading effect of fibroblast-myocyte coupling on resting potential, impulse propagation, and repolarization: insights from a microstructure modelVincent Jacquemet
Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
Am J Physiol Heart Circ Physiol 294:H2040-52. 2008..This complex, coupling-dependent interaction of fibroblast and myocytes also has relevance to the integration of other nonmyocytes in the heart, such as those used in cellular therapies...
A numerical scheme for modeling wavefront propagation on a monolayer of arbitrary geometrySteeve Zozor
Signal Processing Institute, EPFL, CH 1015 Lausanne, Switzerland
IEEE Trans Biomed Eng 50:412-20. 2003..The same matrix is used for both these quantities. We then give some results of simulation for simple monolayers and complex monolayers resembling a human atria...
Cancellation of ventricular activity in the ECG: evaluation of novel and existing methodsMathieu Lemay
Ecole Polytechnique Federale de Lausanne, Signal Processing Institute, Lausanne CH 1015, Switzerland
IEEE Trans Biomed Eng 54:542-6. 2007..ECG signals generated by a biophysical model as well as clinical ECG signals are used to evaluate the performance of the proposed methods in comparison to two standard ABS-based methods...
Analysis of electrocardiograms during atrial fibrillation. A biophysical model approachVincent Jacquemet
Lausanne Heart Group, EPFL, Switzerland
IEEE Eng Med Biol Mag 25:79-88. 2006
Wavelength and vulnerability to atrial fibrillation: Insights from a computer model of human atriaVincent Jacquemet
Signal Processing Institute, Ecole Polytechnique Federale de Lausanne EPFL, Station 11, Switzerland
Europace 7:83-92. 2005..To explain the contradictory results related to the concept of critical cardiac wavelength in the initiation and perpetuation of atrial fibrillation (AF)...
Adaptation of the standard 12-lead electrocardiogram system dedicated to the analysis of atrial fibrillationZenichi Ihara
Signal Processing Institute, Swiss Federal Institute of Technology Lausanne, Lausanne, Switzerland
J Electrocardiol 40:68.e1-8. 2007..The objective of the study was to design a lead system aimed at studying atrial fibrillation (AF), while being anchored to the standard 12-lead system...
Vectorcardiographic lead systems for the characterization of atrial fibrillationAdriaan van Oosterom
Department of Cardiology, Lausanne University Hospital Center, Lausanne, Switzerland
J Electrocardiol 40:343.e1-11. 2007..The aim of the study was to design a vectorcardiographic lead system dedicated to the analysis of atrial fibrillation (AF)...
Genesis of the P wave: atrial signals as generated by the equivalent double layer source modelAdriaan van Oosterom
Department of Cardiology, Centre Hospitalier Universitaire Vaudois CHUV, Lausanne, CH, Switzerland
Europace 7:21-9. 2005..To assess the effectiveness of the equivalent surface source model in the simulation of atrial signals as observed in ECG leads...
Study of unipolar electrogram morphology in a computer model of atrial fibrillationVincent Jacquemet
Signal Processing Institute, Swiss Federal Institute of Technology, Lausanne, Switzerland
J Cardiovasc Electrophysiol 14:S172-9. 2003..CONCLUSION: Analysis of the amplitude and symmetry of unipolar atrial electrograms can provide information about the electrophysiologic substrate maintaining AF...
Finite volume stiffness matrix for solving anisotropic cardiac propagation in 2-D and 3-D unstructured meshesVincent Jacquemet
Signal Processing Institute, Ecole Polytechnique Federale de Lausanne, CH 1015 Lausanne, Switzerland
IEEE Trans Biomed Eng 52:1490-2. 2005....
Pacemaker activity resulting from the coupling with nonexcitable cellsVincent Jacquemet
Signal Processing Institute, Ecole Polytechnique Federale de Lausanne, CH 1015 Lausanne, Switzerland
Phys Rev E Stat Nonlin Soft Matter Phys 74:011908. 2006..This may constitute a mechanism of focal sources triggering arrhythmias such as atrial fibrillation...
Modelling cardiac fibroblasts: interactions with myocytes and their impact on impulse propagationVincent Jacquemet
Department of Biomedical Engineering, Duke University, 260 Hudson Hall, Box 90281, Durham, NC 27708, USA
Europace 9:vi29-37. 2007..This study aims at investigating in a biophysical model how much coupling would be necessary to perturb significantly the electrical propagation of the cardiac impulse...
Steady-state solutions in mathematical models of atrial cell electrophysiology and their stabilityVincent Jacquemet
Signal Processing Institute, Ecole Polytechnique Federale de Lausanne EPFL, CH 1015 Lausanne, Switzerland
Math Biosci 208:241-69. 2007..The approach proposed in this paper assists in the exploration of the high-dimensional parameter space of the cell models and the identification of the conditions leading to spontaneous pacemaker activity...
