Research Topics
| Christophe Clec'hSummaryCountry: France Publications
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Detail Information
Publications
Multiple-center evaluation of mortality associated with acute kidney injury in critically ill patients: a competing risks analysisChristophe Clec'h
Medical Surgical Intensive Care Unit, Avicenne Teaching Hospital, 125 route de Stalingrad, Bobigny Cedex, France
Crit Care 15:R128. 2011..In this study, we aimed to assess the association between acute kidney injury (AKI) and mortality in critically ill patients using an original competing risks approach...
Tracheostomy does not improve the outcome of patients requiring prolonged mechanical ventilation: a propensity analysisChristophe Clec'h
Intensive Care Unit, Avicenne Teaching Hospital, 125 route de Stalingrad, 93000 Bobigny, France
Crit Care Med 35:132-8. 2007..To examine the association between the performance of a tracheostomy and intensive care unit and postintensive care unit mortality, controlling for treatment selection bias and confounding variables...
Model for predicting short-term mortality of severe sepsisChristophe Adrie
Medical Surgical Intensive Care Unit, Delafontaine Hospital, 93205 Saint Denis, France
Crit Care 13:R72. 2009..To establish a prognostic model for predicting 14-day mortality in ICU patients with severe sepsis overall and according to place of infection acquisition and to sepsis episode number...
Early prediction of Candida glabrata fungemia in nonneutropenic critically ill patientsYves Cohen
Hopital Avicenne, Service de Reanimation, Bobigny, France
Crit Care Med 38:826-30. 2010..Our aim was to determine easy-to-identify risk factors for C. glabrata fungemia likely to guide and improve initial antifungal therapy...
Health-related quality of life in family members of intensive care unit patientsVirginie Lemiale
FAMIREA Group Study, Saint Louis Teaching Hospital, Medical Intensive Care Unit and Biostatistics Department, Paris 7 University, Assistance Publique Hopitaux de Paris, France
J Palliat Med 13:1131-7. 2010..The objective of this study was to evaluate health-related quality of life (HRQOL) in relatives of patients 90 days after ICU discharge or death...
Infectious risk associated with arterial catheters compared with central venous cathetersJean Christophe Lucet
Head of Infection Control Unit, Bichat Claude Bernard University Hospital, Assistance Publique Hopitaux de Paris, Paris
Crit Care Med 38:1030-5. 2010..Arterial catheters are considered at lower risk for catheter-related infection than central venous catheters in the absence of conclusive evidence...
Does catheter-associated urinary tract infection increase mortality in critically ill patients?Carole Schwebel
Medical Surgical Intensive Care Unit, Avicenne Teaching Hospital, Bobigny, France
Infect Control Hosp Epidemiol 28:1367-73. 2007..To produce an accurate estimate of the association between catheter-associated urinary tract infection (UTI) and intensive care unit (ICU) and hospital mortality, controlling for major confounding factors...
Limitations of computed tomographic angiography in the diagnosis of brain deathChristophe Quesnel
Universite Pierre and Marie Curie, Hopital Tenon, Assistance Publique Hopitaux de Paris, Service d Anesthesie Reanimation, 4 rue de la Chine, 75970 Paris Cedex 20, France
Intensive Care Med 33:2129-35. 2007..To evaluate the accuracy of cerebral computed tomographic angiography (CT-a) for the diagnosis of brain death (BD)...
Predicting survival with good neurological recovery at hospital admission after successful resuscitation of out-of-hospital cardiac arrest: the OHCA scoreChristophe Adrie
Intensive Care Unit, Delafontaine Hospital, 2, rue du Dr Delafontaine, Saint Denis, France
Eur Heart J 27:2840-5. 2006..The aim of this study was to develop a simple tool for predicting survival with good neurological function in the overall population of patients with successfully resuscitated cardiac arrest...
Practices in non-neutropenic ICU patients with Candida-positive airway specimensElie Azoulay
Intensive Care Unit, Saint Louis Teaching Hospital, 1 avenue Claude Vellefaux, 75010 Paris, France
Intensive Care Med 30:1384-9. 2004..Design : Closed-item questionnaire with a clinical vignette...
Norepinephrine weaning in septic shock patients by closed loop control based on fuzzy logicMehdi Merouani
SAMU 93 EA 3409, Universite Paris 13, Hopital Avicenne, rue de Stalingrad, 93000 Bobigny, France
Crit Care 12:R155. 2008..We applied fuzzy logic principles to modify intravenous norepinephrine (noradrenaline) infusion rates during norepinephrine infusion in septic patients in order to reduce the duration of shock...
An underrecognized source of organ donors: patients with brain death after successfully resuscitated cardiac arrestChristophe Adrie
Intensive Care Unit, Delafontaine Hospital, 2 rue du Dr Delafontaine, Saint Denis, France
Intensive Care Med 34:132-7. 2008..To identify predictors of brain death after successful resuscitation of out-of-hospital cardiac arrest (OHCA), with the goal of improving the detection of brain death, and to evaluate outcomes of solid organs harvested from these patients...
Postresuscitation disease after cardiac arrest: a sepsis-like syndrome?Christophe Adrie
Intensive Care Unit, Delafontaine Hospital, Saint Denis, France
Curr Opin Crit Care 10:208-12. 2004..This suggests that therapeutic approaches used recently with success in severe sepsis should be investigated in patients successfully resuscitated after cardiac arrest...
Immune status and apoptosis activation during brain deathChristophe Adrie
Intensive Care Unit, Delafontaine Hospital, Saint Denis, France
Shock 33:353-62. 2010..Both abnormalities may play a role in organ dysfunction associated with brain death. However, the level of systemic inflammation or the presence of circulating endotoxin was not associated with lower graft survival...
Reliability of diagnostic coding in intensive care patientsBenoit Misset
Intensive Care Unit, Fondation Hopital Saint Joseph, Universite Paris Descartes, Faculte de Medecine, 185 rue Losserand, 75014 Paris, France
Crit Care 12:R95. 2008..We assessed the reliability of coding between different ICU physicians...
Influence of gender on the outcome of severe sepsis: a reappraisalChristophe Adrie
Medical Surgical ICU, Hopital Delafontaine, 2, rue du Dr Delafontaine, 93205 Sant Denis, France
Chest 132:1786-93. 2007..The influence of gender on survival of patients with severe sepsis is unclear. Earlier studies suggested better survival in women, possibly related to the sex-steroid profile...
Decisions to forgo life-sustaining therapy in ICU patients independently predict hospital deathElie Azoulay
Saint Louis Teaching Hospital, Medical ICU Department, 1 avenue Claude Vellefaux, 75010, Paris, France
Intensive Care Med 29:1895-901. 2003..The objectives of this study were to describe the factors and mortality associated with DFLSTs and to evaluate the potential independent impact of DFLSTs on hospital mortality...
Platelet count decline: an early prognostic marker in critically ill patients with prolonged ICU staysDelphine Moreau
Medical ICU, Saint Louis Teaching Hospital, 1 Ave Claude Vellefaux, 75010 Paris, France
Chest 131:1735-41. 2007..Thrombocytopenia is common in ICU patients. The objective of this study was to evaluate possible links between declining platelet counts early in the ICU stay and survival...
High-volume hemofiltration after out-of-hospital cardiac arrest: a randomized studyIvan Laurent
Medical ICU, Cochin Teaching Hospital, Rene Descartes University, Paris, France
J Am Coll Cardiol 46:432-7. 2005..21 (95% CI, 0.05 to 0.85) in the HF group. CONCLUSIONS: The HF may improve the overall prognosis after resuscitation from OHCA. Combination of HF with mild HT is feasible and should be evaluated in larger trials...
Half the family members of intensive care unit patients do not want to share in the decision-making process: a study in 78 French intensive care unitsElie Azoulay
Intensive Care Unit of the Saint-Louis Teaching Hospital and University of Paris 7, , Paris, France
Crit Care Med 32:1832-8. 2004..Staff members must strive to identify practical and psychological obstacles that may limit their ability to promote autonomy. Finally, they must develop interventions and attitudes capable of empowering families...
Junior versus senior physicians for informing families of intensive care unit patientsDelphine Moreau
, , Paris, France
Am J Respir Crit Care Med 169:512-7. 2004..9 vs. 34.4%, p = 0.004). Specialty residents, if given opportunities for acquiring experience, can become proficient in communicating with families and share this task with senior physicians...
Excess risk of death from intensive care unit-acquired nosocomial bloodstream infections: a reappraisalMaite Garrouste-Orgeas
Medical Surgical Intensive Care Unit, Saint Joseph Hospital, Paris, France corrected
Clin Infect Dis 42:1118-26. 2006..We investigated whether ICU-acquired BSI increased mortality (by > or = 10%) after adjustment for severity of infection at ICU admission and during the pre-BSI stay...
Risk of post-traumatic stress symptoms in family members of intensive care unit patientsElie Azoulay
Service de Reanimation Medicale, Hopital Saint Louis, Paris, France
Am J Respir Crit Care Med 171:987-94. 2005..Intensive care unit (ICU) admission of a relative is a stressful event that may cause symptoms of post-traumatic stress disorder (PTSD)...
Epidemiology and economic evaluation of severe sepsis in France: age, severity, infection site, and place of acquisition (community, hospital, or intensive care unit) as determinants of workload and costChristophe Adrie
Medical-Surgical ICU, Delafontaine Hospital, Saint Denis, France
J Crit Care 20:46-58. 2005..CONCLUSIONS: The wide variations in cost and workload invite efforts to identify patient subgroups most likely to benefit from high-cost treatments and from prevention, particularly targeting severe nosocomial infections...
Impact of unplanned extubation and reintubation after weaning on nosocomial pneumonia risk in the intensive care unit: a prospective multicenter studyArnaud de Lassence
Medical ICU, Avicenne Hospital, Bobigny, France
Anesthesiology 97:148-56. 2002....
Determinants of postintensive care unit mortality: a prospective multicenter studyElie Azoulay
Medical ICU, , Paris, France
Crit Care Med 31:428-32. 2003....
Infectious diseases as a trigger in thrombotic microangiopathies in intensive care unit (ICU) patients?Paul Coppo
Department of Critical Care Medicine, , 1 rue Claude Vellefaux, 75010, Paris, France
Intensive Care Med 29:564-9. 2003..Screening for infection is a requirement in patients with TMA, either idiopathic or associated with other conditions...
A communication strategy and brochure for relatives of patients dying in the ICUAlexandre Lautrette
Saint Louis Hospital and Paris 7 University, Assistance Publique Hopitaux de Paris, France
N Engl J Med 356:469-78. 2007..We evaluated a format that included a proactive end-of-life conference and a brochure to see whether it could lessen the effects of bereavement...
Impact of adverse events on outcomes in intensive care unit patientsMaite Garrouste Orgeas
Medical Surgical ICU, Saint Joseph Hospital Network, Paris, France
Crit Care Med 36:2041-7. 2008..To examine the association between predefined adverse events (AE) (including nosocomial infections) and intensive care unit (ICU) mortality, controlling for multiple adverse events in the same patient and confounding variables...
Opinions about surrogate designation: a population survey in FranceElie Azoulay
The French Famirea Study Group, Intensive Care Unit of the Saint-Louis Teaching Hospital, University Paris 7, , Paris, France
Crit Care Med 31:1711-4. 2003..Primary care physicians should inform their patients about the benefits of discussing illness-related issues among friends and family...
Is methicillin resistance associated with a worse prognosis in Staphylococcus aureus ventilator-associated pneumonia?Jean-Ralph Zahar
Department of Microbiology, Necker Teaching Hospital, Paris, France
Clin Infect Dis 41:1224-31. 2005..After careful adjustment, methicillin resistance did not affect ICU or hospital mortality rates...
Cytokine cascade in sepsisJean Marc Cavaillon
UP Cytokine and Inflammation, Institut Pasteur, Paris, France
Scand J Infect Dis 35:535-44. 2003..Although TNF contributes towards favouring the production of many other cytokines within a complex cascade, there are numerous examples to illustrate that its presence is not a prerequisite for these productions...
Ability of family members to predict patient's consent to critical care researchMagali Ciroldi
Medical Intensive Care Unit, AP HP, Saint Louis Teaching Hospital, Paris 7 University, Paris, France
Intensive Care Med 33:807-13. 2007..The accuracy with which surrogates consent to research on behalf of patients has not been evaluated in the intensive care unit (ICU)...
Impact of a family information leaflet on effectiveness of information provided to family members of intensive care unit patients: a multicenter, prospective, randomized, controlled trialElie Azoulay
Intensive Care Department, Saint Louis Teaching Hospital, Paris 7 University, France
Am J Respir Crit Care Med 165:438-42. 2002..01). These results indicate that ICU caregivers should consider using an FIL to improve the effectiveness of the information they impart to families...
