F Cassim

..synchronization (ERD/ERS) patterns when the movement is sustained? (2) To determine, from a technical point of view for ERD calculation, if it is possible to take the reference period during muscular activation?..

..Promising treatments may be medical (gamma-hydroxybutyric acid) and surgical (deep brain stimulation) although therapeutic abstention may be possible owing to the frequent benign course of the disease...

..This technique allows the averaging of the EEG prior to myoclonus onset (as determined by EMG) in order to reveal a premyoclonic spike that otherwise would remain undetected in the global EEG...

..Subsequently, the changes observed in the post-movement phase might reflect a decrease in (reafferent) sensory inputs and hence impaired their input processing...

..Post-movement beta synchronization can not solely be explained by an idling motor cortex. It may also, at least in part, reflect a movement-related somatosensory processing...

..CONCLUSIONS: These results confirm the fact that motor programming is delayed, and provide some insight into what may well be impaired sensorimotor integration in Parkinson's disease...

..These alterations were accompanied by compensatory mechanisms. SIGNIFICANCE: These age-related alterations during different phases of muscle relaxation could participate to explain global sensorimotor slowing observed with normal aging...

..To study anticipatory postural adjustments (APAs) in Parkinson's disease (PD) via a biomechanical analysis, including vertical torque (Tz)...

..CONCLUSIONS: This study demonstrates that beta ERS depends on the type and quantity of the afferent input. SIGNIFICANCE: This work reinforces the hypothesis of a relationship between beta ERS and processing of afferent inputs...

..To examine the effects of a 30 min, 1 Hz subthreshold rTMS in a case of cortical tremor which is caused by hyperexcitability of sensorimotor cortex...

..L-Dopa partially restored the abnormal mu and beta rhythm cortical (de)synchronisation patterns over the PSM cortex...

..This study used TMS mapping to investigate the motor representation of the abductor pollicis brevis (APB) muscles in a group of patients with focal epilepsy originating in central or pre-central region...

..Moreover, cerebral aging-related changes in the spatio-temporal beta ERS pattern suggests an impaired sensory integration...

..Consequently, additional non-clinical criteria must be identified in order to improve diagnosis while patients are still alive...

..Analysis of the fitted stimulus response curve indicates a dichotomous influence of both low- and high-frequency rTMS on M1 cortical excitability; this may reflect intermingled effects on excitatory and inhibitory cortical networks...

..We aimed to study how low- and high-frequency oscillatory activities are modulated by movement in the contralateral and ipsilateral subcorticocortical loops...

..The aim of the study was to assess the consequences of severe spinothalamic tract lesions resulting from lateral medullary infarct and to show that a specific pain perception can be elicited by strong thermal stimulation...

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..We conclude that afferent-induced facilitation is a mechanism which probably involves muscle spindle afferents and should be considered when studying sensorimotor integration mechanisms in healthy and disease situations...

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..They may improve bradykinesia and cortical deactivation by reestablishing movement-related somatosensory processing at the end of the movement through the basal ganglia into the cortex...

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..Furthermore, AD appears to be more closely related to axonal loss, as demonstrated by spinal cord atrophy, than to demyelinating lesions...

..In myoclonic epileptic syndromes, more useful information can probably be obtained from studies grouping several patients with a same epileptic syndrome than from single case reports...

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..Association with generalized or partial seizures is possible. Other cases in the family are often mentioned with a dominant autosomal transmission. The therapeutic approach is based on the use of antiepileptic drugs...

..2 p.cent of these patients, particularly those who had tremor associated with dystonia (essentially diagnosis of primary writing tremor). CONCLUSION: Polymyography is an effective tool for confirming clinical findings...